SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yb4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 5 HIS A   7
HIS A  75
HIS A 191
ASP A 248
 None
 0.94A 1e9yB-2yb4A:
2.8		 1e9yB-2yb4A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 12 GLY A 182
ALA A 183
THR A  42
VAL A  63
ILE A  81
 None
 1.02A 1fb7A-2yb4A:
undetectable		 1fb7A-2yb4A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 6 HIS A   7
HIS A   9
HIS A  75
HIS A 191
ASP A 248
 None
 0.92A 1fweC-2yb4A:
2.4		 1fweC-2yb4A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 12 LEU A  60
ASN A  61
LEU A  79
GLY A  62
ALA A  49
 None
 1.14A 1gs4A-2yb4A:
undetectable		 1gs4A-2yb4A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 12 GLU A  64
HIS A  39
HIS A  75
HIS A 191
ASP A 248
 None
SO4  A1289 (-4.1A)
None
None
None
 1.42A 1ituA-2yb4A:
3.3		 1ituA-2yb4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 8 GLY A  78
VAL A  63
GLU A  64
ILE A  81
 None
 0.85A 1pk7B-2yb4A:
undetectable		 1pk7B-2yb4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 6 ASP A 127
THR A  20
GLU A  21
GLU A  47
 None
 1.46A 2dttB-2yb4A:
undetectable
2dttC-2yb4A:
undetectable		 2dttB-2yb4A:
17.99
2dttC-2yb4A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 6 ASP A 248
SER A 244
LEU A   6
GLY A 246
 None
 1.01A 2j2pA-2yb4A:
undetectable
2j2pC-2yb4A:
undetectable		 2j2pA-2yb4A:
22.30
2j2pC-2yb4A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 6 ASP A 248
SER A 244
LEU A   6
GLY A 246
 None
 1.03A 2j2pD-2yb4A:
undetectable
2j2pF-2yb4A:
undetectable		 2j2pD-2yb4A:
22.30
2j2pF-2yb4A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O02_B_BEZB802_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 4 ILE A 132
MET A 106
GLN A 105
ARG A 104
 None
 1.41A 2o02B-2yb4A:
0.0		 2o02B-2yb4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 8 LEU A 265
PRO A 192
VAL A 188
GLY A 216
 None
 0.91A 2po5B-2yb4A:
undetectable		 2po5B-2yb4A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 12 LEU A  60
LEU A   6
ARG A 282
SER A 245
LEU A 265
 None
 1.39A 2qd4A-2yb4A:
undetectable		 2qd4A-2yb4A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 8 LEU A 265
PRO A 192
VAL A 188
GLY A 216
 None
 0.87A 2qd5A-2yb4A:
undetectable		 2qd5A-2yb4A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 8 LEU A 265
PRO A 192
VAL A 188
GLY A 216
 None
 0.95A 2qd5B-2yb4A:
undetectable		 2qd5B-2yb4A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 8 ARG A 102
SER A  66
HIS A  39
ASP A  40
 SO4  A1289 (-3.1A)
SO4  A1289 ( 4.7A)
SO4  A1289 (-4.1A)
None
 1.09A 2xadA-2yb4A:
undetectable		 2xadA-2yb4A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 8 ARG A 102
SER A  66
HIS A  39
ASP A  40
 SO4  A1289 (-3.1A)
SO4  A1289 ( 4.7A)
SO4  A1289 (-4.1A)
None
 1.10A 2xadB-2yb4A:
undetectable		 2xadB-2yb4A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 8 ARG A 102
SER A  66
HIS A  39
ASP A  40
 SO4  A1289 (-3.1A)
SO4  A1289 ( 4.7A)
SO4  A1289 (-4.1A)
None
 1.10A 2xadC-2yb4A:
undetectable		 2xadC-2yb4A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 8 ARG A 102
SER A  66
HIS A  39
ASP A  40
 SO4  A1289 (-3.1A)
SO4  A1289 ( 4.7A)
SO4  A1289 (-4.1A)
None
 1.09A 2xadD-2yb4A:
undetectable		 2xadD-2yb4A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 5 ILE A  76
HIS A   7
GLU A 218
HIS A 191
 None
 0.99A 3ljgA-2yb4A:
undetectable		 3ljgA-2yb4A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC600_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 5 GLU A  64
HIS A   7
ARG A 194
ALA A 190
 None
 1.36A 3mbgB-2yb4A:
0.0
3mbgC-2yb4A:
0.0		 3mbgB-2yb4A:
15.97
3mbgC-2yb4A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 7 HIS A  75
ASP A  14
ARG A 134
HIS A 250
 None
None
SO4  A1289 (-3.9A)
None
 1.18A 3zodA-2yb4A:
undetectable		 3zodA-2yb4A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 6 HIS A   9
HIS A  75
GLU A 254
ASP A 248
 None
 1.34A 4blvA-2yb4A:
undetectable		 4blvA-2yb4A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 5 HIS A   7
HIS A  75
HIS A 191
ASP A 248
 None
 0.88A 4h9mA-2yb4A:
5.4		 4h9mA-2yb4A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 12 LEU A  34
LEU A  17
PHE A 249
PRO A  19
ASP A 248
 None
 1.42A 4j7xJ-2yb4A:
undetectable		 4j7xJ-2yb4A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 8 GLY A 246
THR A  37
LEU A  34
PHE A   8
 None
 1.10A 4m5mA-2yb4A:
undetectable		 4m5mA-2yb4A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 6 LEU A  45
HIS A   9
HIS A   7
GLU A  64
 None
 0.97A 4pahA-2yb4A:
undetectable		 4pahA-2yb4A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 12 THR A  37
ARG A 279
VAL A  77
LEU A 276
LEU A  33
 None
 1.37A 4qzuA-2yb4A:
undetectable		 4qzuA-2yb4A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 6 HIS A   7
HIS A   9
HIS A  75
HIS A 191
ASP A 248
 None
 0.83A 4ubpC-2yb4A:
2.4		 4ubpC-2yb4A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		3 / 3 MET A 106
GLN A 105
ARG A 104
 None
 1.12A 5ewzB-2yb4A:
undetectable		 5ewzB-2yb4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 12 ALA A  16
ILE A 280
PHE A   8
GLY A  80
LEU A  45
 None
 1.21A 5fsaA-2yb4A:
undetectable		 5fsaA-2yb4A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 11 ASN A   3
ALA A  32
ILE A 280
PRO A 271
ILE A   4
 None
 1.04A 5kr2B-2yb4A:
undetectable		 5kr2B-2yb4A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 12 GLY A  62
ILE A  23
SER A  10
LEU A  45
ALA A  48
 None
 1.01A 5l0zA-2yb4A:
undetectable		 5l0zA-2yb4A:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 6 ASP A 248
HIS A   9
HIS A 250
HIS A 191
 None
 0.91A 5ncdA-2yb4A:
3.8
5ncdD-2yb4A:
3.8		 5ncdA-2yb4A:
23.79
5ncdD-2yb4A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 8 ASP A 248
HIS A   9
HIS A 250
HIS A 191
 None
 1.00A 5nekB-2yb4A:
3.7		 5nekB-2yb4A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 6 ASP A 248
HIS A   9
HIS A 250
HIS A 191
 None
 0.93A 5nelA-2yb4A:
3.8
5nelD-2yb4A:
2.6		 5nelA-2yb4A:
23.79
5nelD-2yb4A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 10 HIS A   9
HIS A   7
ASP A 248
TYR A 195
HIS A 191
 None
 1.14A 5nzwA-2yb4A:
undetectable		 5nzwA-2yb4A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_A_ACTA402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 5 ILE A 189
HIS A 191
HIS A  75
TYR A 195
 None
 1.37A 5ocsA-2yb4A:
3.3		 5ocsA-2yb4A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		3 / 3 HIS A   9
HIS A  39
HIS A  75
 None
SO4  A1289 (-4.1A)
None
 0.83A 5oexA-2yb4A:
undetectable		 5oexA-2yb4A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		3 / 3 CYH A  41
MET A 131
ASN A 128
 None
 1.35A 5qh8A-2yb4A:
undetectable		 5qh8A-2yb4A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 4 ASP A  38
SER A  13
ASP A  14
HIS A 250
 None
 1.43A 5wyqB-2yb4A:
undetectable		 5wyqB-2yb4A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 11 HIS A 191
HIS A   7
HIS A 250
SER A 223
ASP A 258
 None
 1.27A 5z0fA-2yb4A:
undetectable
5z0fB-2yb4A:
undetectable		 5z0fA-2yb4A:
16.73
5z0fB-2yb4A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 7 VAL A 188
PRO A  58
PHE A  59
LEU A  33
 None
 1.02A 6aycA-2yb4A:
undetectable		 6aycA-2yb4A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		3 / 3 ARG A  29
ARG A  25
ASP A 258
 None
 0.94A 6d8pA-2yb4A:
undetectable		 6d8pA-2yb4A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYN_A_HSMA901_0
(EBONY)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 4 GLU A 218
VAL A 188
LEU A  79
THR A  37
 None
 1.09A 6dynA-2yb4A:
0.0		 6dynA-2yb4A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 5 GLU A 218
VAL A 188
LEU A  79
THR A  37
 None
 1.10A 6dyoA-2yb4A:
1.8		 6dyoA-2yb4A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 4 ILE A 132
MET A 106
GLN A 105
ARG A 104
 None
 1.31A 6fn9B-2yb4A:
0.0		 6fn9B-2yb4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		5 / 11 ILE A  76
HIS A 191
ASP A 248
GLY A 246
SER A 221
 None
 1.23A 6ieyA-2yb4A:
undetectable
6ieyB-2yb4A:
undetectable		 6ieyA-2yb4A:
21.73
6ieyB-2yb4A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 2yb4 AMIDOHYDROLASE
(Chromobacterium
violaceum) 		4 / 6 LEU A  45
HIS A   9
HIS A   7
GLU A  64
 None
 0.98A 6pahA-2yb4A:
undetectable		 6pahA-2yb4A:
23.43