SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yfh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT2_A_SAMA301_0 (FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 12	GLY A 238 ALA A 260 SER A 235 ASP A 262 GLN A 308	None	1.05A	1nt2A-2yfhA: undetectable	1nt2A-2yfhA: 18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 12	LEU A 214 LEU A 318 ALA A 317 ILE A 316 ALA A 366	None	1.19A	2bxpA-2yfhA: undetectable	2bxpA-2yfhA: 20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYR_B_SVRB401_4 (NAD-DEPENDENT DEACETYLASE SIRTUIN-5)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 5	ALA A 341 ALA A 371 ALA A 370 VAL A 426	None	0.93A	2nyrB-2yfhA: undetectable	2nyrB-2yfhA: 21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PGZ_D_COCD401_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 6	TYR A 189 TYR A 181 GLN A 180 ILE A 184	None	1.38A	2pgzD-2yfhA: undetectable 2pgzE-2yfhA: undetectable	2pgzD-2yfhA: 18.79 2pgzE-2yfhA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WD9_A_IBPA1570_1 (ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 7	LEU A 101 VAL A 80 GLY A 108 ARG A 94	None	0.76A	2wd9A-2yfhA: 4.1	2wd9A-2yfhA: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WD9_B_IBPB1570_1 (ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 8	LEU A 101 VAL A 80 GLY A 108 ARG A 94	None	0.75A	2wd9B-2yfhA: 3.9	2wd9B-2yfhA: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZH_A_D2VA602_1 (CYTOCHROME P450 2R1)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 12	PHE A 365 VAL A 426 ALA A 429 ALA A 343 VAL A 342	None	1.12A	3czhA-2yfhA: undetectable	3czhA-2yfhA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_E_TFPE201_1 (PROTEIN S100-A4)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 7	PHE A 434 GLY A 433 PHE A 113 PHE A 109	None	0.93A	3ko0D-2yfhA: undetectable 3ko0E-2yfhA: 0.6	3ko0D-2yfhA: 12.47 3ko0E-2yfhA: 12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_O_TFPO201_1 (PROTEIN S100-A4)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 8	PHE A 109 PHE A 434 GLY A 433 PHE A 113	None	0.97A	3ko0O-2yfhA: 0.3 3ko0Q-2yfhA: undetectable	3ko0O-2yfhA: 12.47 3ko0Q-2yfhA: 12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_Q_TFPQ201_1 (PROTEIN S100-A4)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 8	PHE A 434 GLY A 433 PHE A 113 PHE A 109	None	0.98A	3ko0O-2yfhA: 0.3 3ko0Q-2yfhA: undetectable	3ko0O-2yfhA: 12.47 3ko0Q-2yfhA: 12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NMU_F_SAMF228_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE NOP5/NOP56 RELATED PROTEIN)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 12	GLY A 238 ALA A 260 SER A 235 ASP A 262 GLN A 308	None	1.28A	3nmuA-2yfhA: undetectable 3nmuF-2yfhA: undetectable	3nmuA-2yfhA: 23.36 3nmuF-2yfhA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ROX_A_TEPA266_1 (APOLIPOPROTEIN A-I-BINDING PROTEIN)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 8	ALA A 394 VAL A 397 ASP A 398 LEU A 401	None	0.69A	3roxA-2yfhA: 6.1	3roxA-2yfhA: 19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TM4_B_SAMB401_0 (TRNA (GUANINE N2-)-METHYLTRANSFERA SE TRM14)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 12	ALA A 343 LEU A 425 GLY A 368 ALA A 377 LEU A 401	None	1.20A	3tm4B-2yfhA: 4.8	3tm4B-2yfhA: 23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UT5_D_LOCD502_1 (TUBULIN BETA CHAIN)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 12	ALA A 220 LEU A 222 ALA A 341 ALA A 366 ILE A 316	None	0.99A	3ut5D-2yfhA: undetectable	3ut5D-2yfhA: 21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VAQ_A_ADNA401_2 (PUTATIVE ADENOSINE KINASE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 4	LEU A 364 ALA A 366 PHE A 217 ASN A 424	None	1.46A	3vaqA-2yfhA: undetectable	3vaqA-2yfhA: 21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VAS_A_ADNA401_2 (PUTATIVE ADENOSINE KINASE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 4	LEU A 364 ALA A 366 PHE A 217 ASN A 424	None	1.49A	3vasA-2yfhA: undetectable	3vasA-2yfhA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F84_A_SAMA501_0 (GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERAS E)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 12	GLY A 127 GLY A 91 VAL A 80 GLN A 111 VAL A 99	None	1.18A	4f84A-2yfhA: 4.3	4f84A-2yfhA: 22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FE1_A_PQNA846_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 PHOTOSYSTEM I REACTION CENTER SUBUNIT IX)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 10	PHE A 229 ALA A 220 LEU A 222 GLY A 228 ALA A 354	None	1.16A	4fe1A-2yfhA: undetectable 4fe1J-2yfhA: undetectable	4fe1A-2yfhA: 22.49 4fe1J-2yfhA: 8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4H2F_A_ADNA601_1 (5'-NUCLEOTIDASE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 9	ARG A 206 GLY A 202 ARG A 198 GLY A 195 PHE A 200	None	0.98A	4h2fA-2yfhA: undetectable	4h2fA-2yfhA: 23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4H2G_A_ADNA603_1 (5'-NUCLEOTIDASE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 9	ARG A 206 GLY A 202 ARG A 198 GLY A 195 PHE A 200	None	0.93A	4h2gA-2yfhA: undetectable	4h2gA-2yfhA: 23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A206_1 (UNCHARACTERIZED PROTEIN)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 10	PHE A 61 TYR A 153 PHE A 148 ARG A 79 LEU A 93	None	1.33A	4kouA-2yfhA: 0.0	4kouA-2yfhA: 16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L6V_1_PQN12001_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 FUSION PROTEIN OF PHOTOSYSTEM I SUBUNIT III AND SUBUNIT IX)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 11	PHE A 229 ALA A 220 LEU A 222 GLY A 228 ALA A 354	None	1.08A	4l6v1-2yfhA: undetectable 4l6v6-2yfhA: undetectable	4l6v1-2yfhA: 21.30 4l6v6-2yfhA: 13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L6V_A_PQNA2001_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 FUSION PROTEIN OF PHOTOSYSTEM I SUBUNIT III AND SUBUNIT IX)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 9	PHE A 229 ALA A 220 LEU A 222 GLY A 228 ALA A 331	None	1.26A	4l6va-2yfhA: undetectable 4l6vf-2yfhA: undetectable	4l6va-2yfhA: 21.30 4l6vf-2yfhA: 13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L6V_A_PQNA2001_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 FUSION PROTEIN OF PHOTOSYSTEM I SUBUNIT III AND SUBUNIT IX)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 9	PHE A 229 ALA A 220 LEU A 222 GLY A 228 ALA A 354	None	1.10A	4l6va-2yfhA: undetectable 4l6vf-2yfhA: undetectable	4l6va-2yfhA: 21.30 4l6vf-2yfhA: 13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L78_A_ACTA1327_0 (PHOSPHORIBOSYLFORMYL GLYCINAMIDINE SYNTHASE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 4	VAL A 23 THR A 25 GLU A 27 GLU A 28	None	1.42A	4l78A-2yfhA: undetectable	4l78A-2yfhA: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LUF_A_ACTA605_0 (SERUM ALBUMIN)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 4	ALA A 366 HIS A 409 PHE A 217 LEU A 222	None	1.31A	4lufA-2yfhA: 0.0	4lufA-2yfhA: 20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LUH_A_ACTA609_0 (SERUM ALBUMIN)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 4	ALA A 366 HIS A 409 PHE A 217 LEU A 222	None	1.33A	4luhA-2yfhA: 0.0	4luhA-2yfhA: 20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_A_GCSA301_1 (CHITOSANASE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	3 / 3	TYR A 181 GLY A 157 PRO A 158	None	0.65A	4qwpA-2yfhA: undetectable	4qwpA-2yfhA: 20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP1_A_LDPA708_1 (DOPAMINE TRANSPORTER, ISOFORM B)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 10	ASP A 398 ALA A 246 VAL A 215 TYR A 216 GLY A 211	None	1.13A	4xp1A-2yfhA: undetectable	4xp1A-2yfhA: 21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4G_A_IPHA905_0 (PROTEIN ARGONAUTE-2)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 5	ASP A 327 ALA A 331 THR A 351 THR A 350	None	1.34A	4z4gA-2yfhA: 3.9	4z4gA-2yfhA: 18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_B_SORB1342_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 7	ILE A 86 GLU A 56 GLY A 124 GLY A 123	None	0.86A	5a06B-2yfhA: 3.2	5a06B-2yfhA: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HG0_A_SAMA301_0 (PANTOTHENATE SYNTHETASE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 12	GLY A 213 LEU A 401 GLY A 375 THR A 210 LEU A 214	None	1.24A	5hg0A-2yfhA: undetectable	5hg0A-2yfhA: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IK1_A_CAMA503_0 (CAMPHOR 5-MONOOXYGENASE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	5 / 7	GLY A 165 THR A 194 VAL A 162 ASP A 161 ILE A 156	None	1.37A	5ik1A-2yfhA: undetectable	5ik1A-2yfhA: 23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_A_1GNA615_1 (PHIAB6 TAILSPIKE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	3 / 3	TYR A 43 TYR A 419 GLN A 435	None	1.15A	5jsdA-2yfhA: undetectable 5jsdB-2yfhA: undetectable	5jsdA-2yfhA: 21.79 5jsdB-2yfhA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_B_1GNB606_1 (PHIAB6 TAILSPIKE)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	3 / 3	TYR A 43 TYR A 419 GLN A 435	None	1.16A	5jsdB-2yfhA: undetectable 5jsdC-2yfhA: undetectable	5jsdB-2yfhA: 21.79 5jsdC-2yfhA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_B_CVIB301_1 (REGULATORY PROTEIN TETR)	2yfh	GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE (Escherichia coli; [Clostridium] symbiosum)	4 / 8	GLY A 84 ARG A 79 ASP A 161 ASP A 115	None	1.03A	5vlmB-2yfhA: undetectable	5vlmB-2yfhA: 18.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NT2_A_SAMA301_0","FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"GLY A 238;ALA A 260;SER A 235;ASP A 262;GLN A 308","None","1.05A","1nt2A-2yfhA:undetectable","1nt2A-2yfhA:18.35"],["2BXP_A_P1ZA3001_1","SERUM ALBUMIN","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"LEU A 214;LEU A 318;ALA A 317;ILE A 316;ALA A 366","None","1.19A","2bxpA-2yfhA:undetectable","2bxpA-2yfhA:20.93"],["2NYR_B_SVRB401_4","NAD-DEPENDENT DEACETYLASE SIRTUIN-5","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"ALA A 341;ALA A 371;ALA A 370;VAL A 426","None","0.93A","2nyrB-2yfhA:undetectable","2nyrB-2yfhA:21.80"],["2PGZ_D_COCD401_1","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"TYR A 189;TYR A 181;GLN A 180;ILE A 184","None","1.38A","2pgzD-2yfhA:undetectable;2pgzE-2yfhA:undetectable","2pgzD-2yfhA:18.79;2pgzE-2yfhA:18.79"],["2WD9_A_IBPA1570_1","ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"LEU A 101;VAL A  80;GLY A 108;ARG A  94","None","0.76A","2wd9A-2yfhA:4.1","2wd9A-2yfhA:20.95"],["2WD9_B_IBPB1570_1","ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"LEU A 101;VAL A  80;GLY A 108;ARG A  94","None","0.75A","2wd9B-2yfhA:3.9","2wd9B-2yfhA:20.95"],["3CZH_A_D2VA602_1","CYTOCHROME P450 2R1","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"PHE A 365;VAL A 426;ALA A 429;ALA A 343;VAL A 342","None","1.12A","3czhA-2yfhA:undetectable","3czhA-2yfhA:20.75"],["3KO0_E_TFPE201_1","PROTEIN S100-A4;PROTEIN S100-A4","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"PHE A 434;GLY A 433;PHE A 113;PHE A 109","None","0.93A","3ko0D-2yfhA:undetectable;3ko0E-2yfhA:0.6","3ko0D-2yfhA:12.47;3ko0E-2yfhA:12.47"],["3KO0_O_TFPO201_1","PROTEIN S100-A4;PROTEIN S100-A4","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"PHE A 109;PHE A 434;GLY A 433;PHE A 113","None","0.97A","3ko0O-2yfhA:0.3;3ko0Q-2yfhA:undetectable","3ko0O-2yfhA:12.47;3ko0Q-2yfhA:12.47"],["3KO0_Q_TFPQ201_1","PROTEIN S100-A4;PROTEIN S100-A4","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"PHE A 434;GLY A 433;PHE A 113;PHE A 109","None","0.98A","3ko0O-2yfhA:0.3;3ko0Q-2yfhA:undetectable","3ko0O-2yfhA:12.47;3ko0Q-2yfhA:12.47"],["3NMU_F_SAMF228_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE;NOP5\/NOP56 RELATED PROTEIN","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"GLY A 238;ALA A 260;SER A 235;ASP A 262;GLN A 308","None","1.28A","3nmuA-2yfhA:undetectable;3nmuF-2yfhA:undetectable","3nmuA-2yfhA:23.36;3nmuF-2yfhA:21.69"],["3ROX_A_TEPA266_1","APOLIPOPROTEIN A-I-BINDING PROTEIN","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"ALA A 394;VAL A 397;ASP A 398;LEU A 401","None","0.69A","3roxA-2yfhA:6.1","3roxA-2yfhA:19.78"],["3TM4_B_SAMB401_0","TRNA (GUANINE N2-)-METHYLTRANSFERASE TRM14","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"ALA A 343;LEU A 425;GLY A 368;ALA A 377;LEU A 401","None","1.20A","3tm4B-2yfhA:4.8","3tm4B-2yfhA:23.89"],["3UT5_D_LOCD502_1","TUBULIN BETA CHAIN","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"ALA A 220;LEU A 222;ALA A 341;ALA A 366;ILE A 316","None","0.99A","3ut5D-2yfhA:undetectable","3ut5D-2yfhA:21.98"],["3VAQ_A_ADNA401_2","PUTATIVE ADENOSINE KINASE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"LEU A 364;ALA A 366;PHE A 217;ASN A 424","None","1.46A","3vaqA-2yfhA:undetectable","3vaqA-2yfhA:21.24"],["3VAS_A_ADNA401_2","PUTATIVE ADENOSINE KINASE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"LEU A 364;ALA A 366;PHE A 217;ASN A 424","None","1.49A","3vasA-2yfhA:undetectable","3vasA-2yfhA:21.35"],["4F84_A_SAMA501_0","GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"GLY A 127;GLY A  91;VAL A  80;GLN A 111;VAL A  99","None","1.18A","4f84A-2yfhA:4.3","4f84A-2yfhA:22.36"],["4FE1_A_PQNA846_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;PHOTOSYSTEM I REACTION CENTER SUBUNIT IX","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"PHE A 229;ALA A 220;LEU A 222;GLY A 228;ALA A 354","None","1.16A","4fe1A-2yfhA:undetectable;4fe1J-2yfhA:undetectable","4fe1A-2yfhA:22.49;4fe1J-2yfhA:8.14"],["4H2F_A_ADNA601_1","5'-NUCLEOTIDASE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"ARG A 206;GLY A 202;ARG A 198;GLY A 195;PHE A 200","None","0.98A","4h2fA-2yfhA:undetectable","4h2fA-2yfhA:23.63"],["4H2G_A_ADNA603_1","5'-NUCLEOTIDASE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"ARG A 206;GLY A 202;ARG A 198;GLY A 195;PHE A 200","None","0.93A","4h2gA-2yfhA:undetectable","4h2gA-2yfhA:23.63"],["4KOU_A_C04A206_1","UNCHARACTERIZED PROTEIN","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"PHE A  61;TYR A 153;PHE A 148;ARG A  79;LEU A  93","None","1.33A","4kouA-2yfhA:0.0","4kouA-2yfhA:16.63"],["4L6V_1_PQN12001_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;FUSION PROTEIN OF PHOTOSYSTEM I SUBUNIT III AND SUBUNIT IX","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"PHE A 229;ALA A 220;LEU A 222;GLY A 228;ALA A 354","None","1.08A","4l6v1-2yfhA:undetectable;4l6v6-2yfhA:undetectable","4l6v1-2yfhA:21.30;4l6v6-2yfhA:13.88"],["4L6V_A_PQNA2001_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;FUSION PROTEIN OF PHOTOSYSTEM I SUBUNIT III AND SUBUNIT IX","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"PHE A 229;ALA A 220;LEU A 222;GLY A 228;ALA A 331","None","1.26A","4l6va-2yfhA:undetectable;4l6vf-2yfhA:undetectable","4l6va-2yfhA:21.30;4l6vf-2yfhA:13.88"],["4L6V_A_PQNA2001_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;FUSION PROTEIN OF PHOTOSYSTEM I SUBUNIT III AND SUBUNIT IX","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"PHE A 229;ALA A 220;LEU A 222;GLY A 228;ALA A 354","None","1.10A","4l6va-2yfhA:undetectable;4l6vf-2yfhA:undetectable","4l6va-2yfhA:21.30;4l6vf-2yfhA:13.88"],["4L78_A_ACTA1327_0","PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"VAL A  23;THR A  25;GLU A  27;GLU A  28","None","1.42A","4l78A-2yfhA:undetectable","4l78A-2yfhA:16.99"],["4LUF_A_ACTA605_0","SERUM ALBUMIN","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"ALA A 366;HIS A 409;PHE A 217;LEU A 222","None","1.31A","4lufA-2yfhA:0.0","4lufA-2yfhA:20.84"],["4LUH_A_ACTA609_0","SERUM ALBUMIN","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"ALA A 366;HIS A 409;PHE A 217;LEU A 222","None","1.33A","4luhA-2yfhA:0.0","4luhA-2yfhA:20.84"],["4QWP_A_GCSA301_1","CHITOSANASE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",3,"TYR A 181;GLY A 157;PRO A 158","None","0.65A","4qwpA-2yfhA:undetectable","4qwpA-2yfhA:20.79"],["4XP1_A_LDPA708_1","DOPAMINE TRANSPORTER, ISOFORM B","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"ASP A 398;ALA A 246;VAL A 215;TYR A 216;GLY A 211","None","1.13A","4xp1A-2yfhA:undetectable","4xp1A-2yfhA:21.54"],["4Z4G_A_IPHA905_0","PROTEIN ARGONAUTE-2","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"ASP A 327;ALA A 331;THR A 351;THR A 350","None","1.34A","4z4gA-2yfhA:3.9","4z4gA-2yfhA:18.76"],["5A06_B_SORB1342_0","ALDOSE-ALDOSE OXIDOREDUCTASE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"ILE A  86;GLU A  56;GLY A 124;GLY A 123","None","0.86A","5a06B-2yfhA:3.2","5a06B-2yfhA:22.27"],["5HG0_A_SAMA301_0","PANTOTHENATE SYNTHETASE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"GLY A 213;LEU A 401;GLY A 375;THR A 210;LEU A 214","None","1.24A","5hg0A-2yfhA:undetectable","5hg0A-2yfhA:19.30"],["5IK1_A_CAMA503_0","CAMPHOR 5-MONOOXYGENASE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",5,"GLY A 165;THR A 194;VAL A 162;ASP A 161;ILE A 156","None","1.37A","5ik1A-2yfhA:undetectable","5ik1A-2yfhA:23.71"],["5JSD_A_1GNA615_1","PHIAB6 TAILSPIKE;PHIAB6 TAILSPIKE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",3,"TYR A  43;TYR A 419;GLN A 435","None","1.15A","5jsdA-2yfhA:undetectable;5jsdB-2yfhA:undetectable","5jsdA-2yfhA:21.79;5jsdB-2yfhA:21.79"],["5JSD_B_1GNB606_1","PHIAB6 TAILSPIKE;PHIAB6 TAILSPIKE","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",3,"TYR A  43;TYR A 419;GLN A 435","None","1.16A","5jsdB-2yfhA:undetectable;5jsdC-2yfhA:undetectable","5jsdB-2yfhA:21.79;5jsdC-2yfhA:21.79"],["5VLM_B_CVIB301_1","REGULATORY PROTEIN TETR","2yfh","GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE","Escherichia coli;[Clostridium] symbiosum",4,"GLY A  84;ARG A  79;ASP A 161;ASP A 115","None","1.03A","5vlmB-2yfhA:undetectable","5vlmB-2yfhA:18.18"]]