SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y23'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_2
(PROTEIN (HIV-1
PROTEASE))		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 8 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.90A 1d4yB-2y23A:
undetectable		 1d4yB-2y23A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.80A 1hpvB-2y23A:
undetectable		 1hpvB-2y23A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.73A 1hxbB-2y23A:
undetectable		 1hxbB-2y23A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.80A 1hxwA-2y23A:
undetectable		 1hxwA-2y23A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.76A 1muiB-2y23A:
undetectable		 1muiB-2y23A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 10 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.80A 1sdtA-2y23A:
undetectable		 1sdtA-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.92A 1sduA-2y23A:
undetectable		 1sduA-2y23A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.81A 1t3rB-2y23A:
undetectable		 1t3rB-2y23A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2y23 MYOMESIN
(Homo
sapiens) 		4 / 8 PHE A1418
ASN A1373
GLU A1371
GLY A1370
 None
 1.05A 1ykiA-2y23A:
undetectable
1ykiB-2y23A:
undetectable		 1ykiA-2y23A:
23.35
1ykiB-2y23A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2y23 MYOMESIN
(Homo
sapiens) 		4 / 8 PHE A1418
ASN A1373
GLU A1371
GLY A1370
 None
 1.04A 1ykiA-2y23A:
undetectable
1ykiB-2y23A:
undetectable		 1ykiA-2y23A:
23.35
1ykiB-2y23A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2y23 MYOMESIN
(Homo
sapiens) 		4 / 8 PHE A1418
ASN A1373
GLU A1371
GLY A1370
 None
 1.02A 1ykiC-2y23A:
undetectable
1ykiD-2y23A:
undetectable		 1ykiC-2y23A:
23.35
1ykiD-2y23A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2y23 MYOMESIN
(Homo
sapiens) 		4 / 8 PHE A1418
ASN A1373
GLU A1371
GLY A1370
 None
 1.06A 1ykiC-2y23A:
undetectable
1ykiD-2y23A:
undetectable		 1ykiC-2y23A:
23.35
1ykiD-2y23A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2y23 MYOMESIN
(Homo
sapiens) 		4 / 5 ASP A1401
GLY A1409
VAL A1428
ILE A1389
 None
 0.75A 2aoiA-2y23A:
undetectable		 2aoiA-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 10 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.79A 2aquA-2y23A:
undetectable		 2aquA-2y23A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.76A 2aquB-2y23A:
undetectable		 2aquB-2y23A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.75A 2avoA-2y23A:
undetectable		 2avoA-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.78A 2avvA-2y23A:
undetectable		 2avvA-2y23A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.69A 2avvB-2y23A:
undetectable		 2avvB-2y23A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.79A 2avvE-2y23A:
undetectable		 2avvE-2y23A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.84A 2f80A-2y23A:
undetectable		 2f80A-2y23A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.75A 2f80B-2y23A:
undetectable		 2f80B-2y23A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.90A 2f81A-2y23A:
undetectable		 2f81A-2y23A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.74A 2fxeA-2y23A:
undetectable		 2fxeA-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.80A 2fxeB-2y23A:
undetectable		 2fxeB-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.81A 2hs1B-2y23A:
undetectable		 2hs1B-2y23A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.80A 2hs2B-2y23A:
undetectable		 2hs2B-2y23A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.90A 2ienA-2y23A:
undetectable		 2ienA-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ARG A1261
TYR A1277
HIS A1293
GLY A1299
ASN A1297
 None
 1.20A 2nyrB-2y23A:
undetectable		 2nyrB-2y23A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.81A 2o4kB-2y23A:
undetectable		 2o4kB-2y23A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.78A 2o4pB-2y23A:
undetectable		 2o4pB-2y23A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.84A 2o4sA-2y23A:
undetectable		 2o4sA-2y23A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.90A 2q5kA-2y23A:
undetectable		 2q5kA-2y23A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.80A 2q64B-2y23A:
undetectable		 2q64B-2y23A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.82A 2qakB-2y23A:
undetectable		 2qakB-2y23A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.85A 2qhcA-2y23A:
undetectable		 2qhcA-2y23A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.77A 2r5pD-2y23A:
undetectable		 2r5pD-2y23A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.79A 2r5qB-2y23A:
undetectable		 2r5qB-2y23A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.87A 2z54B-2y23A:
undetectable		 2z54B-2y23A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.76A 3cywB-2y23A:
undetectable		 3cywB-2y23A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.82A 3d1xB-2y23A:
undetectable		 3d1xB-2y23A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.82A 3d1yB-2y23A:
undetectable		 3d1yB-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.81A 3d1zA-2y23A:
undetectable		 3d1zA-2y23A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.75A 3d20B-2y23A:
undetectable		 3d20B-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.78A 3ekvB-2y23A:
undetectable		 3ekvB-2y23A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 10 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.84A 3ekyA-2y23A:
undetectable		 3ekyA-2y23A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.80A 3ekyB-2y23A:
undetectable		 3ekyB-2y23A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.86A 3el1B-2y23A:
undetectable		 3el1B-2y23A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.87A 3jvyA-2y23A:
undetectable		 3jvyA-2y23A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.73A 3jvyB-2y23A:
undetectable		 3jvyB-2y23A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.87A 3jw2A-2y23A:
undetectable		 3jw2A-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.78A 3jw2B-2y23A:
undetectable		 3jw2B-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.84A 3k4vB-2y23A:
undetectable		 3k4vB-2y23A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.85A 3lzuB-2y23A:
undetectable		 3lzuB-2y23A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.84A 3lzvB-2y23A:
undetectable		 3lzvB-2y23A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.87A 3ndtB-2y23A:
undetectable		 3ndtB-2y23A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.84A 3ndtC-2y23A:
undetectable		 3ndtC-2y23A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.84A 3ndtD-2y23A:
undetectable		 3ndtD-2y23A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.82A 3nduC-2y23A:
undetectable		 3nduC-2y23A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.73A 3ndwA-2y23A:
undetectable		 3ndwA-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.86A 3ndwB-2y23A:
undetectable		 3ndwB-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.77A 3ndxA-2y23A:
undetectable		 3ndxA-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.87A 3ndxB-2y23A:
undetectable		 3ndxB-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.88A 3nu4A-2y23A:
undetectable		 3nu4A-2y23A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 10 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.82A 3nu6A-2y23A:
undetectable		 3nu6A-2y23A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 10 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.82A 3nu6B-2y23A:
undetectable		 3nu6B-2y23A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		4 / 8 ASP A1401
GLY A1409
ILE A1410
VAL A1428
 None
 0.77A 3nu9A-2y23A:
undetectable		 3nu9A-2y23A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 10 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.85A 3nujA-2y23A:
undetectable		 3nujA-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 9 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.87A 3nuoA-2y23A:
undetectable		 3nuoA-2y23A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.82A 3oy4A-2y23A:
undetectable		 3oy4A-2y23A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.83A 3pwmA-2y23A:
undetectable		 3pwmA-2y23A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.84A 3pwmB-2y23A:
undetectable		 3pwmB-2y23A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.85A 3pwrB-2y23A:
undetectable		 3pwrB-2y23A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.78A 3tkgA-2y23A:
undetectable		 3tkgA-2y23A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.81A 3tkgB-2y23A:
undetectable		 3tkgB-2y23A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.78A 3tkgC-2y23A:
undetectable		 3tkgC-2y23A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.75A 3tkwB-2y23A:
undetectable		 3tkwB-2y23A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.84A 3tl9A-2y23A:
undetectable		 3tl9A-2y23A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		4 / 7 ASP A1401
GLY A1409
ILE A1410
VAL A1428
 None
 0.82A 3ufnB-2y23A:
undetectable		 3ufnB-2y23A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.83A 4dqbA-2y23A:
undetectable		 4dqbA-2y23A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 10 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.78A 4dqcA-2y23A:
undetectable		 4dqcA-2y23A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.79A 4dqeA-2y23A:
undetectable		 4dqeA-2y23A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.88A 4dqfA-2y23A:
undetectable		 4dqfA-2y23A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 10 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.85A 4dqfB-2y23A:
undetectable		 4dqfB-2y23A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 11 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.80A 4dqhA-2y23A:
undetectable		 4dqhA-2y23A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.71A 4jecA-2y23A:
undetectable		 4jecA-2y23A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 10 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.79A 4q1wB-2y23A:
undetectable		 4q1wB-2y23A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.78A 4q1xB-2y23A:
undetectable		 4q1xB-2y23A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.87A 4q1yB-2y23A:
undetectable		 4q1yB-2y23A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2y23 MYOMESIN
(Homo
sapiens) 		3 / 3 PHE A1318
ILE A1301
ASP A1322
 None
 0.65A 5cswA-2y23A:
undetectable		 5cswA-2y23A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2y23 MYOMESIN
(Homo
sapiens) 		3 / 3 PHE A1318
ILE A1301
ASP A1322
 None
 0.70A 5cswB-2y23A:
1.7		 5cswB-2y23A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2y23 MYOMESIN
(Homo
sapiens) 		3 / 3 ASP A1322
ASN A1327
PHE A1318
 None
 0.74A 5dsgB-2y23A:
undetectable		 5dsgB-2y23A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 12 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.80A 6difB-2y23A:
undetectable		 6difB-2y23A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 2y23 MYOMESIN
(Homo
sapiens) 		5 / 10 ASP A1401
GLY A1409
ILE A1410
VAL A1428
ILE A1389
 None
 0.80A 6dj2A-2y23A:
undetectable		 6dj2A-2y23A:
13.87