SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 2y9j PROTEIN PRGH
(Salmonella
enterica) 		4 / 7 ALA A 286
TYR A 285
TYR A 245
PHE A 250
 None
 1.10A 2ajvH-2y9jA:
undetectable
2ajvL-2y9jA:
undetectable		 2ajvH-2y9jA:
23.53
2ajvL-2y9jA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 2y9j PROTEIN PRGH
(Salmonella
enterica) 		5 / 8 GLU A 304
TYR A 346
TYR A 354
PHE A 357
ILE A 327
 None
 1.50A 3jz0B-2y9jA:
undetectable		 3jz0B-2y9jA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 2y9j PROTEIN PRGH
(Salmonella
enterica) 		3 / 3 MET A 267
GLU A 271
LEU A 275
 None
 0.67A 4v2oB-2y9jA:
undetectable		 4v2oB-2y9jA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2y9j LIPOPROTEIN PRGK
(Salmonella
enterica) 		3 / 3 LYS Y  25
LYS Y  53
SER Y  51
 None
 1.36A 5odiA-2y9jY:
undetectable		 5odiA-2y9jY:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 2y9j PROTEIN PRGH
(Salmonella
enterica) 		4 / 6 GLU A 304
ALA A 305
LEU A 307
TYR A 314
 None
 1.06A 5phhA-2y9jA:
undetectable		 5phhA-2y9jA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 2y9j LIPOPROTEIN PRGK
(Salmonella
enterica) 		3 / 3 HIS Y 129
SER Y 149
ARG Y 127
 None
 0.99A 5u63A-2y9jY:
undetectable		 5u63A-2y9jY:
19.25