SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ydy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 6 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.44A 1usqB-2ydyA:
undetectable		 1usqB-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 6 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.43A 1usqC-2ydyA:
undetectable		 1usqC-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 6 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.43A 1usqD-2ydyA:
undetectable		 1usqD-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 6 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.44A 1usqE-2ydyA:
undetectable		 1usqE-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 7 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.45A 1usqF-2ydyA:
undetectable		 1usqF-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		4 / 8 LEU A 295
VAL A 227
VAL A 179
VAL A 139
 None
 0.95A 2bdmA-2ydyA:
undetectable		 2bdmA-2ydyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		3 / 3 ALA A 228
VAL A 230
TRP A 250
 None
 0.97A 2izqA-2ydyA:
undetectable
2izqB-2ydyA:
undetectable		 2izqA-2ydyA:
5.91
2izqB-2ydyA:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 6 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.49A 2jkjA-2ydyA:
undetectable		 2jkjA-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 6 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.48A 2jkjB-2ydyA:
undetectable		 2jkjB-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 6 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.48A 2jkjC-2ydyA:
undetectable		 2jkjC-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 5 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.48A 2jkjD-2ydyA:
undetectable		 2jkjD-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 7 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.48A 2jkjE-2ydyA:
undetectable		 2jkjE-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 5 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.49A 2jkjF-2ydyA:
undetectable		 2jkjF-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 6 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.44A 2jklB-2ydyA:
undetectable		 2jklB-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		5 / 7 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.44A 2jklE-2ydyA:
undetectable		 2jklE-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		3 / 3 ASP A 296
ARG A 148
ARG A 308
 None
 0.89A 3k37A-2ydyA:
undetectable		 3k37A-2ydyA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA
(Homo
sapiens) 		4 / 7 TYR A 186
GLY A 314
SER A 318
LEU A 319
 None
 1.18A 5bphB-2ydyA:
4.3		 5bphB-2ydyA:
22.61