SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xsg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 6 HIS A  99
LEU A 117
TYR A  52
VAL A  82
 None
 1.34A 1ibgH-2xsgA:
2.4		 1ibgH-2xsgA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 7 SER A 489
ASP A 549
GLU A 486
GLU A 482
 None
 1.10A 1knyA-2xsgA:
undetectable
1knyB-2xsgA:
undetectable		 1knyA-2xsgA:
15.09
1knyB-2xsgA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.06A 1liiA-2xsgA:
undetectable		 1liiA-2xsgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.13A 1likA-2xsgA:
undetectable		 1likA-2xsgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 MET A 666
THR A 665
ALA A 663
LEU A  67
 None
 0.90A 1sn5C-2xsgA:
undetectable		 1sn5C-2xsgA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 10 ALA A 673
PHE A 678
LEU A 592
MET A 666
GLY A 664
 None
 1.40A 1uhoA-2xsgA:
undetectable		 1uhoA-2xsgA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLX_B_CIOB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 HIS A 584
THR A 681
PHE A 678
SER A 361
PHE A 357
 None
 1.30A 1xlxB-2xsgA:
undetectable		 1xlxB-2xsgA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 LEU A 381
LEU A 394
GLU A 407
ALA A 352
ALA A 663
 None
 1.10A 2bm9A-2xsgA:
undetectable		 2bm9A-2xsgA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 11 VAL A 335
GLY A 334
ALA A 385
LEU A 394
SER A 409
 None
 1.08A 2bxgA-2xsgA:
2.3		 2bxgA-2xsgA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 TYR A  54
THR A  50
ILE A  59
VAL A 115
ALA A  29
 None
 1.28A 2g72B-2xsgA:
undetectable		 2g72B-2xsgA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 ARG A  42
PRO A 402
SER A 350
GLY A  74
 None
 0.84A 2qd5A-2xsgA:
undetectable		 2qd5A-2xsgA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ALA A 748
PHE A 707
ALA A 745
THR A 740
VAL A 736
 None
 1.26A 2ve3B-2xsgA:
undetectable		 2ve3B-2xsgA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 TYR A 548
SER A 767
GLN A 593
GLN A 686
 None
 1.06A 2xz5B-2xsgA:
undetectable
2xz5E-2xsgA:
undetectable		 2xz5B-2xsgA:
14.54
2xz5E-2xsgA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YK1_H_NCTH300_1
(FAB FRAGMENT, HEAVY
CHAIN
FAB FRAGMENT, LIGHT
CHAIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 10 GLY A 116
VAL A 115
GLU A 106
TYR A  54
TYR A  52
 None
 1.17A 2yk1H-2xsgA:
0.4
2yk1L-2xsgA:
2.3		 2yk1H-2xsgA:
13.82
2yk1L-2xsgA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_C_SPMC503_1
(SPERMIDINE SYNTHASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 TYR A 545
ASP A 464
ASP A 355
GLU A 589
ILE A 590
 None
None
B3P  A1773 (-2.8A)
CA  A1772 (-2.9A)
None
 1.23A 3b7pC-2xsgA:
undetectable		 3b7pC-2xsgA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 11 VAL A  81
LEU A  80
GLY A  61
ILE A  59
LYS A  58
 None
 1.15A 3bjwB-2xsgA:
undetectable		 3bjwB-2xsgA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 11 VAL A  81
LEU A  80
GLY A  61
ILE A  59
LYS A  58
 None
 1.24A 3bjwE-2xsgA:
undetectable		 3bjwE-2xsgA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 VAL A  81
LEU A  80
GLY A  61
ILE A  59
LYS A  58
 None
 1.18A 3bjwF-2xsgA:
undetectable		 3bjwF-2xsgA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 11 VAL A  81
LEU A  80
GLY A  61
ILE A  59
LYS A  58
 None
 1.13A 3bjwH-2xsgA:
undetectable		 3bjwH-2xsgA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 GLY A  51
ASN A  40
PHE A 101
TYR A  52
 None
 1.40A 3ccfA-2xsgA:
undetectable		 3ccfA-2xsgA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 10 ILE A 363
ILE A 366
VAL A 293
GLY A 291
TYR A 316
 None
 1.09A 3elzC-2xsgA:
1.7		 3elzC-2xsgA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 7 ARG A  42
PRO A 402
SER A 350
GLY A  74
 None
 1.05A 3hcnA-2xsgA:
undetectable		 3hcnA-2xsgA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 4 GLY A 129
VAL A 120
GLY A  95
THR A  94
 None
 0.86A 3ib2A-2xsgA:
undetectable		 3ib2A-2xsgA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 349
GLY A 395
PHE A 397
ALA A 385
ASP A 384
 None
 1.14A 3keeA-2xsgA:
undetectable		 3keeA-2xsgA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		3 / 3 ARG A 436
ASP A 428
GLN A 376
 None
 0.76A 3lcvB-2xsgA:
undetectable		 3lcvB-2xsgA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 6 LEU A 606
GLU A 603
PRO A 604
ARG A 568
 None
 1.31A 3ltwA-2xsgA:
0.9		 3ltwA-2xsgA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 6 ALA A 136
ILE A 134
HIS A  99
VAL A  82
 None
 0.89A 3nneG-2xsgA:
undetectable		 3nneG-2xsgA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 ILE A 699
TYR A 701
ASP A 703
SER A 705
 None
 0.42A 3pwwA-2xsgA:
undetectable		 3pwwA-2xsgA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 11 GLY A 462
PRO A 491
GLY A 456
PRO A 455
ASP A 464
 None
 1.50A 3t8nD-2xsgA:
2.1
3t8nF-2xsgA:
2.1		 3t8nD-2xsgA:
10.66
3t8nF-2xsgA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 7 ALA A 552
TYR A 548
ARG A 485
ALA A 488
 None
 1.06A 3twpB-2xsgA:
2.7		 3twpB-2xsgA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 7 ALA A 552
TYR A 548
ARG A 485
ALA A 488
 None
 1.03A 3twpC-2xsgA:
undetectable		 3twpC-2xsgA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.07A 3uboB-2xsgA:
undetectable		 3uboB-2xsgA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 VAL A 375
TYR A 348
VAL A 412
ILE A 363
 None
 1.13A 4aftD-2xsgA:
undetectable
4aftE-2xsgA:
2.2		 4aftD-2xsgA:
14.54
4aftE-2xsgA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.06A 4e3aA-2xsgA:
undetectable		 4e3aA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 TYR A 149
LEU A 238
VAL A 161
VAL A  81
 None
 0.92A 4em2A-2xsgA:
undetectable		 4em2A-2xsgA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 11 ILE A 366
PHE A 694
ALA A 674
ALA A 673
VAL A 362
 None
 1.17A 4h1nA-2xsgA:
undetectable		 4h1nA-2xsgA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 5 PRO A 368
ASP A 367
ILE A 699
VAL A 671
 None
 1.35A 4hytA-2xsgA:
undetectable		 4hytA-2xsgA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 MET A 666
THR A 665
ALA A 663
LEU A  67
 None
 0.96A 4iizB-2xsgA:
undetectable		 4iizB-2xsgA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 MET A 751
LEU A 747
ALA A 724
LEU A 726
 None
 0.83A 4iizB-2xsgA:
undetectable		 4iizB-2xsgA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 MET A 751
LEU A 747
ALA A 724
LEU A 726
 None
 0.73A 4ik6B-2xsgA:
undetectable		 4ik6B-2xsgA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.06A 4jkuB-2xsgA:
undetectable		 4jkuB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.05A 4k8kA-2xsgA:
undetectable		 4k8kA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.06A 4k8pA-2xsgA:
undetectable		 4k8pA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4k8pB-2xsgA:
undetectable		 4k8pB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.05A 4k8tA-2xsgA:
undetectable		 4k8tA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4k8tB-2xsgA:
undetectable		 4k8tB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.05A 4k93A-2xsgA:
undetectable		 4k93A-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.06A 4k93B-2xsgA:
undetectable		 4k93B-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4k9cA-2xsgA:
undetectable		 4k9cA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.05A 4k9cB-2xsgA:
undetectable		 4k9cB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4k9iA-2xsgA:
undetectable		 4k9iA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.03A 4k9iB-2xsgA:
undetectable		 4k9iB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4kadA-2xsgA:
undetectable		 4kadA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4kadB-2xsgA:
undetectable		 4kadB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.05A 4kahA-2xsgA:
undetectable		 4kahA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4kahB-2xsgA:
undetectable		 4kahB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4kalB-2xsgA:
undetectable		 4kalB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.06A 4kanB-2xsgA:
undetectable		 4kanB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4kbeA-2xsgA:
undetectable		 4kbeA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.05A 4kbeB-2xsgA:
undetectable		 4kbeB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 8 LEU A 117
LEU A 159
ILE A  59
HIS A  64
VAL A 138
 None
 1.37A 4klaA-2xsgA:
undetectable		 4klaA-2xsgA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 ARG A  42
PRO A 402
SER A 350
GLY A  74
 None
 0.98A 4klrB-2xsgA:
undetectable		 4klrB-2xsgA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 7 VAL A 214
ALA A 212
PHE A 240
TYR A 149
 None
 1.04A 4lb2A-2xsgA:
undetectable		 4lb2A-2xsgA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.06A 4lbgA-2xsgA:
undetectable		 4lbgA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.05A 4lbgB-2xsgA:
undetectable		 4lbgB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4lbxA-2xsgA:
undetectable		 4lbxA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.04A 4lbxB-2xsgA:
undetectable		 4lbxB-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.05A 4lc4A-2xsgA:
undetectable		 4lc4A-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.05A 4lc4B-2xsgA:
undetectable		 4lc4B-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ASP A 660
GLY A  71
GLY A  72
ASN A  49
THR A 626
 None
B3P  A1773 (-3.3A)
B3P  A1773 (-4.1A)
None
None
 1.05A 4lcaA-2xsgA:
undetectable		 4lcaA-2xsgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 ARG A  42
PRO A 402
SER A 350
GLY A  74
 None
 1.03A 4mk4A-2xsgA:
undetectable		 4mk4A-2xsgA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 ILE A 248
HIS A 147
HIS A  64
PHE A 240
 None
 0.92A 4n16A-2xsgA:
undetectable		 4n16A-2xsgA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 7 ASP A 162
THR A 165
ARG A  42
SER A  60
 None
 1.33A 4o4dA-2xsgA:
undetectable		 4o4dA-2xsgA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 6 MET A 655
ILE A 363
ILE A 366
VAL A 362
 None
 0.89A 4olmA-2xsgA:
undetectable		 4olmA-2xsgA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 THR A 165
GLY A  77
ASN A  66
ASP A  78
SER A 173
 None
 1.38A 4pooB-2xsgA:
undetectable		 4pooB-2xsgA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 5 GLN A 465
LEU A 468
SER A 469
ASP A 551
 None
 1.30A 4qtuD-2xsgA:
undetectable		 4qtuD-2xsgA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 6 SER A 350
GLY A  69
ASP A 356
ASP A  68
 None
 0.92A 4uckB-2xsgA:
undetectable		 4uckB-2xsgA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 7 ALA A 587
SER A 585
ILE A 590
LEU A 592
 None
 1.01A 4uymA-2xsgA:
undetectable		 4uymA-2xsgA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 PHE A 731
GLY A 676
LEU A 677
VAL A 741
THR A 740
 None
 1.06A 4wnwA-2xsgA:
undetectable		 4wnwA-2xsgA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 LEU A 315
MET A 318
VAL A 675
ALA A 674
ILE A 366
 None
 1.04A 4x1yD-2xsgA:
undetectable		 4x1yD-2xsgA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 6 ILE A 295
VAL A 714
THR A 616
ARG A 309
 None
 1.06A 4xe5A-2xsgA:
undetectable		 4xe5A-2xsgA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 5 SER A 144
ARG A 148
GLY A 249
GLU A 247
 None
 1.13A 5btiA-2xsgA:
undetectable
5btiB-2xsgA:
undetectable		 5btiA-2xsgA:
20.46
5btiB-2xsgA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 5 SER A 144
ARG A 148
GLY A 249
GLU A 247
 None
 1.11A 5btiC-2xsgA:
undetectable
5btiD-2xsgA:
undetectable		 5btiC-2xsgA:
20.46
5btiD-2xsgA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 PHE A 529
GLY A 537
ASP A 355
ARG A 405
 None
None
B3P  A1773 (-2.8A)
B3P  A1773 (-3.9A)
 1.00A 5gqbA-2xsgA:
undetectable		 5gqbA-2xsgA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 ALA A  98
THR A  63
LYS A  58
ILE A  59
GLN A  56
 None
 0.98A 5hgcA-2xsgA:
undetectable		 5hgcA-2xsgA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 10 ALA A  37
ALA A 139
GLY A 111
ALA A  32
THR A 282
 None
 1.17A 5lf3H-2xsgA:
undetectable
5lf3I-2xsgA:
undetectable		 5lf3H-2xsgA:
16.39
5lf3I-2xsgA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 10 ALA A  37
ALA A 139
GLY A 111
ALA A  32
THR A 282
 None
 1.18A 5lf3V-2xsgA:
undetectable
5lf3W-2xsgA:
undetectable		 5lf3V-2xsgA:
16.39
5lf3W-2xsgA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		3 / 3 MET A 751
GLN A 722
ARG A 750
 None
 1.08A 5m35B-2xsgA:
2.9		 5m35B-2xsgA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		3 / 3 VAL A 411
LYS A 359
MET A 669
 None
 1.02A 5nknA-2xsgA:
1.5		 5nknA-2xsgA:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 7 ASP A 662
GLY A  69
ASP A 355
ASP A 660
 CA  A1772 (-3.0A)
None
B3P  A1773 (-2.8A)
None
 0.97A 5nnwD-2xsgA:
undetectable		 5nnwD-2xsgA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 7 ASP A 662
GLY A  69
ASP A 355
ASP A 660
 CA  A1772 (-3.0A)
None
B3P  A1773 (-2.8A)
None
 0.86A 5no9D-2xsgA:
undetectable		 5no9D-2xsgA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 5 ALA A 108
VAL A 115
PHE A  16
ILE A  59
 None
 0.95A 5of1A-2xsgA:
undetectable		 5of1A-2xsgA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 5 ALA A 108
VAL A 115
PHE A  16
ILE A  59
 None
 0.85A 5of1B-2xsgA:
undetectable		 5of1B-2xsgA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		3 / 3 GLU A 638
ARG A 622
TYR A 623
 None
 0.28A 5trqB-2xsgA:
undetectable		 5trqB-2xsgA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 6 ASN A 324
ALA A 325
PRO A 322
TYR A 347
 None
 1.20A 5umd2-2xsgA:
undetectable
5umdF-2xsgA:
undetectable		 5umd2-2xsgA:
6.16
5umdF-2xsgA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		6 / 12 GLN A  31
GLY A  77
LEU A  67
GLY A  75
GLY A  76
PRO A 402
 None
 1.13A 5wyqB-2xsgA:
undetectable		 5wyqB-2xsgA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 ALA A 663
THR A 665
THR A 668
ALA A 682
 None
 0.89A 5x2tI-2xsgA:
undetectable
5x2tJ-2xsgA:
undetectable
5x2tK-2xsgA:
undetectable
5x2tL-2xsgA:
undetectable		 5x2tI-2xsgA:
11.71
5x2tJ-2xsgA:
11.07
5x2tK-2xsgA:
11.71
5x2tL-2xsgA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 12 TYR A 365
GLY A 743
VAL A 689
VAL A 736
ASP A 737
 None
 1.13A 6bxlB-2xsgA:
undetectable		 6bxlB-2xsgA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 9 VAL A 191
ASP A  78
LEU A 187
VAL A 160
ASP A 162
 None
 1.36A 6c2mD-2xsgA:
undetectable		 6c2mD-2xsgA:
7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 10 GLY A 449
TYR A 441
ASP A 546
TYR A 548
VAL A 411
 None
 1.28A 6cgdA-2xsgA:
1.6		 6cgdA-2xsgA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		5 / 11 THR A 346
ALA A  32
THR A 253
LEU A 254
ALA A 262
 None
 1.48A 6efnA-2xsgA:
undetectable		 6efnA-2xsgA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		3 / 3 MET A 751
GLN A 722
ARG A 750
 None
 1.11A 6fn9A-2xsgA:
2.8		 6fn9A-2xsgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		3 / 3 MET A 751
GLN A 722
ARG A 750
 None
 1.11A 6fnaB-2xsgA:
3.1		 6fnaB-2xsgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		3 / 3 MET A 751
GLN A 722
ARG A 750
 None
 1.12A 6fnbA-2xsgA:
2.9		 6fnbA-2xsgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		4 / 8 VAL A 721
GLN A 688
ASN A 599
PRO A 604
 None
 0.93A 6hzpA-2xsgA:
undetectable		 6hzpA-2xsgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2xsg CCMAN5
(Cellulosimicrobi
um
cellulans) 		3 / 3 ARG A 372
PHE A 360
PHE A 345
 None
 1.03A 6nknC-2xsgA:
2.1
6nknJ-2xsgA:
undetectable		 6nknC-2xsgA:
14.16
6nknJ-2xsgA:
6.57