SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xvr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 2xvr MAJOR CAPSID PROTEIN
10A
(Escherichia
virus
T7) 		4 / 7 VAL A 298
LEU A 303
ILE A 239
ASN A 241
 None
 0.92A 3avpA-2xvrA:
undetectable		 3avpA-2xvrA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 2xvr MAJOR CAPSID PROTEIN
10A
(Escherichia
virus
T7) 		3 / 3 ASN A 315
ALA A 314
ARG A 312
 None
 0.79A 5cvtB-2xvrA:
undetectable		 5cvtB-2xvrA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2xvr MAJOR CAPSID PROTEIN
10A
(Escherichia
virus
T7) 		4 / 5 VAL A 271
PHE A 245
MET A 243
GLY A 237
 None
 1.25A 6hd4A-2xvrA:
undetectable		 6hd4A-2xvrA:
14.38