SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 5 GLY A 527
LEU A 526
THR A 525
VAL A 631
 None
 0.89A 1ekjF-2xqyA:
undetectable
1ekjG-2xqyA:
undetectable		 1ekjF-2xqyA:
16.26
1ekjG-2xqyA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 8 LEU A 420
THR A 452
LEU A 456
ALA A 413
 None
 0.94A 1fiqC-2xqyA:
1.7		 1fiqC-2xqyA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 12 THR A 396
ARG A 351
VAL A 359
LEU A 338
LEU A 464
 None
 1.32A 1kqwA-2xqyA:
1.2		 1kqwA-2xqyA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 5 ALA A 254
ALA A 313
ALA A 159
VAL A 174
 None
 0.93A 2nyrB-2xqyA:
undetectable		 2nyrB-2xqyA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 12 LEU A 432
LEU A 433
ARG A 339
ALA A 419
LEU A 420
 None
 1.18A 2oz7A-2xqyA:
undetectable		 2oz7A-2xqyA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 11 LEU A 453
ALA A 410
ALA A 413
VAL A 259
LEU A 420
 None
 1.21A 3bszE-2xqyA:
undetectable		 3bszE-2xqyA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 4 LEU A 383
ASP A 373
VAL A 359
THR A 396
 None
 1.30A 3cyxB-2xqyA:
undetectable		 3cyxB-2xqyA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 10 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.27A 3fhjA-2xqyA:
undetectable		 3fhjA-2xqyA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 10 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.27A 3fhjB-2xqyA:
undetectable		 3fhjB-2xqyA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 10 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.27A 3fhjC-2xqyA:
undetectable		 3fhjC-2xqyA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 9 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.27A 3fhjD-2xqyA:
undetectable		 3fhjD-2xqyA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 10 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.27A 3fhjE-2xqyA:
undetectable		 3fhjE-2xqyA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 9 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.27A 3fhjF-2xqyA:
undetectable		 3fhjF-2xqyA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 9 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.27A 3fi0A-2xqyA:
undetectable		 3fi0A-2xqyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 9 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.26A 3fi0C-2xqyA:
undetectable		 3fi0C-2xqyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 9 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.23A 3fi0D-2xqyA:
undetectable		 3fi0D-2xqyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 9 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.31A 3fi0F-2xqyA:
undetectable		 3fi0F-2xqyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 9 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.27A 3fi0H-2xqyA:
undetectable		 3fi0H-2xqyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 8 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.25A 3fi0I-2xqyA:
undetectable		 3fi0I-2xqyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 9 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.26A 3fi0N-2xqyA:
undetectable		 3fi0N-2xqyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 9 GLY A 274
VAL A 163
ILE A 186
VAL A 237
VAL A 279
 None
 1.26A 3fi0R-2xqyA:
undetectable		 3fi0R-2xqyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		3 / 3 GLY A 171
TRP A 142
VAL A 146
 None
 0.54A 3n62B-2xqyA:
undetectable		 3n62B-2xqyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		3 / 3 GLY A 171
TRP A 142
VAL A 146
 None
 0.51A 3n65B-2xqyA:
undetectable		 3n65B-2xqyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		3 / 3 GLY A 171
TRP A 142
VAL A 146
 None
 0.54A 3n66B-2xqyA:
undetectable		 3n66B-2xqyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2xqy A13-D6.3 MONOCLONAL
ANTIBODY
(Mus
musculus) 		3 / 3 TYR G  99
HIS G  58
ARG G  50
 None
 0.74A 4htfA-2xqyG:
undetectable		 4htfA-2xqyG:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 8 ASP A 618
SER A 580
GLY A 582
ALA A 406
 None
 0.85A 4m48A-2xqyA:
1.6		 4m48A-2xqyA:
21.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 2xqy A13-D6.3 MONOCLONAL
ANTIBODY
(Mus
musculus) 		4 / 5 VAL G   2
TYR G  27
ARG G  94
TYR G 102
 None
 0.21A 4m7kH-2xqyG:
27.8		 4m7kH-2xqyG:
56.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 8 VAL A 631
LEU A 622
TYR A 578
ILE A 584
 None
 0.71A 4ma7A-2xqyA:
undetectable		 4ma7A-2xqyA:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 6 LEU A 304
ASP A 434
VAL A 381
ALA A 380
 None
 1.05A 4nkvC-2xqyA:
undetectable		 4nkvC-2xqyA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2xqy A13-D6.3 MONOCLONAL
ANTIBODY
(Mus
musculus) 		3 / 3 SER G 203
ALA G 198
VAL G 197
 None
 0.65A 4o2bC-2xqyG:
undetectable		 4o2bC-2xqyG:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		3 / 3 VAL A 163
ALA A 270
PHE A 319
 None
 0.92A 4olbA-2xqyA:
undetectable		 4olbA-2xqyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		3 / 3 ASP A 618
LYS A 620
LEU A 633
 None
 1.04A 4ptjA-2xqyA:
undetectable		 4ptjA-2xqyA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 6 LEU A 589
LEU A 505
PHE A 511
VAL A 576
 None
 1.11A 4udaA-2xqyA:
undetectable		 4udaA-2xqyA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		3 / 3 VAL A 163
ALA A 270
PHE A 319
 None
 0.89A 4w5nA-2xqyA:
undetectable		 4w5nA-2xqyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2xqy A13-D6.3 MONOCLONAL
ANTIBODY
(Mus
musculus) 		3 / 3 SER G 203
ALA G 198
VAL G 197
 None
 0.58A 4x1iA-2xqyG:
undetectable		 4x1iA-2xqyG:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 11 VAL A 258
VAL A 259
LEU A 420
THR A 416
ALA A 419
 None
 1.33A 4ygfC-2xqyA:
undetectable		 4ygfC-2xqyA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 10 VAL A 258
VAL A 259
LEU A 420
THR A 416
ALA A 419
 None
 1.30A 4yhaB-2xqyA:
undetectable		 4yhaB-2xqyA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 7 THR A 396
LEU A 397
LEU A 385
THR A 400
 None
 0.91A 4z90A-2xqyA:
2.8
4z90B-2xqyA:
2.8
4z90C-2xqyA:
2.8
4z90D-2xqyA:
2.8
4z90E-2xqyA:
2.9		 4z90A-2xqyA:
19.65
4z90B-2xqyA:
19.65
4z90C-2xqyA:
19.65
4z90D-2xqyA:
19.65
4z90E-2xqyA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 10 THR A 400
THR A 396
LEU A 397
LEU A 385
LEU A 464
 None
 0.99A 4z91A-2xqyA:
3.0
4z91B-2xqyA:
2.7
4z91C-2xqyA:
2.8
4z91D-2xqyA:
2.4
4z91E-2xqyA:
3.2		 4z91A-2xqyA:
19.65
4z91B-2xqyA:
19.65
4z91C-2xqyA:
19.65
4z91D-2xqyA:
19.65
4z91E-2xqyA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 5 ALA A 252
ARG A 272
ALA A 424
GLU A 239
 None
 1.30A 5a06C-2xqyA:
undetectable
5a06D-2xqyA:
undetectable		 5a06C-2xqyA:
18.92
5a06D-2xqyA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 12 LEU A 273
VAL A 174
VAL A 163
PHE A 266
LEU A 309
 None
 1.45A 5cymA-2xqyA:
undetectable		 5cymA-2xqyA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2xqy A13-D6.3 MONOCLONAL
ANTIBODY
(Mus
musculus) 		3 / 3 SER G 203
ALA G 198
VAL G 197
 None
 0.53A 5eypA-2xqyG:
undetectable		 5eypA-2xqyG:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 2xqy A13-D6.3 MONOCLONAL
ANTIBODY
(Mus
musculus) 		5 / 12 GLY G  93
GLY G  49
MET G  34
GLY G 106
LEU G  82
 None
 1.13A 5gwxA-2xqyG:
undetectable		 5gwxA-2xqyG:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 12 ALA A 252
HIS A 251
LEU A 255
ALA A 254
LEU A 273
 None
 1.21A 5k9dA-2xqyA:
undetectable		 5k9dA-2xqyA:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 2xqy A13-D6.3 MONOCLONAL
ANTIBODY
(Mus
musculus) 		5 / 5 SER G 112
ALA G 114
PHE G 146
LEU G 170
ASP G 173
 None
 0.33A 5mthA-2xqyG:
29.8		 5mthA-2xqyG:
73.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		5 / 10 VAL A 258
VAL A 259
LEU A 420
THR A 416
ALA A 419
 None
 1.32A 5tt3A-2xqyA:
undetectable		 5tt3A-2xqyA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		3 / 3 GLY A 171
TRP A 142
VAL A 146
 None
 0.54A 5vuoB-2xqyA:
undetectable		 5vuoB-2xqyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 2xqy A13-D6.3 MONOCLONAL
ANTIBODY
ENVELOPE
GLYCOPROTEIN H
(Mus
musculus;
Suid
alphaherpesvirus
1) 		5 / 10 ARG A 364
ASP G 101
GLY G 100
TYR G 102
ALA A 335
 None
 1.48A 5x66D-2xqyA:
undetectable		 5x66D-2xqyA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 2xqy A13-D6.3 MONOCLONAL
ANTIBODY
(Mus
musculus) 		3 / 3 SER G 203
ALA G 198
VAL G 197
 None
 0.54A 5xiwC-2xqyG:
undetectable		 5xiwC-2xqyG:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 2xqy ENVELOPE
GLYCOPROTEIN H
(Suid
alphaherpesvirus
1) 		4 / 4 LEU A 464
ASP A 486
PRO A 487
ARG A 461
 None
 1.17A 6fgdA-2xqyA:
undetectable		 6fgdA-2xqyA:
22.97