SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ydl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 2ydl SH3
DOMAIN-CONTAINING
KINASE-BINDING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 291
ASP A 292
ILE A 288
TYR A 278
ALA A 280
 None
 1.33A 1oltA-2ydlA:
undetectable		 1oltA-2ydlA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 2ydl SH3
DOMAIN-CONTAINING
KINASE-BINDING
PROTEIN 1
(Homo
sapiens) 		4 / 6 LEU A 296
THR A 295
LEU A 286
ASP A 320
 None
 1.10A 2wm3A-2ydlA:
undetectable		 2wm3A-2ydlA:
12.12