SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yb6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.87A 1c6yB-2yb6A:
undetectable		 1c6yB-2yb6A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.89A 1c6zA-2yb6A:
undetectable		 1c6zA-2yb6A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.91A 1c6zB-2yb6A:
undetectable		 1c6zB-2yb6A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.83A 1hsgB-2yb6A:
undetectable		 1hsgB-2yb6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 11 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.85A 1n49B-2yb6A:
undetectable		 1n49B-2yb6A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 11 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.82A 1n49C-2yb6A:
undetectable		 1n49C-2yb6A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.86A 1sdtB-2yb6A:
undetectable		 1sdtB-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 11 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.86A 1sdvB-2yb6A:
undetectable		 1sdvB-2yb6A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.87A 2avoB-2yb6A:
undetectable		 2avoB-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.84A 2avsA-2yb6A:
undetectable		 2avsA-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.89A 2avsB-2yb6A:
undetectable		 2avsB-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.80A 2avvB-2yb6A:
undetectable		 2avvB-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.80A 2avvD-2yb6A:
undetectable		 2avvD-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.86A 2bpxB-2yb6A:
undetectable		 2bpxB-2yb6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.87A 2f8gB-2yb6A:
undetectable		 2f8gB-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.78A 2o4kB-2yb6A:
undetectable		 2o4kB-2yb6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.81A 2o4lB-2yb6A:
undetectable		 2o4lB-2yb6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.80A 2o4sA-2yb6A:
undetectable		 2o4sA-2yb6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.85A 2q63A-2yb6A:
undetectable		 2q63A-2yb6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.85A 2q63B-2yb6A:
undetectable		 2q63B-2yb6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.82A 2q64A-2yb6A:
undetectable		 2q64A-2yb6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.81A 2q64B-2yb6A:
undetectable		 2q64B-2yb6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.81A 2qakA-2yb6A:
undetectable		 2qakA-2yb6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.85A 2r5pB-2yb6A:
undetectable		 2r5pB-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		4 / 8 VAL A  22
PRO A  21
THR A 107
SER A 111
 None
 1.00A 2v32C-2yb6A:
undetectable
2v32D-2yb6A:
undetectable		 2v32C-2yb6A:
18.86
2v32D-2yb6A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.76A 3bvbA-2yb6A:
undetectable		 3bvbA-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.83A 3d1zA-2yb6A:
undetectable		 3d1zA-2yb6A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 10 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.84A 3ekpD-2yb6A:
undetectable		 3ekpD-2yb6A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.80A 3el1B-2yb6A:
undetectable		 3el1B-2yb6A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.80A 3jvyB-2yb6A:
undetectable		 3jvyB-2yb6A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.84A 3jw2B-2yb6A:
undetectable		 3jw2B-2yb6A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.83A 3k4vB-2yb6A:
undetectable		 3k4vB-2yb6A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.82A 3nu5A-2yb6A:
undetectable		 3nu5A-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.83A 3nu5B-2yb6A:
undetectable		 3nu5B-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.85A 3oxcA-2yb6A:
undetectable		 3oxcA-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.81A 3oxxA-2yb6A:
undetectable		 3oxxA-2yb6A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.80A 3pwrB-2yb6A:
undetectable		 3pwrB-2yb6A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		4 / 6 TYR A 137
PHE A  48
PRO A  47
LEU A 113
 None
 1.29A 3tgvB-2yb6A:
undetectable		 3tgvB-2yb6A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		4 / 6 TYR A 137
PHE A  48
PRO A  47
LEU A 113
 None
 1.41A 3tgvD-2yb6A:
undetectable		 3tgvD-2yb6A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.91A 3tkgD-2yb6A:
undetectable		 3tkgD-2yb6A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.83A 3tkwB-2yb6A:
undetectable		 3tkwB-2yb6A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.85A 3tl9B-2yb6A:
undetectable		 3tl9B-2yb6A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.83A 4jecB-2yb6A:
undetectable		 4jecB-2yb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.77A 4njvD-2yb6A:
undetectable		 4njvD-2yb6A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		4 / 5 LEU A  55
LEU A  92
PHE A  72
LEU A 112
 None
 0.94A 5gtrA-2yb6A:
undetectable		 5gtrA-2yb6A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		4 / 6 ARG A   8
ARG A  15
LEU A  16
ALA A  38
 None
 1.06A 6b89B-2yb6A:
undetectable		 6b89B-2yb6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.80A 6dh3B-2yb6A:
undetectable		 6dh3B-2yb6A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.91A 6dh6A-2yb6A:
undetectable		 6dh6A-2yb6A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.80A 6dh6B-2yb6A:
undetectable		 6dh6B-2yb6A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.80A 6difB-2yb6A:
undetectable		 6difB-2yb6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B
(Homo
sapiens) 		5 / 12 GLY A  26
ALA A  38
VAL A  70
ILE A 109
ILE A  57
 None
 0.79A 6dilB-2yb6A:
undetectable		 6dilB-2yb6A:
18.18