SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y3m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2y3m PROTEIN TRANSPORT
PROTEIN HOFQ
(Aggregatibacter
actinomycetemcom
itans) 		4 / 6 PHE A  98
PRO A  29
VAL A  30
THR A 148
 None
 1.15A 5t7bA-2y3mA:
undetectable		 5t7bA-2y3mA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 2y3m PROTEIN TRANSPORT
PROTEIN HOFQ
(Aggregatibacter
actinomycetemcom
itans) 		4 / 4 PHE A  31
LEU A 185
LEU A 155
VAL A 143
 None
 1.35A 5xxiA-2y3mA:
undetectable		 5xxiA-2y3mA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 2y3m PROTEIN TRANSPORT
PROTEIN HOFQ
(Aggregatibacter
actinomycetemcom
itans) 		4 / 7 THR A 132
LEU A 171
ILE A 161
THR A 162
 None
 0.97A 5zsfA-2y3mA:
undetectable
5zsfB-2y3mA:
undetectable		 5zsfA-2y3mA:
20.13
5zsfB-2y3mA:
20.13