SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y9e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 12 LEU X 389
ALA X 378
GLY X 355
LEU X 369
PHE X 600
 None
 1.13A 1brpA-2y9eX:
undetectable		 1brpA-2y9eX:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 9 PHE X 551
ILE X 525
ASP X 540
LEU X 543
PHE X 568
 None
 1.37A 1i00B-2y9eX:
undetectable		 1i00B-2y9eX:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 12 ASN X 188
GLU X 187
ILE X 115
TYR X 116
ALA X 125
 None
 1.26A 1kijB-2y9eX:
undetectable		 1kijB-2y9eX:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 ILE X 280
PHE X 430
TYR X 426
ARG X 267
GLY X 226
 None
 1.09A 2bxmA-2y9eX:
3.5		 2bxmA-2y9eX:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 LEU X 284
LEU X 433
PHE X 430
TYR X 426
GLY X 226
 None
 0.96A 2bxmA-2y9eX:
3.5		 2bxmA-2y9eX:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2003_1
(SERUM ALBUMIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 10 ILE X 280
PHE X 430
TYR X 426
ARG X 238
GLY X 226
 None
 1.48A 2bxqA-2y9eX:
2.0		 2bxqA-2y9eX:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 12 TYR X 426
ILE X 344
LEU X 433
THR X 327
PHE X 345
 None
 1.33A 2qo6A-2y9eX:
undetectable		 2qo6A-2y9eX:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 10 GLY X 255
ALA X 256
ILE X 243
ILE X 450
ILE X 215
 None
 0.92A 2r5qD-2y9eX:
undetectable		 2r5qD-2y9eX:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 10 PHE X 551
ILE X 525
ASP X 540
LEU X 543
PHE X 568
 None
 1.44A 2tsrC-2y9eX:
undetectable		 2tsrC-2y9eX:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 9 PHE X 551
ILE X 525
ASP X 540
LEU X 543
PHE X 568
 None
 1.41A 2tsrD-2y9eX:
undetectable		 2tsrD-2y9eX:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 8 ILE X 280
PHE X 430
ARG X 267
GLY X 226
 None
 0.76A 2vdbA-2y9eX:
undetectable		 2vdbA-2y9eX:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 6 MET X 331
PRO X 220
ILE X 437
LEU X 433
 None
 1.29A 2wekB-2y9eX:
undetectable		 2wekB-2y9eX:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 SER X 181
THR X 230
SER X 236
GLY X 182
PHE X 129
 None
 1.39A 2xf3A-2y9eX:
undetectable		 2xf3A-2y9eX:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 SER X 181
THR X 230
SER X 236
GLY X 182
PHE X 129
 None
 1.41A 2xf3B-2y9eX:
undetectable		 2xf3B-2y9eX:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 SER X 181
THR X 230
SER X 236
GLY X 182
PHE X 129
 None
 1.38A 2xh9A-2y9eX:
undetectable		 2xh9A-2y9eX:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1437_1
(ORF12)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 10 SER X 181
THR X 230
SER X 236
GLY X 182
PHE X 129
 None
 1.40A 2xh9B-2y9eX:
undetectable		 2xh9B-2y9eX:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 5 ILE X 326
PRO X 220
VAL X 381
PHE X 225
 None
 1.16A 2ygnA-2y9eX:
undetectable		 2ygnA-2y9eX:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 12 TYR X 118
PHE X 122
ILE X 685
VAL X 680
PHE X 482
 None
 1.22A 2zznA-2y9eX:
undetectable		 2zznA-2y9eX:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 5 ILE X 280
TYR X 426
ARG X 267
GLY X 226
 None
 0.99A 3b9mA-2y9eX:
3.0		 3b9mA-2y9eX:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 GLY X 255
ALA X 256
ILE X 258
GLY X 451
ILE X 450
 None
 1.12A 3ebzB-2y9eX:
undetectable		 3ebzB-2y9eX:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_1
(O-METHYLTRANSFERASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 4 ASP X 454
SER X 260
PHE X 239
SER X 236
 None
 1.43A 3i5uA-2y9eX:
0.2		 3i5uA-2y9eX:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		3 / 3 ASP X  90
SER X  92
ARG X 689
 None
 0.84A 3loqA-2y9eX:
undetectable		 3loqA-2y9eX:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 12 ILE X 455
GLY X 457
GLU X 459
SER X 181
LYS X 185
 None
 1.46A 3r75A-2y9eX:
undetectable		 3r75A-2y9eX:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 12 ILE X 455
SER X 456
GLY X 457
GLU X 459
GLU X 180
 None
 1.45A 3r75A-2y9eX:
undetectable		 3r75A-2y9eX:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 12 ILE X 455
GLY X 457
GLU X 459
SER X 181
LYS X 185
 None
 1.47A 3r75B-2y9eX:
undetectable		 3r75B-2y9eX:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 12 ILE X 455
SER X 456
GLY X 457
GLU X 459
GLU X 180
 None
 1.48A 3r75B-2y9eX:
undetectable		 3r75B-2y9eX:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 ILE X 455
SER X 456
GLY X 457
GLU X 459
GLU X 180
 None
 1.45A 3r76A-2y9eX:
undetectable		 3r76A-2y9eX:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 ILE X 455
SER X 456
GLY X 457
GLU X 459
GLU X 180
 None
 1.46A 3r76B-2y9eX:
undetectable		 3r76B-2y9eX:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 6 LEU X 421
SER X 417
ARG X 418
LEU X 596
 None
 1.07A 3ravA-2y9eX:
2.5		 3ravA-2y9eX:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 ALA X 183
ASN X 475
ILE X 455
GLY X 457
VAL X 681
 None
 1.21A 3rukD-2y9eX:
undetectable		 3rukD-2y9eX:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S7B_A_SAMA1000_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 GLU X 180
CYH X 678
ASN X 679
ASN X 475
HIS X 572
 None
 1.12A 3s7bA-2y9eX:
0.1		 3s7bA-2y9eX:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S7F_A_SAMA1000_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2
P53 PEPTIDE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 12 GLU X 180
CYH X 678
ASN X 679
ASN X 475
HIS X 572
 None
 1.18A 3s7fA-2y9eX:
0.1
3s7fI-2y9eX:
undetectable		 3s7fA-2y9eX:
19.92
3s7fI-2y9eX:
2.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S7J_A_SAMA1000_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 GLU X 180
CYH X 678
ASN X 679
ASN X 475
HIS X 572
 None
 1.15A 3s7jA-2y9eX:
0.0		 3s7jA-2y9eX:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 8 GLY X 255
ALA X 256
GLY X 451
ILE X 450
 None
 0.63A 3so9A-2y9eX:
undetectable		 3so9A-2y9eX:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 5 PHE X 103
TYR X 110
LEU X  97
ARG X 109
 None
 1.09A 3sudD-2y9eX:
2.1		 3sudD-2y9eX:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 9 PHE X 551
ILE X 525
ASP X 540
LEU X 543
PHE X 568
 None
 1.37A 4eb4C-2y9eX:
undetectable		 4eb4C-2y9eX:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 10 PHE X 551
ILE X 525
ASP X 540
LEU X 543
PHE X 568
 None
 1.39A 4eb4D-2y9eX:
undetectable		 4eb4D-2y9eX:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 6 PHE X 239
ASN X 227
ALA X 224
LEU X 433
 None
 1.04A 4ejgD-2y9eX:
undetectable		 4ejgD-2y9eX:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		3 / 3 PRO X 713
VAL X 726
HIS X 729
 None
 0.71A 4pevC-2y9eX:
undetectable		 4pevC-2y9eX:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 7 GLY X 207
SER X 198
GLY X 201
ALA X 205
 None
 1.01A 5e26A-2y9eX:
undetectable
5e26B-2y9eX:
undetectable		 5e26A-2y9eX:
19.87
5e26B-2y9eX:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 7 LEU X 421
THR X 609
ASP X 605
LEU X 393
 None
 0.97A 5jq7B-2y9eX:
undetectable		 5jq7B-2y9eX:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KJK_A_SAMA501_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 GLU X 180
CYH X 678
ASN X 679
ASN X 475
HIS X 572
 None
 1.11A 5kjkA-2y9eX:
0.1		 5kjkA-2y9eX:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KJL_A_SAMA501_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 GLU X 180
CYH X 678
ASN X 679
ASN X 475
HIS X 572
 None
 1.13A 5kjlA-2y9eX:
0.0		 5kjlA-2y9eX:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KJM_A_SAMA501_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 GLU X 180
CYH X 678
ASN X 679
ASN X 475
HIS X 572
 None
 1.12A 5kjmA-2y9eX:
0.1		 5kjmA-2y9eX:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 7 GLY X 255
ALA X 256
GLY X 451
ILE X 450
 None
 0.65A 5kqyB-2y9eX:
undetectable		 5kqyB-2y9eX:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 8 GLY X 255
ALA X 256
GLY X 451
ILE X 450
 None
 0.63A 5kr1B-2y9eX:
undetectable		 5kr1B-2y9eX:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 10 VAL X 381
HIS X 297
LEU X 298
ALA X 349
THR X 289
 None
 1.22A 5m5cE-2y9eX:
undetectable		 5m5cE-2y9eX:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 5 TYR X 282
ALA X 228
GLN X 271
THR X 230
 None
 1.25A 5n0wB-2y9eX:
1.2		 5n0wB-2y9eX:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 5 TYR X 282
ALA X 228
GLN X 271
THR X 230
 None
 1.13A 5n4iA-2y9eX:
1.2		 5n4iA-2y9eX:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 7 SER X 533
ALA X 631
ILE X 517
LEU X 469
 None
 1.03A 5te8A-2y9eX:
undetectable		 5te8A-2y9eX:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 9 HIS X 651
ILE X 245
ILE X 215
LEU X 216
 None
 0.78A 5vkqB-2y9eX:
undetectable
5vkqC-2y9eX:
2.1		 5vkqB-2y9eX:
18.71
5vkqC-2y9eX:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 LEU X 529
ASP X 530
GLY X 519
ILE X 517
PHE X 466
 None
 0.99A 6gp2A-2y9eX:
undetectable		 6gp2A-2y9eX:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		5 / 11 LEU X 529
ASP X 530
GLY X 519
ILE X 517
PHE X 466
 None
 0.98A 6gp2B-2y9eX:
2.8		 6gp2B-2y9eX:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 2y9e MYOSIN-2
(Dictyostelium
discoideum) 		4 / 5 GLY X 749
LEU X 751
SER X  95
TYR X  96
 None
 1.26A 6ji6A-2y9eX:
undetectable		 6ji6A-2y9eX:
14.19