SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xws'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	2xws	SIROHYDROCHLORIN COBALTOCHELATASE (Archaeoglobus fulgidus)	5 / 10	GLY A 9 VAL A 8 LEU A 79 LEU A 82 ALA A 40	None	1.36A	1pbcA-2xwsA: undetectable	1pbcA-2xwsA: 16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ACK_A_EDRA999_1 (ACETYLCHOLINESTERASE)	2xws	SIROHYDROCHLORIN COBALTOCHELATASE (Archaeoglobus fulgidus)	4 / 7	GLY A 11 TYR A 17 PHE A 68 HIS A 74	None	1.02A	2ackA-2xwsA: undetectable	2ackA-2xwsA: 13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WAN_C_ACTC303_0 (BRANCHPOINT-BRIDGING PROTEIN)	2xws	SIROHYDROCHLORIN COBALTOCHELATASE (Archaeoglobus fulgidus)	3 / 3	ASP A 51 ARG A 47 PRO A 48	None	1.02A	4wanC-2xwsA: undetectable	4wanC-2xwsA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBR_A_ACTA608_0 (SERUM ALBUMIN)	2xws	SIROHYDROCHLORIN COBALTOCHELATASE (Archaeoglobus fulgidus)	3 / 3	LYS A 26 ARG A 27 HIS A 24	None	1.25A	4zbrA-2xwsA: undetectable	4zbrA-2xwsA: 12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA821_0 (GEPHYRIN)	2xws	SIROHYDROCHLORIN COBALTOCHELATASE (Archaeoglobus fulgidus)	3 / 3	ARG A 46 PHE A 41 GLY A 11	None	0.71A	6fgdA-2xwsA: 5.6	6fgdA-2xwsA: 16.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1PBC_A_BHAA396_0","P-HYDROXYBENZOATE HYDROXYLASE","2xws","SIROHYDROCHLORIN COBALTOCHELATASE","Archaeoglobus fulgidus",5,"GLY A   9;VAL A   8;LEU A  79;LEU A  82;ALA A  40","None","1.36A","1pbcA-2xwsA:undetectable","1pbcA-2xwsA:16.46"],["2ACK_A_EDRA999_1","ACETYLCHOLINESTERASE","2xws","SIROHYDROCHLORIN COBALTOCHELATASE","Archaeoglobus fulgidus",4,"GLY A  11;TYR A  17;PHE A  68;HIS A  74","None","1.02A","2ackA-2xwsA:undetectable","2ackA-2xwsA:13.05"],["4WAN_C_ACTC303_0","BRANCHPOINT-BRIDGING PROTEIN","2xws","SIROHYDROCHLORIN COBALTOCHELATASE","Archaeoglobus fulgidus",3,"ASP A  51;ARG A  47;PRO A  48","None","1.02A","4wanC-2xwsA:undetectable","4wanC-2xwsA:20.78"],["4ZBR_A_ACTA608_0","SERUM ALBUMIN","2xws","SIROHYDROCHLORIN COBALTOCHELATASE","Archaeoglobus fulgidus",3,"LYS A  26;ARG A  27;HIS A  24","None","1.25A","4zbrA-2xwsA:undetectable","4zbrA-2xwsA:12.28"],["6FGD_A_ACTA821_0","GEPHYRIN","2xws","SIROHYDROCHLORIN COBALTOCHELATASE","Archaeoglobus fulgidus",3,"ARG A  46;PHE A  41;GLY A  11","None","0.71A","6fgdA-2xwsA:5.6","6fgdA-2xwsA:16.71"]]