SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yjn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		4 / 5 HIS A  88
SER A  96
LEU A  97
GLY B  42
 None
 0.99A 1a4lB-2yjnA:
undetectable		 1a4lB-2yjnA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		4 / 8 ILE A 228
PHE A  44
LEU A 433
VAL A 244
 None
 0.86A 1fslA-2yjnA:
undetectable		 1fslA-2yjnA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		4 / 8 ILE A 228
PHE A  44
LEU A 433
VAL A 244
 None
 0.78A 1fslB-2yjnA:
undetectable		 1fslB-2yjnA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 11 GLY A 253
PRO A 254
HIS A 330
GLY A 346
ILE A 353
 None
 1.05A 1jzsA-2yjnA:
undetectable		 1jzsA-2yjnA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		4 / 7 TYR A 251
THR A 305
THR A 273
SER A 347
 None
 1.09A 1tv8B-2yjnA:
undetectable		 1tv8B-2yjnA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU B  39
GLY B 113
ALA B 114
GLY B  30
ILE B  36
 None
 0.90A 2avvD-2yjnB:
undetectable		 2avvD-2yjnB:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 MET B  35
ARG B  37
ILE B  36
SER B 197
GLY A  87
 None
 1.23A 2lbdA-2yjnB:
undetectable		 2lbdA-2yjnB:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU B  39
GLY B 113
ALA B 114
GLY B  30
ILE B  36
 None
 0.96A 2nmyB-2yjnB:
undetectable		 2nmyB-2yjnB:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 THR B  88
ALA B 299
ALA B 298
LEU B 196
TYR B  50
 None
 1.15A 2nyrA-2yjnB:
undetectable		 2nyrA-2yjnB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB926_0
(FERROCHELATASE)		 2yjn GLYCOSYLTRANSFERASE
DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea;
Saccharopolyspor
a
erythraea) 		5 / 10 MET B  35
LEU B  39
ILE A  90
PRO A 200
GLY A 114
 None
 1.42A 2qd4B-2yjnB:
0.0		 2qd4B-2yjnB:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU B  39
GLY B 113
ALA B 114
GLY B  30
ILE B  36
 None
 0.91A 2rkfA-2yjnB:
undetectable		 2rkfA-2yjnB:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 MET B  35
THR A 117
PHE A  82
ARG B  77
GLY B  44
 None
 1.44A 3aobC-2yjnB:
undetectable		 3aobC-2yjnB:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 MET B  35
THR A 117
PHE A  82
ARG B  77
GLY B  44
 None
 1.50A 3aodC-2yjnB:
undetectable		 3aodC-2yjnB:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		4 / 6 ASP B  60
HIS B 270
HIS B 266
ASP B 233
 None
 1.19A 3c0zC-2yjnB:
undetectable		 3c0zC-2yjnB:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		4 / 5 PRO A  39
THR A 243
VAL A 244
GLY A 245
 None
 0.92A 3elzA-2yjnA:
undetectable		 3elzA-2yjnA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 ALA A 156
ALA A 157
LEU A 132
ILE A  63
LEU A  37
 None
 0.99A 3h0aA-2yjnA:
undetectable		 3h0aA-2yjnA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		3 / 3 ARG A  95
ASP A 366
ASP A 363
 None
 0.81A 3jb3A-2yjnA:
undetectable		 3jb3A-2yjnA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU B  39
GLY B 113
ALA B 114
GLY B  30
ILE B  36
 None
 0.91A 3ndtC-2yjnB:
undetectable		 3ndtC-2yjnB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		4 / 6 ARG B 273
THR B 102
ALA B 129
ALA B 128
 None
 1.24A 3ns1C-2yjnB:
undetectable		 3ns1C-2yjnB:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		5 / 9 LEU B  39
GLY B 113
ALA B 114
GLY B  30
ILE B  36
 None
 0.91A 3oxvA-2yjnB:
undetectable		 3oxvA-2yjnB:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		5 / 9 LEU B  39
GLY B 113
ALA B 114
GLY B  30
ILE B  36
 None
 0.93A 3oxvC-2yjnB:
undetectable		 3oxvC-2yjnB:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2yjn GLYCOSYLTRANSFERASE
DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea;
Saccharopolyspor
a
erythraea) 		3 / 3 ARG B  77
HIS A  88
TYR B  43
 None
 1.23A 4fu8A-2yjnB:
undetectable		 4fu8A-2yjnB:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2yjn GLYCOSYLTRANSFERASE
DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea;
Saccharopolyspor
a
erythraea) 		3 / 3 ARG B  77
HIS A  88
TYR B  43
 None
 1.36A 4fu9A-2yjnB:
undetectable		 4fu9A-2yjnB:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		3 / 3 GLU B 261
ASP B 314
ASP B 311
 None
 0.67A 4gc9A-2yjnB:
undetectable		 4gc9A-2yjnB:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU B 192
VAL B 126
GLU B 292
THR B 277
GLY B 290
 None
 1.30A 4hvcB-2yjnB:
undetectable		 4hvcB-2yjnB:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		3 / 3 SER B  45
TYR A  93
PRO B  51
 None
 0.98A 4kahB-2yjnB:
undetectable		 4kahB-2yjnB:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		3 / 3 SER B  45
TYR A  93
PRO B  51
 None
 0.98A 4kanB-2yjnB:
undetectable		 4kanB-2yjnB:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		3 / 3 SER B  45
TYR A  93
PRO B  51
 None
 0.97A 4kbeA-2yjnB:
undetectable		 4kbeA-2yjnB:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		3 / 3 SER B  45
TYR A  93
PRO B  51
 None
 0.97A 4kbeB-2yjnB:
undetectable		 4kbeB-2yjnB:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		4 / 8 LEU A 201
LEU A 205
LEU A 209
HIS A 168
 None
 0.84A 4klaA-2yjnA:
undetectable		 4klaA-2yjnA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 VAL A 163
ALA A 161
SER A 138
SER A 128
THR A 166
 None
 0.95A 4ky8A-2yjnA:
undetectable		 4ky8A-2yjnA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 VAL A 163
ALA A 161
SER A 138
SER A 128
THR A 166
 None
 0.98A 4ky8B-2yjnA:
undetectable		 4ky8B-2yjnA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 VAL A 163
ALA A 161
SER A 138
SER A 128
THR A 166
 None
 0.99A 4ky8C-2yjnA:
2.1		 4ky8C-2yjnA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_E_MTXE603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 VAL A 163
ALA A 161
SER A 138
SER A 128
THR A 166
 None
 0.97A 4ky8E-2yjnA:
undetectable		 4ky8E-2yjnA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		4 / 8 VAL B 232
ASP B 233
GLY B 373
ALA B 163
 None
 0.91A 4m48A-2yjnB:
undetectable		 4m48A-2yjnB:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		4 / 8 MET B 109
GLU B  79
GLU B 292
ARG B  75
 None
 1.16A 4mj8B-2yjnB:
undetectable
4mj8C-2yjnB:
undetectable		 4mj8B-2yjnB:
16.67
4mj8C-2yjnB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		4 / 6 THR B  78
GLU B  79
THR B  80
THR B 102
 None
 1.12A 4pgfA-2yjnB:
undetectable		 4pgfA-2yjnB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		3 / 3 TRP A 150
ARG A 170
LEU A 205
 None
 0.92A 5dbyA-2yjnA:
undetectable		 5dbyA-2yjnA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		3 / 3 VAL A  73
ARG A 170
PRO A 158
 None
 0.70A 5koxA-2yjnA:
undetectable		 5koxA-2yjnA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		4 / 8 GLU B 205
VAL B 208
GLY B  30
LEU B  33
 None
 1.04A 5sxqB-2yjnB:
undetectable		 5sxqB-2yjnB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		4 / 8 GLU B 205
VAL B 208
GLY B  30
LEU B  33
 None
 0.99A 5sxtA-2yjnB:
0.5		 5sxtA-2yjnB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 2yjn DTDP-4-KETO-6-DEOXY-
HEXOSE 3,4-ISOMERASE
(Saccharopolyspor
a
erythraea) 		4 / 8 GLU B 205
VAL B 208
GLY B  30
LEU B  33
 None
 1.05A 5syjA-2yjnB:
undetectable		 5syjA-2yjnB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 PHE A 155
ILE A 228
THR A 166
ALA A 157
GLU A 151
 None
 1.22A 5vcgA-2yjnA:
undetectable		 5vcgA-2yjnA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		3 / 3 ARG A 182
ARG A 170
ARG A 180
 None
 0.98A 5vcgA-2yjnA:
undetectable		 5vcgA-2yjnA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		5 / 12 ALA A 156
ALA A 157
LEU A 132
ILE A  63
LEU A  37
 None
 0.85A 6a5yD-2yjnA:
undetectable		 6a5yD-2yjnA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		3 / 3 SER A  32
LYS A  31
SER A  30
 None
 0.77A 6az3P-2yjnA:
undetectable		 6az3P-2yjnA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		4 / 6 VAL A 397
LEU A 383
LEU A 361
HIS A 341
 None
 1.03A 6e43A-2yjnA:
undetectable		 6e43A-2yjnA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		4 / 6 VAL A 397
LEU A 383
LEU A 361
HIS A 341
 None
 1.00A 6e43B-2yjnA:
undetectable		 6e43B-2yjnA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		4 / 6 VAL A 397
LEU A 383
LEU A 361
HIS A 341
 None
 1.02A 6e43C-2yjnA:
undetectable		 6e43C-2yjnA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2yjn GLYCOSYLTRANSFERASE
(Saccharopolyspor
a
erythraea) 		4 / 6 MET A 127
ALA A  58
LEU A  59
ALA A  55
 None
 1.17A 6fosB-2yjnA:
undetectable		 6fosB-2yjnA:
10.79