SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yc2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 2yc2 SMALL RAB-RELATED
GTPASE
(Chlamydomonas
reinhardtii) 		4 / 9 ILE C 182
ALA C  20
VAL C  19
CYH C  17
 None
 1.03A 2vufB-2yc2C:
undetectable		 2vufB-2yc2C:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 2yc2 SMALL RAB-RELATED
GTPASE
(Chlamydomonas
reinhardtii) 		4 / 7 GLU C 109
TRP C 155
LEU C 161
ASN C 159
 None
 1.37A 3k8mB-2yc2C:
undetectable		 3k8mB-2yc2C:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 2yc2 SMALL RAB-RELATED
GTPASE
(Chlamydomonas
reinhardtii) 		4 / 8 ALA C 156
GLN C 153
LEU C 133
ASP C 162
 None
 0.76A 3qj7A-2yc2C:
undetectable
3qj7D-2yc2C:
undetectable		 3qj7A-2yc2C:
22.10
3qj7D-2yc2C:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 2yc2 INTRAFLAGELLAR
TRANSPORT PROTEIN 25
(Chlamydomonas
reinhardtii) 		3 / 3 ASP A  33
GLY A  31
ASP A  30
 None
None
CA  A 201 (-3.5A)
 0.69A 4xdtA-2yc2A:
undetectable		 4xdtA-2yc2A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 2yc2 INTRAFLAGELLAR
TRANSPORT PROTEIN 25
(Chlamydomonas
reinhardtii) 		5 / 10 GLY A  11
ASP A   3
TYR A   4
LEU A  51
LEU A  49
 None
 1.16A 4xj7A-2yc2A:
undetectable
4xj7B-2yc2A:
undetectable		 4xj7A-2yc2A:
22.18
4xj7B-2yc2A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 2yc2 SMALL RAB-RELATED
GTPASE
(Chlamydomonas
reinhardtii) 		5 / 10 VAL C 102
ALA C 135
SER C 167
PHE C 163
THR C 157
 None
 1.42A 5mm4B-2yc2C:
undetectable		 5mm4B-2yc2C:
23.53