SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2y9t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 2y9t TUMOR PROTEIN 63
(Homo
sapiens) 		4 / 8 ILE A 601
PHE A 565
LEU A 556
LEU A 553
 None
 0.90A 2w98B-2y9tA:
undetectable		 2w98B-2y9tA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 2y9t TUMOR PROTEIN 63
(Homo
sapiens) 		4 / 7 GLY A 600
ILE A 576
LEU A 584
PHE A 565
 None
 0.79A 4ejjD-2y9tA:
undetectable		 4ejjD-2y9tA:
9.48