SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yhg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		3 / 3 TRP A 872
ARG A 766
THR A 913
 None
CL  A1935 (-4.7A)
None
 1.00A 1df7A-2yhgA:
0.8		 1df7A-2yhgA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 GLU A 795
GLY A 683
ILE A 807
GLY A 764
ILE A 800
 None
 1.10A 1q8jB-2yhgA:
undetectable		 1q8jB-2yhgA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AXN_A_EDTA737_0
(6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
PHOSPHATASE 3
(6PF-2-K/FRU-
2,6-P2ASE
BRAIN/PLACENTA-TYPE
ISOZYME) (IPFK-2)
[INCLUDES: 6-
PHOSPHOFRUCTO-2-KINA
SE (EC 2.7.1.105)
FRUCTOSE-2,6-BISPHO
SPHATASE (EC
3.1.3.46)])		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 THR A 652
GLY A 649
ARG A 702
ALA A 687
TYR A 700
 None
 1.38A 2axnA-2yhgA:
undetectable		 2axnA-2yhgA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 7 SER A 604
LEU A 602
THR A 598
PRO A 597
 None
 0.98A 2ddwB-2yhgA:
undetectable		 2ddwB-2yhgA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 4 ASP A 685
ASP A 617
ASP A 532
GLY A 609
 None
EDO  A1942 (-2.9A)
CA  A1934 (-3.1A)
None
 1.25A 2igtC-2yhgA:
2.2		 2igtC-2yhgA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 6 ARG A 814
ASN A 749
ASN A 917
LEU A 868
 BTB  A1945 (-3.9A)
BTB  A1945 (-3.7A)
None
None
 1.25A 2nyrA-2yhgA:
4.1		 2nyrA-2yhgA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 VAL A 548
LEU A 745
ASP A 810
PHE A 811
LEU A 716
 None
None
BTB  A1945 (-2.7A)
None
None
 0.81A 2oipA-2yhgA:
undetectable		 2oipA-2yhgA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 VAL A 548
LEU A 745
ASP A 810
PHE A 811
LEU A 716
 None
None
BTB  A1945 (-2.7A)
None
None
 0.88A 2oipC-2yhgA:
undetectable		 2oipC-2yhgA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 5 LEU A 912
ALA A 895
ILE A 887
SER A 890
 None
 1.11A 2othA-2yhgA:
undetectable		 2othA-2yhgA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		3 / 3 ARG A 802
ASN A 921
THR A 913
 EDO  A1943 ( 4.0A)
None
None
 0.82A 2q63A-2yhgA:
undetectable		 2q63A-2yhgA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ARG A 526
ALA A 633
ILE A 605
ILE A 630
ALA A 644
 None
 1.19A 2qhfA-2yhgA:
undetectable		 2qhfA-2yhgA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 PHE A 596
ALA A 593
TYR A 553
VAL A 527
LEU A 602
 None
 1.30A 2rctA-2yhgA:
undetectable		 2rctA-2yhgA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 LEU A 745
GLY A 762
GLY A 765
GLY A 764
PRO A 742
 None
MG  A1939 (-3.9A)
MG  A1939 (-3.8A)
None
None
 1.06A 3axzA-2yhgA:
undetectable		 3axzA-2yhgA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 8 ILE A 559
ASN A 651
THR A 569
GLY A 626
 None
 0.72A 3dcjB-2yhgA:
3.7		 3dcjB-2yhgA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 4 ILE A 578
GLN A 541
ILE A 558
LEU A 716
 None
 1.29A 3dzyD-2yhgA:
undetectable		 3dzyD-2yhgA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 VAL A 548
LEU A 745
ASP A 810
PHE A 811
LEU A 716
 None
None
BTB  A1945 (-2.7A)
None
None
 0.73A 3hj3D-2yhgA:
undetectable		 3hj3D-2yhgA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 4 GLY A 612
TYR A 613
GLY A 614
ASP A 685
 None
 1.32A 3kl3A-2yhgA:
undetectable		 3kl3A-2yhgA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 8 ASP A 539
ASP A 538
GLY A 739
TYR A 735
 CA  A1934 (-2.2A)
CA  A1934 ( 4.7A)
None
None
 0.79A 3s3mA-2yhgA:
undetectable		 3s3mA-2yhgA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 7 LEU A 676
ALA A 633
GLY A 557
ILE A 559
 None
 0.86A 3spkB-2yhgA:
undetectable		 3spkB-2yhgA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 5 SER A 799
ILE A 807
GLY A 764
PRO A 742
 MG  A1939 (-4.4A)
None
None
None
 1.04A 3uboB-2yhgA:
undetectable		 3uboB-2yhgA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 LEU A 691
LEU A 669
ILE A 653
THR A 663
VAL A 634
 None
 1.22A 4f4dB-2yhgA:
3.1		 4f4dB-2yhgA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 9 GLY A 765
GLY A 764
ASN A 753
GLU A 798
ILE A 807
 MG  A1939 (-3.8A)
None
None
None
None
 1.34A 4fgjA-2yhgA:
2.3
4fgjB-2yhgA:
3.9		 4fgjA-2yhgA:
19.85
4fgjB-2yhgA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ILE A 807
GLY A 765
GLY A 764
ASN A 753
GLU A 798
 None
MG  A1939 (-3.8A)
None
None
None
 1.41A 4fglA-2yhgA:
3.9
4fglB-2yhgA:
3.8		 4fglA-2yhgA:
19.85
4fglB-2yhgA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 8 GLY A 683
GLY A 688
LEU A 691
VAL A 678
 None
 0.92A 4fgzA-2yhgA:
undetectable		 4fgzA-2yhgA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 5 ALA A 743
HIS A 529
GLN A 546
TYR A 553
 None
 1.48A 4gboB-2yhgA:
undetectable		 4gboB-2yhgA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 6 ASP A 862
ASP A 916
ASN A 921
ASP A 864
 CA  A1936 (-2.2A)
CA  A1936 (-3.1A)
None
CA  A1936 (-3.4A)
 1.07A 4mdbA-2yhgA:
undetectable		 4mdbA-2yhgA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		3 / 3 ARG A 677
TRP A 643
ILE A 699
 None
 0.73A 4mwxA-2yhgA:
undetectable		 4mwxA-2yhgA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		3 / 3 SER A 542
ASP A 539
GLN A 684
 None
CA  A1934 (-2.2A)
CA  A1934 ( 4.3A)
 0.85A 4oltA-2yhgA:
undetectable
4oltB-2yhgA:
undetectable		 4oltA-2yhgA:
21.79
4oltB-2yhgA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		3 / 3 GLN A 684
SER A 542
ASP A 539
 CA  A1934 ( 4.3A)
None
CA  A1934 (-2.2A)
 0.86A 4qwpA-2yhgA:
undetectable
4qwpB-2yhgA:
undetectable		 4qwpA-2yhgA:
21.79
4qwpB-2yhgA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 PHE A 596
ALA A 593
TYR A 553
VAL A 527
LEU A 602
 None
 1.30A 4qynA-2yhgA:
undetectable		 4qynA-2yhgA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 LEU A 745
GLY A 762
GLY A 765
GLY A 764
PRO A 742
 None
MG  A1939 (-3.9A)
MG  A1939 (-3.8A)
None
None
 1.02A 4yvgA-2yhgA:
undetectable		 4yvgA-2yhgA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 ASP A 685
ALA A 654
VAL A 657
GLY A 609
THR A 561
 None
 1.25A 5igiA-2yhgA:
undetectable		 5igiA-2yhgA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		3 / 3 TYR A 707
TYR A 730
SER A 542
 None
 0.98A 5iktB-2yhgA:
0.5		 5iktB-2yhgA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 8 GLU A 552
GLY A 751
PRO A 750
TRP A 763
 BTB  A1945 ( 3.8A)
None
BTB  A1945 ( 4.7A)
BTB  A1945 (-4.9A)
 1.08A 5kgpA-2yhgA:
undetectable		 5kgpA-2yhgA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 8 GLU A 552
GLY A 751
PRO A 750
TRP A 763
 BTB  A1945 ( 3.8A)
None
BTB  A1945 ( 4.7A)
BTB  A1945 (-4.9A)
 1.10A 5kgpB-2yhgA:
undetectable		 5kgpB-2yhgA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 ALA A 585
PHE A 596
SER A 590
LEU A 543
VAL A 729
 None
 1.26A 5uanB-2yhgA:
undetectable		 5uanB-2yhgA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 12 LEU A 745
GLY A 762
GLY A 765
GLY A 764
PRO A 742
 None
MG  A1939 (-3.9A)
MG  A1939 (-3.8A)
None
None
 1.00A 5wyqB-2yhgA:
undetectable		 5wyqB-2yhgA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 6 SER A 854
ALA A 893
SER A 894
SER A 858
 None
 0.87A 6bocA-2yhgA:
undetectable
6bocB-2yhgA:
undetectable
6bocC-2yhgA:
undetectable
6bocD-2yhgA:
undetectable		 6bocA-2yhgA:
5.63
6bocB-2yhgA:
5.63
6bocC-2yhgA:
5.63
6bocD-2yhgA:
5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 6 SER A 858
SER A 854
ALA A 893
SER A 894
 None
 0.88A 6bocA-2yhgA:
undetectable
6bocB-2yhgA:
undetectable
6bocC-2yhgA:
undetectable
6bocD-2yhgA:
undetectable		 6bocA-2yhgA:
5.63
6bocB-2yhgA:
5.63
6bocC-2yhgA:
5.63
6bocD-2yhgA:
5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		3 / 3 ALA A 654
PHE A 695
GLN A 661
 None
 0.77A 6eceA-2yhgA:
undetectable		 6eceA-2yhgA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		4 / 7 ARG A 545
TYR A 715
HIS A 808
TRP A 709
 None
 1.24A 6g2pA-2yhgA:
undetectable		 6g2pA-2yhgA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN1_A_LLLA302_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE)		 2yhg CELLULOSE-BINDING
PROTEIN
(Saccharophagus
degradans) 		5 / 10 ASP A 532
ASP A 538
GLY A 648
ASP A 576
THR A 572
 CA  A1934 (-3.1A)
CA  A1934 ( 4.7A)
CA  A1934 ( 4.4A)
None
None
 1.47A 6mn1A-2yhgA:
0.8		 6mn1A-2yhgA:
11.34