SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ycd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 4 GLY A  31
LEU A  32
GLY A  29
ARG A  30
 None
GTB  A 501 (-4.0A)
None
GTB  A 501 ( 4.9A)
 1.12A 1j7kA-2ycdA:
undetectable		 1j7kA-2ycdA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		5 / 11 GLN A  78
ILE A  89
VAL A  45
LEU A 180
ALA A 176
 None
 1.18A 1n4hA-2ycdA:
undetectable		 1n4hA-2ycdA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 6 ILE A 179
TRP A  40
PHE A 213
GLU A  43
 None
 1.38A 1nsiA-2ycdA:
undetectable
1nsiB-2ycdA:
undetectable		 1nsiA-2ycdA:
19.67
1nsiB-2ycdA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 6 TRP A  40
PHE A 213
GLU A  43
ILE A 179
 None
 1.35A 1nsiA-2ycdA:
undetectable
1nsiB-2ycdA:
undetectable		 1nsiA-2ycdA:
19.67
1nsiB-2ycdA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 6 ILE A 179
TRP A  40
PHE A 213
GLU A  43
 None
 1.46A 1nsiC-2ycdA:
undetectable
1nsiD-2ycdA:
undetectable		 1nsiC-2ycdA:
19.67
1nsiD-2ycdA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 6 TRP A  40
PHE A 213
GLU A  43
ILE A 179
 None
 1.35A 1nsiC-2ycdA:
undetectable
1nsiD-2ycdA:
undetectable		 1nsiC-2ycdA:
19.67
1nsiD-2ycdA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 7 ILE A 179
TRP A  40
PHE A 213
GLU A  43
 None
 1.41A 2nsiA-2ycdA:
undetectable
2nsiB-2ycdA:
undetectable		 2nsiA-2ycdA:
19.67
2nsiB-2ycdA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 7 TRP A  40
PHE A 213
GLU A  43
ILE A 179
 None
 1.43A 2nsiA-2ycdA:
undetectable
2nsiB-2ycdA:
undetectable		 2nsiA-2ycdA:
19.67
2nsiB-2ycdA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 7 TRP A  40
PHE A 213
GLU A  43
ILE A 179
 None
 1.43A 2nsiC-2ycdA:
0.3
2nsiD-2ycdA:
undetectable		 2nsiC-2ycdA:
19.67
2nsiD-2ycdA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 5 LEU A  42
ARG A  39
ALA A  41
ILE A  19
 None
 1.10A 2qhfA-2ycdA:
undetectable		 2qhfA-2ycdA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 8 GLN A 105
PRO A 102
GLY A  99
MET A 115
 None
 0.90A 2y6rB-2ycdA:
undetectable		 2y6rB-2ycdA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 7 ILE A 179
TRP A  40
PHE A 213
GLU A  43
 None
 1.39A 3e7gA-2ycdA:
undetectable
3e7gB-2ycdA:
undetectable		 3e7gA-2ycdA:
19.57
3e7gB-2ycdA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 7 TRP A  40
PHE A 213
GLU A  43
ILE A 179
 None
 1.38A 3e7gA-2ycdA:
undetectable
3e7gB-2ycdA:
undetectable		 3e7gA-2ycdA:
19.57
3e7gB-2ycdA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 7 ILE A 179
TRP A  40
PHE A 213
GLU A  43
 None
 1.41A 3e7gC-2ycdA:
undetectable
3e7gD-2ycdA:
0.2		 3e7gC-2ycdA:
19.57
3e7gD-2ycdA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 8 TRP A  40
PHE A 213
GLU A  43
ILE A 179
 None
 1.42A 3e7gC-2ycdA:
undetectable
3e7gD-2ycdA:
0.2		 3e7gC-2ycdA:
19.57
3e7gD-2ycdA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 7 GLU A 136
ARG A 137
GLU A 143
PRO A 140
 None
 1.40A 3ql6A-2ycdA:
undetectable		 3ql6A-2ycdA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 7 TRP A  40
PHE A 213
GLU A  43
ILE A 179
 None
 1.45A 4nosA-2ycdA:
0.5
4nosB-2ycdA:
undetectable		 4nosA-2ycdA:
19.57
4nosB-2ycdA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 6 TRP A  40
PHE A 213
GLU A  43
ILE A 179
 None
 1.42A 4nosC-2ycdA:
undetectable
4nosD-2ycdA:
undetectable		 4nosC-2ycdA:
19.57
4nosD-2ycdA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2ycd GLUTATHIONE
S-TRANSFERASE
(Agrobacterium
tumefaciens) 		3 / 3 ASP A  27
PHE A 217
ARG A 186
 None
 1.15A 5yw0A-2ycdA:
undetectable		 5yw0A-2ycdA:
23.12