SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y8u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 9 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 1c9sA-2y8uA:
undetectable
1c9sB-2y8uA:
undetectable		 1c9sA-2y8uA:
14.60
1c9sB-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.21A 1c9sB-2y8uA:
undetectable
1c9sC-2y8uA:
undetectable		 1c9sB-2y8uA:
14.60
1c9sC-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.22A 1c9sG-2y8uA:
undetectable
1c9sH-2y8uA:
undetectable		 1c9sG-2y8uA:
14.60
1c9sH-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.97A 1c9sN-2y8uA:
undetectable
1c9sO-2y8uA:
undetectable		 1c9sN-2y8uA:
14.60
1c9sO-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.99A 1c9sP-2y8uA:
undetectable
1c9sQ-2y8uA:
undetectable		 1c9sP-2y8uA:
14.60
1c9sQ-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 9 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 1.01A 1c9sQ-2y8uA:
undetectable
1c9sR-2y8uA:
undetectable		 1c9sQ-2y8uA:
14.60
1c9sR-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.98A 1c9sL-2y8uA:
undetectable
1c9sV-2y8uA:
undetectable		 1c9sL-2y8uA:
14.60
1c9sV-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 LEU A 104
LEU A 107
GLY A 108
MET A 134
LEU A 146
 None
 1.09A 1gs4A-2y8uA:
undetectable		 1gs4A-2y8uA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.22A 1gtfC-2y8uA:
undetectable
1gtfD-2y8uA:
undetectable		 1gtfC-2y8uA:
14.60
1gtfD-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 9 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.95A 1gtfD-2y8uA:
undetectable
1gtfE-2y8uA:
undetectable		 1gtfD-2y8uA:
14.60
1gtfE-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 9 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 1gtfF-2y8uA:
undetectable
1gtfG-2y8uA:
undetectable		 1gtfF-2y8uA:
14.60
1gtfG-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.22A 1gtfG-2y8uA:
undetectable
1gtfH-2y8uA:
undetectable		 1gtfG-2y8uA:
14.60
1gtfH-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 1gtfH-2y8uA:
undetectable
1gtfI-2y8uA:
undetectable		 1gtfH-2y8uA:
14.60
1gtfI-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.97A 1gtfJ-2y8uA:
undetectable
1gtfK-2y8uA:
undetectable		 1gtfJ-2y8uA:
14.60
1gtfK-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.99A 1gtfQ-2y8uA:
undetectable
1gtfR-2y8uA:
undetectable		 1gtfQ-2y8uA:
14.60
1gtfR-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 9 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.98A 1gtfR-2y8uA:
undetectable
1gtfS-2y8uA:
undetectable		 1gtfR-2y8uA:
14.60
1gtfS-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.97A 1gtfS-2y8uA:
undetectable
1gtfT-2y8uA:
undetectable		 1gtfS-2y8uA:
14.60
1gtfT-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 GLY A  95
THR A 223
HIS A  92
THR A  69
ARG A  67
 None
 1.22A 1gtfU-2y8uA:
undetectable
1gtfV-2y8uA:
undetectable		 1gtfU-2y8uA:
14.60
1gtfV-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 1.01A 1gtnT-2y8uA:
undetectable
1gtnU-2y8uA:
undetectable		 1gtnT-2y8uA:
14.60
1gtnU-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.96A 1gtnL-2y8uA:
undetectable
1gtnV-2y8uA:
undetectable		 1gtnL-2y8uA:
14.60
1gtnV-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.98A 1utdE-2y8uA:
undetectable
1utdF-2y8uA:
undetectable		 1utdE-2y8uA:
14.60
1utdF-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.99A 1utdH-2y8uA:
undetectable
1utdI-2y8uA:
undetectable		 1utdH-2y8uA:
14.60
1utdI-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.95A 1utdL-2y8uA:
undetectable
1utdM-2y8uA:
undetectable		 1utdL-2y8uA:
14.60
1utdM-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 GLY A  95
THR A 223
HIS A  92
THR A  69
ARG A  67
 None
 1.19A 1utdM-2y8uA:
undetectable
1utdN-2y8uA:
undetectable		 1utdM-2y8uA:
14.60
1utdN-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.99A 1utdO-2y8uA:
undetectable
1utdP-2y8uA:
undetectable		 1utdO-2y8uA:
14.60
1utdP-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.96A 1utdP-2y8uA:
undetectable
1utdQ-2y8uA:
undetectable		 1utdP-2y8uA:
14.60
1utdQ-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 1.00A 1utdS-2y8uA:
undetectable
1utdT-2y8uA:
undetectable		 1utdS-2y8uA:
14.60
1utdT-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  95
THR A 223
HIS A  92
THR A  69
GLY A  91
 None
 0.97A 1utdU-2y8uA:
undetectable
1utdV-2y8uA:
undetectable		 1utdU-2y8uA:
14.60
1utdV-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.97A 1utdL-2y8uA:
undetectable
1utdV-2y8uA:
undetectable		 1utdL-2y8uA:
14.60
1utdV-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_1
(ADENOSYLHOMOCYSTEINA
SE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 LEU A  73
HIS A  97
THR A  98
ASP A  48
LEU A 139
 None
CO  A1239 ( 3.3A)
None
CO  A1239 ( 2.4A)
PO4  A1238 ( 4.8A)
 1.03A 1xwfA-2y8uA:
3.3		 1xwfA-2y8uA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_1
(ADENOSYLHOMOCYSTEINA
SE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 LEU A  73
HIS A  97
THR A  98
ASP A  48
LEU A 139
 None
CO  A1239 ( 3.3A)
None
CO  A1239 ( 2.4A)
PO4  A1238 ( 4.8A)
 1.05A 1xwfB-2y8uA:
undetectable		 1xwfB-2y8uA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_1
(ADENOSYLHOMOCYSTEINA
SE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 LEU A  73
HIS A  97
THR A  98
ASP A  48
LEU A 139
 None
CO  A1239 ( 3.3A)
None
CO  A1239 ( 2.4A)
PO4  A1238 ( 4.8A)
 1.04A 1xwfC-2y8uA:
undetectable		 1xwfC-2y8uA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_1
(ADENOSYLHOMOCYSTEINA
SE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 LEU A  73
HIS A  97
THR A  98
ASP A  48
LEU A 139
 None
CO  A1239 ( 3.3A)
None
CO  A1239 ( 2.4A)
PO4  A1238 ( 4.8A)
 1.05A 1xwfD-2y8uA:
3.2		 1xwfD-2y8uA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		4 / 5 ASP A  59
LEU A  58
MET A  87
ARG A  86
 None
 1.18A 2gj5A-2y8uA:
undetectable		 2gj5A-2y8uA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		3 / 3 LEU A 104
LEU A 107
ARG A 118
 None
 0.75A 3hcnB-2y8uA:
undetectable		 3hcnB-2y8uA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		4 / 7 ARG A  88
VAL A 129
TYR A 236
ILE A 233
 None
 1.01A 3hgxA-2y8uA:
undetectable		 3hgxA-2y8uA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		4 / 8 ARG A  88
VAL A 129
TYR A 236
ILE A 233
 None
 1.03A 3remA-2y8uA:
undetectable		 3remA-2y8uA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		4 / 8 ARG A  88
VAL A 129
TYR A 236
ILE A 233
 None
 1.02A 3remB-2y8uA:
undetectable		 3remB-2y8uA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 LEU A  73
HIS A  97
THR A  98
ASP A  48
HIS A 196
 None
CO  A1239 ( 3.3A)
None
CO  A1239 ( 2.4A)
PO4  A1238 (-4.1A)
 1.33A 4lvcB-2y8uA:
3.6		 4lvcB-2y8uA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.19A 5eeuD-2y8uA:
undetectable
5eeuE-2y8uA:
undetectable		 5eeuD-2y8uA:
14.60
5eeuE-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.21A 5eeuH-2y8uA:
undetectable
5eeuI-2y8uA:
undetectable		 5eeuH-2y8uA:
14.60
5eeuI-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5eeuJ-2y8uA:
undetectable
5eeuK-2y8uA:
undetectable		 5eeuJ-2y8uA:
14.60
5eeuK-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 9 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.21A 5eeuL-2y8uA:
undetectable
5eeuV-2y8uA:
undetectable		 5eeuL-2y8uA:
14.60
5eeuV-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.99A 5eevA-2y8uA:
undetectable
5eevB-2y8uA:
undetectable		 5eevA-2y8uA:
14.60
5eevB-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.19A 5eevD-2y8uA:
undetectable
5eevE-2y8uA:
undetectable		 5eevD-2y8uA:
14.60
5eevE-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5eevJ-2y8uA:
undetectable
5eevK-2y8uA:
undetectable		 5eevJ-2y8uA:
14.60
5eevK-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.99A 5eewA-2y8uA:
undetectable
5eewB-2y8uA:
undetectable		 5eewA-2y8uA:
14.60
5eewB-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.19A 5eewD-2y8uA:
undetectable
5eewE-2y8uA:
undetectable		 5eewD-2y8uA:
14.60
5eewE-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.21A 5eewH-2y8uA:
undetectable
5eewI-2y8uA:
undetectable		 5eewH-2y8uA:
14.60
5eewI-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5eewJ-2y8uA:
undetectable
5eewK-2y8uA:
undetectable		 5eewJ-2y8uA:
14.60
5eewK-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.99A 5eexA-2y8uA:
undetectable
5eexB-2y8uA:
undetectable		 5eexA-2y8uA:
14.60
5eexB-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.19A 5eexD-2y8uA:
undetectable
5eexE-2y8uA:
undetectable		 5eexD-2y8uA:
14.60
5eexE-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.21A 5eexH-2y8uA:
undetectable
5eexI-2y8uA:
undetectable		 5eexH-2y8uA:
14.60
5eexI-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5eexI-2y8uA:
undetectable
5eexJ-2y8uA:
undetectable		 5eexI-2y8uA:
14.60
5eexJ-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5eexJ-2y8uA:
undetectable
5eexK-2y8uA:
undetectable		 5eexJ-2y8uA:
14.60
5eexK-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 9 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.22A 5eexL-2y8uA:
undetectable
5eexV-2y8uA:
undetectable		 5eexL-2y8uA:
14.60
5eexV-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.99A 5eeyA-2y8uA:
undetectable
5eeyB-2y8uA:
undetectable		 5eeyA-2y8uA:
14.60
5eeyB-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.19A 5eeyD-2y8uA:
undetectable
5eeyE-2y8uA:
undetectable		 5eeyD-2y8uA:
14.60
5eeyE-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5eeyI-2y8uA:
undetectable
5eeyJ-2y8uA:
undetectable		 5eeyI-2y8uA:
14.60
5eeyJ-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.21A 5eeyJ-2y8uA:
undetectable
5eeyK-2y8uA:
undetectable		 5eeyJ-2y8uA:
14.60
5eeyK-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 9 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.22A 5eeyL-2y8uA:
undetectable
5eeyV-2y8uA:
undetectable		 5eeyL-2y8uA:
14.60
5eeyV-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.99A 5eezA-2y8uA:
undetectable
5eezB-2y8uA:
undetectable		 5eezA-2y8uA:
14.60
5eezB-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.19A 5eezD-2y8uA:
undetectable
5eezE-2y8uA:
undetectable		 5eezD-2y8uA:
14.60
5eezE-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5eezI-2y8uA:
undetectable
5eezJ-2y8uA:
undetectable		 5eezI-2y8uA:
14.60
5eezJ-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.99A 5ef0A-2y8uA:
undetectable
5ef0B-2y8uA:
undetectable		 5ef0A-2y8uA:
14.60
5ef0B-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.19A 5ef0D-2y8uA:
undetectable
5ef0E-2y8uA:
undetectable		 5ef0D-2y8uA:
14.60
5ef0E-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5ef0I-2y8uA:
undetectable
5ef0J-2y8uA:
undetectable		 5ef0I-2y8uA:
14.60
5ef0J-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 9 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.22A 5ef0L-2y8uA:
undetectable
5ef0V-2y8uA:
undetectable		 5ef0L-2y8uA:
14.60
5ef0V-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.99A 5ef1A-2y8uA:
undetectable
5ef1B-2y8uA:
undetectable		 5ef1A-2y8uA:
14.60
5ef1B-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.19A 5ef1D-2y8uA:
undetectable
5ef1E-2y8uA:
undetectable		 5ef1D-2y8uA:
14.60
5ef1E-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5ef1I-2y8uA:
undetectable
5ef1J-2y8uA:
undetectable		 5ef1I-2y8uA:
14.60
5ef1J-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.99A 5ef2A-2y8uA:
undetectable
5ef2B-2y8uA:
undetectable		 5ef2A-2y8uA:
14.60
5ef2B-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5ef2D-2y8uA:
undetectable
5ef2E-2y8uA:
undetectable		 5ef2D-2y8uA:
14.60
5ef2E-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5ef2I-2y8uA:
undetectable
5ef2J-2y8uA:
undetectable		 5ef2I-2y8uA:
14.60
5ef2J-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 GLY A  91
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 0.99A 5ef3A-2y8uA:
undetectable
5ef3B-2y8uA:
undetectable		 5ef3A-2y8uA:
14.60
5ef3B-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 10 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5ef3D-2y8uA:
undetectable
5ef3E-2y8uA:
undetectable		 5ef3D-2y8uA:
14.60
5ef3E-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 11 ARG A  67
GLY A  95
THR A 223
HIS A  92
THR A  69
 None
 1.20A 5ef3I-2y8uA:
undetectable
5ef3J-2y8uA:
undetectable		 5ef3I-2y8uA:
14.60
5ef3J-2y8uA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 ILE A  42
ALA A 221
PHE A 182
LEU A 211
GLY A 189
 None
 1.23A 5i71A-2y8uA:
undetectable		 5i71A-2y8uA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 12 ILE A  42
ALA A 221
PHE A 182
LEU A 211
GLY A 189
 None
 1.24A 5i75A-2y8uA:
undetectable		 5i75A-2y8uA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 6 ASP A  47
ASP A  48
HIS A  97
HIS A 101
HIS A 196
 PO4  A1238 (-3.9A)
CO  A1239 ( 2.4A)
CO  A1239 ( 3.3A)
CO  A1239 ( 3.2A)
PO4  A1238 (-4.1A)
 0.25A 5ncdA-2y8uA:
24.8
5ncdD-2y8uA:
25.2		 5ncdA-2y8uA:
26.21
5ncdD-2y8uA:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 6 ASP A  47
ASP A  48
HIS A  97
HIS A 101
HIS A 196
 PO4  A1238 (-3.9A)
CO  A1239 ( 2.4A)
CO  A1239 ( 3.3A)
CO  A1239 ( 3.2A)
PO4  A1238 (-4.1A)
 0.21A 5ncdB-2y8uA:
25.2
5ncdC-2y8uA:
25.1		 5ncdB-2y8uA:
26.21
5ncdC-2y8uA:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		4 / 4 ASP A  47
HIS A  97
HIS A 101
HIS A 196
 PO4  A1238 (-3.9A)
CO  A1239 ( 3.3A)
CO  A1239 ( 3.2A)
PO4  A1238 (-4.1A)
 0.19A 5ncdD-2y8uA:
25.2		 5ncdD-2y8uA:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		6 / 8 ASP A  47
ASP A  48
HIS A  97
HIS A 101
PRO A 137
HIS A 196
 PO4  A1238 (-3.9A)
CO  A1239 ( 2.4A)
CO  A1239 ( 3.3A)
CO  A1239 ( 3.2A)
None
PO4  A1238 (-4.1A)
 0.34A 5nekB-2y8uA:
25.2		 5nekB-2y8uA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 8 ASP A  47
ASP A  48
HIS A  97
HIS A 101
HIS A 196
 PO4  A1238 (-3.9A)
CO  A1239 ( 2.4A)
CO  A1239 ( 3.3A)
CO  A1239 ( 3.2A)
PO4  A1238 (-4.1A)
 0.37A 5nekD-2y8uA:
25.1		 5nekD-2y8uA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 6 ASP A  47
ASP A  48
HIS A  97
HIS A 101
HIS A 196
 PO4  A1238 (-3.9A)
CO  A1239 ( 2.4A)
CO  A1239 ( 3.3A)
CO  A1239 ( 3.2A)
PO4  A1238 (-4.1A)
 0.30A 5nelA-2y8uA:
24.9
5nelD-2y8uA:
25.1		 5nelA-2y8uA:
26.21
5nelD-2y8uA:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		5 / 6 ASP A  47
HIS A  97
HIS A 101
LEU A 194
HIS A 196
 PO4  A1238 (-3.9A)
CO  A1239 ( 3.3A)
CO  A1239 ( 3.2A)
None
PO4  A1238 (-4.1A)
 0.29A 5nelB-2y8uA:
25.2
5nelC-2y8uA:
25.0		 5nelB-2y8uA:
26.21
5nelC-2y8uA:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2y8u CHITIN DEACETYLASE
(Aspergillus
nidulans) 		4 / 7 GLY A 225
SER A 158
THR A 223
ALA A  43
 None
 0.78A 5o96C-2y8uA:
4.3		 5o96C-2y8uA:
22.92