SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 2y96 DUAL SPECIFICITY
PHOSPHATASE DUPD1
(Homo
sapiens) 		4 / 8 LEU A  76
VAL A  55
TYR A  63
GLY A  65
 None
SO4  A1208 (-4.1A)
None
None
 0.90A 1s1xA-2y96A:
undetectable		 1s1xA-2y96A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 2y96 DUAL SPECIFICITY
PHOSPHATASE DUPD1
(Homo
sapiens) 		3 / 3 ASP A 139
GLU A  57
TYR A 161
 None
 0.78A 1wsvA-2y96A:
undetectable		 1wsvA-2y96A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2y96 DUAL SPECIFICITY
PHOSPHATASE DUPD1
(Homo
sapiens) 		4 / 8 TYR A 100
VAL A  94
HIS A 146
LEU A  76
 SO4  A1209 ( 4.9A)
None
None
None
 1.07A 4jtrA-2y96A:
undetectable		 4jtrA-2y96A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 2y96 DUAL SPECIFICITY
PHOSPHATASE DUPD1
(Homo
sapiens) 		4 / 8 LEU A 162
GLU A  57
LEU A 136
ILE A 143
 None
 0.71A 5mzjA-2y96A:
undetectable		 5mzjA-2y96A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 2y96 DUAL SPECIFICITY
PHOSPHATASE DUPD1
(Homo
sapiens) 		5 / 9 VAL A 111
HIS A  89
LEU A 159
ARG A 153
ALA A 155
 None
None
None
SO4  A1207 (-3.8A)
None
 1.28A 6c2mB-2y96A:
undetectable		 6c2mB-2y96A:
17.78