SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xy3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NU9_A_478A401_1 (PROTEASE)	2xy3	SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS (Bacillus subtilis)	4 / 8	ASP A 9 VAL A 46 GLY A 105 PRO A 43	None	0.77A	3nu9A-2xy3A: undetectable	3nu9A-2xy3A: 16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OCT_A_1N1A663_2 (TYROSINE-PROTEIN KINASE BTK)	2xy3	SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS (Bacillus subtilis)	4 / 5	PHE A 91 ILE A 108 ASN A 87 PHE A 92	DUP A1130 (-3.3A) None None None	1.35A	3octA-2xy3A: undetectable	3octA-2xy3A: 19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WEO_A_ACRA1001_2 (ALPHA-GLUCOSIDASE)	2xy3	SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS (Bacillus subtilis)	4 / 6	ILE A 108 ILE A 113 TRP A 23 TRP A 90	None	1.33A	3weoA-2xy3A: 2.0	3weoA-2xy3A: 8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G1P_A_ACTA403_0 (ADP-RIBOSYLHYDROLASE LIKE 2)	2xy3	SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS (Bacillus subtilis)	3 / 3	TYR A 7 ASP A 9 GLN A 12	None	0.86A	6g1pA-2xy3A: undetectable	6g1pA-2xy3A: 18.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3NU9_A_478A401_1","PROTEASE","2xy3","SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS","Bacillus subtilis",4,"ASP A   9;VAL A  46;GLY A 105;PRO A  43","None","0.77A","3nu9A-2xy3A:undetectable","3nu9A-2xy3A:16.55"],["3OCT_A_1N1A663_2","TYROSINE-PROTEIN KINASE BTK","2xy3","SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS","Bacillus subtilis",4,"PHE A  91;ILE A 108;ASN A  87;PHE A  92","DUP A1130 (-3.3A);None;None;None","1.35A","3octA-2xy3A:undetectable","3octA-2xy3A:19.78"],["3WEO_A_ACRA1001_2","ALPHA-GLUCOSIDASE","2xy3","SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS","Bacillus subtilis",4,"ILE A 108;ILE A 113;TRP A  23;TRP A  90","None","1.33A","3weoA-2xy3A:2.0","3weoA-2xy3A:8.65"],["6G1P_A_ACTA403_0","ADP-RIBOSYLHYDROLASE LIKE 2","2xy3","SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS","Bacillus subtilis",3,"TYR A   7;ASP A   9;GLN A  12","None","0.86A","6g1pA-2xy3A:undetectable","6g1pA-2xy3A:18.43"]]