SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EA1_A_TPFA470_1 (CYTOCHROME P450 51-LIKE RV0764C)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 8	PHE B 422 MET B 384 PHE B 387 LEU B 398	None	1.27A	1ea1A-2y7cB: undetectable	1ea1A-2y7cB: 23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K74_A_9CRA463_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2y7c	GENE 0.3 PROTEIN (Escherichia virus T7)	5 / 12	ILE D 33 ALA D 36 ALA D 37 LEU D 85 LEU D 14	None	0.81A	1k74A-2y7cD: undetectable	1k74A-2y7cD: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MMK_A_H4BA1427_1 (PHENYLALANINE-4-HYDR OXYLASE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 12	VAL B 310 LEU B 355 PHE B 356 TYR B 405 TRP B 447	None	1.42A	1mmkA-2y7cB: undetectable	1mmkA-2y7cB: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QCA_A_FUAA221_1 (TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE)	2y7c	TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN (Escherichia coli)	4 / 7	SER A 296 PHE A 299 PHE A 290 LEU A 232	None	0.99A	1qcaA-2y7cA: undetectable	1qcaA-2y7cA: 19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_A_IMNA379_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 12	THR B 95 VAL B 107 TYR B 71 ILE B 97 LEU B 59	None	1.44A	1z9hA-2y7cB: undetectable	1z9hA-2y7cB: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_C_IMNC379_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 12	THR B 95 VAL B 107 TYR B 71 ILE B 97 LEU B 59	None	1.44A	1z9hC-2y7cB: undetectable	1z9hC-2y7cB: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ADM_A_SAMA500_0 (ADENINE-N6-DNA-METHY LTRANSFERASE TAQI)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 11	THR B 151 ALA B 175 GLU B 216 PRO B 268 PHE B 292	None	0.88A	2admA-2y7cB: 19.3	2admA-2y7cB: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ADM_B_SAMB500_0 (ADENINE-N6-DNA-METHY LTRANSFERASE TAQI)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 11	THR B 151 ALA B 175 GLU B 216 PRO B 268 PHE B 292	None	0.91A	2admB-2y7cB: 19.2	2admB-2y7cB: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DDW_A_PXLA1003_1 (PYRIDOXINE KINASE)	2y7c	TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN (Escherichia coli)	4 / 8	VAL A 263 VAL A 258 LEU A 306 TYR A 316	None	0.92A	2ddwA-2y7cA: undetectable	2ddwA-2y7cA: 20.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OKC_A_SAMA500_0 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	6 / 12	ILE B 156 ALA B 175 GLY B 177 ASN B 266 PRO B 268 PHE B 292	None	0.61A	2okcA-2y7cB: 42.6	2okcA-2y7cB: 37.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OKC_A_SAMA500_0 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	6 / 12	ILE B 156 ALA B 175 GLY B 177 GLY B 180 ASN B 266 PHE B 292	None	0.45A	2okcA-2y7cB: 42.6	2okcA-2y7cB: 37.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OKC_A_SAMA500_0 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 12	ILE B 159 ALA B 175 THR B 221 ASN B 266 PRO B 268	None	1.08A	2okcA-2y7cB: 42.6	2okcA-2y7cB: 37.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OKC_B_SAMB500_0 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	6 / 12	ILE B 156 ALA B 175 GLY B 177 ASN B 266 PRO B 268 PHE B 292	None	0.60A	2okcB-2y7cB: 42.3	2okcB-2y7cB: 37.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OKC_B_SAMB500_0 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	6 / 12	ILE B 156 ALA B 175 GLY B 177 GLY B 180 ASN B 266 PHE B 292	None	0.42A	2okcB-2y7cB: 42.3	2okcB-2y7cB: 37.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2y7c	TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN (Escherichia coli)	3 / 3	ASP A 77 HIS A 97 HIS A 95	None	0.70A	2xxgA-2y7cA: undetectable	2xxgA-2y7cA: 21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1339_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2y7c	TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN (Escherichia coli)	3 / 3	ASP A 77 HIS A 97 HIS A 95	None	0.71A	2xxgC-2y7cA: undetectable	2xxgC-2y7cA: 21.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2Y7H_B_SAMB530_0 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	8 / 12	ILE B 159 ALA B 175 ASN B 248 THR B 249 LEU B 250 ASN B 266 PRO B 268 PHE B 292	None	1.40A	2y7hB-2y7cB: 53.4	2y7hB-2y7cB: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2Y7H_B_SAMB530_0 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	8 / 12	THR B 151 ALA B 175 THR B 178 GLY B 180 THR B 249 LEU B 250 PRO B 267 PHE B 292	None	1.49A	2y7hB-2y7cB: 53.4	2y7hB-2y7cB: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2Y7H_B_SAMB530_0 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	12 / 12	THR B 151 ILE B 156 ALA B 175 GLY B 177 THR B 178 GLY B 180 ASN B 248 THR B 249 LEU B 250 ASN B 266 PRO B 268 PHE B 292	None	0.31A	2y7hB-2y7cB: 53.4	2y7hB-2y7cB: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2Y7H_C_SAMC530_0 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	8 / 12	ILE B 159 ALA B 175 THR B 249 LEU B 250 ASN B 266 PRO B 268 THR B 275 PHE B 292	None	1.46A	2y7hC-2y7cB: 53.5	2y7hC-2y7cB: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2Y7H_C_SAMC530_0 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	8 / 12	THR B 151 ALA B 175 THR B 178 GLY B 180 THR B 249 LEU B 250 PRO B 267 PHE B 292	None	1.49A	2y7hC-2y7cB: 53.5	2y7hC-2y7cB: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2Y7H_C_SAMC530_0 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	12 / 12	THR B 151 ILE B 156 ALA B 175 GLY B 177 THR B 178 GLY B 180 THR B 249 LEU B 250 ASN B 266 PRO B 268 THR B 275 PHE B 292	None	0.30A	2y7hC-2y7cB: 53.5	2y7hC-2y7cB: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZIF_A_SAMA298_0 (PUTATIVE MODIFICATION METHYLASE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	6 / 12	PHE B 181 GLY B 177 THR B 178 GLU B 216 LEU B 217 VAL B 218	None	1.15A	2zifA-2y7cB: 3.1	2zifA-2y7cB: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZIF_A_SAMA298_0 (PUTATIVE MODIFICATION METHYLASE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	6 / 12	PRO B 268 PHE B 181 GLY B 177 GLU B 216 LEU B 217 VAL B 218	None	1.29A	2zifA-2y7cB: 3.1	2zifA-2y7cB: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_B_2FAB500_2 (ADENOSYLHOMOCYSTEINA SE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 5	LEU B 163 GLN B 166 THR B 358 HIS B 335	None	1.25A	2zj0B-2y7cB: 3.9	2zj0B-2y7cB: 23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_C_2FAC500_2 (ADENOSYLHOMOCYSTEINA SE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 5	LEU B 163 GLN B 166 THR B 358 HIS B 335	None	1.32A	2zj0C-2y7cB: 3.1	2zj0C-2y7cB: 23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_H_SVRH511_3 (PHOSPHOLIPASE A2)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 7	VAL B 89 ILE B 244 GLY B 214 LEU B 257	None	0.85A	3bjwH-2y7cB: undetectable	3bjwH-2y7cB: 10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BXO_B_SAMB238_1 (N,N-DIMETHYLTRANSFER ASE)	2y7c	TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN GENE 0.3 PROTEIN (Escherichia coli; Escherichia virus T7)	3 / 3	TYR A 27 GLU D 62 ASP D 58	None	0.78A	3bxoB-2y7cA: undetectable	3bxoB-2y7cA: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_B_ADNB500_2 (ADENOSYLHOMOCYSTEINA SE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 5	LEU B 163 GLN B 166 THR B 358 HIS B 335	None	1.29A	3ce6B-2y7cB: 3.1	3ce6B-2y7cB: 23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWW_A_SFXA801_1 (TRANSPORTER)	2y7c	GENE 0.3 PROTEIN TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN (Escherichia coli; Escherichia virus T7)	5 / 12	GLY A 91 ILE A 49 ALA A 106 PHE A 107 ASP D 63	None	1.06A	3gwwA-2y7cA: undetectable	3gwwA-2y7cA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCR_A_CHDA424_0 (FERROCHELATASE, MITOCHONDRIAL)	2y7c	TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN (Escherichia coli)	4 / 8	LEU A 444 ARG A 451 SER A 412 GLY A 420	None	1.04A	3hcrA-2y7cA: undetectable	3hcrA-2y7cA: 21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCR_B_CHDB924_0 (FERROCHELATASE, MITOCHONDRIAL)	2y7c	TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN (Escherichia coli)	4 / 7	LEU A 444 ARG A 451 SER A 412 GLY A 420	None	1.03A	3hcrB-2y7cA: undetectable	3hcrB-2y7cA: 21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HY7_B_097B801_1 (A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 5)	2y7c	GENE 0.3 PROTEIN (Escherichia virus T7)	5 / 9	ASP D 92 HIS D 34 HIS D 30 ILE D 87 LEU D 85	None	1.15A	3hy7B-2y7cD: undetectable	3hy7B-2y7cD: 18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1101_1 (STRUCTURAL PROTEIN VP3)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	3 / 3	GLU B 42 ASP B 111 ASP B 114	None	0.73A	3jb2A-2y7cB: 5.8	3jb2A-2y7cB: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LCV_B_SAMB301_0 (SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 12	PHE B 181 ALA B 306 ILE B 262 LEU B 300 LEU B 355	None	1.38A	3lcvB-2y7cB: 7.9	3lcvB-2y7cB: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ONN_A_ACTA270_0 (PROTEIN SSM1)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 5	LEU B 257 ARG B 279 LEU B 215 PRO B 174	None	1.32A	3onnA-2y7cB: undetectable	3onnA-2y7cB: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXC_A_ROCA401_2 (PROTEASE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	3 / 3	ARG B 245 LEU B 215 THR B 299	None	0.64A	3oxcA-2y7cB: undetectable	3oxcA-2y7cB: 11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9V_B_DXCB1_0 (INVASIN IPAD)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN GENE 0.3 PROTEIN (Escherichia coli; Escherichia virus T7)	4 / 7	ILE D 23 LEU D 29 LEU D 89 SER B 286	None	0.91A	3r9vA-2y7cD: undetectable 3r9vB-2y7cD: undetectable	3r9vA-2y7cD: 19.22 3r9vB-2y7cD: 19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3REM_A_SALA301_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	2y7c	GENE 0.3 PROTEIN (Escherichia virus T7)	4 / 8	VAL D 6 TYR D 82 ILE D 81 GLN D 78	None	1.04A	3remA-2y7cD: 2.3	3remA-2y7cD: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3REM_B_SALB301_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	2y7c	GENE 0.3 PROTEIN (Escherichia virus T7)	4 / 8	VAL D 6 TYR D 82 ILE D 81 GLN D 78	None	1.05A	3remB-2y7cD: 2.3	3remB-2y7cD: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WSJ_A_MK1A201_2 (PROTEASE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 7	LEU B 155 ALA B 307 VAL B 171 ILE B 159	None	0.96A	3wsjB-2y7cB: undetectable	3wsjB-2y7cB: 11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_D_SAMD401_1 (METHYLTRANSFERASE NSUN4)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	3 / 3	ASP B 461 ARG B 456 ASP B 330	None	0.79A	4fp9D-2y7cB: 9.6	4fp9D-2y7cB: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FR0_A_SAMA401_0 (ARSENIC METHYLTRANSFERASE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 12	LEU B 290 ILE B 296 ASN B 266 VAL B 308 LEU B 355	None	0.86A	4fr0A-2y7cB: 9.8	4fr0A-2y7cB: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K8K_B_ADNB403_1 (SUGAR KINASE)	2y7c	GENE 0.3 PROTEIN TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli; Escherichia virus T7)	5 / 12	GLY B 318 GLY B 319 ASN D 39 ILE B 324 THR B 285	None	1.06A	4k8kB-2y7cB: 3.2	4k8kB-2y7cB: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KBE_A_ADNA401_1 (PROBABLE SUGAR KINASE PROTEIN)	2y7c	GENE 0.3 PROTEIN TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli; Escherichia virus T7)	5 / 12	GLY B 318 GLY B 319 ASN D 39 ILE B 324 THR B 285	None	1.06A	4kbeA-2y7cB: 3.2	4kbeA-2y7cB: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KMU_H_RFPH1401_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 12	ASP B 239 ARG B 245 LEU B 182 PRO B 258 ILE B 213	None	1.30A	4kmuH-2y7cB: 0.0	4kmuH-2y7cB: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LCA_B_ADNB401_1 (PROBABLE SUGAR KINASE PROTEIN)	2y7c	GENE 0.3 PROTEIN TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli; Escherichia virus T7)	5 / 12	GLY B 318 GLY B 319 ASN D 39 ILE B 324 THR B 285	None	1.05A	4lcaB-2y7cB: 2.9	4lcaB-2y7cB: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5R_A_IPHA905_0 (PROTEIN ARGONAUTE-2)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 6	ALA B 146 THR B 221 THR B 178 TYR B 149	None	1.49A	4w5rA-2y7cB: undetectable	4w5rA-2y7cB: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5T_A_IPHA905_0 (PROTEIN ARGONAUTE-2)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 6	ALA B 146 THR B 221 THR B 178 TYR B 149	None	1.46A	4w5tA-2y7cB: undetectable	4w5tA-2y7cB: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4D_A_IPHA905_0 (PROTEIN ARGONAUTE-2)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 5	ALA B 146 THR B 221 THR B 178 TYR B 149	None	1.49A	4z4dA-2y7cB: 1.5	4z4dA-2y7cB: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4F_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 6	ALA B 146 THR B 221 THR B 178 TYR B 149	None	1.48A	4z4fA-2y7cB: undetectable	4z4fA-2y7cB: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4G_A_IPHA905_0 (PROTEIN ARGONAUTE-2)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 5	ALA B 146 THR B 221 THR B 178 TYR B 149	None	1.49A	4z4gA-2y7cB: undetectable	4z4gA-2y7cB: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4I_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 6	ALA B 146 THR B 221 THR B 178 TYR B 149	None	1.47A	4z4iA-2y7cB: undetectable	4z4iA-2y7cB: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_D_PAUD601_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN GENE 0.3 PROTEIN (Escherichia coli; Escherichia virus T7)	4 / 8	VAL D 41 TYR D 82 ALA D 40 GLY B 319	None	0.90A	5e26C-2y7cD: undetectable 5e26D-2y7cD: undetectable	5e26C-2y7cD: 15.34 5e26D-2y7cD: 15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FA8_A_SAMA301_1 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	3 / 3	THR B 151 ASP B 173 GLU B 216	None	0.78A	5fa8A-2y7cB: 11.5	5fa8A-2y7cB: 15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JGL_B_SAMB301_0 (UBIE/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 12	THR B 151 ALA B 175 GLY B 177 LEU B 217 LEU B 250	None	1.09A	5jglB-2y7cB: 11.2	5jglB-2y7cB: 21.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5YBB_A_SAMA601_0 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	5 / 12	ALA B 175 GLY B 177 THR B 178 GLY B 180 ASN B 266	None	0.92A	5ybbA-2y7cB: 30.6	5ybbA-2y7cB: 31.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5YBB_A_SAMA601_0 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	7 / 12	ALA B 175 GLY B 177 THR B 178 THR B 249 LEU B 250 ASN B 266 PHE B 292	None	0.65A	5ybbA-2y7cB: 30.6	5ybbA-2y7cB: 31.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5YBB_A_SAMA601_1 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 5	THR B 151 ASP B 173 GLU B 216 ASN B 248	None	0.72A	5ybbA-2y7cB: 30.5	5ybbA-2y7cB: 31.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5YBB_B_SAMB601_0 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	7 / 12	THR B 151 ASP B 173 THR B 178 LEU B 250 ASN B 266 PRO B 268 PHE B 292	None	0.75A	5ybbB-2y7cB: 30.6	5ybbB-2y7cB: 31.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5YBB_B_SAMB601_1 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 7	ALA B 175 GLY B 177 GLU B 216 THR B 249	None	0.52A	5ybbB-2y7cB: 30.6	5ybbB-2y7cB: 31.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5YBB_B_SAMB601_1 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 7	GLY B 177 GLU B 216 ASN B 248 THR B 249	None	0.56A	5ybbB-2y7cB: 30.6	5ybbB-2y7cB: 31.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YCP_A_BRLA501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2y7c	TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN (Escherichia coli)	3 / 3	GLY A 295 VAL A 351 MET A 347	None	0.64A	5ycpA-2y7cA: undetectable	5ycpA-2y7cA: 11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_B_9CRB501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2y7c	GENE 0.3 PROTEIN (Escherichia virus T7)	5 / 12	ILE D 33 ALA D 36 ALA D 37 LEU D 85 LEU D 14	None	0.82A	5z12B-2y7cD: undetectable	5z12B-2y7cD: 20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EU9_D_READ601_1 (RETINOIC ACID RECEPTOR)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	4 / 7	PHE B 401 LEU B 162 GLY B 411 LEU B 334	None	0.81A	6eu9D-2y7cB: undetectable	6eu9D-2y7cB: 10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA821_0 (GEPHYRIN)	2y7c	TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN (Escherichia coli)	3 / 3	ARG A 269 PHE A 270 GLY A 249	None	0.77A	6fgdA-2y7cA: undetectable	6fgdA-2y7cA: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NJ9_K_SAMK500_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	2y7c	TYPE I RESTRICTION ENZYME ECOKI M PROTEIN (Escherichia coli)	3 / 3	THR B 151 GLU B 216 ASN B 266	None	0.63A	6nj9K-2y7cB: 8.7	6nj9K-2y7cB: 21.08

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EA1_A_TPFA470_1","CYTOCHROME P450 51-LIKE RV0764C","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"PHE B 422;MET B 384;PHE B 387;LEU B 398","None","1.27A","1ea1A-2y7cB:undetectable","1ea1A-2y7cB:23.24"],["1K74_A_9CRA463_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2y7c","GENE 0.3 PROTEIN","Escherichia virus T7",5,"ILE D  33;ALA D  36;ALA D  37;LEU D  85;LEU D  14","None","0.81A","1k74A-2y7cD:undetectable","1k74A-2y7cD:19.33"],["1MMK_A_H4BA1427_1","PHENYLALANINE-4-HYDROXYLASE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"VAL B 310;LEU B 355;PHE B 356;TYR B 405;TRP B 447","None","1.42A","1mmkA-2y7cB:undetectable","1mmkA-2y7cB:19.63"],["1QCA_A_FUAA221_1","TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE","2y7c","TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN","Escherichia coli",4,"SER A 296;PHE A 299;PHE A 290;LEU A 232","None","0.99A","1qcaA-2y7cA:undetectable","1qcaA-2y7cA:19.60"],["1Z9H_A_IMNA379_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"THR B  95;VAL B 107;TYR B  71;ILE B  97;LEU B  59","None","1.44A","1z9hA-2y7cB:undetectable","1z9hA-2y7cB:17.72"],["1Z9H_C_IMNC379_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"THR B  95;VAL B 107;TYR B  71;ILE B  97;LEU B  59","None","1.44A","1z9hC-2y7cB:undetectable","1z9hC-2y7cB:17.72"],["2ADM_A_SAMA500_0","ADENINE-N6-DNA-METHYLTRANSFERASE TAQI","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"THR B 151;ALA B 175;GLU B 216;PRO B 268;PHE B 292","None","0.88A","2admA-2y7cB:19.3","2admA-2y7cB:21.79"],["2ADM_B_SAMB500_0","ADENINE-N6-DNA-METHYLTRANSFERASE TAQI","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"THR B 151;ALA B 175;GLU B 216;PRO B 268;PHE B 292","None","0.91A","2admB-2y7cB:19.2","2admB-2y7cB:21.79"],["2DDW_A_PXLA1003_1","PYRIDOXINE KINASE","2y7c","TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN","Escherichia coli",4,"VAL A 263;VAL A 258;LEU A 306;TYR A 316","None","0.92A","2ddwA-2y7cA:undetectable","2ddwA-2y7cA:20.70"],["2OKC_A_SAMA500_0","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",6,"ILE B 156;ALA B 175;GLY B 177;ASN B 266;PRO B 268;PHE B 292","None","0.61A","2okcA-2y7cB:42.6","2okcA-2y7cB:37.96"],["2OKC_A_SAMA500_0","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",6,"ILE B 156;ALA B 175;GLY B 177;GLY B 180;ASN B 266;PHE B 292","None","0.45A","2okcA-2y7cB:42.6","2okcA-2y7cB:37.96"],["2OKC_A_SAMA500_0","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"ILE B 159;ALA B 175;THR B 221;ASN B 266;PRO B 268","None","1.08A","2okcA-2y7cB:42.6","2okcA-2y7cB:37.96"],["2OKC_B_SAMB500_0","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",6,"ILE B 156;ALA B 175;GLY B 177;ASN B 266;PRO B 268;PHE B 292","None","0.60A","2okcB-2y7cB:42.3","2okcB-2y7cB:37.96"],["2OKC_B_SAMB500_0","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",6,"ILE B 156;ALA B 175;GLY B 177;GLY B 180;ASN B 266;PHE B 292","None","0.42A","2okcB-2y7cB:42.3","2okcB-2y7cB:37.96"],["2XXG_A_CUA1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2y7c","TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN","Escherichia coli",3,"ASP A  77;HIS A  97;HIS A  95","None","0.70A","2xxgA-2y7cA:undetectable","2xxgA-2y7cA:21.94"],["2XXG_C_CUC1339_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2y7c","TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN","Escherichia coli",3,"ASP A  77;HIS A  97;HIS A  95","None","0.71A","2xxgC-2y7cA:undetectable","2xxgC-2y7cA:21.94"],["2Y7H_B_SAMB530_0","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",8,"ILE B 159;ALA B 175;ASN B 248;THR B 249;LEU B 250;ASN B 266;PRO B 268;PHE B 292","None","1.40A","2y7hB-2y7cB:53.4","2y7hB-2y7cB:100.00"],["2Y7H_B_SAMB530_0","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",8,"THR B 151;ALA B 175;THR B 178;GLY B 180;THR B 249;LEU B 250;PRO B 267;PHE B 292","None","1.49A","2y7hB-2y7cB:53.4","2y7hB-2y7cB:100.00"],["2Y7H_B_SAMB530_0","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",12,"THR B 151;ILE B 156;ALA B 175;GLY B 177;THR B 178;GLY B 180;ASN B 248;THR B 249;LEU B 250;ASN B 266;PRO B 268;PHE B 292","None","0.31A","2y7hB-2y7cB:53.4","2y7hB-2y7cB:100.00"],["2Y7H_C_SAMC530_0","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",8,"ILE B 159;ALA B 175;THR B 249;LEU B 250;ASN B 266;PRO B 268;THR B 275;PHE B 292","None","1.46A","2y7hC-2y7cB:53.5","2y7hC-2y7cB:100.00"],["2Y7H_C_SAMC530_0","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",8,"THR B 151;ALA B 175;THR B 178;GLY B 180;THR B 249;LEU B 250;PRO B 267;PHE B 292","None","1.49A","2y7hC-2y7cB:53.5","2y7hC-2y7cB:100.00"],["2Y7H_C_SAMC530_0","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",12,"THR B 151;ILE B 156;ALA B 175;GLY B 177;THR B 178;GLY B 180;THR B 249;LEU B 250;ASN B 266;PRO B 268;THR B 275;PHE B 292","None","0.30A","2y7hC-2y7cB:53.5","2y7hC-2y7cB:100.00"],["2ZIF_A_SAMA298_0","PUTATIVE MODIFICATION METHYLASE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",6,"PHE B 181;GLY B 177;THR B 178;GLU B 216;LEU B 217;VAL B 218","None","1.15A","2zifA-2y7cB:3.1","2zifA-2y7cB:22.10"],["2ZIF_A_SAMA298_0","PUTATIVE MODIFICATION METHYLASE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",6,"PRO B 268;PHE B 181;GLY B 177;GLU B 216;LEU B 217;VAL B 218","None","1.29A","2zifA-2y7cB:3.1","2zifA-2y7cB:22.10"],["2ZJ0_B_2FAB500_2","ADENOSYLHOMOCYSTEINASE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"LEU B 163;GLN B 166;THR B 358;HIS B 335","None","1.25A","2zj0B-2y7cB:3.9","2zj0B-2y7cB:23.88"],["2ZJ0_C_2FAC500_2","ADENOSYLHOMOCYSTEINASE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"LEU B 163;GLN B 166;THR B 358;HIS B 335","None","1.32A","2zj0C-2y7cB:3.1","2zj0C-2y7cB:23.88"],["3BJW_H_SVRH511_3","PHOSPHOLIPASE A2","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"VAL B  89;ILE B 244;GLY B 214;LEU B 257","None","0.85A","3bjwH-2y7cB:undetectable","3bjwH-2y7cB:10.85"],["3BXO_B_SAMB238_1","N,N-DIMETHYLTRANSFERASE","2y7c","TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN;GENE 0.3 PROTEIN","Escherichia coli;Escherichia virus T7",3,"TYR A  27;GLU D  62;ASP D  58","None","0.78A","3bxoB-2y7cA:undetectable","3bxoB-2y7cA:20.43"],["3CE6_B_ADNB500_2","ADENOSYLHOMOCYSTEINASE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"LEU B 163;GLN B 166;THR B 358;HIS B 335","None","1.29A","3ce6B-2y7cB:3.1","3ce6B-2y7cB:23.71"],["3GWW_A_SFXA801_1","TRANSPORTER","2y7c","GENE 0.3 PROTEIN;TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN","Escherichia coli;Escherichia virus T7",5,"GLY A  91;ILE A  49;ALA A 106;PHE A 107;ASP D  63","None","1.06A","3gwwA-2y7cA:undetectable","3gwwA-2y7cA:21.48"],["3HCR_A_CHDA424_0","FERROCHELATASE, MITOCHONDRIAL","2y7c","TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN","Escherichia coli",4,"LEU A 444;ARG A 451;SER A 412;GLY A 420","None","1.04A","3hcrA-2y7cA:undetectable","3hcrA-2y7cA:21.94"],["3HCR_B_CHDB924_0","FERROCHELATASE, MITOCHONDRIAL","2y7c","TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN","Escherichia coli",4,"LEU A 444;ARG A 451;SER A 412;GLY A 420","None","1.03A","3hcrB-2y7cA:undetectable","3hcrB-2y7cA:21.94"],["3HY7_B_097B801_1","A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 5","2y7c","GENE 0.3 PROTEIN","Escherichia virus T7",5,"ASP D  92;HIS D  34;HIS D  30;ILE D  87;LEU D  85","None","1.15A","3hy7B-2y7cD:undetectable","3hy7B-2y7cD:18.10"],["3JB2_A_SAMA1101_1","STRUCTURAL PROTEIN VP3","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",3,"GLU B  42;ASP B 111;ASP B 114","None","0.73A","3jb2A-2y7cB:5.8","3jb2A-2y7cB:19.19"],["3LCV_B_SAMB301_0","SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"PHE B 181;ALA B 306;ILE B 262;LEU B 300;LEU B 355","None","1.38A","3lcvB-2y7cB:7.9","3lcvB-2y7cB:18.98"],["3ONN_A_ACTA270_0","PROTEIN SSM1","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"LEU B 257;ARG B 279;LEU B 215;PRO B 174","None","1.32A","3onnA-2y7cB:undetectable","3onnA-2y7cB:19.09"],["3OXC_A_ROCA401_2","PROTEASE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",3,"ARG B 245;LEU B 215;THR B 299","None","0.64A","3oxcA-2y7cB:undetectable","3oxcA-2y7cB:11.81"],["3R9V_B_DXCB1_0","INVASIN IPAD","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN;GENE 0.3 PROTEIN","Escherichia coli;Escherichia virus T7",4,"ILE D  23;LEU D  29;LEU D  89;SER B 286","None","0.91A","3r9vA-2y7cD:undetectable;3r9vB-2y7cD:undetectable","3r9vA-2y7cD:19.22;3r9vB-2y7cD:19.22"],["3REM_A_SALA301_1","SALICYLATE BIOSYNTHESIS PROTEIN PCHB","2y7c","GENE 0.3 PROTEIN","Escherichia virus T7",4,"VAL D   6;TYR D  82;ILE D  81;GLN D  78","None","1.04A","3remA-2y7cD:2.3","3remA-2y7cD:21.19"],["3REM_B_SALB301_1","SALICYLATE BIOSYNTHESIS PROTEIN PCHB","2y7c","GENE 0.3 PROTEIN","Escherichia virus T7",4,"VAL D   6;TYR D  82;ILE D  81;GLN D  78","None","1.05A","3remB-2y7cD:2.3","3remB-2y7cD:21.19"],["3WSJ_A_MK1A201_2","PROTEASE;PROTEASE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"LEU B 155;ALA B 307;VAL B 171;ILE B 159","None","0.96A","3wsjB-2y7cB:undetectable","3wsjB-2y7cB:11.70"],["4FP9_D_SAMD401_1","METHYLTRANSFERASE NSUN4","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",3,"ASP B 461;ARG B 456;ASP B 330","None","0.79A","4fp9D-2y7cB:9.6","4fp9D-2y7cB:22.10"],["4FR0_A_SAMA401_0","ARSENIC METHYLTRANSFERASE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"LEU B 290;ILE B 296;ASN B 266;VAL B 308;LEU B 355","None","0.86A","4fr0A-2y7cB:9.8","4fr0A-2y7cB:21.59"],["4K8K_B_ADNB403_1","SUGAR KINASE","2y7c","GENE 0.3 PROTEIN;TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli;Escherichia virus T7",5,"GLY B 318;GLY B 319;ASN D  39;ILE B 324;THR B 285","None","1.06A","4k8kB-2y7cB:3.2","4k8kB-2y7cB:19.85"],["4KBE_A_ADNA401_1","PROBABLE SUGAR KINASE PROTEIN","2y7c","GENE 0.3 PROTEIN;TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli;Escherichia virus T7",5,"GLY B 318;GLY B 319;ASN D  39;ILE B 324;THR B 285","None","1.06A","4kbeA-2y7cB:3.2","4kbeA-2y7cB:19.85"],["4KMU_H_RFPH1401_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"ASP B 239;ARG B 245;LEU B 182;PRO B 258;ILE B 213","None","1.30A","4kmuH-2y7cB:0.0","4kmuH-2y7cB:17.36"],["4LCA_B_ADNB401_1","PROBABLE SUGAR KINASE PROTEIN","2y7c","GENE 0.3 PROTEIN;TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli;Escherichia virus T7",5,"GLY B 318;GLY B 319;ASN D  39;ILE B 324;THR B 285","None","1.05A","4lcaB-2y7cB:2.9","4lcaB-2y7cB:19.85"],["4W5R_A_IPHA905_0","PROTEIN ARGONAUTE-2","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"ALA B 146;THR B 221;THR B 178;TYR B 149","None","1.49A","4w5rA-2y7cB:undetectable","4w5rA-2y7cB:19.56"],["4W5T_A_IPHA905_0","PROTEIN ARGONAUTE-2","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"ALA B 146;THR B 221;THR B 178;TYR B 149","None","1.46A","4w5tA-2y7cB:undetectable","4w5tA-2y7cB:19.56"],["4Z4D_A_IPHA905_0","PROTEIN ARGONAUTE-2","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"ALA B 146;THR B 221;THR B 178;TYR B 149","None","1.49A","4z4dA-2y7cB:1.5","4z4dA-2y7cB:19.56"],["4Z4F_A_IPHA904_0","PROTEIN ARGONAUTE-2","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"ALA B 146;THR B 221;THR B 178;TYR B 149","None","1.48A","4z4fA-2y7cB:undetectable","4z4fA-2y7cB:19.56"],["4Z4G_A_IPHA905_0","PROTEIN ARGONAUTE-2","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"ALA B 146;THR B 221;THR B 178;TYR B 149","None","1.49A","4z4gA-2y7cB:undetectable","4z4gA-2y7cB:19.56"],["4Z4I_A_IPHA904_0","PROTEIN ARGONAUTE-2","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"ALA B 146;THR B 221;THR B 178;TYR B 149","None","1.47A","4z4iA-2y7cB:undetectable","4z4iA-2y7cB:19.79"],["5E26_D_PAUD601_0","PANTOTHENATE KINASE 2, MITOCHONDRIAL","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN;GENE 0.3 PROTEIN","Escherichia coli;Escherichia virus T7",4,"VAL D  41;TYR D  82;ALA D  40;GLY B 319","None","0.90A","5e26C-2y7cD:undetectable;5e26D-2y7cD:undetectable","5e26C-2y7cD:15.34;5e26D-2y7cD:15.34"],["5FA8_A_SAMA301_1","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",3,"THR B 151;ASP B 173;GLU B 216","None","0.78A","5fa8A-2y7cB:11.5","5fa8A-2y7cB:15.34"],["5JGL_B_SAMB301_0","UBIE\/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"THR B 151;ALA B 175;GLY B 177;LEU B 217;LEU B 250","None","1.09A","5jglB-2y7cB:11.2","5jglB-2y7cB:21.33"],["5YBB_A_SAMA601_0","TYPE I RESTRICTION-MODIFICATION SYSTEM METHYLTRANSFERASE SUBUNIT","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",5,"ALA B 175;GLY B 177;THR B 178;GLY B 180;ASN B 266","None","0.92A","5ybbA-2y7cB:30.6","5ybbA-2y7cB:31.75"],["5YBB_A_SAMA601_0","TYPE I RESTRICTION-MODIFICATION SYSTEM METHYLTRANSFERASE SUBUNIT","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",7,"ALA B 175;GLY B 177;THR B 178;THR B 249;LEU B 250;ASN B 266;PHE B 292","None","0.65A","5ybbA-2y7cB:30.6","5ybbA-2y7cB:31.75"],["5YBB_A_SAMA601_1","TYPE I RESTRICTION-MODIFICATION SYSTEM METHYLTRANSFERASE SUBUNIT","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"THR B 151;ASP B 173;GLU B 216;ASN B 248","None","0.72A","5ybbA-2y7cB:30.5","5ybbA-2y7cB:31.75"],["5YBB_B_SAMB601_0","TYPE I RESTRICTION-MODIFICATION SYSTEM METHYLTRANSFERASE SUBUNIT","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",7,"THR B 151;ASP B 173;THR B 178;LEU B 250;ASN B 266;PRO B 268;PHE B 292","None","0.75A","5ybbB-2y7cB:30.6","5ybbB-2y7cB:31.75"],["5YBB_B_SAMB601_1","TYPE I RESTRICTION-MODIFICATION SYSTEM METHYLTRANSFERASE SUBUNIT","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"ALA B 175;GLY B 177;GLU B 216;THR B 249","None","0.52A","5ybbB-2y7cB:30.6","5ybbB-2y7cB:31.75"],["5YBB_B_SAMB601_1","TYPE I RESTRICTION-MODIFICATION SYSTEM METHYLTRANSFERASE SUBUNIT","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"GLY B 177;GLU B 216;ASN B 248;THR B 249","None","0.56A","5ybbB-2y7cB:30.6","5ybbB-2y7cB:31.75"],["5YCP_A_BRLA501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","2y7c","TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN","Escherichia coli",3,"GLY A 295;VAL A 351;MET A 347","None","0.64A","5ycpA-2y7cA:undetectable","5ycpA-2y7cA:11.73"],["5Z12_B_9CRB501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2y7c","GENE 0.3 PROTEIN","Escherichia virus T7",5,"ILE D  33;ALA D  36;ALA D  37;LEU D  85;LEU D  14","None","0.82A","5z12B-2y7cD:undetectable","5z12B-2y7cD:20.49"],["6EU9_D_READ601_1","RETINOIC ACID RECEPTOR","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",4,"PHE B 401;LEU B 162;GLY B 411;LEU B 334","None","0.81A","6eu9D-2y7cB:undetectable","6eu9D-2y7cB:10.55"],["6FGD_A_ACTA821_0","GEPHYRIN","2y7c","TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN","Escherichia coli",3,"ARG A 269;PHE A 270;GLY A 249","None","0.77A","6fgdA-2y7cA:undetectable","6fgdA-2y7cA:22.81"],["6NJ9_K_SAMK500_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","2y7c","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","Escherichia coli",3,"THR B 151;GLU B 216;ASN B 266","None","0.63A","6nj9K-2y7cB:8.7","6nj9K-2y7cB:21.08"]]