SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y6i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLY A 537
GLY A 540
LEU A 550
ASP A 554
 None
 0.70A 1aegA-2y6iA:
undetectable		 1aegA-2y6iA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 10 ASN A 455
VAL A 453
TYR A 764
GLY A 454
LEU A 529
 PEG  A1797 ( 4.3A)
None
None
None
None
 1.02A 1fkoA-2y6iA:
2.4		 1fkoA-2y6iA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ILE A 225
PHE A 189
GLY A 175
MET A 183
TYR A 178
 None
 1.45A 1g60B-2y6iA:
undetectable		 1g60B-2y6iA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 VAL A 488
GLY A 487
TYR A 479
GLU A 407
 None
 1.04A 1jlfA-2y6iA:
2.5
1jlfB-2y6iA:
undetectable		 1jlfA-2y6iA:
20.82
1jlfB-2y6iA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.94A 1v7zA-2y6iA:
undetectable		 1v7zA-2y6iA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.94A 1v7zB-2y6iA:
undetectable		 1v7zB-2y6iA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.95A 1v7zC-2y6iA:
undetectable		 1v7zC-2y6iA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.97A 1v7zD-2y6iA:
undetectable		 1v7zD-2y6iA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.97A 1v7zE-2y6iA:
undetectable		 1v7zE-2y6iA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.95A 1v7zF-2y6iA:
undetectable		 1v7zF-2y6iA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		3 / 3 ASP A 340
TYR A 344
GLU A 381
 1PE  A1799 (-3.8A)
1PE  A1799 ( 4.1A)
None
 0.77A 1vm1A-2y6iA:
undetectable		 1vm1A-2y6iA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF209_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 10 GLU A 559
LEU A 534
GLN A 530
GLU A 524
SER A 564
 None
None
None
ZN  A1791 ( 4.4A)
None
 1.26A 1wrlE-2y6iA:
undetectable
1wrlF-2y6iA:
undetectable		 1wrlE-2y6iA:
7.97
1wrlF-2y6iA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		3 / 3 LEU A 617
PHE A 625
ARG A 573
 None
 0.76A 1xdkB-2y6iA:
undetectable		 1xdkB-2y6iA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		3 / 3 LEU A 617
PHE A 625
ARG A 573
 None
 0.76A 1xdkF-2y6iA:
undetectable		 1xdkF-2y6iA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		3 / 3 ASP A 388
TYR A 387
LYS A 348
 None
 0.98A 2othA-2y6iA:
undetectable		 2othA-2y6iA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.94A 3a6jA-2y6iA:
undetectable		 3a6jA-2y6iA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 7 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.92A 3a6jB-2y6iA:
undetectable		 3a6jB-2y6iA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.93A 3a6jC-2y6iA:
undetectable		 3a6jC-2y6iA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.95A 3a6jE-2y6iA:
undetectable		 3a6jE-2y6iA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 GLU A 555
HIS A 523
HIS A 527
GLU A 524
 ZN  A1791 (-2.1A)
ZN  A1791 (-3.3A)
ZN  A1791 (-3.3A)
ZN  A1791 ( 4.4A)
 0.92A 3a6jF-2y6iA:
undetectable		 3a6jF-2y6iA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 THR A 130
ILE A 167
THR A 188
ASN A 138
ILE A 139
 None
 1.15A 3ddyA-2y6iA:
undetectable		 3ddyA-2y6iA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 LEU A 720
GLY A 784
TRP A 755
LEU A 747
PHE A 782
 None
 1.49A 3h52C-2y6iA:
undetectable		 3h52C-2y6iA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 LEU A 720
VAL A 785
TRP A 755
LEU A 747
PHE A 782
 None
 1.46A 3h52C-2y6iA:
undetectable		 3h52C-2y6iA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 7 TYR A 439
PHE A 417
ASN A 419
GLY A 420
 None
 1.13A 3kmoB-2y6iA:
2.0		 3kmoB-2y6iA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		3 / 4 SER A 475
GLY A 373
GLU A 381
 None
 0.58A 3raeA-2y6iA:
4.0
3raeC-2y6iA:
undetectable		 3raeA-2y6iA:
22.15
3raeC-2y6iA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 5 GLU A 691
GLU A 695
TYR A 758
HIS A 684
 None
 1.49A 4a97J-2y6iA:
undetectable		 4a97J-2y6iA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		3 / 4 SER A 475
GLY A 373
GLU A 381
 None
 0.57A 4juoA-2y6iA:
4.0
4juoC-2y6iA:
undetectable		 4juoA-2y6iA:
22.15
4juoC-2y6iA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		3 / 3 TYR A 525
ARG A 443
SER A 442
 None
 1.01A 4khpI-2y6iA:
undetectable
4khpJ-2y6iA:
undetectable		 4khpI-2y6iA:
11.14
4khpJ-2y6iA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJG_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ASP A 239
THR A 235
ASN A 228
VAL A 265
GLN A 268
 None
 1.23A 4njgA-2y6iA:
0.0		 4njgA-2y6iA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJG_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ASP A 239
THR A 235
ASN A 228
VAL A 265
GLN A 268
 None
 1.26A 4njgB-2y6iA:
undetectable		 4njgB-2y6iA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ASP A 239
THR A 235
ASN A 228
VAL A 265
GLN A 268
 None
 1.46A 4njhA-2y6iA:
0.8		 4njhA-2y6iA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ASP A 239
THR A 235
ASN A 228
VAL A 265
GLN A 268
 None
 1.45A 4njhB-2y6iA:
0.8		 4njhB-2y6iA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJI_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ASP A 239
THR A 235
ASN A 228
VAL A 265
GLN A 268
 None
 1.43A 4njiA-2y6iA:
0.7		 4njiA-2y6iA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJI_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ASP A 239
THR A 235
ASN A 228
VAL A 265
GLN A 268
 None
 1.43A 4njiB-2y6iA:
0.8		 4njiB-2y6iA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJJ_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ASP A 239
THR A 235
ASN A 228
VAL A 265
GLN A 268
 None
 1.43A 4njjA-2y6iA:
0.8		 4njjA-2y6iA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJJ_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ASP A 239
THR A 235
ASN A 228
VAL A 265
GLN A 268
 None
 1.42A 4njjB-2y6iA:
0.8		 4njjB-2y6iA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ASP A 239
THR A 235
ASN A 228
VAL A 265
GLN A 268
 None
 1.48A 4njkA-2y6iA:
0.8		 4njkA-2y6iA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ASP A 239
THR A 235
ASN A 228
VAL A 265
GLN A 268
 None
 1.47A 4njkB-2y6iA:
0.8		 4njkB-2y6iA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 6 LEU A 325
LEU A 322
GLU A 321
ILE A 290
 None
 0.91A 4ww7A-2y6iA:
undetectable		 4ww7A-2y6iA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 TYR A 439
ASP A 418
ILE A 424
TYR A 714
 None
 1.03A 4xjeA-2y6iA:
undetectable		 4xjeA-2y6iA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 11 PHE A 625
ALA A 614
GLY A 610
LEU A 529
THR A 526
 None
 1.15A 4zmeA-2y6iA:
undetectable		 4zmeA-2y6iA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		4 / 8 ILE A 472
LEU A 468
TYR A 504
LEU A 411
 None
 1.01A 5ieoA-2y6iA:
undetectable		 5ieoA-2y6iA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 PHE A 157
SER A 154
GLY A 200
GLY A 196
ASP A 211
 None
 1.14A 5kpcB-2y6iA:
undetectable		 5kpcB-2y6iA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ILE A 343
GLY A 326
ALA A 366
ILE A 383
ALA A 379
 None
 0.93A 5n0tB-2y6iA:
undetectable		 5n0tB-2y6iA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 2y6i COLLAGENASE
(Hathewaya
histolytica) 		5 / 12 ALA A 700
THR A 725
THR A 746
LEU A 747
PHE A 782
 None
 1.09A 5ybbA-2y6iA:
undetectable		 5ybbA-2y6iA:
19.28