SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xt4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		4 / 7 ILE A  64
PHE A  76
PHE A 102
PHE A 112
 None
 1.07A 1e71M-2xt4A:
undetectable		 1e71M-2xt4A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		4 / 7 ILE A  64
PHE A  76
PHE A 102
PHE A 112
 None
 1.09A 1e72M-2xt4A:
undetectable		 1e72M-2xt4A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		3 / 3 GLU A  14
TYR A  11
PHE A  16
 None
 0.86A 1eqbB-2xt4A:
undetectable		 1eqbB-2xt4A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		3 / 3 GLU A  14
TYR A  11
PHE A  16
 None
 0.86A 1eqbA-2xt4A:
undetectable		 1eqbA-2xt4A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		3 / 3 GLU A  14
TYR A  11
PHE A  16
 None
 0.85A 1eqbD-2xt4A:
undetectable		 1eqbD-2xt4A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		3 / 3 GLU A  14
TYR A  11
PHE A  16
 None
 0.86A 1eqbC-2xt4A:
undetectable		 1eqbC-2xt4A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		3 / 3 GLY A 149
ASP A 129
ASN A 167
 None
 0.60A 1vq1A-2xt4A:
undetectable		 1vq1A-2xt4A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		4 / 4 THR A 143
VAL A 120
GLY A 159
THR A 158
 None
 1.09A 3cflA-2xt4A:
undetectable		 3cflA-2xt4A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		4 / 7 PHE A  31
PHE A  51
PHE A  16
LEU A  46
 None
 1.10A 4ejgA-2xt4A:
undetectable		 4ejgA-2xt4A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		3 / 3 ASP A 146
VAL A 123
ASN A 108
 None
 0.78A 4lmnA-2xt4A:
undetectable		 4lmnA-2xt4A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		5 / 10 SER A 145
PHE A 142
ASN A 108
LEU A 107
SER A 101
 None
 1.41A 5l1fD-2xt4A:
undetectable		 5l1fD-2xt4A:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		5 / 12 ALA A 140
GLY A 119
LEU A 157
PHE A 142
LEU A 147
 None
 1.17A 5w7pA-2xt4A:
undetectable		 5w7pA-2xt4A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		4 / 8 PHE A  41
ILE A  64
THR A  69
PHE A  51
 None
 1.16A 5x23A-2xt4A:
undetectable		 5x23A-2xt4A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 2xt4 MCBG-LIKE PROTEIN
(Xanthomonas
albilineans) 		4 / 6 GLU A  32
ARG A  30
ARG A  52
ASP A  10
 None
 1.26A 5zw4A-2xt4A:
undetectable		 5zw4A-2xt4A:
20.08