SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yew'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 2yew E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		5 / 12 ILE C 148
PRO C 149
ASP C 261
ILE C 133
THR C 146
 None
 1.28A 1kijB-2yewC:
undetectable		 1kijB-2yewC:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2yew E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		5 / 10 MET C 166
SER C 238
GLY C  16
SER C  32
ILE C  15
 None
 1.33A 1pw7A-2yewC:
undetectable		 1pw7A-2yewC:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2yew CAPSID PROTEIN
(Barmah
Forest
virus) 		5 / 10 GLY A 117
GLY A 206
THR A 135
ASN A 116
VAL A 115
 None
 1.30A 1pwyE-2yewA:
undetectable		 1pwyE-2yewA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 2yew E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		5 / 12 VAL C  31
ILE C  33
ILE C  47
ILE C 100
LEU C  82
 None
 1.04A 1qhyA-2yewC:
undetectable		 1qhyA-2yewC:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 2yew E1 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		3 / 3 ASP B 202
GLU B 246
TYR B 180
 None
 0.84A 1wsvA-2yewB:
undetectable		 1wsvA-2yewB:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2yew E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		4 / 7 ARG C  79
GLY C  54
SER C  80
GLU C  78
 None
 1.11A 2c8aD-2yewC:
undetectable		 2c8aD-2yewC:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 2yew E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		5 / 12 GLU C 162
ARG C 161
ILE C 253
TYR C   8
PHE C  99
 None
 1.09A 2qeoA-2yewC:
undetectable		 2qeoA-2yewC:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2yew E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		4 / 8 VAL C 172
PRO C 173
PRO C 242
VAL C 241
 None
 0.96A 2v32C-2yewC:
undetectable
2v32D-2yewC:
undetectable		 2v32C-2yewC:
18.33
2v32D-2yewC:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 2yew E1 ENVELOPE
GLYCOPROTEIN
E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus;
Barmah
Forest
virus) 		3 / 3 PRO B  56
ASN C 237
HIS C 167
 None
 0.98A 4ma3H-2yewB:
undetectable
4ma3L-2yewB:
3.4		 4ma3H-2yewB:
21.08
4ma3L-2yewB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 2yew E1 ENVELOPE
GLYCOPROTEIN
E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		3 / 3 GLN C 306
HIS C 304
ARG B 253
 None
 1.11A 4qyqA-2yewC:
undetectable		 4qyqA-2yewC:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 2yew E1 ENVELOPE
GLYCOPROTEIN
E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		3 / 3 GLN C 306
HIS C 304
ARG B 253
 None
 1.09A 4qyqB-2yewC:
undetectable		 4qyqB-2yewC:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 2yew CAPSID PROTEIN
(Barmah
Forest
virus) 		4 / 4 LEU A 221
ILE A 219
PRO A 129
LEU A 154
 None
 1.23A 5eb3A-2yewA:
undetectable		 5eb3A-2yewA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2yew E1 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		4 / 6 ALA B 357
THR B 358
VAL B 361
VAL B 367
 None
 0.92A 5eckA-2yewB:
undetectable		 5eckA-2yewB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2yew E1 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		4 / 6 ALA B 357
THR B 358
VAL B 361
VAL B 367
 None
 0.88A 5eckD-2yewB:
undetectable		 5eckD-2yewB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2yew E1 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		4 / 6 ALA B 357
THR B 358
VAL B 361
VAL B 367
 None
 1.00A 5eclA-2yewB:
undetectable		 5eclA-2yewB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5H_C_ACTC1742_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SUBUNIT)		 2yew CAPSID PROTEIN
(Barmah
Forest
virus) 		4 / 5 ASP A 124
LYS A 125
TRP A 237
THR A 171
 None
 1.27A 5g5hC-2yewA:
0.0		 5g5hC-2yewA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 2yew E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		4 / 8 TYR C 227
THR C 193
THR C 208
PRO C 169
 None
 1.07A 5jhdE-2yewC:
undetectable
5jhdG-2yewC:
1.0		 5jhdE-2yewC:
18.91
5jhdG-2yewC:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 2yew CAPSID PROTEIN
(Barmah
Forest
virus) 		4 / 5 VAL A 159
THR A 145
ASP A 137
LEU A 141
 None
 1.33A 5m0iB-2yewA:
undetectable		 5m0iB-2yewA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2yew E1 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		3 / 3 ILE B 330
VAL B 369
PRO B 294
 None
 0.65A 5uunA-2yewB:
undetectable		 5uunA-2yewB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 2yew CAPSID PROTEIN
(Barmah
Forest
virus) 		5 / 11 PHE A 188
GLY A 191
ASN A 238
VAL A 234
LYS A 174
 None
 1.33A 5yjsA-2yewA:
undetectable		 5yjsA-2yewA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 2yew E1 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus) 		4 / 5 GLN B 204
THR B  48
THR B  53
GLY B 195
 None
 1.11A 6gbnC-2yewB:
undetectable		 6gbnC-2yewB:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 2yew E1 ENVELOPE
GLYCOPROTEIN
E2 ENVELOPE
GLYCOPROTEIN
(Barmah
Forest
virus;
Barmah
Forest
virus) 		3 / 3 ASP C 171
SER C 238
SER B  57
 None
 0.75A 6mxtA-2yewC:
undetectable		 6mxtA-2yewC:
19.89