SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xvg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.14A 1dz4A-2xvgA:
undetectable		 1dz4A-2xvgA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.12A 1dz4B-2xvgA:
undetectable		 1dz4B-2xvgA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.13A 1dz9A-2xvgA:
undetectable		 1dz9A-2xvgA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ILE A 211
GLY A 186
GLY A 676
ILE A 675
ILE A 417
 None
 0.76A 1hxbA-2xvgA:
undetectable		 1hxbA-2xvgA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 TYR A 771
LEU A 891
SER A 889
GLU A 885
 None
None
None
CL  A1993 (-3.3A)
 1.03A 1i7zA-2xvgA:
undetectable		 1i7zA-2xvgA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.36A 1k2rA-2xvgA:
undetectable
1k2rB-2xvgA:
undetectable		 1k2rA-2xvgA:
19.94
1k2rB-2xvgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 1k2sA-2xvgA:
undetectable
1k2sB-2xvgA:
undetectable		 1k2sA-2xvgA:
19.94
1k2sB-2xvgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 1k2tA-2xvgA:
0.5
1k2tB-2xvgA:
undetectable		 1k2tA-2xvgA:
19.94
1k2tB-2xvgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 1k2tA-2xvgA:
0.5
1k2tB-2xvgA:
undetectable		 1k2tA-2xvgA:
19.94
1k2tB-2xvgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 1k2uA-2xvgA:
undetectable
1k2uB-2xvgA:
undetectable		 1k2uA-2xvgA:
19.94
1k2uB-2xvgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 TRP A 656
ARG A 738
GLY A 741
ASP A 688
 None
 1.41A 1kf6M-2xvgA:
undetectable
1kf6N-2xvgA:
undetectable		 1kf6M-2xvgA:
20.16
1kf6N-2xvgA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 1lzzA-2xvgA:
undetectable
1lzzB-2xvgA:
undetectable		 1lzzA-2xvgA:
19.94
1lzzB-2xvgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 1m00A-2xvgA:
0.5
1m00B-2xvgA:
undetectable		 1m00A-2xvgA:
19.94
1m00B-2xvgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 1m00A-2xvgA:
0.5
1m00B-2xvgA:
undetectable		 1m00A-2xvgA:
19.94
1m00B-2xvgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 1mmvA-2xvgA:
undetectable
1mmvB-2xvgA:
undetectable		 1mmvA-2xvgA:
19.94
1mmvB-2xvgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 GLY A 132
VAL A  65
LEU A  58
LEU A  60
LEU A  70
 None
 0.88A 1mx1F-2xvgA:
undetectable		 1mx1F-2xvgA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 5 ASP A 666
VAL A 661
SER A 662
GLN A 189
 None
 1.50A 1n2xB-2xvgA:
undetectable		 1n2xB-2xvgA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 GLY A 436
VAL A 883
MET A 773
LEU A 772
LEU A 779
 None
 1.09A 1nhzA-2xvgA:
undetectable		 1nhzA-2xvgA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.31A 1odiA-2xvgA:
undetectable		 1odiA-2xvgA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.31A 1odiB-2xvgA:
undetectable		 1odiB-2xvgA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.34A 1odiC-2xvgA:
undetectable		 1odiC-2xvgA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.28A 1odiD-2xvgA:
undetectable		 1odiD-2xvgA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.32A 1odiE-2xvgA:
undetectable		 1odiE-2xvgA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.29A 1odiF-2xvgA:
undetectable		 1odiF-2xvgA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 1om4A-2xvgA:
undetectable
1om4B-2xvgA:
undetectable		 1om4A-2xvgA:
19.68
1om4B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 1om4A-2xvgA:
undetectable
1om4B-2xvgA:
undetectable		 1om4A-2xvgA:
19.68
1om4B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.36A 1om5A-2xvgA:
undetectable
1om5B-2xvgA:
undetectable		 1om5A-2xvgA:
19.77
1om5B-2xvgA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 1om5A-2xvgA:
undetectable
1om5B-2xvgA:
undetectable		 1om5A-2xvgA:
19.77
1om5B-2xvgA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 1p6iA-2xvgA:
undetectable
1p6iB-2xvgA:
undetectable		 1p6iA-2xvgA:
19.77
1p6iB-2xvgA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 1p6jA-2xvgA:
undetectable
1p6jB-2xvgA:
undetectable		 1p6jA-2xvgA:
19.77
1p6jB-2xvgA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 1p6jA-2xvgA:
undetectable
1p6jB-2xvgA:
undetectable		 1p6jA-2xvgA:
19.77
1p6jB-2xvgA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 1p6kA-2xvgA:
undetectable
1p6kB-2xvgA:
undetectable		 1p6kA-2xvgA:
19.57
1p6kB-2xvgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.45A 1pw7A-2xvgA:
undetectable		 1pw7A-2xvgA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ASP A 234
ASN A 199
SER A 394
ARG A 171
 None
 1.35A 1rqpB-2xvgA:
undetectable		 1rqpB-2xvgA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 1rs6A-2xvgA:
undetectable
1rs6B-2xvgA:
undetectable		 1rs6A-2xvgA:
19.77
1rs6B-2xvgA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 1rs7A-2xvgA:
undetectable
1rs7B-2xvgA:
undetectable		 1rs7A-2xvgA:
19.77
1rs7B-2xvgA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 1rs7A-2xvgA:
undetectable
1rs7B-2xvgA:
undetectable		 1rs7A-2xvgA:
19.77
1rs7B-2xvgA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 ILE A 211
GLY A 186
GLY A 676
ILE A 675
ILE A 417
 None
 0.86A 1sdtA-2xvgA:
undetectable		 1sdtA-2xvgA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ILE A 211
GLY A 186
GLY A 676
ILE A 675
ILE A 417
 None
 0.88A 1sduA-2xvgA:
undetectable		 1sduA-2xvgA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 ILE A 211
GLY A 186
GLY A 676
ILE A 675
ILE A 417
 None
 0.84A 1sdvA-2xvgA:
undetectable		 1sdvA-2xvgA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		3 / 3 PRO A 162
ASP A 159
ASP A 164
 None
None
SO4  A1995 (-2.7A)
 0.61A 1sqfA-2xvgA:
undetectable		 1sqfA-2xvgA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 LEU A 145
LEU A  58
VAL A 134
PHE A 136
ILE A  78
 None
 1.06A 1uobA-2xvgA:
undetectable		 1uobA-2xvgA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 THR A 641
HIS A 620
ILE A 209
SER A 653
 None
 0.77A 1utdB-2xvgA:
undetectable
1utdC-2xvgA:
2.7		 1utdB-2xvgA:
5.10
1utdC-2xvgA:
5.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 THR A 641
HIS A 620
ILE A 209
SER A 653
 None
 0.81A 1utdF-2xvgA:
2.7
1utdG-2xvgA:
2.7		 1utdF-2xvgA:
5.10
1utdG-2xvgA:
5.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.10A 1uyuA-2xvgA:
undetectable		 1uyuA-2xvgA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.38A 1vhwA-2xvgA:
undetectable
1vhwD-2xvgA:
undetectable		 1vhwA-2xvgA:
12.75
1vhwD-2xvgA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.38A 1vhwC-2xvgA:
undetectable
1vhwE-2xvgA:
undetectable		 1vhwC-2xvgA:
12.75
1vhwE-2xvgA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.39A 1vhwA-2xvgA:
undetectable
1vhwD-2xvgA:
undetectable		 1vhwA-2xvgA:
12.75
1vhwD-2xvgA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.39A 1vhwC-2xvgA:
undetectable
1vhwE-2xvgA:
undetectable		 1vhwC-2xvgA:
12.75
1vhwE-2xvgA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ALA A  82
ILE A 403
VAL A 134
PHE A 136
LEU A 145
 None
 1.13A 1xozA-2xvgA:
undetectable		 1xozA-2xvgA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		3 / 3 THR A 593
GLU A 237
HIS A 378
 None
 0.89A 1xwfA-2xvgA:
undetectable		 1xwfA-2xvgA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		3 / 3 THR A 593
GLU A 237
HIS A 378
 None
 0.90A 1xwfB-2xvgA:
undetectable		 1xwfB-2xvgA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		3 / 3 THR A 593
GLU A 237
HIS A 378
 None
 0.90A 1xwfC-2xvgA:
undetectable		 1xwfC-2xvgA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 PHE A 136
GLY A 132
VAL A  65
LEU A  58
LEU A  60
 None
 1.05A 1ya4B-2xvgA:
undetectable		 1ya4B-2xvgA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 5 TYR A 435
PRO A 774
THR A 683
THR A 789
 None
 1.43A 1ymxB-2xvgA:
undetectable		 1ymxB-2xvgA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 1zvlA-2xvgA:
undetectable
1zvlB-2xvgA:
undetectable		 1zvlA-2xvgA:
18.79
1zvlB-2xvgA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 1zzqA-2xvgA:
undetectable
1zzqB-2xvgA:
undetectable		 1zzqA-2xvgA:
19.63
1zzqB-2xvgA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		3 / 3 THR A 845
THR A 961
PRO A 960
 None
 0.88A 209dC-2xvgA:
undetectable		 209dC-2xvgA:
1.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ILE A 211
GLY A 186
GLY A 676
ILE A 675
ILE A 417
 None
 0.79A 2avvA-2xvgA:
undetectable		 2avvA-2xvgA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.29A 2g6kA-2xvgA:
undetectable
2g6kB-2xvgA:
undetectable		 2g6kA-2xvgA:
19.84
2g6kB-2xvgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_A_SAMA801_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 GLY A 780
LEU A 779
ARG A 769
ASN A 684
PHE A 638
 None
 1.14A 2h21A-2xvgA:
undetectable		 2h21A-2xvgA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_B_SAMB802_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 GLY A 780
LEU A 779
ARG A 769
ASN A 684
PHE A 638
 None
 1.23A 2h21B-2xvgA:
undetectable		 2h21B-2xvgA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_C_SAMC803_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 GLY A 780
LEU A 779
ARG A 769
ASN A 684
PHE A 638
 None
 1.18A 2h21C-2xvgA:
undetectable		 2h21C-2xvgA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 2hx3A-2xvgA:
undetectable
2hx3B-2xvgA:
undetectable		 2hx3A-2xvgA:
19.68
2hx3B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 2hx3A-2xvgA:
undetectable
2hx3B-2xvgA:
undetectable		 2hx3A-2xvgA:
19.68
2hx3B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 2hx4A-2xvgA:
undetectable
2hx4B-2xvgA:
undetectable		 2hx4A-2xvgA:
19.68
2hx4B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 5 SER A 889
LEU A 892
GLY A 877
ARG A 953
 None
 1.23A 2j2pA-2xvgA:
undetectable
2j2pB-2xvgA:
undetectable		 2j2pA-2xvgA:
12.76
2j2pB-2xvgA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 9 GLU A 237
LYS A 598
GLU A 595
GLU A 398
ILE A 229
 None
 1.24A 2j9dA-2xvgA:
0.0
2j9dB-2xvgA:
0.0
2j9dC-2xvgA:
0.0		 2j9dA-2xvgA:
9.19
2j9dB-2xvgA:
9.19
2j9dC-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 9 GLU A 398
ILE A 229
GLU A 237
LYS A 598
GLU A 595
 None
 1.30A 2j9dA-2xvgA:
0.0
2j9dB-2xvgA:
0.0
2j9dC-2xvgA:
0.0		 2j9dA-2xvgA:
9.19
2j9dB-2xvgA:
9.19
2j9dC-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 9 LYS A 598
GLU A 595
GLU A 398
ILE A 229
GLU A 237
 None
 1.29A 2j9dA-2xvgA:
0.0
2j9dB-2xvgA:
0.0
2j9dC-2xvgA:
0.0		 2j9dA-2xvgA:
9.19
2j9dB-2xvgA:
9.19
2j9dC-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 GLU A 237
LYS A 598
GLU A 595
GLU A 398
ILE A 229
 None
 1.26A 2j9dD-2xvgA:
undetectable
2j9dE-2xvgA:
undetectable
2j9dF-2xvgA:
undetectable		 2j9dD-2xvgA:
9.19
2j9dE-2xvgA:
9.08
2j9dF-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 GLU A 398
ILE A 229
GLU A 237
LYS A 598
GLU A 595
 None
 1.31A 2j9dD-2xvgA:
undetectable
2j9dE-2xvgA:
undetectable
2j9dF-2xvgA:
undetectable		 2j9dD-2xvgA:
9.19
2j9dE-2xvgA:
9.08
2j9dF-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 LYS A 598
GLU A 595
GLU A 398
ILE A 229
GLU A 237
 None
 1.28A 2j9dD-2xvgA:
undetectable
2j9dE-2xvgA:
undetectable
2j9dF-2xvgA:
undetectable		 2j9dD-2xvgA:
9.19
2j9dE-2xvgA:
9.08
2j9dF-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 9 GLU A 237
LYS A 598
GLU A 595
GLU A 398
ILE A 229
 None
 1.27A 2j9dG-2xvgA:
0.0
2j9dH-2xvgA:
0.0
2j9dI-2xvgA:
0.0		 2j9dG-2xvgA:
9.19
2j9dH-2xvgA:
9.19
2j9dI-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 9 GLU A 398
ILE A 229
GLU A 237
LYS A 598
GLU A 595
 None
 1.30A 2j9dG-2xvgA:
0.0
2j9dH-2xvgA:
0.0
2j9dI-2xvgA:
0.0		 2j9dG-2xvgA:
9.19
2j9dH-2xvgA:
9.19
2j9dI-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 9 LYS A 598
GLU A 595
GLU A 398
ILE A 229
GLU A 237
 None
 1.31A 2j9dG-2xvgA:
0.0
2j9dH-2xvgA:
0.0
2j9dI-2xvgA:
0.0		 2j9dG-2xvgA:
9.19
2j9dH-2xvgA:
9.19
2j9dI-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 8 GLU A 398
ILE A 229
GLU A 237
LYS A 598
GLU A 595
 None
 1.29A 2j9dJ-2xvgA:
undetectable
2j9dK-2xvgA:
undetectable
2j9dL-2xvgA:
undetectable		 2j9dJ-2xvgA:
9.19
2j9dK-2xvgA:
9.19
2j9dL-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 8 LYS A 598
GLU A 595
GLU A 398
ILE A 229
GLU A 237
 None
 1.32A 2j9dJ-2xvgA:
undetectable
2j9dK-2xvgA:
undetectable
2j9dL-2xvgA:
undetectable		 2j9dJ-2xvgA:
9.19
2j9dK-2xvgA:
9.19
2j9dL-2xvgA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_1
(PROTEASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ILE A 211
GLY A 186
GLY A 676
ILE A 675
ILE A 417
 None
 0.77A 2o4kA-2xvgA:
undetectable		 2o4kA-2xvgA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 THR A 931
ASP A 929
THR A 897
ASP A 839
 None
 1.11A 2okcB-2xvgA:
undetectable		 2okcB-2xvgA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		3 / 3 ASP A 465
ASN A 466
THR A 686
 None
 0.75A 2pymB-2xvgA:
undetectable		 2pymB-2xvgA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		3 / 3 ASP A 465
ASN A 466
THR A 686
 None
 0.72A 2q63B-2xvgA:
undetectable		 2q63B-2xvgA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 470
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.48A 2qmjA-2xvgA:
35.5		 2qmjA-2xvgA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 511
ASP A 659
PHE A 692
HIS A 740
 None
 0.92A 2qmjA-2xvgA:
35.5		 2qmjA-2xvgA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 LEU A  70
LEU A  68
ILE A  78
ARG A  79
 None
 1.01A 2rlfA-2xvgA:
undetectable
2rlfB-2xvgA:
undetectable		 2rlfA-2xvgA:
3.53
2rlfB-2xvgA:
3.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ASP A 234
ASN A 199
SER A 394
ARG A 171
 None
 1.39A 2v7uB-2xvgA:
undetectable		 2v7uB-2xvgA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
ASP A 582
ASP A 659
PHE A 692
HIS A 740
 None
 0.43A 2x2iA-2xvgA:
31.4		 2x2iA-2xvgA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 587
ASP A 470
ASP A 582
ASP A 659
PHE A 692
 None
 0.87A 2x2iA-2xvgA:
31.4		 2x2iA-2xvgA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 TRP A 580
ARG A 642
TRP A 656
THR A 693
 None
 0.82A 2x2iA-2xvgA:
31.4		 2x2iA-2xvgA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
ASP A 582
ASP A 659
PHE A 692
HIS A 740
 None
 0.44A 2x2iB-2xvgA:
30.2		 2x2iB-2xvgA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 TRP A 580
ARG A 642
TRP A 656
THR A 693
 None
 0.79A 2x2iB-2xvgA:
30.2		 2x2iB-2xvgA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 587
ASP A 470
ASP A 582
ASP A 659
PHE A 692
HIS A 740
 None
 0.78A 2x2iC-2xvgA:
31.4		 2x2iC-2xvgA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
ASP A 582
ASP A 659
PHE A 692
HIS A 740
 None
 0.37A 2x2iD-2xvgA:
8.5		 2x2iD-2xvgA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		3 / 3 VAL A 156
ASN A 226
TRP A 224
 None
 0.99A 2y00B-2xvgA:
undetectable		 2y00B-2xvgA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.19A 2zawA-2xvgA:
undetectable		 2zawA-2xvgA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 GLU A 622
ARG A 650
ILE A 648
LEU A 736
ILE A 639
 None
 1.33A 3adsA-2xvgA:
undetectable		 3adsA-2xvgA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 3b3nA-2xvgA:
undetectable
3b3nB-2xvgA:
undetectable		 3b3nA-2xvgA:
19.68
3b3nB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 3b3nA-2xvgA:
undetectable
3b3nB-2xvgA:
undetectable		 3b3nA-2xvgA:
19.68
3b3nB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3b3oA-2xvgA:
undetectable
3b3oB-2xvgA:
undetectable		 3b3oA-2xvgA:
19.68
3b3oB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3b3oA-2xvgA:
undetectable
3b3oB-2xvgA:
undetectable		 3b3oA-2xvgA:
19.68
3b3oB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.36A 3b3pA-2xvgA:
undetectable
3b3pB-2xvgA:
undetectable		 3b3pA-2xvgA:
19.68
3b3pB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.08A 3fwgA-2xvgA:
undetectable		 3fwgA-2xvgA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3hsnA-2xvgA:
undetectable
3hsnB-2xvgA:
undetectable		 3hsnA-2xvgA:
19.68
3hsnB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3hsoA-2xvgA:
undetectable
3hsoB-2xvgA:
undetectable		 3hsoA-2xvgA:
19.68
3hsoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 3hspA-2xvgA:
undetectable
3hspB-2xvgA:
undetectable		 3hspA-2xvgA:
19.68
3hspB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 3jt3A-2xvgA:
undetectable
3jt3B-2xvgA:
undetectable		 3jt3A-2xvgA:
19.68
3jt3B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.37A 3jt3A-2xvgA:
undetectable
3jt3B-2xvgA:
undetectable		 3jt3A-2xvgA:
19.68
3jt3B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 3jt4A-2xvgA:
undetectable
3jt4B-2xvgA:
0.5		 3jt4A-2xvgA:
19.68
3jt4B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3jt4A-2xvgA:
undetectable
3jt4B-2xvgA:
0.5		 3jt4A-2xvgA:
19.68
3jt4B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3jt5A-2xvgA:
undetectable
3jt5B-2xvgA:
undetectable		 3jt5A-2xvgA:
19.68
3jt5B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3jt5A-2xvgA:
undetectable
3jt5B-2xvgA:
undetectable		 3jt5A-2xvgA:
19.68
3jt5B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3jt6A-2xvgA:
undetectable
3jt6B-2xvgA:
undetectable		 3jt6A-2xvgA:
19.68
3jt6B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3jt7A-2xvgA:
undetectable
3jt7B-2xvgA:
undetectable		 3jt7A-2xvgA:
19.68
3jt7B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3jt7A-2xvgA:
undetectable
3jt7B-2xvgA:
undetectable		 3jt7A-2xvgA:
19.68
3jt7B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3jt8A-2xvgA:
undetectable
3jt8B-2xvgA:
0.5		 3jt8A-2xvgA:
19.68
3jt8B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 3jt8A-2xvgA:
undetectable
3jt8B-2xvgA:
0.5		 3jt8A-2xvgA:
19.68
3jt8B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3jt9A-2xvgA:
undetectable
3jt9B-2xvgA:
undetectable		 3jt9A-2xvgA:
19.68
3jt9B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3jt9A-2xvgA:
undetectable
3jt9B-2xvgA:
undetectable		 3jt9A-2xvgA:
19.68
3jt9B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 3jtaA-2xvgA:
undetectable
3jtaB-2xvgA:
0.0		 3jtaA-2xvgA:
19.68
3jtaB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 3jtaA-2xvgA:
undetectable
3jtaB-2xvgA:
0.0		 3jtaA-2xvgA:
19.68
3jtaB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3jwsA-2xvgA:
0.5
3jwsB-2xvgA:
undetectable		 3jwsA-2xvgA:
19.80
3jwsB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3jwsA-2xvgA:
0.6
3jwsB-2xvgA:
undetectable		 3jwsA-2xvgA:
19.80
3jwsB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3jwtA-2xvgA:
undetectable
3jwtB-2xvgA:
undetectable		 3jwtA-2xvgA:
19.80
3jwtB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3jwuA-2xvgA:
undetectable
3jwuB-2xvgA:
0.5		 3jwuA-2xvgA:
19.80
3jwuB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3jwuA-2xvgA:
undetectable
3jwuB-2xvgA:
0.5		 3jwuA-2xvgA:
19.80
3jwuB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3jwvA-2xvgA:
undetectable
3jwvB-2xvgA:
undetectable		 3jwvA-2xvgA:
19.80
3jwvB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 3jwvA-2xvgA:
undetectable
3jwvB-2xvgA:
undetectable		 3jwvA-2xvgA:
19.80
3jwvB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3jx0A-2xvgA:
undetectable
3jx0B-2xvgA:
undetectable		 3jx0A-2xvgA:
19.47
3jx0B-2xvgA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.36A 3jx1A-2xvgA:
0.5
3jx1B-2xvgA:
undetectable		 3jx1A-2xvgA:
19.47
3jx1B-2xvgA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.29A 3jx6A-2xvgA:
undetectable
3jx6B-2xvgA:
undetectable		 3jx6A-2xvgA:
19.20
3jx6B-2xvgA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 GLY A 186
GLY A 644
ALA A 673
GLY A 674
ILE A 655
 None
 0.93A 3ku1A-2xvgA:
undetectable		 3ku1A-2xvgA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 GLY A 186
GLY A 644
ALA A 673
GLY A 674
ILE A 655
 None
 0.94A 3ku1C-2xvgA:
undetectable		 3ku1C-2xvgA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
TRP A 580
ASP A 582
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.42A 3l4wA-2xvgA:
35.4		 3l4wA-2xvgA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 688
ILE A 660
ASP A 659
ASP A 582
HIS A 740
 None
 1.31A 3l4wA-2xvgA:
35.4		 3l4wA-2xvgA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 576
PHE A 484
TYR A 473
HIS A 482
 None
 1.31A 3lb3A-2xvgA:
undetectable		 3lb3A-2xvgA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3n2rA-2xvgA:
undetectable
3n2rB-2xvgA:
undetectable		 3n2rA-2xvgA:
19.68
3n2rB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 3n2rA-2xvgA:
undetectable
3n2rB-2xvgA:
undetectable		 3n2rA-2xvgA:
19.68
3n2rB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.39A 3n5vA-2xvgA:
undetectable
3n5vB-2xvgA:
undetectable		 3n5vA-2xvgA:
19.68
3n5vB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.36A 3n5yA-2xvgA:
undetectable
3n5yB-2xvgA:
undetectable		 3n5yA-2xvgA:
19.68
3n5yB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 3n5yA-2xvgA:
undetectable
3n5yB-2xvgA:
undetectable		 3n5yA-2xvgA:
19.68
3n5yB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.36A 3n5zA-2xvgA:
undetectable
3n5zB-2xvgA:
undetectable		 3n5zA-2xvgA:
19.68
3n5zB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 3n5zA-2xvgA:
undetectable
3n5zB-2xvgA:
undetectable		 3n5zA-2xvgA:
19.68
3n5zB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3nlkA-2xvgA:
undetectable
3nlkB-2xvgA:
undetectable		 3nlkA-2xvgA:
19.80
3nlkB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 3nlkA-2xvgA:
undetectable
3nlkB-2xvgA:
undetectable		 3nlkA-2xvgA:
19.80
3nlkB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3nlmA-2xvgA:
undetectable
3nlmB-2xvgA:
0.5		 3nlmA-2xvgA:
19.68
3nlmB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3nlmA-2xvgA:
undetectable
3nlmB-2xvgA:
0.5		 3nlmA-2xvgA:
19.68
3nlmB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3nlnA-2xvgA:
undetectable
3nlnB-2xvgA:
undetectable		 3nlnA-2xvgA:
19.80
3nlnB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3nlnA-2xvgA:
undetectable
3nlnB-2xvgA:
undetectable		 3nlnA-2xvgA:
19.80
3nlnB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 3nloA-2xvgA:
undetectable
3nloB-2xvgA:
undetectable		 3nloA-2xvgA:
19.80
3nloB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 3nloA-2xvgA:
undetectable
3nloB-2xvgA:
undetectable		 3nloA-2xvgA:
19.80
3nloB-2xvgA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3nlvA-2xvgA:
undetectable
3nlvB-2xvgA:
undetectable		 3nlvA-2xvgA:
19.68
3nlvB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3nlvA-2xvgA:
undetectable
3nlvB-2xvgA:
undetectable		 3nlvA-2xvgA:
19.68
3nlvB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 3nlwA-2xvgA:
undetectable
3nlwB-2xvgA:
0.5		 3nlwA-2xvgA:
19.68
3nlwB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3nlwA-2xvgA:
undetectable
3nlwB-2xvgA:
0.5		 3nlwA-2xvgA:
19.68
3nlwB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 3nlxA-2xvgA:
undetectable
3nlxB-2xvgA:
undetectable		 3nlxA-2xvgA:
19.68
3nlxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3nlxA-2xvgA:
undetectable
3nlxB-2xvgA:
undetectable		 3nlxA-2xvgA:
19.68
3nlxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 3nlyA-2xvgA:
undetectable
3nlyB-2xvgA:
0.6		 3nlyA-2xvgA:
19.68
3nlyB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3nlzA-2xvgA:
undetectable
3nlzB-2xvgA:
undetectable		 3nlzA-2xvgA:
19.68
3nlzB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 3nm0A-2xvgA:
undetectable
3nm0B-2xvgA:
undetectable		 3nm0A-2xvgA:
19.68
3nm0B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3nm0A-2xvgA:
undetectable
3nm0B-2xvgA:
undetectable		 3nm0A-2xvgA:
19.68
3nm0B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3nnyA-2xvgA:
0.5
3nnyB-2xvgA:
undetectable		 3nnyA-2xvgA:
19.68
3nnyB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3nnyA-2xvgA:
0.5
3nnyB-2xvgA:
undetectable		 3nnyA-2xvgA:
19.68
3nnyB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3nnzA-2xvgA:
undetectable
3nnzB-2xvgA:
undetectable		 3nnzA-2xvgA:
19.68
3nnzB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 3nnzA-2xvgA:
undetectable
3nnzB-2xvgA:
undetectable		 3nnzA-2xvgA:
19.68
3nnzB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
ASP A 582
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.43A 3phaA-2xvgA:
33.6		 3phaA-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 511
ASP A 659
PHE A 692
HIS A 740
 None
 0.99A 3phaA-2xvgA:
33.6		 3phaA-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 TRP A 471
ASP A 582
ARG A 642
TRP A 656
ASP A 659
 EDO  A1997 ( 4.5A)
None
None
None
None
 1.33A 3phaA-2xvgA:
33.6		 3phaA-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 470
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.46A 3phaB-2xvgA:
37.9		 3phaB-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 511
ASP A 659
PHE A 692
HIS A 740
 None
 0.96A 3phaB-2xvgA:
37.9		 3phaB-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 688
ILE A 660
ASP A 659
ASP A 582
HIS A 740
 None
 1.24A 3phaB-2xvgA:
37.9		 3phaB-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
ASP A 582
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.46A 3phaC-2xvgA:
38.2		 3phaC-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 511
ASP A 659
PHE A 692
HIS A 740
 None
 1.00A 3phaC-2xvgA:
38.2		 3phaC-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 470
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.47A 3phaD-2xvgA:
38.1		 3phaD-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 511
ASP A 659
PHE A 692
HIS A 740
 None
 0.96A 3phaD-2xvgA:
38.1		 3phaD-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 3pneA-2xvgA:
undetectable
3pneB-2xvgA:
0.7		 3pneA-2xvgA:
19.68
3pneB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3pneA-2xvgA:
undetectable
3pneB-2xvgA:
0.7		 3pneA-2xvgA:
19.68
3pneB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3pnfA-2xvgA:
undetectable
3pnfB-2xvgA:
undetectable		 3pnfA-2xvgA:
19.68
3pnfB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3pnfA-2xvgA:
undetectable
3pnfB-2xvgA:
undetectable		 3pnfA-2xvgA:
19.68
3pnfB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 3pngA-2xvgA:
undetectable
3pngB-2xvgA:
undetectable		 3pngA-2xvgA:
19.68
3pngB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 470
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.39A 3pocA-2xvgA:
37.9		 3pocA-2xvgA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 580
TRP A 656
PHE A 692
HIS A 740
 None
 0.93A 3pocA-2xvgA:
37.9		 3pocA-2xvgA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 TRP A 471
ASP A 470
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 EDO  A1997 ( 4.5A)
None
None
None
None
None
 0.76A 3pocA-2xvgA:
37.9		 3pocA-2xvgA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 TRP A 471
ASP A 470
TRP A 511
ASP A 659
PHE A 692
HIS A 740
 EDO  A1997 ( 4.5A)
None
None
None
None
None
 0.94A 3pocA-2xvgA:
37.9		 3pocA-2xvgA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 470
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.40A 3pocB-2xvgA:
41.1		 3pocB-2xvgA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 580
TRP A 656
PHE A 692
HIS A 740
 None
 0.97A 3pocB-2xvgA:
41.1		 3pocB-2xvgA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 TRP A 471
ASP A 470
TRP A 511
ASP A 659
PHE A 692
HIS A 740
 EDO  A1997 ( 4.5A)
None
None
None
None
None
 0.96A 3pocB-2xvgA:
41.1		 3pocB-2xvgA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3q99A-2xvgA:
undetectable
3q99B-2xvgA:
undetectable		 3q99A-2xvgA:
19.68
3q99B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 3q99A-2xvgA:
undetectable
3q99B-2xvgA:
undetectable		 3q99A-2xvgA:
19.68
3q99B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3q9aA-2xvgA:
undetectable
3q9aB-2xvgA:
undetectable		 3q9aA-2xvgA:
19.68
3q9aB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 5 PHE A 563
ILE A 567
GLY A 623
HIS A 620
 None
 1.17A 3r0lD-2xvgA:
undetectable		 3r0lD-2xvgA:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3rqjA-2xvgA:
undetectable
3rqjB-2xvgA:
undetectable		 3rqjA-2xvgA:
19.68
3rqjB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3rqjA-2xvgA:
undetectable
3rqjB-2xvgA:
undetectable		 3rqjA-2xvgA:
19.68
3rqjB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3rqkA-2xvgA:
0.5
3rqkB-2xvgA:
0.6		 3rqkA-2xvgA:
19.68
3rqkB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 3rqkA-2xvgA:
0.5
3rqkB-2xvgA:
0.6		 3rqkA-2xvgA:
19.68
3rqkB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 3rqlA-2xvgA:
undetectable
3rqlB-2xvgA:
undetectable		 3rqlA-2xvgA:
19.68
3rqlB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 3rqlA-2xvgA:
0.0
3rqlB-2xvgA:
undetectable		 3rqlA-2xvgA:
19.68
3rqlB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3rqmA-2xvgA:
undetectable
3rqmB-2xvgA:
undetectable		 3rqmA-2xvgA:
19.68
3rqmB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 3rqmA-2xvgA:
undetectable
3rqmB-2xvgA:
undetectable		 3rqmA-2xvgA:
19.68
3rqmB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3rqnA-2xvgA:
undetectable
3rqnB-2xvgA:
undetectable		 3rqnA-2xvgA:
19.68
3rqnB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3rqnA-2xvgA:
undetectable
3rqnB-2xvgA:
undetectable		 3rqnA-2xvgA:
19.68
3rqnB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.38A 3svpA-2xvgA:
0.5
3svpB-2xvgA:
undetectable		 3svpA-2xvgA:
19.68
3svpB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3svpA-2xvgA:
0.5
3svpB-2xvgA:
undetectable		 3svpA-2xvgA:
19.68
3svpB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 3svqA-2xvgA:
0.5
3svqB-2xvgA:
undetectable		 3svqA-2xvgA:
19.68
3svqB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 3svqA-2xvgA:
0.5
3svqB-2xvgA:
undetectable		 3svqA-2xvgA:
19.68
3svqB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 GLY A 741
GLY A 690
ARG A 443
ASP A 470
SER A 440
 None
 1.19A 3tkaA-2xvgA:
undetectable		 3tkaA-2xvgA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 470
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.69A 3topA-2xvgA:
33.5		 3topA-2xvgA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 511
ASP A 659
PHE A 692
HIS A 740
 None
 0.87A 3topA-2xvgA:
33.5		 3topA-2xvgA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 470
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.68A 3topB-2xvgA:
33.4		 3topB-2xvgA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 511
ASP A 659
PHE A 692
HIS A 740
 None
 0.87A 3topB-2xvgA:
33.4		 3topB-2xvgA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3tylA-2xvgA:
undetectable
3tylB-2xvgA:
undetectable		 3tylA-2xvgA:
19.68
3tylB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 3tylA-2xvgA:
undetectable
3tylB-2xvgA:
undetectable		 3tylA-2xvgA:
19.68
3tylB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3tymA-2xvgA:
undetectable
3tymB-2xvgA:
undetectable		 3tymA-2xvgA:
19.68
3tymB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3tynA-2xvgA:
undetectable
3tynB-2xvgA:
undetectable		 3tynA-2xvgA:
19.68
3tynB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 3tynA-2xvgA:
undetectable
3tynB-2xvgA:
undetectable		 3tynA-2xvgA:
19.68
3tynB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3tyoA-2xvgA:
undetectable
3tyoB-2xvgA:
undetectable		 3tyoA-2xvgA:
19.68
3tyoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 3tyoA-2xvgA:
undetectable
3tyoB-2xvgA:
undetectable		 3tyoA-2xvgA:
19.68
3tyoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 ARG A 176
GLY A 151
GLU A 148
GLU A 392
ILE A 403
 None
 1.35A 3uayA-2xvgA:
undetectable		 3uayA-2xvgA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.39A 3ufoA-2xvgA:
undetectable
3ufoB-2xvgA:
undetectable		 3ufoA-2xvgA:
19.68
3ufoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 3ufoA-2xvgA:
undetectable
3ufoB-2xvgA:
undetectable		 3ufoA-2xvgA:
19.68
3ufoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 3ufpA-2xvgA:
undetectable
3ufpB-2xvgA:
undetectable		 3ufpA-2xvgA:
19.68
3ufpB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 3ufpA-2xvgA:
undetectable
3ufpB-2xvgA:
undetectable		 3ufpA-2xvgA:
19.68
3ufpB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3ufqA-2xvgA:
undetectable
3ufqB-2xvgA:
0.4		 3ufqA-2xvgA:
19.68
3ufqB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.37A 3ufqA-2xvgA:
undetectable
3ufqB-2xvgA:
0.4		 3ufqA-2xvgA:
19.68
3ufqB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.42A 3ufrA-2xvgA:
undetectable
3ufrB-2xvgA:
0.3		 3ufrA-2xvgA:
19.68
3ufrB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 3ufrA-2xvgA:
undetectable
3ufrB-2xvgA:
0.4		 3ufrA-2xvgA:
19.68
3ufrB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.36A 3ufsA-2xvgA:
undetectable
3ufsB-2xvgA:
undetectable		 3ufsA-2xvgA:
19.68
3ufsB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 3ufsA-2xvgA:
undetectable
3ufsB-2xvgA:
undetectable		 3ufsA-2xvgA:
19.68
3ufsB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 3uftA-2xvgA:
0.4
3uftB-2xvgA:
undetectable		 3uftA-2xvgA:
19.68
3uftB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 3uftA-2xvgA:
0.5
3uftB-2xvgA:
undetectable		 3uftA-2xvgA:
19.68
3uftB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 3ufuA-2xvgA:
undetectable
3ufuB-2xvgA:
undetectable		 3ufuA-2xvgA:
19.68
3ufuB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 3ufvA-2xvgA:
undetectable
3ufvB-2xvgA:
undetectable		 3ufvA-2xvgA:
19.68
3ufvB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 3ufwA-2xvgA:
undetectable
3ufwB-2xvgA:
0.5		 3ufwA-2xvgA:
19.68
3ufwB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 3ufwA-2xvgA:
undetectable
3ufwB-2xvgA:
0.5		 3ufwA-2xvgA:
19.68
3ufwB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		3 / 3 LYS A 432
ARG A 950
LEU A 887
 None
 1.39A 3v4tE-2xvgA:
undetectable		 3v4tE-2xvgA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
TRP A 580
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.42A 3w37A-2xvgA:
34.7		 3w37A-2xvgA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
TRP A 580
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.44A 3welA-2xvgA:
34.9		 3welA-2xvgA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 470
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.52A 3wemA-2xvgA:
34.5		 3wemA-2xvgA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
TRP A 580
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.51A 3wenA-2xvgA:
34.6		 3wenA-2xvgA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
TRP A 580
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.43A 3weoA-2xvgA:
42.2		 3weoA-2xvgA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.12A 3wrhE-2xvgA:
undetectable		 3wrhE-2xvgA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.11A 3wrjE-2xvgA:
undetectable		 3wrjE-2xvgA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 ALA A 125
LEU A 130
GLY A 132
VAL A  80
LEU A  70
 None
 1.04A 3zosA-2xvgA:
undetectable
3zosB-2xvgA:
undetectable		 3zosA-2xvgA:
16.37
3zosB-2xvgA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 5 HIS A 352
LEU A 241
LEU A 308
ASP A 275
 None
 1.28A 4aqlA-2xvgA:
3.5		 4aqlA-2xvgA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 4c39A-2xvgA:
undetectable
4c39B-2xvgA:
undetectable		 4c39A-2xvgA:
19.68
4c39B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 4c39A-2xvgA:
undetectable
4c39B-2xvgA:
undetectable		 4c39A-2xvgA:
19.68
4c39B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4camA-2xvgA:
undetectable
4camB-2xvgA:
0.5		 4camA-2xvgA:
19.68
4camB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4camA-2xvgA:
undetectable
4camB-2xvgA:
0.5		 4camA-2xvgA:
19.68
4camB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 4canA-2xvgA:
0.5
4canB-2xvgA:
0.4		 4canA-2xvgA:
19.68
4canB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 4caoA-2xvgA:
undetectable
4caoB-2xvgA:
undetectable		 4caoA-2xvgA:
19.68
4caoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 4caoA-2xvgA:
undetectable
4caoB-2xvgA:
undetectable		 4caoA-2xvgA:
19.68
4caoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 4capA-2xvgA:
undetectable
4capB-2xvgA:
undetectable		 4capA-2xvgA:
19.68
4capB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4caqA-2xvgA:
undetectable
4caqB-2xvgA:
undetectable		 4caqA-2xvgA:
19.68
4caqB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 4caqA-2xvgA:
undetectable
4caqB-2xvgA:
undetectable		 4caqA-2xvgA:
19.68
4caqB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4cdtA-2xvgA:
undetectable
4cdtB-2xvgA:
undetectable		 4cdtA-2xvgA:
19.68
4cdtB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 4cdtA-2xvgA:
undetectable
4cdtB-2xvgA:
undetectable		 4cdtA-2xvgA:
19.68
4cdtB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 642
HIS A 740
LEU A 640
ASP A 582
 None
 1.48A 4cevA-2xvgA:
undetectable
4cevB-2xvgA:
undetectable		 4cevA-2xvgA:
15.12
4cevB-2xvgA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ASP A 582
ARG A 642
HIS A 740
LEU A 640
 None
 1.48A 4cevA-2xvgA:
undetectable
4cevC-2xvgA:
undetectable		 4cevA-2xvgA:
15.12
4cevC-2xvgA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 642
HIS A 740
LEU A 640
ASP A 582
 None
 1.48A 4cevD-2xvgA:
undetectable
4cevE-2xvgA:
undetectable		 4cevD-2xvgA:
15.12
4cevE-2xvgA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 642
HIS A 740
LEU A 640
ASP A 582
 None
 1.47A 4cevE-2xvgA:
undetectable
4cevF-2xvgA:
undetectable		 4cevE-2xvgA:
15.12
4cevF-2xvgA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4ctpA-2xvgA:
undetectable
4ctpB-2xvgA:
undetectable		 4ctpA-2xvgA:
19.68
4ctpB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 4ctpA-2xvgA:
undetectable
4ctpB-2xvgA:
undetectable		 4ctpA-2xvgA:
19.68
4ctpB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4ctqA-2xvgA:
undetectable
4ctqB-2xvgA:
undetectable		 4ctqA-2xvgA:
19.68
4ctqB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 4ctqA-2xvgA:
undetectable
4ctqB-2xvgA:
undetectable		 4ctqA-2xvgA:
19.68
4ctqB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 4ctrA-2xvgA:
0.5
4ctrB-2xvgA:
undetectable		 4ctrA-2xvgA:
19.68
4ctrB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4cttA-2xvgA:
undetectable
4cttB-2xvgA:
undetectable		 4cttA-2xvgA:
19.68
4cttB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 4cttA-2xvgA:
undetectable
4cttB-2xvgA:
undetectable		 4cttA-2xvgA:
19.68
4cttB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4ctuA-2xvgA:
undetectable
4ctuB-2xvgA:
undetectable		 4ctuA-2xvgA:
19.68
4ctuB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4ctvA-2xvgA:
0.4
4ctvB-2xvgA:
0.5		 4ctvA-2xvgA:
19.68
4ctvB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4ctvA-2xvgA:
0.4
4ctvB-2xvgA:
0.5		 4ctvA-2xvgA:
19.68
4ctvB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 4ctwA-2xvgA:
undetectable
4ctwB-2xvgA:
undetectable		 4ctwA-2xvgA:
19.68
4ctwB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4ctxA-2xvgA:
undetectable
4ctxB-2xvgA:
undetectable		 4ctxA-2xvgA:
19.68
4ctxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4ctxA-2xvgA:
undetectable
4ctxB-2xvgA:
undetectable		 4ctxA-2xvgA:
19.68
4ctxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4cx5A-2xvgA:
undetectable
4cx5B-2xvgA:
undetectable		 4cx5A-2xvgA:
19.88
4cx5B-2xvgA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4cx5A-2xvgA:
undetectable
4cx5B-2xvgA:
undetectable		 4cx5A-2xvgA:
19.88
4cx5B-2xvgA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4cx6A-2xvgA:
undetectable
4cx6B-2xvgA:
undetectable		 4cx6A-2xvgA:
19.88
4cx6B-2xvgA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 4cx6A-2xvgA:
undetectable
4cx6B-2xvgA:
undetectable		 4cx6A-2xvgA:
19.88
4cx6B-2xvgA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4d1nA-2xvgA:
undetectable
4d1nB-2xvgA:
undetectable		 4d1nA-2xvgA:
18.44
4d1nB-2xvgA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4d1nA-2xvgA:
undetectable
4d1nB-2xvgA:
undetectable		 4d1nA-2xvgA:
18.44
4d1nB-2xvgA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.30A 4d1nC-2xvgA:
undetectable
4d1nD-2xvgA:
undetectable		 4d1nC-2xvgA:
18.44
4d1nD-2xvgA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 GLN A 187
ASN A 206
LYS A 323
TRP A 350
 None
 1.33A 4d1yA-2xvgA:
undetectable
4d1yB-2xvgA:
undetectable		 4d1yA-2xvgA:
11.60
4d1yB-2xvgA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4d2zA-2xvgA:
undetectable
4d2zB-2xvgA:
undetectable		 4d2zA-2xvgA:
19.68
4d2zB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 4d2zA-2xvgA:
undetectable
4d2zB-2xvgA:
undetectable		 4d2zA-2xvgA:
19.68
4d2zB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4d30A-2xvgA:
undetectable
4d30B-2xvgA:
undetectable		 4d30A-2xvgA:
19.68
4d30B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4d31A-2xvgA:
undetectable
4d31B-2xvgA:
undetectable		 4d31A-2xvgA:
19.68
4d31B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.37A 4d31A-2xvgA:
undetectable
4d31B-2xvgA:
undetectable		 4d31A-2xvgA:
19.68
4d31B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 4d32A-2xvgA:
undetectable
4d32B-2xvgA:
undetectable		 4d32A-2xvgA:
19.68
4d32B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 4d32A-2xvgA:
undetectable
4d32B-2xvgA:
undetectable		 4d32A-2xvgA:
19.68
4d32B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4d3bA-2xvgA:
undetectable
4d3bB-2xvgA:
undetectable		 4d3bA-2xvgA:
19.68
4d3bB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 4d7oA-2xvgA:
undetectable
4d7oB-2xvgA:
undetectable		 4d7oA-2xvgA:
19.68
4d7oB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 4d7oA-2xvgA:
undetectable
4d7oB-2xvgA:
undetectable		 4d7oA-2xvgA:
19.68
4d7oB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4euxA-2xvgA:
undetectable
4euxB-2xvgA:
undetectable		 4euxA-2xvgA:
19.68
4euxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 4euxA-2xvgA:
undetectable
4euxB-2xvgA:
undetectable		 4euxA-2xvgA:
19.68
4euxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ASP A 582
ASN A 348
ASP A 587
GLU A 585
 None
 1.22A 4fevD-2xvgA:
undetectable		 4fevD-2xvgA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ASP A 582
ASN A 348
ASP A 587
GLU A 585
 None
 1.21A 4fexB-2xvgA:
undetectable		 4fexB-2xvgA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 4fvwA-2xvgA:
undetectable
4fvwB-2xvgA:
0.5		 4fvwA-2xvgA:
19.68
4fvwB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.29A 4fvwA-2xvgA:
undetectable
4fvwB-2xvgA:
0.5		 4fvwA-2xvgA:
19.68
4fvwB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4fvxA-2xvgA:
undetectable
4fvxB-2xvgA:
0.5		 4fvxA-2xvgA:
19.68
4fvxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 4fvxA-2xvgA:
undetectable
4fvxB-2xvgA:
0.5		 4fvxA-2xvgA:
19.68
4fvxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 4fvyA-2xvgA:
undetectable
4fvyB-2xvgA:
undetectable		 4fvyA-2xvgA:
19.68
4fvyB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4fvyA-2xvgA:
undetectable
4fvyB-2xvgA:
undetectable		 4fvyA-2xvgA:
19.68
4fvyB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 4fvzA-2xvgA:
undetectable
4fvzB-2xvgA:
undetectable		 4fvzA-2xvgA:
19.68
4fvzB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4fw0A-2xvgA:
undetectable
4fw0B-2xvgA:
undetectable		 4fw0A-2xvgA:
19.68
4fw0B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.30A 4fw0A-2xvgA:
undetectable
4fw0B-2xvgA:
undetectable		 4fw0A-2xvgA:
19.68
4fw0B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.15A 4g3rA-2xvgA:
undetectable		 4g3rA-2xvgA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.15A 4g3rB-2xvgA:
undetectable		 4g3rB-2xvgA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ASP A 582
ASN A 348
ASP A 587
GLU A 585
 None
 1.22A 4gkhJ-2xvgA:
undetectable		 4gkhJ-2xvgA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 4gqeA-2xvgA:
undetectable
4gqeB-2xvgA:
0.5		 4gqeA-2xvgA:
19.68
4gqeB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.30A 4gqeA-2xvgA:
undetectable
4gqeB-2xvgA:
0.5		 4gqeA-2xvgA:
19.68
4gqeB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 4imtA-2xvgA:
0.4
4imtB-2xvgA:
undetectable		 4imtA-2xvgA:
19.68
4imtB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 4imtA-2xvgA:
0.4
4imtB-2xvgA:
undetectable		 4imtA-2xvgA:
19.68
4imtB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.39A 4imwA-2xvgA:
0.5
4imwB-2xvgA:
undetectable		 4imwA-2xvgA:
19.68
4imwB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.42A 4imwA-2xvgA:
0.5
4imwB-2xvgA:
undetectable		 4imwA-2xvgA:
19.68
4imwB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 4jsfA-2xvgA:
undetectable
4jsfB-2xvgA:
undetectable		 4jsfA-2xvgA:
19.68
4jsfB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4jsgA-2xvgA:
undetectable
4jsgB-2xvgA:
undetectable		 4jsgA-2xvgA:
19.68
4jsgB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 4jsgA-2xvgA:
undetectable
4jsgB-2xvgA:
undetectable		 4jsgA-2xvgA:
19.68
4jsgB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4jshA-2xvgA:
undetectable
4jshB-2xvgA:
undetectable		 4jshA-2xvgA:
19.68
4jshB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.38A 4jshA-2xvgA:
undetectable
4jshB-2xvgA:
undetectable		 4jshA-2xvgA:
19.68
4jshB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 4jsiA-2xvgA:
undetectable
4jsiB-2xvgA:
0.0		 4jsiA-2xvgA:
19.68
4jsiB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 4jsiA-2xvgA:
undetectable
4jsiB-2xvgA:
0.0		 4jsiA-2xvgA:
19.68
4jsiB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4jsjA-2xvgA:
undetectable
4jsjB-2xvgA:
undetectable		 4jsjA-2xvgA:
19.68
4jsjB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4jsjA-2xvgA:
undetectable
4jsjB-2xvgA:
undetectable		 4jsjA-2xvgA:
19.68
4jsjB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4k5dA-2xvgA:
undetectable
4k5dB-2xvgA:
0.5		 4k5dA-2xvgA:
19.68
4k5dB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4k5dA-2xvgA:
undetectable
4k5dB-2xvgA:
0.5		 4k5dA-2xvgA:
19.68
4k5dB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4k5eA-2xvgA:
undetectable
4k5eB-2xvgA:
undetectable		 4k5eA-2xvgA:
19.68
4k5eB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4k5eA-2xvgA:
undetectable
4k5eB-2xvgA:
undetectable		 4k5eA-2xvgA:
19.68
4k5eB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 4k5fA-2xvgA:
undetectable
4k5fB-2xvgA:
undetectable		 4k5fA-2xvgA:
19.68
4k5fB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 4k5fA-2xvgA:
undetectable
4k5fB-2xvgA:
undetectable		 4k5fA-2xvgA:
19.68
4k5fB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4k5gA-2xvgA:
undetectable
4k5gB-2xvgA:
undetectable		 4k5gA-2xvgA:
19.68
4k5gB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.30A 4k5gA-2xvgA:
undetectable
4k5gB-2xvgA:
undetectable		 4k5gA-2xvgA:
19.68
4k5gB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4kchA-2xvgA:
undetectable
4kchB-2xvgA:
undetectable		 4kchA-2xvgA:
19.68
4kchB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 4kchA-2xvgA:
undetectable
4kchB-2xvgA:
undetectable		 4kchA-2xvgA:
19.68
4kchB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 4kciA-2xvgA:
undetectable
4kciB-2xvgA:
undetectable		 4kciA-2xvgA:
19.68
4kciB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.38A 4kciA-2xvgA:
undetectable
4kciB-2xvgA:
undetectable		 4kciA-2xvgA:
19.68
4kciB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4kcjA-2xvgA:
undetectable
4kcjB-2xvgA:
undetectable		 4kcjA-2xvgA:
19.68
4kcjB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.30A 4kcjA-2xvgA:
undetectable
4kcjB-2xvgA:
undetectable		 4kcjA-2xvgA:
19.68
4kcjB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4kckA-2xvgA:
0.5
4kckB-2xvgA:
undetectable		 4kckA-2xvgA:
19.68
4kckB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.37A 4kckA-2xvgA:
0.5
4kckB-2xvgA:
undetectable		 4kckA-2xvgA:
19.68
4kckB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4kclA-2xvgA:
undetectable
4kclB-2xvgA:
undetectable		 4kclA-2xvgA:
19.68
4kclB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 4kclA-2xvgA:
undetectable
4kclB-2xvgA:
undetectable		 4kclA-2xvgA:
19.68
4kclB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 4kcmA-2xvgA:
undetectable
4kcmB-2xvgA:
undetectable		 4kcmA-2xvgA:
19.68
4kcmB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4kcnA-2xvgA:
undetectable
4kcnB-2xvgA:
0.4		 4kcnA-2xvgA:
19.68
4kcnB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4kcnA-2xvgA:
undetectable
4kcnB-2xvgA:
0.4		 4kcnA-2xvgA:
19.68
4kcnB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4kcoA-2xvgA:
undetectable
4kcoB-2xvgA:
undetectable		 4kcoA-2xvgA:
19.68
4kcoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 4kcoA-2xvgA:
undetectable
4kcoB-2xvgA:
undetectable		 4kcoA-2xvgA:
19.68
4kcoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 TYR A 896
THR A 894
PHE A 817
PHE A 967
 None
 1.37A 4kf9A-2xvgA:
undetectable		 4kf9A-2xvgA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.16A 4kkyX-2xvgA:
undetectable		 4kkyX-2xvgA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 GLU A 389
GLU A 392
ARG A 171
GLU A 173
 None
 1.31A 4kr3A-2xvgA:
undetectable		 4kr3A-2xvgA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.09A 4l4eA-2xvgA:
undetectable		 4l4eA-2xvgA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 LEU A  68
VAL A  65
VAL A  91
ASP A 404
 None
 1.09A 4l4fA-2xvgA:
undetectable		 4l4fA-2xvgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 LEU A 581
ALA A 434
ILE A 571
HIS A 482
LEU A 469
 None
 1.18A 4l9qB-2xvgA:
undetectable		 4l9qB-2xvgA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4luxA-2xvgA:
undetectable
4luxB-2xvgA:
undetectable		 4luxA-2xvgA:
19.68
4luxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 4luxA-2xvgA:
undetectable
4luxB-2xvgA:
undetectable		 4luxA-2xvgA:
19.68
4luxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		3 / 3 LEU A 736
MET A 791
TYR A 777
 None
 0.94A 4p6xG-2xvgA:
undetectable		 4p6xG-2xvgA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.29A 4uchA-2xvgA:
undetectable
4uchB-2xvgA:
undetectable		 4uchA-2xvgA:
19.31
4uchB-2xvgA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4ugzA-2xvgA:
undetectable
4ugzB-2xvgA:
undetectable		 4ugzA-2xvgA:
19.68
4ugzB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 4ugzA-2xvgA:
undetectable
4ugzB-2xvgA:
undetectable		 4ugzA-2xvgA:
19.68
4ugzB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4uh0A-2xvgA:
undetectable
4uh0B-2xvgA:
0.4		 4uh0A-2xvgA:
19.68
4uh0B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 4uh0A-2xvgA:
undetectable
4uh0B-2xvgA:
0.4		 4uh0A-2xvgA:
19.68
4uh0B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 4uh1A-2xvgA:
undetectable
4uh1B-2xvgA:
0.7		 4uh1A-2xvgA:
19.68
4uh1B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.30A 4uh1A-2xvgA:
undetectable
4uh1B-2xvgA:
0.7		 4uh1A-2xvgA:
19.68
4uh1B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4uh2A-2xvgA:
undetectable
4uh2B-2xvgA:
undetectable		 4uh2A-2xvgA:
19.68
4uh2B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 4uh2A-2xvgA:
undetectable
4uh2B-2xvgA:
undetectable		 4uh2A-2xvgA:
19.68
4uh2B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.30A 4uh3A-2xvgA:
0.5
4uh3B-2xvgA:
0.5		 4uh3A-2xvgA:
19.68
4uh3B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4uh4A-2xvgA:
undetectable
4uh4B-2xvgA:
undetectable		 4uh4A-2xvgA:
19.68
4uh4B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4uh4A-2xvgA:
undetectable
4uh4B-2xvgA:
undetectable		 4uh4A-2xvgA:
19.68
4uh4B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.30A 4uh5A-2xvgA:
undetectable
4uh5B-2xvgA:
undetectable		 4uh5A-2xvgA:
19.40
4uh5B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 4uh6A-2xvgA:
0.4
4uh6B-2xvgA:
undetectable		 4uh6A-2xvgA:
19.40
4uh6B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 4upmA-2xvgA:
undetectable
4upmB-2xvgA:
undetectable		 4upmA-2xvgA:
19.68
4upmB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 4upmA-2xvgA:
undetectable
4upmB-2xvgA:
undetectable		 4upmA-2xvgA:
19.68
4upmB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4upnA-2xvgA:
undetectable
4upnB-2xvgA:
0.4		 4upnA-2xvgA:
19.68
4upnB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 4upnA-2xvgA:
undetectable
4upnB-2xvgA:
0.4		 4upnA-2xvgA:
19.68
4upnB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 4upoA-2xvgA:
undetectable
4upoB-2xvgA:
undetectable		 4upoA-2xvgA:
19.68
4upoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 4upoA-2xvgA:
undetectable
4upoB-2xvgA:
undetectable		 4upoA-2xvgA:
19.68
4upoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 4uppA-2xvgA:
undetectable
4uppB-2xvgA:
undetectable		 4uppA-2xvgA:
19.68
4uppB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 782
ILE A 905
ILE A 923
SER A 921
THR A 778
 None
 1.24A 4uroD-2xvgA:
undetectable		 4uroD-2xvgA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 4 ILE A 464
ASN A 466
ILE A 506
VAL A 499
 None
 1.20A 4uy87-2xvgA:
undetectable		 4uy87-2xvgA:
1.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 4v3vA-2xvgA:
undetectable
4v3vB-2xvgA:
undetectable		 4v3vA-2xvgA:
19.68
4v3vB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.30A 4v3vA-2xvgA:
undetectable
4v3vB-2xvgA:
undetectable		 4v3vA-2xvgA:
19.68
4v3vB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 4v3xA-2xvgA:
undetectable
4v3xB-2xvgA:
0.5		 4v3xA-2xvgA:
19.68
4v3xB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 4v3yA-2xvgA:
undetectable
4v3yB-2xvgA:
undetectable		 4v3yA-2xvgA:
19.68
4v3yB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 4v3yA-2xvgA:
undetectable
4v3yB-2xvgA:
undetectable		 4v3yA-2xvgA:
19.68
4v3yB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 11 GLY A 151
GLU A 147
ALA A 402
ASP A 404
PHE A 174
 None
 1.14A 4wnuC-2xvgA:
undetectable		 4wnuC-2xvgA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.39A 5ad4A-2xvgA:
undetectable
5ad4B-2xvgA:
undetectable		 5ad4A-2xvgA:
19.68
5ad4B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.39A 5ad4A-2xvgA:
undetectable
5ad4B-2xvgA:
undetectable		 5ad4A-2xvgA:
19.68
5ad4B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 5ad5A-2xvgA:
undetectable
5ad5B-2xvgA:
undetectable		 5ad5A-2xvgA:
19.68
5ad5B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.38A 5ad5A-2xvgA:
undetectable
5ad5B-2xvgA:
undetectable		 5ad5A-2xvgA:
19.68
5ad5B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 5ad6A-2xvgA:
undetectable
5ad6B-2xvgA:
undetectable		 5ad6A-2xvgA:
19.68
5ad6B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.37A 5ad6A-2xvgA:
undetectable
5ad6B-2xvgA:
undetectable		 5ad6A-2xvgA:
19.68
5ad6B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.38A 5ad7A-2xvgA:
undetectable
5ad7B-2xvgA:
undetectable		 5ad7A-2xvgA:
19.68
5ad7B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.37A 5ad8A-2xvgA:
0.6
5ad8B-2xvgA:
undetectable		 5ad8A-2xvgA:
19.68
5ad8B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 5ad9A-2xvgA:
undetectable
5ad9B-2xvgA:
undetectable		 5ad9A-2xvgA:
19.68
5ad9B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.39A 5ad9A-2xvgA:
undetectable
5ad9B-2xvgA:
undetectable		 5ad9A-2xvgA:
19.68
5ad9B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 5adaA-2xvgA:
undetectable
5adaB-2xvgA:
undetectable		 5adaA-2xvgA:
19.68
5adaB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 5adaA-2xvgA:
undetectable
5adaB-2xvgA:
undetectable		 5adaA-2xvgA:
19.68
5adaB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 5adcA-2xvgA:
0.6
5adcB-2xvgA:
undetectable		 5adcA-2xvgA:
19.68
5adcB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5adfA-2xvgA:
0.5
5adfB-2xvgA:
undetectable		 5adfA-2xvgA:
19.40
5adfB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 5adgA-2xvgA:
undetectable
5adgB-2xvgA:
undetectable		 5adgA-2xvgA:
19.40
5adgB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 5adgA-2xvgA:
undetectable
5adgB-2xvgA:
undetectable		 5adgA-2xvgA:
19.40
5adgB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 5adiA-2xvgA:
undetectable
5adiB-2xvgA:
undetectable		 5adiA-2xvgA:
19.40
5adiB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.30A 5agkA-2xvgA:
undetectable
5agkB-2xvgA:
undetectable		 5agkA-2xvgA:
19.68
5agkB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 5agkA-2xvgA:
undetectable
5agkB-2xvgA:
undetectable		 5agkA-2xvgA:
19.68
5agkB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 5aglA-2xvgA:
undetectable
5aglB-2xvgA:
undetectable		 5aglA-2xvgA:
19.68
5aglB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 5aglA-2xvgA:
undetectable
5aglB-2xvgA:
undetectable		 5aglA-2xvgA:
19.68
5aglB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5agmA-2xvgA:
undetectable
5agmB-2xvgA:
undetectable		 5agmA-2xvgA:
19.68
5agmB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 5agmA-2xvgA:
undetectable
5agmB-2xvgA:
undetectable		 5agmA-2xvgA:
19.68
5agmB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 5agnA-2xvgA:
undetectable
5agnB-2xvgA:
undetectable		 5agnA-2xvgA:
19.68
5agnB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 5agoA-2xvgA:
undetectable
5agoB-2xvgA:
undetectable		 5agoA-2xvgA:
19.68
5agoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 5agoA-2xvgA:
undetectable
5agoB-2xvgA:
undetectable		 5agoA-2xvgA:
19.68
5agoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 5agpA-2xvgA:
undetectable
5agpB-2xvgA:
0.4		 5agpA-2xvgA:
19.68
5agpB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 5agpA-2xvgA:
undetectable
5agpB-2xvgA:
undetectable		 5agpA-2xvgA:
19.68
5agpB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 TYR A 261
PRO A 292
TYR A 299
LEU A 304
 None
 1.37A 5bmvB-2xvgA:
undetectable		 5bmvB-2xvgA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5fvpA-2xvgA:
undetectable
5fvpB-2xvgA:
undetectable		 5fvpA-2xvgA:
19.68
5fvpB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 5fvpA-2xvgA:
undetectable
5fvpB-2xvgA:
undetectable		 5fvpA-2xvgA:
19.68
5fvpB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 5fvqA-2xvgA:
undetectable
5fvqB-2xvgA:
undetectable		 5fvqA-2xvgA:
19.68
5fvqB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 5fvrA-2xvgA:
undetectable
5fvrB-2xvgA:
undetectable		 5fvrA-2xvgA:
19.68
5fvrB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5fvsA-2xvgA:
undetectable
5fvsB-2xvgA:
undetectable		 5fvsA-2xvgA:
19.68
5fvsB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.30A 5fvuA-2xvgA:
undetectable
5fvuB-2xvgA:
undetectable		 5fvuA-2xvgA:
19.40
5fvuB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.30A 5fvvA-2xvgA:
undetectable
5fvvB-2xvgA:
undetectable		 5fvvA-2xvgA:
19.40
5fvvB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.29A 5fvwA-2xvgA:
undetectable
5fvwB-2xvgA:
undetectable		 5fvwA-2xvgA:
19.40
5fvwB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5fw0A-2xvgA:
undetectable
5fw0B-2xvgA:
undetectable		 5fw0A-2xvgA:
19.68
5fw0B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 5fw0A-2xvgA:
undetectable
5fw0B-2xvgA:
undetectable		 5fw0A-2xvgA:
19.68
5fw0B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 5g0oA-2xvgA:
undetectable
5g0oB-2xvgA:
undetectable		 5g0oA-2xvgA:
19.47
5g0oB-2xvgA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 5g0oA-2xvgA:
undetectable
5g0oB-2xvgA:
undetectable		 5g0oA-2xvgA:
19.47
5g0oB-2xvgA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 470
TRP A 580
ASP A 582
ASP A 659
PHE A 692
HIS A 740
 None
 0.34A 5iefA-2xvgA:
42.2		 5iefA-2xvgA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 TRP A 471
ASP A 470
TRP A 580
ASP A 659
PHE A 692
HIS A 740
 EDO  A1997 ( 4.5A)
None
None
None
None
None
 0.76A 5iefA-2xvgA:
42.2		 5iefA-2xvgA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_2
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 4 ARG A 642
TRP A 656
ASP A 688
ARG A 738
 None
 0.65A 5iefA-2xvgA:
42.2		 5iefA-2xvgA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 ALA A 396
THR A 230
GLY A 400
ALA A 169
SER A 154
 None
 1.36A 5l66K-2xvgA:
undetectable
5l66L-2xvgA:
undetectable		 5l66K-2xvgA:
12.42
5l66L-2xvgA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 ALA A 396
THR A 230
GLY A 400
ALA A 169
SER A 154
 None
 1.36A 5l66Y-2xvgA:
undetectable
5l66Z-2xvgA:
undetectable		 5l66Y-2xvgA:
12.42
5l66Z-2xvgA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 VAL A 883
LEU A 891
PHE A 967
ILE A 905
PHE A 943
 None
 0.94A 5mueA-2xvgA:
1.5		 5mueA-2xvgA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
TRP A 580
ASP A 582
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.44A 5nn6A-2xvgA:
34.1		 5nn6A-2xvgA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 TRP A 471
ASP A 470
TRP A 511
PHE A 692
HIS A 740
 EDO  A1997 ( 4.5A)
None
None
None
None
 1.05A 5nn6A-2xvgA:
34.1		 5nn6A-2xvgA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 TRP A 471
ASP A 470
TRP A 580
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 EDO  A1997 ( 4.5A)
None
None
None
None
None
None
 0.74A 5nn6A-2xvgA:
34.1		 5nn6A-2xvgA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 511
ASP A 659
PHE A 692
HIS A 740
 None
 0.81A 5nn8A-2xvgA:
42.6		 5nn8A-2xvgA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
TRP A 580
ASP A 582
ARG A 642
ASP A 659
PHE A 692
HIS A 740
 None
 0.52A 5nn8A-2xvgA:
42.6		 5nn8A-2xvgA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 8 ILE A 612
ALA A 605
ASP A 553
ILE A  95
 None
 0.89A 5uihA-2xvgA:
undetectable		 5uihA-2xvgA:
5.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 5unrA-2xvgA:
0.4
5unrB-2xvgA:
undetectable		 5unrA-2xvgA:
19.68
5unrB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 5unsA-2xvgA:
0.4
5unsB-2xvgA:
undetectable		 5unsA-2xvgA:
19.68
5unsB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 5unsA-2xvgA:
0.4
5unsB-2xvgA:
undetectable		 5unsA-2xvgA:
19.68
5unsB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 5unuA-2xvgA:
undetectable
5unuB-2xvgA:
0.4		 5unuA-2xvgA:
19.68
5unuB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.38A 5unuA-2xvgA:
undetectable
5unuB-2xvgA:
0.4		 5unuA-2xvgA:
19.68
5unuB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.41A 5unvA-2xvgA:
0.4
5unvB-2xvgA:
undetectable		 5unvA-2xvgA:
19.68
5unvB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 5unwA-2xvgA:
undetectable
5unwB-2xvgA:
undetectable		 5unwA-2xvgA:
19.68
5unwB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 5unxA-2xvgA:
0.5
5unxB-2xvgA:
undetectable		 5unxA-2xvgA:
19.68
5unxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 5unxA-2xvgA:
0.5
5unxB-2xvgA:
undetectable		 5unxA-2xvgA:
19.68
5unxB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 5unyA-2xvgA:
undetectable
5unyB-2xvgA:
undetectable		 5unyA-2xvgA:
19.68
5unyB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 5unyA-2xvgA:
undetectable
5unyB-2xvgA:
undetectable		 5unyA-2xvgA:
19.68
5unyB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.37A 5unzA-2xvgA:
undetectable
5unzB-2xvgA:
undetectable		 5unzA-2xvgA:
19.68
5unzB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.37A 5uo0A-2xvgA:
undetectable
5uo0B-2xvgA:
undetectable		 5uo0A-2xvgA:
19.68
5uo0B-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5uo1A-2xvgA:
0.5
5uo1B-2xvgA:
undetectable		 5uo1A-2xvgA:
19.40
5uo1B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 5uo1A-2xvgA:
0.5
5uo1B-2xvgA:
undetectable		 5uo1A-2xvgA:
19.40
5uo1B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.37A 5uo2A-2xvgA:
undetectable
5uo2B-2xvgA:
undetectable		 5uo2A-2xvgA:
19.40
5uo2B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 5uo2A-2xvgA:
undetectable
5uo2B-2xvgA:
undetectable		 5uo2A-2xvgA:
19.40
5uo2B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 5uo3A-2xvgA:
undetectable
5uo3B-2xvgA:
undetectable		 5uo3A-2xvgA:
19.40
5uo3B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 5uo3A-2xvgA:
undetectable
5uo3B-2xvgA:
undetectable		 5uo3A-2xvgA:
19.40
5uo3B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 5uo4A-2xvgA:
undetectable
5uo4B-2xvgA:
undetectable		 5uo4A-2xvgA:
19.40
5uo4B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 5uo4A-2xvgA:
undetectable
5uo4B-2xvgA:
undetectable		 5uo4A-2xvgA:
19.40
5uo4B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 5uo5A-2xvgA:
undetectable
5uo5B-2xvgA:
undetectable		 5uo5A-2xvgA:
19.40
5uo5B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 5uo6A-2xvgA:
undetectable
5uo6B-2xvgA:
0.5		 5uo6A-2xvgA:
19.40
5uo6B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 5uo7A-2xvgA:
0.5
5uo7B-2xvgA:
undetectable		 5uo7A-2xvgA:
19.40
5uo7B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 PHE A 276
PHE A 377
THR A 270
ALA A 250
GLY A 256
 None
 1.12A 5veuA-2xvgA:
undetectable		 5veuA-2xvgA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 5vuiA-2xvgA:
undetectable
5vuiB-2xvgA:
0.4		 5vuiA-2xvgA:
19.68
5vuiB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.40A 5vujA-2xvgA:
0.5
5vujB-2xvgA:
undetectable		 5vujA-2xvgA:
19.68
5vujB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5vukA-2xvgA:
undetectable
5vukB-2xvgA:
0.2		 5vukA-2xvgA:
19.68
5vukB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 5vukA-2xvgA:
undetectable
5vukB-2xvgA:
0.2		 5vukA-2xvgA:
19.68
5vukB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 5vulA-2xvgA:
undetectable
5vulB-2xvgA:
undetectable		 5vulA-2xvgA:
19.68
5vulB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 5vumA-2xvgA:
undetectable
5vumB-2xvgA:
undetectable		 5vumA-2xvgA:
19.68
5vumB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5vunA-2xvgA:
undetectable
5vunB-2xvgA:
undetectable		 5vunA-2xvgA:
19.68
5vunB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 5vuoA-2xvgA:
0.4
5vuoB-2xvgA:
undetectable		 5vuoA-2xvgA:
19.68
5vuoB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5vupA-2xvgA:
undetectable
5vupB-2xvgA:
0.4		 5vupA-2xvgA:
19.68
5vupB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5vuqA-2xvgA:
undetectable
5vuqB-2xvgA:
undetectable		 5vuqA-2xvgA:
19.68
5vuqB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 5vurA-2xvgA:
0.5
5vurB-2xvgA:
undetectable		 5vurA-2xvgA:
19.68
5vurB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 5vusA-2xvgA:
undetectable
5vusB-2xvgA:
undetectable		 5vusA-2xvgA:
19.68
5vusB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.35A 5vusA-2xvgA:
undetectable
5vusB-2xvgA:
undetectable		 5vusA-2xvgA:
19.68
5vusB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 5vutA-2xvgA:
undetectable
5vutB-2xvgA:
undetectable		 5vutA-2xvgA:
19.68
5vutB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 5vuuA-2xvgA:
undetectable
5vuuB-2xvgA:
undetectable		 5vuuA-2xvgA:
19.68
5vuuB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.36A 5vuuA-2xvgA:
undetectable
5vuuB-2xvgA:
undetectable		 5vuuA-2xvgA:
19.68
5vuuB-2xvgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 5vuvA-2xvgA:
undetectable
5vuvB-2xvgA:
undetectable		 5vuvA-2xvgA:
19.40
5vuvB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 5vuwA-2xvgA:
undetectable
5vuwB-2xvgA:
undetectable		 5vuwA-2xvgA:
19.40
5vuwB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 5vuyA-2xvgA:
undetectable
5vuyB-2xvgA:
undetectable		 5vuyA-2xvgA:
19.40
5vuyB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 5vuzA-2xvgA:
undetectable
5vuzB-2xvgA:
undetectable		 5vuzA-2xvgA:
19.40
5vuzB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 5vuzA-2xvgA:
undetectable
5vuzB-2xvgA:
undetectable		 5vuzA-2xvgA:
19.40
5vuzB-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 5vv0A-2xvgA:
undetectable
5vv0B-2xvgA:
undetectable		 5vv0A-2xvgA:
19.30
5vv0B-2xvgA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 5vv1A-2xvgA:
undetectable
5vv1B-2xvgA:
0.5		 5vv1A-2xvgA:
19.40
5vv1B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 5vv2A-2xvgA:
undetectable
5vv2B-2xvgA:
undetectable		 5vv2A-2xvgA:
19.40
5vv2B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 5vv3A-2xvgA:
0.5
5vv3B-2xvgA:
undetectable		 5vv3A-2xvgA:
19.40
5vv3B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 5vv4A-2xvgA:
0.5
5vv4B-2xvgA:
undetectable		 5vv4A-2xvgA:
19.40
5vv4B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 5vv5A-2xvgA:
undetectable
5vv5B-2xvgA:
0.5		 5vv5A-2xvgA:
19.40
5vv5B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 5vv5A-2xvgA:
undetectable
5vv5B-2xvgA:
0.5		 5vv5A-2xvgA:
19.40
5vv5B-2xvgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 GLY A 609
PRO A 603
ASP A 161
PRO A 160
GLU A 595
 None
 1.26A 5x6yC-2xvgA:
undetectable		 5x6yC-2xvgA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 10 TRP A 580
ASP A 582
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.57A 5x7pA-2xvgA:
33.6		 5x7pA-2xvgA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 TRP A 580
TRP A 656
TRP A 343
PHE A 692
HIS A 740
 None
 0.91A 5x7pA-2xvgA:
33.6		 5x7pA-2xvgA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 6 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.35A 6auqA-2xvgA:
undetectable
6auqB-2xvgA:
undetectable		 6auqA-2xvgA:
6.04
6auqB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 6auqA-2xvgA:
undetectable
6auqB-2xvgA:
undetectable		 6auqA-2xvgA:
6.04
6auqB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 6aurA-2xvgA:
undetectable
6aurB-2xvgA:
undetectable		 6aurA-2xvgA:
6.04
6aurB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 6ausA-2xvgA:
undetectable
6ausB-2xvgA:
undetectable		 6ausA-2xvgA:
6.04
6ausB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 6autA-2xvgA:
undetectable
6autB-2xvgA:
undetectable		 6autA-2xvgA:
6.04
6autB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 6auuA-2xvgA:
undetectable
6auuB-2xvgA:
undetectable		 6auuA-2xvgA:
6.04
6auuB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 6auuA-2xvgA:
undetectable
6auuB-2xvgA:
undetectable		 6auuA-2xvgA:
6.04
6auuB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.32A 6auvA-2xvgA:
undetectable
6auvB-2xvgA:
undetectable		 6auvA-2xvgA:
6.04
6auvB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 6auvA-2xvgA:
undetectable
6auvB-2xvgA:
undetectable		 6auvA-2xvgA:
6.04
6auvB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.34A 6auwA-2xvgA:
undetectable
6auwB-2xvgA:
undetectable		 6auwA-2xvgA:
6.04
6auwB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 6auwA-2xvgA:
undetectable
6auwB-2xvgA:
undetectable		 6auwA-2xvgA:
6.04
6auwB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 6auxA-2xvgA:
undetectable
6auxB-2xvgA:
undetectable		 6auxA-2xvgA:
6.04
6auxB-2xvgA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 6auyA-2xvgA:
undetectable
6auyB-2xvgA:
undetectable		 6auyA-2xvgA:
6.08
6auyB-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 6auzA-2xvgA:
undetectable
6auzB-2xvgA:
undetectable		 6auzA-2xvgA:
6.08
6auzB-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 6av0A-2xvgA:
undetectable
6av0B-2xvgA:
0.5		 6av0A-2xvgA:
6.08
6av0B-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 6av0A-2xvgA:
undetectable
6av0B-2xvgA:
0.5		 6av0A-2xvgA:
6.08
6av0B-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 6av1A-2xvgA:
undetectable
6av1B-2xvgA:
undetectable		 6av1A-2xvgA:
6.08
6av1B-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 6av2A-2xvgA:
0.6
6av2B-2xvgA:
0.5		 6av2A-2xvgA:
6.08
6av2B-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.31A 6av3A-2xvgA:
0.6
6av3B-2xvgA:
0.4		 6av3A-2xvgA:
6.08
6av3B-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 6av4A-2xvgA:
undetectable
6av4B-2xvgA:
undetectable		 6av4A-2xvgA:
6.08
6av4B-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 6av5A-2xvgA:
0.6
6av5B-2xvgA:
undetectable		 6av5A-2xvgA:
6.08
6av5B-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.34A 6av5A-2xvgA:
0.6
6av5B-2xvgA:
undetectable		 6av5A-2xvgA:
6.08
6av5B-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 9 VAL A  80
LEU A 393
VAL A 215
SER A 216
 None
 1.00A 6c2mD-2xvgA:
undetectable		 6c2mD-2xvgA:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 582
ARG A 642
TRP A 656
PHE A 692
HIS A 740
 None
 0.48A 6c9xA-2xvgA:
13.7		 6c9xA-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 582
ARG A 642
TRP A 656
PHE A 692
HIS A 740
 None
 0.50A 6c9xB-2xvgA:
34.0		 6c9xB-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 ASP A 582
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.48A 6c9zA-2xvgA:
32.4		 6c9zA-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 TRP A 471
ASP A 582
ARG A 642
TRP A 656
ASP A 659
 EDO  A1997 ( 4.5A)
None
None
None
None
 1.34A 6c9zA-2xvgA:
32.4		 6c9zA-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 582
ARG A 642
TRP A 656
PHE A 692
HIS A 740
 None
 0.49A 6c9zB-2xvgA:
33.1		 6c9zB-2xvgA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
ASP A 582
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.42A 6ca1A-2xvgA:
37.9		 6ca1A-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 688
ILE A 660
ASP A 659
ASP A 582
HIS A 740
 None
 1.26A 6ca1A-2xvgA:
37.9		 6ca1A-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 TRP A 471
ASP A 470
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 EDO  A1997 ( 4.5A)
None
None
None
None
None
None
 0.70A 6ca1A-2xvgA:
37.9		 6ca1A-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 TRP A 471
ASP A 470
TRP A 580
TRP A 656
PHE A 692
HIS A 740
 EDO  A1997 ( 4.5A)
None
None
None
None
None
 1.13A 6ca1A-2xvgA:
37.9		 6ca1A-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
ASP A 582
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.36A 6ca1B-2xvgA:
36.9		 6ca1B-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 TRP A 471
ASP A 470
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 EDO  A1997 ( 4.5A)
None
None
None
None
None
None
 0.70A 6ca1B-2xvgA:
36.9		 6ca1B-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		6 / 12 TRP A 471
ASP A 470
TRP A 580
TRP A 656
PHE A 692
HIS A 740
 EDO  A1997 ( 4.5A)
None
None
None
None
None
 1.11A 6ca1B-2xvgA:
36.9		 6ca1B-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
ASP A 582
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.43A 6ca3A-2xvgA:
33.7		 6ca3A-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 580
TRP A 656
PHE A 692
HIS A 740
 None
 0.96A 6ca3A-2xvgA:
33.7		 6ca3A-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		7 / 12 ASP A 470
ASP A 582
ARG A 642
TRP A 656
ASP A 659
PHE A 692
HIS A 740
 None
 0.43A 6ca3B-2xvgA:
32.6		 6ca3B-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 12 ASP A 470
TRP A 580
TRP A 656
PHE A 692
HIS A 740
 None
 0.97A 6ca3B-2xvgA:
32.6		 6ca3B-2xvgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.33A 6cicA-2xvgA:
undetectable
6cicB-2xvgA:
undetectable		 6cicA-2xvgA:
6.08
6cicB-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.32A 6cicA-2xvgA:
undetectable
6cicB-2xvgA:
undetectable		 6cicA-2xvgA:
6.08
6cicB-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 ARG A 697
VAL A 717
PHE A 698
GLU A 722
 None
 1.31A 6cidA-2xvgA:
undetectable
6cidB-2xvgA:
undetectable		 6cidA-2xvgA:
6.08
6cidB-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		4 / 7 PHE A 698
GLU A 722
ARG A 697
VAL A 717
 None
 1.33A 6cidA-2xvgA:
undetectable
6cidB-2xvgA:
undetectable		 6cidA-2xvgA:
6.08
6cidB-2xvgA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_B_TRPB502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 2xvg ALPHA XYLOSIDASE
(Cellvibrio
japonicus) 		5 / 10 TYR A 765
ALA A 732
LEU A 866
TYR A 844
VAL A 819
 None
 1.41A 6g2pB-2xvgA:
undetectable		 6g2pB-2xvgA:
17.85