SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 10 LEU A  43
LEU A  36
ILE A 321
PHE A  19
ILE A  48
 None
 1.36A 1i18A-2yijA:
undetectable
1i18B-2yijA:
undetectable		 1i18A-2yijA:
12.71
1i18B-2yijA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 CYH A 233
THR A 231
SER A 152
LEU A  43
 None
 0.97A 1qcaA-2yijA:
undetectable		 1qcaA-2yijA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 ARG A 147
TYR A 223
LYS A 222
 None
 0.95A 1uujB-2yijA:
undetectable		 1uujB-2yijA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 12 LEU A 144
TYR A  50
ILE A  47
VAL A 348
LEU A  39
 None
 0.98A 1vptA-2yijA:
undetectable		 1vptA-2yijA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 10 LEU A  39
LEU A  36
LEU A 295
LEU A  43
ARG A  44
 None
 1.13A 2riwA-2yijA:
undetectable
2riwB-2yijA:
undetectable		 2riwA-2yijA:
21.40
2riwB-2yijA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 10 LEU A  39
LEU A  36
LEU A 295
LEU A  43
ARG A  44
 None
 1.12A 2xn6A-2yijA:
undetectable
2xn6B-2yijA:
undetectable		 2xn6A-2yijA:
19.43
2xn6B-2yijA:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 GLY A 343
ILE A 321
THR A 297
LEU A 345
 None
 0.89A 2xrhA-2yijA:
undetectable		 2xrhA-2yijA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 6 ILE A 193
ILE A 232
LEU A 114
PHE A 113
 None
 1.09A 3adsA-2yijA:
undetectable		 3adsA-2yijA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 5 PRO A 305
THR A 351
VAL A 348
GLY A 347
 None
 1.15A 3elzA-2yijA:
undetectable		 3elzA-2yijA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 VAL A 212
VAL A 216
LEU A 219
VAL A 228
 None
 0.79A 3hs6B-2yijA:
undetectable		 3hs6B-2yijA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 12 PHE A 282
THR A 247
PHE A 113
ILE A 304
ALA A 273
 None
 1.15A 3nxuB-2yijA:
undetectable		 3nxuB-2yijA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 8 THR A 297
ARG A 296
GLY A 234
PHE A 272
 None
 1.03A 3tzfB-2yijA:
undetectable		 3tzfB-2yijA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 LEU A 289
ALA A 246
VAL A 271
ILE A 292
 None
 0.95A 3wsjB-2yijA:
undetectable		 3wsjB-2yijA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 MET A 396
ASP A 408
SER A  67
GLU A 405
 None
 1.30A 4aq7A-2yijA:
undetectable		 4aq7A-2yijA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CD2_A_FOLA207_0
(DIHYDROFOLATE
REDUCTASE)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 12 ALA A  54
PHE A  19
LEU A 144
ARG A 146
TYR A 132
 None
 1.17A 4cd2A-2yijA:
undetectable		 4cd2A-2yijA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 VAL A 212
VAL A 216
LEU A 219
VAL A 228
 None
 0.77A 4e1gB-2yijA:
undetectable		 4e1gB-2yijA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 8 VAL A 212
VAL A 151
ILE A 232
LEU A 244
 None
 0.84A 4jq1B-2yijA:
undetectable		 4jq1B-2yijA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 6 VAL A 212
VAL A 151
ILE A 232
LEU A 244
 None
 0.87A 4l1wB-2yijA:
undetectable		 4l1wB-2yijA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 12 ASP A 279
VAL A 315
PHE A 177
SER A 280
THR A 247
 None
 1.25A 4mm4A-2yijA:
undetectable		 4mm4A-2yijA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 12 ASP A 279
VAL A 315
PHE A 177
SER A 280
THR A 247
 None
 1.28A 4mm4B-2yijA:
undetectable		 4mm4B-2yijA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.80A 5bs8A-2yijA:
undetectable
5bs8C-2yijA:
undetectable
5bs8D-2yijA:
undetectable		 5bs8A-2yijA:
22.20
5bs8C-2yijA:
22.20
5bs8D-2yijA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.77A 5btaA-2yijA:
undetectable
5btaC-2yijA:
undetectable
5btaD-2yijA:
undetectable		 5btaA-2yijA:
22.12
5btaC-2yijA:
22.12
5btaD-2yijA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 6 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.80A 5btaA-2yijA:
undetectable
5btaB-2yijA:
undetectable
5btaC-2yijA:
undetectable		 5btaA-2yijA:
22.12
5btaB-2yijA:
20.43
5btaC-2yijA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 6 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.78A 5btcA-2yijA:
undetectable
5btcC-2yijA:
undetectable
5btcD-2yijA:
undetectable		 5btcA-2yijA:
22.12
5btcC-2yijA:
22.12
5btcD-2yijA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 6 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.83A 5btcA-2yijA:
undetectable
5btcB-2yijA:
undetectable
5btcC-2yijA:
undetectable		 5btcA-2yijA:
22.12
5btcB-2yijA:
20.43
5btcC-2yijA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.81A 5btdA-2yijA:
undetectable
5btdB-2yijA:
undetectable
5btdC-2yijA:
undetectable		 5btdA-2yijA:
22.20
5btdB-2yijA:
20.43
5btdC-2yijA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.78A 5btdA-2yijA:
undetectable
5btdC-2yijA:
undetectable
5btdD-2yijA:
undetectable		 5btdA-2yijA:
22.20
5btdC-2yijA:
22.20
5btdD-2yijA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.80A 5btfA-2yijA:
undetectable
5btfB-2yijA:
undetectable
5btfC-2yijA:
undetectable		 5btfA-2yijA:
22.12
5btfB-2yijA:
20.43
5btfC-2yijA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.79A 5btfA-2yijA:
undetectable
5btfC-2yijA:
undetectable
5btfD-2yijA:
undetectable		 5btfA-2yijA:
22.12
5btfC-2yijA:
22.12
5btfD-2yijA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 6 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.87A 5btgA-2yijA:
undetectable
5btgB-2yijA:
undetectable
5btgC-2yijA:
undetectable		 5btgA-2yijA:
22.20
5btgB-2yijA:
20.43
5btgC-2yijA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 7 ARG A 218
GLY A 217
THR A  98
GLU A 215
 None
 0.88A 5btgA-2yijA:
undetectable
5btgC-2yijA:
undetectable
5btgD-2yijA:
undetectable		 5btgA-2yijA:
22.20
5btgC-2yijA:
22.20
5btgD-2yijA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 8 ALA A 246
THR A 247
VAL A 250
VAL A 315
 None
 0.86A 5ecnD-2yijA:
undetectable		 5ecnD-2yijA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 12 ILE A 232
ALA A 269
GLY A 131
GLY A 234
VAL A 212
 None
 1.05A 5i71A-2yijA:
undetectable		 5i71A-2yijA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 12 ILE A 232
ALA A 269
GLY A 131
GLY A 234
VAL A 212
 None
 1.06A 5i75A-2yijA:
undetectable		 5i75A-2yijA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 LEU A 144
TYR A  50
SER A  27
 None
 0.84A 5iktA-2yijA:
undetectable		 5iktA-2yijA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 ASP A 279
ASN A 172
PHE A 286
 None
 0.80A 5jglB-2yijA:
undetectable		 5jglB-2yijA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 VAL A 151
VAL A 133
GLN A 211
 None
 0.67A 5qglA-2yijA:
undetectable		 5qglA-2yijA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 VAL A 151
VAL A 133
GLN A 211
 None
 0.69A 5qguA-2yijA:
undetectable		 5qguA-2yijA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 VAL A 151
VAL A 133
GLN A 211
 None
 0.71A 5qgvA-2yijA:
undetectable		 5qgvA-2yijA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 VAL A 151
VAL A 133
GLN A 211
 None
 0.71A 5qgwA-2yijA:
undetectable		 5qgwA-2yijA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 VAL A 151
VAL A 133
GLN A 211
 None
 0.72A 5qgxA-2yijA:
undetectable		 5qgxA-2yijA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 VAL A 151
VAL A 133
GLN A 211
 None
 0.71A 5qh4A-2yijA:
undetectable		 5qh4A-2yijA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 VAL A 151
VAL A 133
GLN A 211
 None
 0.71A 5qh9A-2yijA:
undetectable		 5qh9A-2yijA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 VAL A 151
VAL A 133
GLN A 211
 None
 0.70A 5qhcA-2yijA:
undetectable		 5qhcA-2yijA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 VAL A 151
VAL A 133
GLN A 211
 None
 0.72A 5qheA-2yijA:
undetectable		 5qheA-2yijA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		4 / 8 GLY A 155
GLY A 238
LEU A 241
ALA A 240
 None
 0.62A 5vw5A-2yijA:
undetectable		 5vw5A-2yijA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 12 GLU A 215
VAL A 216
HIS A  49
PHE A  81
GLY A 140
 None
 1.34A 5xioA-2yijA:
undetectable		 5xioA-2yijA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 MET A  35
ASP A  42
ARG A 146
 None
 1.17A 5z6jA-2yijA:
undetectable		 5z6jA-2yijA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		3 / 3 TYR A  95
LEU A  86
ASP A  59
 None
 0.89A 5zv2B-2yijA:
undetectable		 5zv2B-2yijA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2yij PHOSPHOLIPASE
A1-IIGAMMA
(Arabidopsis
thaliana) 		5 / 10 ASP A 148
SER A 229
TYR A  50
SER A 274
VAL A 294
 None
 1.43A 6hu9L-2yijA:
undetectable
6hu9P-2yijA:
undetectable
6hu9T-2yijA:
undetectable		 6hu9L-2yijA:
22.71
6hu9P-2yijA:
17.18
6hu9T-2yijA:
9.64