SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xvo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		4 / 5 ILE A  20
PHE A 116
VAL A  12
PHE A 129
 None
 1.15A 2ygnA-2xvoA:
undetectable		 2ygnA-2xvoA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 ARG A  67
ILE A 169
THR A 173
 None
 0.62A 3ia4D-2xvoA:
undetectable		 3ia4D-2xvoA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 GLN A 163
GLU A 160
LYS A  21
 None
 1.22A 3su9A-2xvoA:
undetectable		 3su9A-2xvoA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		5 / 12 PHE A 102
VAL A  72
ILE A 186
ILE A  87
TYR A  25
 None
 1.12A 4a97B-2xvoA:
undetectable
4a97C-2xvoA:
undetectable		 4a97B-2xvoA:
23.20
4a97C-2xvoA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.68A 5qglA-2xvoA:
undetectable		 5qglA-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.70A 5qguA-2xvoA:
undetectable		 5qguA-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.67A 5qgvA-2xvoA:
undetectable		 5qgvA-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.69A 5qgwA-2xvoA:
undetectable		 5qgwA-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.67A 5qgxA-2xvoA:
undetectable		 5qgxA-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.68A 5qh1A-2xvoA:
undetectable		 5qh1A-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.69A 5qh4A-2xvoA:
undetectable		 5qh4A-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.70A 5qh9A-2xvoA:
undetectable		 5qh9A-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.70A 5qhcA-2xvoA:
undetectable		 5qhcA-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.71A 5qheA-2xvoA:
undetectable		 5qheA-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.67A 5qhfA-2xvoA:
undetectable		 5qhfA-2xvoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2xvo SSO1725
(Sulfolobus
solfataricus) 		3 / 3 VAL A  99
VAL A  78
GLN A  90
 None
 0.67A 5qhgA-2xvoA:
undetectable		 5qhgA-2xvoA:
18.36