SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DMI_A_BHSA1610_1 (NITRIC OXIDE SYNTHASE)	2yd7	PTPRD PROTEIN (Homo sapiens)	4 / 8	VAL A 115 ARG A 68 ALA A 41 GLU A 93	None None None PO4 A1221 (-4.2A)	1.08A	1dmiA-2yd7A: undetectable 1dmiB-2yd7A: undetectable	1dmiA-2yd7A: 18.88 1dmiB-2yd7A: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OC8_A_HU5A999_1 (HEPATITIS C VIRUS)	2yd7	PTPRD PROTEIN (Homo sapiens)	5 / 12	ARG A 83 LEU A 113 PHE A 43 ALA A 41 VAL A 40	None	0.92A	2oc8A-2yd7A: undetectable	2oc8A-2yd7A: 25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E4D_B_BEZB202_0 (HYDROXYNITRILE LYASE)	2yd7	PTPRD PROTEIN (Homo sapiens)	4 / 7	VAL A 31 ARG A 28 VAL A 202 THR A 158	None	1.02A	5e4dA-2yd7A: undetectable 5e4dB-2yd7A: undetectable	5e4dA-2yd7A: 20.33 5e4dB-2yd7A: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V0V_A_8QPA613_1 (SERUM ALBUMIN)	2yd7	PTPRD PROTEIN (Homo sapiens)	4 / 8	ARG A 179 ALA A 203 SER A 206 GLY A 151	None	0.91A	5v0vA-2yd7A: undetectable	5v0vA-2yd7A: 16.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DMI_A_BHSA1610_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","2yd7","PTPRD PROTEIN","Homo sapiens",4,"VAL A 115;ARG A  68;ALA A  41;GLU A  93","None;None;None;PO4 A1221 (-4.2A)","1.08A","1dmiA-2yd7A:undetectable;1dmiB-2yd7A:undetectable","1dmiA-2yd7A:18.88;1dmiB-2yd7A:18.88"],["2OC8_A_HU5A999_1","HEPATITIS C VIRUS","2yd7","PTPRD PROTEIN","Homo sapiens",5,"ARG A  83;LEU A 113;PHE A  43;ALA A  41;VAL A  40","None","0.92A","2oc8A-2yd7A:undetectable","2oc8A-2yd7A:25.74"],["5E4D_B_BEZB202_0","HYDROXYNITRILE LYASE","2yd7","PTPRD PROTEIN","Homo sapiens",4,"VAL A  31;ARG A  28;VAL A 202;THR A 158","None","1.02A","5e4dA-2yd7A:undetectable;5e4dB-2yd7A:undetectable","5e4dA-2yd7A:20.33;5e4dB-2yd7A:20.33"],["5V0V_A_8QPA613_1","SERUM ALBUMIN","2yd7","PTPRD PROTEIN","Homo sapiens",4,"ARG A 179;ALA A 203;SER A 206;GLY A 151","None","0.91A","5v0vA-2yd7A:undetectable","5v0vA-2yd7A:16.30"]]