SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y93'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		4 / 7 LEU A   9
ALA A  33
VAL A  54
VAL A  56
 None
 0.75A 1epbA-2y93A:
undetectable		 1epbA-2y93A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		4 / 4 SER A 142
LEU A 191
TYR A 155
GLY A 185
 None
 1.33A 1liiA-2y93A:
7.3		 1liiA-2y93A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		4 / 4 THR A 189
GLY A  13
ASP A  36
ALA A  87
 None
 1.24A 1sg9A-2y93A:
6.0		 1sg9A-2y93A:
21.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		8 / 11 GLY A  12
ALA A  14
SER A  15
ASP A  36
ASP A  59
VAL A  60
ALA A  87
VAL A 114
 None
 0.64A 1uayA-2y93A:
27.0		 1uayA-2y93A:
32.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		8 / 10 GLY A  12
ALA A  14
SER A  15
ASP A  36
ASP A  59
VAL A  60
ALA A  87
VAL A 114
 None
 0.65A 1uayB-2y93A:
27.4		 1uayB-2y93A:
32.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		5 / 12 GLY A  12
ASP A  36
ARG A  41
ASP A  59
ASN A  86
 None
 1.17A 2bm9B-2y93A:
5.2		 2bm9B-2y93A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		6 / 12 GLY A  12
ASP A  36
ARG A  41
ASP A  59
ASN A  86
ALA A  87
 None
 1.16A 2bm9E-2y93A:
4.8		 2bm9E-2y93A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		4 / 7 TYR A 147
PHE A 146
LEU A 249
ALA A 183
 None
 1.14A 2vcvA-2y93A:
undetectable		 2vcvA-2y93A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		5 / 12 GLY A  12
ALA A  20
ASP A  59
VAL A  60
VAL A 114
 None
 1.12A 3dmfA-2y93A:
7.1		 3dmfA-2y93A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		5 / 12 GLY A  12
ALA A  20
LEU A  21
VAL A  60
VAL A 114
 None
 1.06A 3dmhA-2y93A:
7.0		 3dmhA-2y93A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		5 / 12 GLY A  55
ARG A  68
ALA A  69
ARG A  19
ALA A  14
 None
 1.09A 3g89A-2y93A:
6.2		 3g89A-2y93A:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		4 / 5 LEU A 130
ILE A  84
PRO A  85
PHE A 139
 None
 1.21A 3s3vA-2y93A:
1.3		 3s3vA-2y93A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		5 / 12 GLY A 185
ASN A 143
THR A 189
LEU A 225
GLY A 150
 None
 1.02A 3uq6A-2y93A:
6.6		 3uq6A-2y93A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		5 / 12 GLY A 185
ASN A 143
THR A 189
LEU A 225
GLY A 150
 None
 1.06A 3uq6B-2y93A:
5.8		 3uq6B-2y93A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		5 / 12 GLY A 185
ASN A 143
THR A 189
LEU A 225
GLY A 150
 None
 1.05A 3vaqA-2y93A:
6.0		 3vaqA-2y93A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		5 / 12 GLY A 185
ASN A 143
THR A 189
LEU A 225
GLY A 150
 None
 1.09A 3vaqB-2y93A:
6.4		 3vaqB-2y93A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		5 / 12 GLY A 185
ASN A 143
THR A 189
LEU A 225
GLY A 150
 None
 1.03A 3vasA-2y93A:
6.2		 3vasA-2y93A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		4 / 7 LEU A 130
ALA A  70
VAL A  54
ILE A  80
 None
 0.92A 3wsjB-2y93A:
undetectable		 3wsjB-2y93A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		4 / 8 ARG A  43
ALA A  39
LEU A  42
GLY A  55
 None
 0.72A 4xk8a-2y93A:
undetectable		 4xk8a-2y93A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		4 / 7 TYR A 232
ALA A  20
GLY A  16
GLY A  13
 None
 0.87A 5e26A-2y93A:
undetectable
5e26B-2y93A:
undetectable		 5e26A-2y93A:
22.55
5e26B-2y93A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		4 / 7 GLY A  16
GLY A  12
TYR A 232
ALA A  20
 None
 0.87A 5e26C-2y93A:
undetectable
5e26D-2y93A:
undetectable		 5e26C-2y93A:
22.55
5e26D-2y93A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		4 / 8 TYR A 232
ALA A  20
GLY A  16
GLY A  12
 None
 0.85A 5e26C-2y93A:
undetectable
5e26D-2y93A:
undetectable		 5e26C-2y93A:
22.55
5e26D-2y93A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2y93 CIS-2,3-DIHYDROBIPHE
NYL-2,3-DIOL
DEHYDROGENASE
(Comamonas
testosteroni) 		5 / 10 ARG A  43
ALA A  39
LEU A  42
GLY A  55
ILE A  89
 None
 1.22A 5oy01-2y93A:
undetectable
5oy07-2y93A:
undetectable		 5oy01-2y93A:
17.54
5oy07-2y93A:
9.63