SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ybr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 2ybr SINGLE CHAIN
ANTIBODY FRAGMENT
9004G
(Homo
sapiens) 		4 / 4 SER A 103
LEU A  37
TYR B 168
GLY A  99
 None
 1.26A 1liiA-2ybrA:
undetectable		 1liiA-2ybrA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 2ybr SINGLE CHAIN
ANTIBODY FRAGMENT
9004G
BETA-MAMMAL TOXIN
CN2
(Homo
sapiens;
Centruroides
noxius) 		4 / 8 ASP B 182
SER B 163
TYR B 164
TYR C  42
 None
 1.36A 2bteD-2ybrB:
undetectable		 2bteD-2ybrB:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 2ybr SINGLE CHAIN
ANTIBODY FRAGMENT
9004G
BETA-MAMMAL TOXIN
CN2
(Homo
sapiens;
Centruroides
noxius) 		4 / 8 ASP B 182
SER B 163
TYR B 164
TYR C  42
 None
 1.39A 2v0gA-2ybrB:
undetectable		 2v0gA-2ybrB:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2ybr SINGLE CHAIN
ANTIBODY FRAGMENT
9004G
(Homo
sapiens) 		4 / 7 ALA A  92
THR A  91
VAL A 113
GLU A  89
 None
 0.84A 5ecoD-2ybrA:
undetectable		 5ecoD-2ybrA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2ybr SINGLE CHAIN
ANTIBODY FRAGMENT
9004G
(Homo
sapiens) 		4 / 8 TRP A 107
TYR B 219
ARG B 228
GLN B 221
 None
 1.17A 5tzoA-2ybrA:
undetectable		 5tzoA-2ybrA:
26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2ybr SINGLE CHAIN
ANTIBODY FRAGMENT
9004G
BETA-MAMMAL TOXIN
CN2
(Homo
sapiens;
Centruroides
noxius) 		3 / 3 THR C  10
GLU C  28
ASN A  31
 None
 0.92A 6nj9K-2ybrC:
undetectable		 6nj9K-2ybrC:
11.56