SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		5 / 11 PHE A 405
GLU A 404
ALA A 383
GLY A 384
ARG A 118
 None
 1.40A 1l5rA-2xr7A:
undetectable		 1l5rA-2xr7A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		6 / 11 LEU A 145
GLY A 168
ALA A 167
ASP A  28
VAL A  78
VAL A 144
 None
 1.43A 1t7jA-2xr7A:
undetectable		 1t7jA-2xr7A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		4 / 6 TYR A  92
PHE A 319
TYR A 201
LEU A  74
 None
 1.14A 2w98A-2xr7A:
undetectable
2w98B-2xr7A:
undetectable		 2w98A-2xr7A:
21.72
2w98B-2xr7A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		3 / 3 LEU A  41
ARG A  39
ILE A 159
 None
 0.66A 2xn5B-2xr7A:
undetectable		 2xn5B-2xr7A:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		4 / 8 THR A 150
ARG A  38
ILE A  40
SER A 105
 None
 1.01A 2xytE-2xr7A:
undetectable		 2xytE-2xr7A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		4 / 6 ASP A 169
ILE A 173
LEU A  74
TYR A 201
 None
 1.04A 2ya7B-2xr7A:
undetectable		 2ya7B-2xr7A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		4 / 6 ASP A 169
ILE A 173
LEU A  74
TYR A 201
 None
 1.07A 2ya7D-2xr7A:
undetectable		 2ya7D-2xr7A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		5 / 12 THR A  25
GLY A 320
ILE A 173
LEU A  22
VAL A 144
 None
 0.79A 3fzgA-2xr7A:
undetectable		 3fzgA-2xr7A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		5 / 12 LEU A  66
LEU A  20
SER A  13
GLY A  15
SER A  16
 None
 1.07A 3g2oA-2xr7A:
undetectable		 3g2oA-2xr7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		5 / 11 ALA A 167
HIS A 164
GLY A 170
ALA A 171
LEU A  74
 None
 0.95A 3sm2B-2xr7A:
undetectable		 3sm2B-2xr7A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		4 / 8 LEU A 256
VAL A 345
TYR A 276
LEU A 453
 None
 0.90A 3v81A-2xr7A:
undetectable		 3v81A-2xr7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		4 / 8 LEU A 256
VAL A 345
TYR A 276
LEU A 453
 None
 0.90A 3v81C-2xr7A:
2.3		 3v81C-2xr7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		5 / 12 SER A 415
ILE A 408
LEU A 323
PHE A  34
HIS A  35
 None
 1.38A 3vn2A-2xr7A:
undetectable		 3vn2A-2xr7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		5 / 12 VAL A 127
PHE A  42
LEU A 112
TYR A 111
VAL A 406
 None
 1.44A 4po0A-2xr7A:
undetectable		 4po0A-2xr7A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		4 / 8 LEU A 256
VAL A 345
TYR A 276
LEU A 453
 None
 0.93A 4puoC-2xr7A:
2.6		 4puoC-2xr7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		4 / 8 LEU A 256
VAL A 345
TYR A 276
LEU A 453
 None
 0.94A 4pwdA-2xr7A:
2.9		 4pwdA-2xr7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		4 / 8 LEU A 256
VAL A 345
TYR A 276
LEU A 453
 None
 0.93A 4pwdC-2xr7A:
3.0		 4pwdC-2xr7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2xr7 MALONYLTRANSFERASE
(Nicotiana
tabacum) 		4 / 4 TYR A  26
GLY A 365
SER A 364
LEU A 363
 None
 1.46A 5bphC-2xr7A:
undetectable		 5bphC-2xr7A:
23.64