SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xz4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		5 / 11 MET A 104
GLY A 142
SER A 154
ASN A 123
ILE A 140
 None
 1.28A 1odiB-2xz4A:
undetectable		 1odiB-2xz4A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		5 / 11 MET A 104
GLY A 142
SER A 154
ASN A 123
ILE A 140
 None
 1.26A 1odiC-2xz4A:
undetectable		 1odiC-2xz4A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		5 / 11 MET A 104
GLY A 142
SER A 154
ASN A 123
ILE A 140
 None
 1.33A 1odiE-2xz4A:
undetectable		 1odiE-2xz4A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		5 / 11 MET A 104
GLY A 142
SER A 154
ASN A 123
ILE A 140
 None
 1.33A 1odiF-2xz4A:
undetectable		 1odiF-2xz4A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		4 / 8 LEU A 199
ILE A  85
HIS A  87
GLY A 142
 None
None
EDO  A 601 (-3.9A)
None
 0.82A 3b9lA-2xz4A:
undetectable		 3b9lA-2xz4A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		4 / 6 TYR A 191
MET A 213
ILE A  86
HIS A 196
 None
None
None
EDO  A 601 (-4.5A)
 1.05A 3eteA-2xz4A:
undetectable
3eteE-2xz4A:
undetectable		 3eteA-2xz4A:
17.94
3eteE-2xz4A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		4 / 5 TYR A 191
MET A 213
ILE A  86
HIS A 196
 None
None
None
EDO  A 601 (-4.5A)
 1.07A 3eteB-2xz4A:
undetectable
3eteC-2xz4A:
undetectable		 3eteB-2xz4A:
17.94
3eteC-2xz4A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		3 / 3 GLU A  92
GLY A 159
THR A 160
 None
 0.58A 3iazA-2xz4A:
undetectable		 3iazA-2xz4A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		4 / 6 ILE A 120
GLY A 137
VAL A 153
HIS A 144
 None
 0.94A 4oltA-2xz4A:
undetectable		 4oltA-2xz4A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		4 / 6 ILE A 120
GLY A 137
VAL A 153
HIS A 144
 None
 1.02A 4oltB-2xz4A:
undetectable		 4oltB-2xz4A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		5 / 12 GLY A  67
ILE A 101
PHE A 124
TYR A 133
LEU A 125
 None
 1.00A 4pd4C-2xz4A:
undetectable		 4pd4C-2xz4A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		4 / 7 GLY A 142
GLN A 141
SER A 154
ASN A 123
 None
 0.93A 4ws0A-2xz4A:
undetectable		 4ws0A-2xz4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2xz4 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN LF
(Drosophila
melanogaster) 		4 / 8 GLY A 142
GLN A 141
SER A 154
ASN A 123
 None
 0.92A 4ws1A-2xz4A:
undetectable		 4ws1A-2xz4A:
19.33