SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y7b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 2y7b ACTIN-BINDING
PROTEIN ANILLIN
(Homo
sapiens) 		5 / 12 VAL A1073
ILE A 992
ILE A1032
ILE A1042
ILE A1014
 None
None
None
EDO  A2000 ( 4.7A)
None
 1.30A 1r5lA-2y7bA:
undetectable		 1r5lA-2y7bA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2y7b ACTIN-BINDING
PROTEIN ANILLIN
(Homo
sapiens) 		5 / 10 GLY A 998
ALA A1001
GLY A1000
VAL A1073
HIS A1003
 None
 1.27A 4c5nD-2y7bA:
undetectable		 4c5nD-2y7bA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2y7b ACTIN-BINDING
PROTEIN ANILLIN
(Homo
sapiens) 		3 / 3 ASP A1096
ASN A1103
SER A1088
 None
 0.72A 4obwA-2y7bA:
undetectable		 4obwA-2y7bA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2y7b ACTIN-BINDING
PROTEIN ANILLIN
(Homo
sapiens) 		5 / 12 PHE A1056
ALA A1089
TYR A1016
ILE A 992
LEU A1034
 None
 1.19A 5ljbA-2y7bA:
undetectable		 5ljbA-2y7bA:
22.07