SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y69'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 4 THR J  27
LEU J  31
VAL J  34
LEU J  38
None
0.64A 1fbmB-2y69J:
3.0
1fbmB-2y69J:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 4 THR J  27
LEU J  31
VAL J  34
LEU J  38
None
0.37A 1fbmD-2y69J:
undetectable
1fbmD-2y69J:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 5 THR J  27
LEU J  31
VAL J  34
LEU J  38
None
0.50A 1fbmE-2y69J:
2.6
1fbmE-2y69J:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)
2y69 CYTOCHROME C OXIDASE
SUBUNIT 4 ISOFORM 1
CYTOCHROME C OXIDASE
SUBUNIT 5A

(Bos
taurus)
5 / 12 GLU E 103
LEU D  40
PHE E  61
LEU D  59
GLY E 105
None
1.09A 1jffB-2y69E:
undetectable
1jffB-2y69E:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 4 THR J  27
LEU J  31
VAL J  34
LEU J  38
None
0.78A 1mz9D-2y69J:
3.1
1mz9D-2y69J:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.42A 1v54A-2y69J:
undetectable
1v54J-2y69J:
8.0
1v54A-2y69J:
10.31
1v54J-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.55A 1v54N-2y69J:
undetectable
1v54W-2y69J:
8.0
1v54N-2y69J:
10.31
1v54W-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.52A 1v55A-2y69J:
undetectable
1v55J-2y69J:
8.0
1v55A-2y69J:
10.31
1v55J-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.42A 1v55N-2y69J:
undetectable
1v55W-2y69J:
8.0
1v55N-2y69J:
10.31
1v55W-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.35A 2dyrA-2y69J:
undetectable
2dyrJ-2y69J:
8.0
2dyrA-2y69J:
10.31
2dyrJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.29A 2dyrN-2y69J:
undetectable
2dyrW-2y69J:
8.0
2dyrN-2y69J:
10.31
2dyrW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.32A 2dysA-2y69J:
undetectable
2dysJ-2y69J:
7.9
2dysA-2y69J:
10.31
2dysJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.45A 2dysN-2y69J:
undetectable
2dysW-2y69J:
7.9
2dysN-2y69J:
10.31
2dysW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.41A 2eijA-2y69J:
undetectable
2eijJ-2y69J:
7.9
2eijA-2y69J:
10.31
2eijJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 8 TYR J  32
ARG J  33
MET J  36
LEU J  40
None
0.57A 2eijN-2y69J:
undetectable
2eijW-2y69J:
8.0
2eijN-2y69J:
10.31
2eijW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 8 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.00A 2eijN-2y69J:
undetectable
2eijW-2y69J:
8.0
2eijN-2y69J:
10.31
2eijW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.40A 2eikA-2y69J:
undetectable
2eikJ-2y69J:
8.0
2eikA-2y69J:
10.31
2eikJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.48A 2eikN-2y69J:
undetectable
2eikW-2y69J:
8.0
2eikN-2y69J:
10.31
2eikW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.45A 2eilA-2y69J:
undetectable
2eilJ-2y69J:
7.9
2eilA-2y69J:
10.31
2eilJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.46A 2eilN-2y69J:
undetectable
2eilW-2y69J:
8.0
2eilN-2y69J:
10.31
2eilW-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.49A 2eimJ-2y69J:
7.9
2eimJ-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.44A 2eimW-2y69J:
7.8
2eimW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.46A 2einA-2y69J:
undetectable
2einJ-2y69J:
7.8
2einA-2y69J:
10.31
2einJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.33A 2einN-2y69J:
undetectable
2einW-2y69J:
7.8
2einN-2y69J:
10.31
2einW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)
2y69 CYTOCHROME C OXIDASE
SUBUNIT 4 ISOFORM 1
CYTOCHROME C OXIDASE
SUBUNIT 5A

(Bos
taurus)
5 / 12 GLU E 103
LEU D  40
PHE E  61
LEU D  59
GLY E 105
None
1.09A 2hxfB-2y69E:
undetectable
2hxfB-2y69E:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)
2y69 CYTOCHROME C OXIDASE
SUBUNIT 4 ISOFORM 1
CYTOCHROME C OXIDASE
SUBUNIT 5A

(Bos
taurus)
5 / 12 GLU E 103
LEU D  40
PHE E  61
LEU D  59
GLY E 105
None
1.09A 2hxhB-2y69E:
undetectable
2hxhB-2y69E:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)
2y69 CYTOCHROME C OXIDASE
SUBUNIT 4 ISOFORM 1
CYTOCHROME C OXIDASE
SUBUNIT 5A

(Bos
taurus)
5 / 12 GLU E 103
LEU D  40
PHE E  61
LEU D  59
GLY E 105
None
1.08A 2p4nB-2y69E:
undetectable
2p4nB-2y69E:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)
2y69 CYTOCHROME C OXIDASE
SUBUNIT 4 ISOFORM 1
CYTOCHROME C OXIDASE
SUBUNIT 5A

(Bos
taurus)
5 / 12 GLU E 103
LEU D  40
PHE E  61
LEU D  59
GLY E 105
None
1.09A 2wbeB-2y69E:
undetectable
2wbeB-2y69E:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.36A 2zxwA-2y69J:
undetectable
2zxwJ-2y69J:
8.0
2zxwA-2y69J:
10.31
2zxwJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
None
0.33A 2zxwN-2y69J:
undetectable
2zxwW-2y69J:
7.9
2zxwN-2y69J:
10.31
2zxwW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.70A 3abkA-2y69J:
undetectable
3abkJ-2y69J:
7.9
3abkA-2y69J:
10.31
3abkJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
None
0.31A 3abkN-2y69J:
undetectable
3abkW-2y69J:
7.8
3abkN-2y69J:
10.31
3abkW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.35A 3ablA-2y69J:
undetectable
3ablJ-2y69J:
8.1
3ablA-2y69J:
10.31
3ablJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.27A 3ablN-2y69J:
undetectable
3ablW-2y69J:
8.0
3ablN-2y69J:
10.31
3ablW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.21A 3abmA-2y69J:
undetectable
3abmJ-2y69J:
8.2
3abmA-2y69J:
10.31
3abmJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.49A 3abmN-2y69J:
undetectable
3abmW-2y69J:
8.0
3abmN-2y69J:
10.31
3abmW-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.40A 3ag1J-2y69J:
7.8
3ag1J-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.35A 3ag1N-2y69J:
undetectable
3ag1W-2y69J:
7.7
3ag1N-2y69J:
10.31
3ag1W-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.47A 3ag2J-2y69J:
8.0
3ag2J-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
None
0.73A 3ag2N-2y69J:
undetectable
3ag2W-2y69J:
7.9
3ag2N-2y69J:
10.31
3ag2W-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.50A 3ag3A-2y69J:
undetectable
3ag3J-2y69J:
8.0
3ag3A-2y69J:
10.31
3ag3J-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.37A 3ag3N-2y69J:
undetectable
3ag3W-2y69J:
7.9
3ag3N-2y69J:
10.31
3ag3W-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2

(Bos
taurus)
5 / 12 ARG G  14
ARG G  17
PHE G  18
PHE G  21
GLY G  22
CHD  G1085 (-3.9A)
CHD  G1085 (-4.4A)
CHD  G1085 ( 4.3A)
None
CHD  G1085 (-3.5A)
0.00A 3ag4A-2y69G:
undetectable
3ag4B-2y69G:
undetectable
3ag4T-2y69G:
9.8
3ag4A-2y69G:
11.22
3ag4B-2y69G:
20.35
3ag4T-2y69G:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.24A 3ag4J-2y69J:
8.0
3ag4J-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
None
0.43A 3ag4N-2y69J:
undetectable
3ag4W-2y69J:
7.9
3ag4N-2y69J:
10.31
3ag4W-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.39A 3asnA-2y69J:
undetectable
3asnJ-2y69J:
8.0
3asnA-2y69J:
10.31
3asnJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.53A 3asnN-2y69J:
undetectable
3asnW-2y69J:
8.0
3asnN-2y69J:
10.31
3asnW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.34A 3asoA-2y69J:
undetectable
3asoJ-2y69J:
7.9
3asoA-2y69J:
10.31
3asoJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.51A 3asoN-2y69J:
undetectable
3asoW-2y69J:
7.9
3asoN-2y69J:
10.31
3asoW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)
2y69 CYTOCHROME C OXIDASE
SUBUNIT 4 ISOFORM 1
CYTOCHROME C OXIDASE
SUBUNIT 5A

(Bos
taurus)
5 / 12 GLU E 103
LEU D  40
PHE E  61
LEU D  59
GLY E 105
None
1.08A 3dcoB-2y69E:
undetectable
3dcoB-2y69E:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)
2y69 CYTOCHROME C OXIDASE
SUBUNIT 4 ISOFORM 1
CYTOCHROME C OXIDASE
SUBUNIT 5A

(Bos
taurus)
5 / 12 GLU E 103
LEU D  40
PHE E  61
LEU D  59
GLY E 105
None
1.07A 3edlB-2y69E:
undetectable
3edlB-2y69E:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)
2y69 CYTOCHROME C OXIDASE
SUBUNIT 4 ISOFORM 1
CYTOCHROME C OXIDASE
SUBUNIT 5A

(Bos
taurus)
5 / 12 GLU E 103
LEU D  40
PHE E  61
LEU D  59
GLY E 105
None
1.06A 3iz0B-2y69E:
undetectable
3iz0B-2y69E:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.72A 3wg7N-2y69J:
undetectable
3wg7W-2y69J:
7.9
3wg7N-2y69J:
10.31
3wg7W-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 7 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.00A 5b1aA-2y69J:
undetectable
5b1aJ-2y69J:
7.9
5b1aA-2y69J:
10.31
5b1aJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 7 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.12A 5b1bA-2y69J:
undetectable
5b1bJ-2y69J:
7.9
5b1bA-2y69J:
10.31
5b1bJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.83A 5b1bN-2y69J:
undetectable
5b1bW-2y69J:
7.9
5b1bN-2y69J:
10.31
5b1bW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 7 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.15A 5b3sA-2y69J:
undetectable
5b3sJ-2y69J:
8.0
5b3sA-2y69J:
10.31
5b3sJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.66A 5b3sN-2y69J:
undetectable
5b3sW-2y69J:
7.9
5b3sN-2y69J:
10.31
5b3sW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.55A 5iy5A-2y69J:
undetectable
5iy5J-2y69J:
7.9
5iy5A-2y69J:
10.31
5iy5J-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.30A 5iy5N-2y69J:
undetectable
5iy5W-2y69J:
7.8
5iy5N-2y69J:
10.31
5iy5W-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
2y69 CYTOCHROME C OXIDASE
SUBUNIT 5A

(Bos
taurus)
5 / 12 ILE E  24
PHE E  19
ILE E  67
VAL E  70
ILE E  47
None
0.79A 5mueA-2y69E:
undetectable
5mueA-2y69E:
21.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.68A 5w97J-2y69J:
7.6
5w97J-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WAU_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 4 TYR J  32
ARG J  33
THR J  37
LEU J  40
None
0.53A 5wauj-2y69J:
7.8
5wauj-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.33A 5wauJ-2y69J:
7.8
5wauJ-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.62A 5x19J-2y69J:
7.8
5x19J-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.77A 5x1bJ-2y69J:
7.6
5x1bJ-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.35A 5x1bW-2y69J:
7.6
5x1bW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.34A 5x1fA-2y69J:
undetectable
5x1fJ-2y69J:
7.9
5x1fA-2y69J:
10.31
5x1fJ-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.48A 5x1fW-2y69J:
7.8
5x1fW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.75A 5xdqN-2y69J:
undetectable
5xdqW-2y69J:
8.0
5xdqN-2y69J:
10.31
5xdqW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.38A 5xdxA-2y69J:
undetectable
5xdxJ-2y69J:
8.0
5xdxA-2y69J:
10.31
5xdxJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 8 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.08A 5xdxN-2y69J:
undetectable
5xdxW-2y69J:
7.9
5xdxN-2y69J:
10.31
5xdxW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
2y69 CYTOCHROME C OXIDASE
SUBUNIT 4 ISOFORM 1
CYTOCHROME C OXIDASE
POLYPEPTIDE 7B

(Bos
taurus;
Bos
taurus)
4 / 7 PHE K  24
ALA K  19
GLY K  21
GLY D  83
None
0.71A 5ybbB-2y69K:
undetectable
5ybbB-2y69K:
8.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 5 TYR J  32
ARG J  33
MET J  36
LEU J  40
None
1.18A 5z86J-2y69J:
8.0
5z86J-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 5 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.11A 5z86J-2y69J:
8.0
5z86J-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 6 TYR J  32
ARG J  33
MET J  36
LEU J  40
None
0.71A 5z86N-2y69J:
undetectable
5z86W-2y69J:
8.0
5z86N-2y69J:
10.31
5z86W-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 6 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.11A 5z86N-2y69J:
undetectable
5z86W-2y69J:
8.0
5z86N-2y69J:
10.31
5z86W-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 8 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.00A 5zcoA-2y69J:
undetectable
5zcoJ-2y69J:
8.0
5zcoA-2y69J:
10.31
5zcoJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 6 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.62A 5zcoN-2y69J:
undetectable
5zcoW-2y69J:
8.0
5zcoN-2y69J:
10.31
5zcoW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 7 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.00A 5zcpA-2y69J:
undetectable
5zcpJ-2y69J:
7.9
5zcpA-2y69J:
10.31
5zcpJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 8 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.59A 5zcpN-2y69J:
undetectable
5zcpW-2y69J:
7.9
5zcpN-2y69J:
10.31
5zcpW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 7 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.00A 5zcqA-2y69J:
undetectable
5zcqJ-2y69J:
7.9
5zcqA-2y69J:
10.31
5zcqJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 8 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.06A 5zcqN-2y69J:
undetectable
5zcqW-2y69J:
7.9
5zcqN-2y69J:
10.31
5zcqW-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.42A 6nknJ-2y69J:
7.6
6nknJ-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 5 TYR J  32
ARG J  33
MET J  36
LEU J  40
None
1.12A 6nknW-2y69J:
7.5
6nknW-2y69J:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
4 / 5 TYR J  32
MET J  36
THR J  37
LEU J  40
None
0.49A 6nknW-2y69J:
7.5
6nknW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.41A 6nmfA-2y69J:
undetectable
6nmfJ-2y69J:
7.7
6nmfA-2y69J:
10.31
6nmfJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos
taurus)
5 / 7 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
None
0.48A 6nmpA-2y69J:
undetectable
6nmpJ-2y69J:
7.5
6nmpA-2y69J:
10.31
6nmpJ-2y69J:
100.00