SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y38'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		5 / 8 PHE A 193
ILE A 235
PHE A 268
LEU A 177
VAL A 237
 None
 1.45A 1fslA-2y38A:
undetectable		 1fslA-2y38A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE509_0
(NAD-DEPENDENT
DEACETYLASE 2)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		4 / 6 ASP A 298
GLU A 234
ARG A 171
LYS A 165
 None
 1.45A 1yc2A-2y38A:
0.0
1yc2B-2y38A:
0.0
1yc2E-2y38A:
0.0		 1yc2A-2y38A:
19.91
1yc2B-2y38A:
19.91
1yc2E-2y38A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		3 / 3 ASN A 359
TYR A 251
SER A  49
 None
NAG  A3001 (-3.8A)
None
 0.94A 2gvcB-2y38A:
undetectable		 2gvcB-2y38A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		3 / 3 ASN A 359
TYR A 251
SER A  49
 None
NAG  A3001 (-3.8A)
None
 0.90A 2gvcE-2y38A:
undetectable		 2gvcE-2y38A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		4 / 5 LEU A 201
GLY A 205
ILE A 219
VAL A 218
 None
 0.73A 3wriA-2y38A:
undetectable		 3wriA-2y38A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		4 / 5 LEU A 201
GLY A 205
ILE A 219
VAL A 218
 None
 0.71A 3wriB-2y38A:
undetectable		 3wriB-2y38A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		4 / 5 LEU A 201
GLY A 205
ILE A 219
VAL A 218
 None
 0.75A 3wrkA-2y38A:
undetectable		 3wrkA-2y38A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		3 / 3 ARG A 304
HIS A  51
TYR A  54
 PO4  A4001 (-3.1A)
PO4  A4001 (-4.1A)
None
 1.26A 4fu8A-2y38A:
undetectable		 4fu8A-2y38A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		3 / 3 ARG A 304
HIS A  51
TYR A  54
 PO4  A4001 (-3.1A)
PO4  A4001 (-4.1A)
None
 1.32A 4fu9A-2y38A:
undetectable		 4fu9A-2y38A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		4 / 6 ARG A 265
ASP A 199
GLY A 205
PRO A 189
 NAG  A2001 (-3.8A)
None
None
None
 1.10A 4l1aB-2y38A:
undetectable		 4l1aB-2y38A:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		4 / 8 LEU A 325
PHE A  55
GLY A 303
LEU A 153
 None
 0.86A 5eseA-2y38A:
undetectable		 5eseA-2y38A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		3 / 3 ASP A 356
SER A 250
TYR A 251
 None
None
NAG  A3001 (-3.8A)
 0.88A 5glmA-2y38A:
undetectable		 5glmA-2y38A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2y38 LAMININ SUBUNIT
ALPHA-5
(Mus
musculus) 		3 / 3 ARG A 270
LEU A 174
PHE A 192
 None
 0.61A 6nknP-2y38A:
undetectable		 6nknP-2y38A:
19.70