SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yjt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 2yjt ATP-DEPENDENT RNA
HELICASE SRMB
(Escherichia
coli) 		4 / 7 LEU D 360
VAL D 363
GLY D 364
ILE D 336
 None
 0.80A 1p2yA-2yjtD:
undetectable		 1p2yA-2yjtD:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 2yjt ATP-DEPENDENT RNA
HELICASE SRMB
(Escherichia
coli) 		5 / 12 LEU D 232
LEU D 239
GLU D 263
LEU D 264
ARG D 260
 None
 1.31A 2bxfB-2yjtD:
undetectable		 2bxfB-2yjtD:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2yjt ATP-DEPENDENT RNA
HELICASE SRMB
(Escherichia
coli) 		3 / 3 TYR D 227
LEU D 358
ARG D 228
 None
 0.76A 3sufB-2yjtD:
undetectable		 3sufB-2yjtD:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2yjt ATP-DEPENDENT RNA
HELICASE SRMB
(Escherichia
coli) 		3 / 3 PRO D 326
MET D 325
TYR D 332
 None
 0.85A 4qa0B-2yjtD:
3.8		 4qa0B-2yjtD:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 2yjt ATP-DEPENDENT RNA
HELICASE SRMB
(Escherichia
coli) 		3 / 3 PRO D 326
MET D 325
TYR D 332
 None
 0.83A 4qa0A-2yjtD:
undetectable		 4qa0A-2yjtD:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2yjt ATP-DEPENDENT RNA
HELICASE SRMB
(Escherichia
coli) 		3 / 3 PRO D 326
MET D 325
TYR D 332
 None
 0.96A 4qa2B-2yjtD:
3.7		 4qa2B-2yjtD:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 2yjt ATP-DEPENDENT RNA
HELICASE SRMB
(Escherichia
coli) 		4 / 8 ALA D 229
ASP D 230
ASP D 231
ILE D 376
 None
 0.66A 5kr1B-2yjtD:
undetectable		 5kr1B-2yjtD:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_1
(NS3 PROTEASE)		 2yjt ATP-DEPENDENT RNA
HELICASE SRMB
(Escherichia
coli) 		5 / 9 VAL D 320
ARG D 335
ALA D 309
VAL D 307
ASP D 306
 None
 1.39A 6c2mA-2yjtD:
undetectable		 6c2mA-2yjtD:
16.57