SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xxm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 2xxm CAMELID VHH 9
(Vicugna
pacos) 		4 / 8 GLY B  26
ARG B  71
TYR B  79
ASP B  73
 None
 0.89A 5vlmB-2xxmB:
undetectable		 5vlmB-2xxmB:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 2xxm CAMELID VHH 9
(Vicugna
pacos) 		3 / 3 TYR B  59
GLY B  65
THR B  68
 None
 0.16A 6cjkB-2xxmB:
17.5		 6cjkB-2xxmB:
28.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 2xxm CAMELID VHH 9
(Vicugna
pacos) 		4 / 6 ILE B  48
TYR B  90
LEU B  80
VAL B  63
 None
 1.29A 6f6jA-2xxmB:
undetectable		 6f6jA-2xxmB:
undetectable