SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y7i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2y7i STM4351
(Salmonella
enterica) 		4 / 8 SER A  77
ARG A 213
GLY A  28
GLN A  69
 None
 0.97A 4af0A-2y7iA:
undetectable		 4af0A-2y7iA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 2y7i STM4351
(Salmonella
enterica) 		3 / 3 VAL A 174
TYR A 159
ALA A 162
 None
 0.57A 4ybnA-2y7iA:
undetectable		 4ybnA-2y7iA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 2y7i STM4351
(Salmonella
enterica) 		5 / 12 PRO A  35
HIS A 140
GLY A 176
ASP A  91
TYR A  36
 None
ARG  A1245 (-4.3A)
None
ARG  A1245 (-3.7A)
None
 1.32A 5eeiA-2y7iA:
undetectable		 5eeiA-2y7iA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 2y7i STM4351
(Salmonella
enterica) 		5 / 12 PRO A  35
HIS A 140
GLY A 176
ASP A  91
TYR A  36
 None
ARG  A1245 (-4.3A)
None
ARG  A1245 (-3.7A)
None
 1.31A 5eeiB-2y7iA:
undetectable		 5eeiB-2y7iA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 2y7i STM4351
(Salmonella
enterica) 		4 / 6 PHE A  66
PHE A  80
VAL A  86
ASP A  84
 None
None
None
ZN  A1247 (-2.2A)
 1.24A 5hesA-2y7iA:
undetectable		 5hesA-2y7iA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2y7i STM4351
(Salmonella
enterica) 		5 / 12 ASP A 177
ALA A 112
PHE A 175
GLY A 133
GLU A 135
 ARG  A1245 (-3.1A)
None
None
None
ARG  A1245 (-2.9A)
 1.21A 5hfjC-2y7iA:
undetectable		 5hfjC-2y7iA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 2y7i STM4351
(Salmonella
enterica) 		4 / 7 THR A 139
ASP A  91
TYR A  33
GLY A  89
 ARG  A1245 (-3.4A)
ARG  A1245 (-3.7A)
ARG  A1245 (-3.8A)
ARG  A1245 (-4.7A)
 1.01A 5hwaA-2y7iA:
undetectable		 5hwaA-2y7iA:
22.39