SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xym'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A52_A_ESTA1_1 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 10	ALA A 88 LEU A 83 LEU A 82 ILE A 253 LEU A 285	None	1.24A	1a52A-2xymA: undetectable	1a52A-2xymA: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A52_B_ESTB2_1 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 10	ALA A 88 LEU A 83 LEU A 82 ILE A 253 LEU A 285	None	1.26A	1a52B-2xymA: undetectable	1a52B-2xymA: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERE_A_ESTA600_1 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 9	ALA A 88 LEU A 83 LEU A 82 ILE A 253 LEU A 285	None	1.32A	1ereA-2xymA: undetectable	1ereA-2xymA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERE_B_ESTB600_1 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 9	ALA A 88 LEU A 83 LEU A 82 ILE A 253 LEU A 285	None	1.31A	1ereB-2xymA: undetectable	1ereB-2xymA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERE_C_ESTC600_1 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 9	ALA A 88 LEU A 83 LEU A 82 ILE A 253 LEU A 285	None	1.31A	1ereC-2xymA: undetectable	1ereC-2xymA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERE_D_ESTD600_1 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 9	ALA A 88 LEU A 83 LEU A 82 ILE A 253 LEU A 285	None	1.30A	1ereD-2xymA: undetectable	1ereD-2xymA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_J_TRPJ81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 8	SER A 96 ALA A 97 GLY A 283 ILE A 160	None	0.69A	1gtnI-2xymA: undetectable 1gtnJ-2xymA: undetectable	1gtnI-2xymA: 10.38 1gtnJ-2xymA: 10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXD_A_ACRA733_1 (ALPHA AMYLASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 6	SER A 453 ASN A 455 LEU A 457 ASP A 458	None	1.30A	1mxdA-2xymA: undetectable	1mxdA-2xymA: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P9G_A_ACTA42_0 (EAFP 2)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	3 / 3	CYH A 366 ARG A 200 CYH A 316	None	1.38A	1p9gA-2xymA: undetectable	1p9gA-2xymA: 6.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PCG_A_ESTA1_1 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 10	ALA A 88 LEU A 83 LEU A 82 ILE A 253 LEU A 285	None	1.22A	1pcgA-2xymA: undetectable	1pcgA-2xymA: 18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QKU_A_ESTA600_1 (ESTRADIOL RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 10	ALA A 88 LEU A 83 LEU A 82 ILE A 253 LEU A 285	None	1.29A	1qkuA-2xymA: undetectable	1qkuA-2xymA: 18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QKU_B_ESTB600_1 (ESTRADIOL RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 10	ALA A 88 LEU A 83 LEU A 82 ILE A 253 LEU A 285	None	1.29A	1qkuB-2xymA: undetectable	1qkuB-2xymA: 18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QKU_C_ESTC600_1 (ESTRADIOL RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 10	ALA A 88 LEU A 83 LEU A 82 ILE A 253 LEU A 285	None	1.29A	1qkuC-2xymA: undetectable	1qkuC-2xymA: 18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_B_EDTB1511_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 8	ARG A 386 ARG A 394 TYR A 38 THR A 40	None None None PO4 A1569 (-4.7A)	1.49A	1zlqB-2xymA: 0.0	1zlqB-2xymA: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	ASP A 125 VAL A 122 ALA A 88 CYH A 170 VAL A 167	None	1.46A	2g70A-2xymA: undetectable	2g70A-2xymA: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G72_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	ASP A 125 VAL A 122 ALA A 88 CYH A 170 VAL A 167	None	1.44A	2g72A-2xymA: undetectable	2g72A-2xymA: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9C_A_ACTA1121_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 5	SER A 431 VAL A 435 SER A 510 VAL A 507	None	1.39A	2j9cA-2xymA: 3.9 2j9cB-2xymA: 3.7 2j9cC-2xymA: 3.5	2j9cA-2xymA: 11.55 2j9cB-2xymA: 11.55 2j9cC-2xymA: 11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_A_SAMA302_1 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	3 / 3	THR A 364 ASP A 318 SER A 288	None	0.74A	2nxeA-2xymA: undetectable	2nxeA-2xymA: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_1 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	3 / 3	THR A 364 ASP A 318 SER A 288	None	0.81A	2nxeB-2xymA: 2.4	2nxeB-2xymA: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OUZ_A_C3DA999_0 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	LEU A 392 LEU A 425 MET A 426 ILE A 463 HIS A 467	None	1.08A	2ouzA-2xymA: undetectable	2ouzA-2xymA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QXS_A_RALA600_1 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	6 / 12	MET A 447 LEU A 392 TRP A 420 LEU A 425 ILE A 463 PRO A 388	None	1.22A	2qxsA-2xymA: undetectable	2qxsA-2xymA: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QXS_B_RALB600_1 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	6 / 12	MET A 447 LEU A 392 TRP A 420 LEU A 425 ILE A 463 PRO A 388	None	1.23A	2qxsB-2xymA: undetectable	2qxsB-2xymA: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VE3_A_REAA1445_1 (PUTATIVE CYTOCHROME P450 120)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	PHE A 526 TRP A 500 ALA A 494 ALA A 396 THR A 399	None	0.99A	2ve3A-2xymA: undetectable	2ve3A-2xymA: 21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VE3_B_REAB1445_1 (PUTATIVE CYTOCHROME P450 120)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	PHE A 526 TRP A 500 ALA A 494 ALA A 396 THR A 399	None	0.96A	2ve3B-2xymA: undetectable	2ve3B-2xymA: 21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 6	ALA A 393 ALA A 396 THR A 399 PHE A 429	None	0.88A	2xfhA-2xymA: undetectable	2xfhA-2xymA: 23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZUJ_A_CAMA422_0 (CAMPHOR 5-MONOOXYGENASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 8	LEU A 384 VAL A 370 VAL A 321 LEU A 314	None	0.79A	2zujA-2xymA: undetectable	2zujA-2xymA: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CYX_A_ROCA201_2 (HIV-1 PROTEASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	3 / 3	ARG A 158 VAL A 284 THR A 287	None	0.72A	3cyxA-2xymA: undetectable	3cyxA-2xymA: 10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 8	ILE A 462 ILE A 463 VAL A 454 ILE A 412	None	0.87A	3p4wC-2xymA: undetectable	3p4wC-2xymA: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q5P_A_TACA7101_1 (MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	VAL A 284 ILE A 178 TYR A 240 GLU A 236 ILE A 233	None	1.33A	3q5pA-2xymA: undetectable	3q5pA-2xymA: 19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TNE_B_RITB401_2 (SECRETED ASPARTIC PROTEASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 7	SER A 190 TYR A 296 VAL A 67 TYR A 219	None	1.06A	3tneB-2xymA: undetectable	3tneB-2xymA: 20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_A_SALA404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 7	ALA A 416 PRO A 417 ARG A 381 ALA A 198	None	1.15A	3twpA-2xymA: undetectable	3twpA-2xymA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WDM_B_ADNB301_1 (4-PHOSPHOPANTOATE--B ETA-ALANINE LIGASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 10	ALA A 519 ARG A 523 GLY A 522 LEU A 439 LEU A 525	None	1.09A	3wdmB-2xymA: undetectable	3wdmB-2xymA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WDM_D_ADND301_1 (4-PHOSPHOPANTOATE--B ETA-ALANINE LIGASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 10	ALA A 519 ARG A 523 GLY A 522 LEU A 439 LEU A 525	None	1.12A	3wdmD-2xymA: undetectable	3wdmD-2xymA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J24_B_ESTB600_1 (ESTROGEN RECEPTOR BETA)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	LEU A 409 LEU A 425 MET A 426 ILE A 462 ILE A 463	None	0.96A	4j24B-2xymA: undetectable	4j24B-2xymA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVL_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.28A	4qvlV-2xymA: undetectable 4qvlb-2xymA: undetectable	4qvlV-2xymA: 17.74 4qvlb-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVL_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.27A	4qvlH-2xymA: undetectable 4qvlN-2xymA: undetectable	4qvlH-2xymA: 17.74 4qvlN-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVM_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.29A	4qvmV-2xymA: undetectable 4qvmb-2xymA: undetectable	4qvmV-2xymA: 17.74 4qvmb-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVM_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.29A	4qvmH-2xymA: undetectable 4qvmN-2xymA: undetectable	4qvmH-2xymA: 17.74 4qvmN-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.29A	4qvpV-2xymA: undetectable 4qvpb-2xymA: undetectable	4qvpV-2xymA: 17.74 4qvpb-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.29A	4qvpH-2xymA: undetectable 4qvpN-2xymA: undetectable	4qvpH-2xymA: 17.74 4qvpN-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.29A	4qvqV-2xymA: undetectable 4qvqb-2xymA: undetectable	4qvqV-2xymA: 17.74 4qvqb-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.29A	4qvqH-2xymA: undetectable 4qvqN-2xymA: undetectable	4qvqH-2xymA: 17.74 4qvqN-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVW_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.28A	4qvwV-2xymA: undetectable 4qvwb-2xymA: undetectable	4qvwV-2xymA: 17.74 4qvwb-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVW_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.28A	4qvwH-2xymA: undetectable 4qvwN-2xymA: undetectable	4qvwH-2xymA: 17.74 4qvwN-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW0_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.29A	4qw0V-2xymA: undetectable 4qw0b-2xymA: undetectable	4qw0V-2xymA: 17.74 4qw0b-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW0_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.28A	4qw0H-2xymA: undetectable 4qw0N-2xymA: undetectable	4qw0H-2xymA: 17.74 4qw0N-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW1_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.28A	4qw1V-2xymA: undetectable 4qw1b-2xymA: undetectable	4qw1V-2xymA: 17.74 4qw1b-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW1_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.28A	4qw1H-2xymA: undetectable 4qw1N-2xymA: undetectable	4qw1H-2xymA: 17.74 4qw1N-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW3_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.29A	4qw3V-2xymA: undetectable 4qw3b-2xymA: undetectable	4qw3V-2xymA: 17.74 4qw3b-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW3_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.29A	4qw3H-2xymA: undetectable 4qw3N-2xymA: undetectable	4qw3H-2xymA: 17.74 4qw3N-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_A_29SA601_1 (ESTROGEN RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	ALA A 395 LEU A 392 TRP A 420 MET A 426 PRO A 388	None	1.31A	4xi3A-2xymA: undetectable	4xi3A-2xymA: 18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BXN_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.27A	5bxnV-2xymA: undetectable 5bxnb-2xymA: undetectable	5bxnV-2xymA: 17.74 5bxnb-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BXN_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.27A	5bxnH-2xymA: undetectable 5bxnN-2xymA: undetectable	5bxnH-2xymA: 17.74 5bxnN-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CZ7_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.27A	5cz7H-2xymA: undetectable 5cz7N-2xymA: undetectable	5cz7H-2xymA: 17.74 5cz7N-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0X_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.28A	5d0xV-2xymA: undetectable 5d0xb-2xymA: undetectable	5d0xV-2xymA: 17.74 5d0xb-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0X_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.28A	5d0xH-2xymA: undetectable 5d0xN-2xymA: undetectable	5d0xH-2xymA: 17.74 5d0xN-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JCN_B_ASCB502_0 (OS09G0567300 PROTEIN)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 6	GLU A 236 GLY A 290 ARG A 280 PHE A 224	None	1.10A	5jcnB-2xymA: undetectable	5jcnB-2xymA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.28A	5l5zV-2xymA: undetectable 5l5zb-2xymA: undetectable	5l5zV-2xymA: 17.74 5l5zb-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.28A	5l5zH-2xymA: undetectable 5l5zN-2xymA: undetectable	5l5zH-2xymA: 17.74 5l5zN-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L66_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.27A	5l66V-2xymA: undetectable 5l66b-2xymA: undetectable	5l66V-2xymA: 17.74 5l66b-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L66_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 11	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.27A	5l66H-2xymA: undetectable 5l66N-2xymA: undetectable	5l66H-2xymA: 17.74 5l66N-2xymA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF3_B_BO2B305_1 (PROTEASOME SUBUNIT BETA TYPE-6)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.33A	5lf3b-2xymA: undetectable	5lf3b-2xymA: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF3_N_BO2N304_1 (PROTEASOME SUBUNIT BETA TYPE-6)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	THR A 136 THR A 137 GLY A 283 ALA A 281 THR A 287	None	1.32A	5lf3N-2xymA: undetectable	5lf3N-2xymA: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	LEU A 285 LEU A 175 ALA A 252 TRP A 123 LEU A 245	None	1.21A	5mwyA-2xymA: undetectable	5mwyA-2xymA: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BRD_B_RFPB502_2 (RIFAMPIN MONOOXYGENASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 6	GLN A 414 VAL A 454 LEU A 384 PRO A 417	None	1.07A	6brdB-2xymA: 1.4	6brdB-2xymA: 9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_T_PCFT101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 10	ASP A 61 TYR A 346 VAL A 297 SER A 190 ALA A 189	None	1.46A	6hu9L-2xymA: undetectable 6hu9P-2xymA: undetectable 6hu9T-2xymA: undetectable	6hu9L-2xymA: 22.70 6hu9P-2xymA: 15.62 6hu9T-2xymA: 7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	7DFR_A_FOLA161_1 (DIHYDROFOLATE REDUCTASE)	2xym	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	3 / 3	ASP A 359 LEU A 362 ARG A 484	None	0.79A	7dfrA-2xymA: undetectable	7dfrA-2xymA: 13.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A52_A_ESTA1_1","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A  88;LEU A  83;LEU A  82;ILE A 253;LEU A 285","None","1.24A","1a52A-2xymA:undetectable","1a52A-2xymA:18.97"],["1A52_B_ESTB2_1","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A  88;LEU A  83;LEU A  82;ILE A 253;LEU A 285","None","1.26A","1a52B-2xymA:undetectable","1a52B-2xymA:18.97"],["1ERE_A_ESTA600_1","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A  88;LEU A  83;LEU A  82;ILE A 253;LEU A 285","None","1.32A","1ereA-2xymA:undetectable","1ereA-2xymA:18.84"],["1ERE_B_ESTB600_1","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A  88;LEU A  83;LEU A  82;ILE A 253;LEU A 285","None","1.31A","1ereB-2xymA:undetectable","1ereB-2xymA:18.84"],["1ERE_C_ESTC600_1","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A  88;LEU A  83;LEU A  82;ILE A 253;LEU A 285","None","1.31A","1ereC-2xymA:undetectable","1ereC-2xymA:18.84"],["1ERE_D_ESTD600_1","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A  88;LEU A  83;LEU A  82;ILE A 253;LEU A 285","None","1.30A","1ereD-2xymA:undetectable","1ereD-2xymA:18.84"],["1GTN_J_TRPJ81_0","TRP RNA-BINDING ATTENUATION PROTEIN","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"SER A  96;ALA A  97;GLY A 283;ILE A 160","None","0.69A","1gtnI-2xymA:undetectable;1gtnJ-2xymA:undetectable","1gtnI-2xymA:10.38;1gtnJ-2xymA:10.38"],["1MXD_A_ACRA733_1","ALPHA AMYLASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"SER A 453;ASN A 455;LEU A 457;ASP A 458","None","1.30A","1mxdA-2xymA:undetectable","1mxdA-2xymA:19.23"],["1P9G_A_ACTA42_0","EAFP 2","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",3,"CYH A 366;ARG A 200;CYH A 316","None","1.38A","1p9gA-2xymA:undetectable","1p9gA-2xymA:6.53"],["1PCG_A_ESTA1_1","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A  88;LEU A  83;LEU A  82;ILE A 253;LEU A 285","None","1.22A","1pcgA-2xymA:undetectable","1pcgA-2xymA:18.92"],["1QKU_A_ESTA600_1","ESTRADIOL RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A  88;LEU A  83;LEU A  82;ILE A 253;LEU A 285","None","1.29A","1qkuA-2xymA:undetectable","1qkuA-2xymA:18.51"],["1QKU_B_ESTB600_1","ESTRADIOL RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A  88;LEU A  83;LEU A  82;ILE A 253;LEU A 285","None","1.29A","1qkuB-2xymA:undetectable","1qkuB-2xymA:18.51"],["1QKU_C_ESTC600_1","ESTRADIOL RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A  88;LEU A  83;LEU A  82;ILE A 253;LEU A 285","None","1.29A","1qkuC-2xymA:undetectable","1qkuC-2xymA:18.51"],["1ZLQ_B_EDTB1511_0","NICKEL-BINDING PERIPLASMIC PROTEIN","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"ARG A 386;ARG A 394;TYR A  38;THR A  40","None;None;None;PO4 A1569 (-4.7A)","1.49A","1zlqB-2xymA:0.0","1zlqB-2xymA:21.75"],["2G70_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ASP A 125;VAL A 122;ALA A  88;CYH A 170;VAL A 167","None","1.46A","2g70A-2xymA:undetectable","2g70A-2xymA:20.07"],["2G72_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ASP A 125;VAL A 122;ALA A  88;CYH A 170;VAL A 167","None","1.44A","2g72A-2xymA:undetectable","2g72A-2xymA:20.07"],["2J9C_A_ACTA1121_0","HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"SER A 431;VAL A 435;SER A 510;VAL A 507","None","1.39A","2j9cA-2xymA:3.9;2j9cB-2xymA:3.7;2j9cC-2xymA:3.5","2j9cA-2xymA:11.55;2j9cB-2xymA:11.55;2j9cC-2xymA:11.55"],["2NXE_A_SAMA302_1","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",3,"THR A 364;ASP A 318;SER A 288","None","0.74A","2nxeA-2xymA:undetectable","2nxeA-2xymA:18.39"],["2NXE_B_SAMB303_1","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",3,"THR A 364;ASP A 318;SER A 288","None","0.81A","2nxeB-2xymA:2.4","2nxeB-2xymA:18.39"],["2OUZ_A_C3DA999_0","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"LEU A 392;LEU A 425;MET A 426;ILE A 463;HIS A 467","None","1.08A","2ouzA-2xymA:undetectable","2ouzA-2xymA:18.84"],["2QXS_A_RALA600_1","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",6,"MET A 447;LEU A 392;TRP A 420;LEU A 425;ILE A 463;PRO A 388","None","1.22A","2qxsA-2xymA:undetectable","2qxsA-2xymA:18.83"],["2QXS_B_RALB600_1","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",6,"MET A 447;LEU A 392;TRP A 420;LEU A 425;ILE A 463;PRO A 388","None","1.23A","2qxsB-2xymA:undetectable","2qxsB-2xymA:18.83"],["2VE3_A_REAA1445_1","PUTATIVE CYTOCHROME P450 120","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"PHE A 526;TRP A 500;ALA A 494;ALA A 396;THR A 399","None","0.99A","2ve3A-2xymA:undetectable","2ve3A-2xymA:21.34"],["2VE3_B_REAB1445_1","PUTATIVE CYTOCHROME P450 120","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"PHE A 526;TRP A 500;ALA A 494;ALA A 396;THR A 399","None","0.96A","2ve3B-2xymA:undetectable","2ve3B-2xymA:21.34"],["2XFH_A_CL6A1413_1","ERYTHROMYCIN B\/D C-12 HYDROXYLASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"ALA A 393;ALA A 396;THR A 399;PHE A 429","None","0.88A","2xfhA-2xymA:undetectable","2xfhA-2xymA:23.10"],["2ZUJ_A_CAMA422_0","CAMPHOR 5-MONOOXYGENASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"LEU A 384;VAL A 370;VAL A 321;LEU A 314","None","0.79A","2zujA-2xymA:undetectable","2zujA-2xymA:22.08"],["3CYX_A_ROCA201_2","HIV-1 PROTEASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",3,"ARG A 158;VAL A 284;THR A 287","None","0.72A","3cyxA-2xymA:undetectable","3cyxA-2xymA:10.62"],["3P4W_C_DSFC320_1","GLR4197 PROTEIN","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"ILE A 462;ILE A 463;VAL A 454;ILE A 412","None","0.87A","3p4wC-2xymA:undetectable","3p4wC-2xymA:21.62"],["3Q5P_A_TACA7101_1","MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"VAL A 284;ILE A 178;TYR A 240;GLU A 236;ILE A 233","None","1.33A","3q5pA-2xymA:undetectable","3q5pA-2xymA:19.42"],["3TNE_B_RITB401_2","SECRETED ASPARTIC PROTEASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"SER A 190;TYR A 296;VAL A  67;TYR A 219","None","1.06A","3tneB-2xymA:undetectable","3tneB-2xymA:20.98"],["3TWP_A_SALA404_1","ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"ALA A 416;PRO A 417;ARG A 381;ALA A 198","None","1.15A","3twpA-2xymA:undetectable","3twpA-2xymA:21.15"],["3WDM_B_ADNB301_1","4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A 519;ARG A 523;GLY A 522;LEU A 439;LEU A 525","None","1.09A","3wdmB-2xymA:undetectable","3wdmB-2xymA:20.00"],["3WDM_D_ADND301_1","4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A 519;ARG A 523;GLY A 522;LEU A 439;LEU A 525","None","1.12A","3wdmD-2xymA:undetectable","3wdmD-2xymA:20.00"],["4J24_B_ESTB600_1","ESTROGEN RECEPTOR BETA","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"LEU A 409;LEU A 425;MET A 426;ILE A 462;ILE A 463","None","0.96A","4j24B-2xymA:undetectable","4j24B-2xymA:18.21"],["4QVL_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.28A","4qvlV-2xymA:undetectable;4qvlb-2xymA:undetectable","4qvlV-2xymA:17.74;4qvlb-2xymA:14.88"],["4QVL_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.27A","4qvlH-2xymA:undetectable;4qvlN-2xymA:undetectable","4qvlH-2xymA:17.74;4qvlN-2xymA:14.88"],["4QVM_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.29A","4qvmV-2xymA:undetectable;4qvmb-2xymA:undetectable","4qvmV-2xymA:17.74;4qvmb-2xymA:14.88"],["4QVM_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.29A","4qvmH-2xymA:undetectable;4qvmN-2xymA:undetectable","4qvmH-2xymA:17.74;4qvmN-2xymA:14.88"],["4QVP_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.29A","4qvpV-2xymA:undetectable;4qvpb-2xymA:undetectable","4qvpV-2xymA:17.74;4qvpb-2xymA:14.88"],["4QVP_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.29A","4qvpH-2xymA:undetectable;4qvpN-2xymA:undetectable","4qvpH-2xymA:17.74;4qvpN-2xymA:14.88"],["4QVQ_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.29A","4qvqV-2xymA:undetectable;4qvqb-2xymA:undetectable","4qvqV-2xymA:17.74;4qvqb-2xymA:14.88"],["4QVQ_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.29A","4qvqH-2xymA:undetectable;4qvqN-2xymA:undetectable","4qvqH-2xymA:17.74;4qvqN-2xymA:14.88"],["4QVW_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.28A","4qvwV-2xymA:undetectable;4qvwb-2xymA:undetectable","4qvwV-2xymA:17.74;4qvwb-2xymA:14.88"],["4QVW_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.28A","4qvwH-2xymA:undetectable;4qvwN-2xymA:undetectable","4qvwH-2xymA:17.74;4qvwN-2xymA:14.88"],["4QW0_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.29A","4qw0V-2xymA:undetectable;4qw0b-2xymA:undetectable","4qw0V-2xymA:17.74;4qw0b-2xymA:14.88"],["4QW0_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.28A","4qw0H-2xymA:undetectable;4qw0N-2xymA:undetectable","4qw0H-2xymA:17.74;4qw0N-2xymA:14.88"],["4QW1_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.28A","4qw1V-2xymA:undetectable;4qw1b-2xymA:undetectable","4qw1V-2xymA:17.74;4qw1b-2xymA:14.88"],["4QW1_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.28A","4qw1H-2xymA:undetectable;4qw1N-2xymA:undetectable","4qw1H-2xymA:17.74;4qw1N-2xymA:14.88"],["4QW3_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.29A","4qw3V-2xymA:undetectable;4qw3b-2xymA:undetectable","4qw3V-2xymA:17.74;4qw3b-2xymA:14.88"],["4QW3_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.29A","4qw3H-2xymA:undetectable;4qw3N-2xymA:undetectable","4qw3H-2xymA:17.74;4qw3N-2xymA:14.88"],["4XI3_A_29SA601_1","ESTROGEN RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ALA A 395;LEU A 392;TRP A 420;MET A 426;PRO A 388","None","1.31A","4xi3A-2xymA:undetectable","4xi3A-2xymA:18.12"],["5BXN_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.27A","5bxnV-2xymA:undetectable;5bxnb-2xymA:undetectable","5bxnV-2xymA:17.74;5bxnb-2xymA:14.88"],["5BXN_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.27A","5bxnH-2xymA:undetectable;5bxnN-2xymA:undetectable","5bxnH-2xymA:17.74;5bxnN-2xymA:14.88"],["5CZ7_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.27A","5cz7H-2xymA:undetectable;5cz7N-2xymA:undetectable","5cz7H-2xymA:17.74;5cz7N-2xymA:14.88"],["5D0X_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.28A","5d0xV-2xymA:undetectable;5d0xb-2xymA:undetectable","5d0xV-2xymA:17.74;5d0xb-2xymA:14.88"],["5D0X_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.28A","5d0xH-2xymA:undetectable;5d0xN-2xymA:undetectable","5d0xH-2xymA:17.74;5d0xN-2xymA:14.88"],["5JCN_B_ASCB502_0","OS09G0567300 PROTEIN","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"GLU A 236;GLY A 290;ARG A 280;PHE A 224","None","1.10A","5jcnB-2xymA:undetectable","5jcnB-2xymA:21.43"],["5L5Z_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.28A","5l5zV-2xymA:undetectable;5l5zb-2xymA:undetectable","5l5zV-2xymA:17.74;5l5zb-2xymA:14.88"],["5L5Z_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.28A","5l5zH-2xymA:undetectable;5l5zN-2xymA:undetectable","5l5zH-2xymA:17.74;5l5zN-2xymA:14.88"],["5L66_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.27A","5l66V-2xymA:undetectable;5l66b-2xymA:undetectable","5l66V-2xymA:17.74;5l66b-2xymA:14.88"],["5L66_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.27A","5l66H-2xymA:undetectable;5l66N-2xymA:undetectable","5l66H-2xymA:17.74;5l66N-2xymA:14.88"],["5LF3_B_BO2B305_1","PROTEASOME SUBUNIT BETA TYPE-6","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.33A","5lf3b-2xymA:undetectable","5lf3b-2xymA:19.68"],["5LF3_N_BO2N304_1","PROTEASOME SUBUNIT BETA TYPE-6","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"THR A 136;THR A 137;GLY A 283;ALA A 281;THR A 287","None","1.32A","5lf3N-2xymA:undetectable","5lf3N-2xymA:19.68"],["5MWY_A_YNUA1101_0","MINERALOCORTICOID RECEPTOR","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"LEU A 285;LEU A 175;ALA A 252;TRP A 123;LEU A 245","None","1.21A","5mwyA-2xymA:undetectable","5mwyA-2xymA:19.86"],["6BRD_B_RFPB502_2","RIFAMPIN MONOOXYGENASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"GLN A 414;VAL A 454;LEU A 384;PRO A 417","None","1.07A","6brdB-2xymA:1.4","6brdB-2xymA:9.79"],["6HU9_T_PCFT101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"ASP A  61;TYR A 346;VAL A 297;SER A 190;ALA A 189","None","1.46A","6hu9L-2xymA:undetectable;6hu9P-2xymA:undetectable;6hu9T-2xymA:undetectable","6hu9L-2xymA:22.70;6hu9P-2xymA:15.62;6hu9T-2xymA:7.47"],["7DFR_A_FOLA161_1","DIHYDROFOLATE REDUCTASE","2xym","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",3,"ASP A 359;LEU A 362;ARG A 484","None","0.79A","7dfrA-2xymA:undetectable","7dfrA-2xymA:13.24"]]