SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yk0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 7 ALA A  60
HIS A  83
THR A  84
SER A  62
 None
 0.81A 1c9sT-2yk0A:
undetectable
1c9sU-2yk0A:
undetectable		 1c9sT-2yk0A:
6.32
1c9sU-2yk0A:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 7 ALA A  60
HIS A  83
THR A  84
SER A  62
 None
 0.78A 1gtfL-2yk0A:
undetectable
1gtfM-2yk0A:
undetectable		 1gtfL-2yk0A:
6.32
1gtfM-2yk0A:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 ALA A  60
HIS A  83
THR A  84
SER A  62
 None
 0.76A 1gtfN-2yk0A:
undetectable
1gtfO-2yk0A:
undetectable		 1gtfN-2yk0A:
6.32
1gtfO-2yk0A:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 SER A  62
ALA A  60
HIS A  83
THR A  84
 None
 0.81A 1gtnA-2yk0A:
undetectable
1gtnB-2yk0A:
undetectable		 1gtnA-2yk0A:
6.32
1gtnB-2yk0A:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 6 ASN A 160
ILE A  86
ASN A 148
THR A 151
 None
 1.07A 1h7xA-2yk0A:
undetectable		 1h7xA-2yk0A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 6 ASN A 160
ILE A  86
ASN A 148
THR A 151
 None
 1.06A 1h7xB-2yk0A:
undetectable		 1h7xB-2yk0A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 6 ASN A 160
ILE A  86
ASN A 148
THR A 151
 None
 1.05A 1h7xC-2yk0A:
undetectable		 1h7xC-2yk0A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 6 ASN A 160
ILE A  86
ASN A 148
THR A 151
 None
 1.06A 1h7xD-2yk0A:
undetectable		 1h7xD-2yk0A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_2
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION
CHIMERA OF IG
GAMMA-1 CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 5 TYR A  34
GLU A  27
TYR A 305
PRO A 302
 None
 1.39A 1i7zB-2yk0A:
undetectable		 1i7zB-2yk0A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		5 / 12 LEU A 436
ASN A 437
GLY A 439
ARG A 194
THR A 460
 None
 1.41A 1p93A-2yk0A:
undetectable		 1p93A-2yk0A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 ALA A  60
HIS A  83
THR A  84
SER A  62
 None
 0.76A 1utdB-2yk0A:
undetectable
1utdC-2yk0A:
undetectable		 1utdB-2yk0A:
6.32
1utdC-2yk0A:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 ALA A  60
HIS A  83
THR A  84
SER A  62
 None
 0.80A 1utdF-2yk0A:
undetectable
1utdG-2yk0A:
undetectable		 1utdF-2yk0A:
6.32
1utdG-2yk0A:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 ALA A  60
HIS A  83
THR A  84
SER A  62
 None
 0.78A 1utdJ-2yk0A:
undetectable
1utdK-2yk0A:
undetectable		 1utdJ-2yk0A:
6.32
1utdK-2yk0A:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 7 ARG A 314
GLU A 318
PRO A 132
ALA A 131
 None
 1.37A 2ejgB-2yk0A:
undetectable		 2ejgB-2yk0A:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		3 / 3 GLY A 243
GLY A 247
GLY A 245
 SO4  A1720 (-4.1A)
None
None
 0.39A 3bogC-2yk0A:
undetectable		 3bogC-2yk0A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 PHE A 417
ILE A 402
LEU A  26
PHE A 432
 None
 0.87A 3rqwI-2yk0A:
2.2
3rqwJ-2yk0A:
2.1		 3rqwI-2yk0A:
17.64
3rqwJ-2yk0A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_A_KANA304_1
(APH(2'')-ID)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		5 / 10 ASN A 184
SER A 191
HIS A 176
GLU A 317
GLU A 321
 None
 1.33A 3sg9A-2yk0A:
0.0		 3sg9A-2yk0A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		3 / 3 ARG A 314
ARG A 204
ASP A 207
 None
 0.88A 3wipG-2yk0A:
undetectable
3wipH-2yk0A:
undetectable		 3wipG-2yk0A:
14.65
3wipH-2yk0A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		5 / 12 ALA A 129
LEU A 313
PHE A 316
ILE A 429
LEU A 433
 None
 0.82A 4ej1B-2yk0A:
undetectable		 4ej1B-2yk0A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 7 PHE A 105
ILE A 329
PRO A 177
HIS A 441
 None
 1.11A 4g5jA-2yk0A:
undetectable		 4g5jA-2yk0A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		3 / 3 TYR A 305
HIS A 288
ARG A 280
 None
 0.81A 4htfA-2yk0A:
undetectable		 4htfA-2yk0A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 LEU A 433
PHE A 316
TRP A 319
PRO A 457
 None
 1.17A 4j7uD-2yk0A:
undetectable		 4j7uD-2yk0A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		5 / 11 LEU A  48
GLU A 254
LYS A 251
LEU A 252
LEU A 232
 None
 1.01A 4wg0K-2yk0A:
undetectable
4wg0L-2yk0A:
undetectable
4wg0M-2yk0A:
undetectable		 4wg0K-2yk0A:
2.88
4wg0L-2yk0A:
2.88
4wg0M-2yk0A:
2.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		5 / 12 ALA A 129
LEU A 313
PHE A 316
ILE A 429
LEU A 433
 None
 0.77A 4x5iA-2yk0A:
undetectable		 4x5iA-2yk0A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 6 LEU A 210
ASN A 212
PRO A 211
ARG A 253
 None
 1.11A 4yv5B-2yk0A:
undetectable		 4yv5B-2yk0A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 SER A  62
ALA A  60
HIS A  83
THR A  84
 None
 0.77A 5eezL-2yk0A:
undetectable
5eezV-2yk0A:
undetectable		 5eezL-2yk0A:
6.32
5eezV-2yk0A:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 SER A  62
ALA A  60
HIS A  83
THR A  84
 None
 0.76A 5ef1L-2yk0A:
undetectable
5ef1V-2yk0A:
undetectable		 5ef1L-2yk0A:
6.32
5ef1V-2yk0A:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 SER A  62
ALA A  60
HIS A  83
THR A  84
 None
 0.76A 5ef2L-2yk0A:
undetectable
5ef2V-2yk0A:
undetectable		 5ef2L-2yk0A:
6.32
5ef2V-2yk0A:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		5 / 12 ARG A 206
ILE A 202
GLY A 200
ILE A 199
TYR A 308
 None
 1.22A 5ifuA-2yk0A:
undetectable		 5ifuA-2yk0A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 5 TYR A  98
LYS A  95
GLU A  92
GLY A  89
 None
 1.37A 5jhdJ-2yk0A:
undetectable		 5jhdJ-2yk0A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		3 / 3 ASP A 353
ASN A 362
GLN A 363
 None
 0.66A 5k7uA-2yk0A:
undetectable		 5k7uA-2yk0A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 GLU A 322
PRO A 177
GLY A 187
ASP A 178
 None
 1.10A 5kf8A-2yk0A:
undetectable		 5kf8A-2yk0A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 GLU A 322
PRO A 177
GLY A 187
ASP A 178
 None
 0.92A 5kgpA-2yk0A:
undetectable		 5kgpA-2yk0A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 GLU A 322
PRO A 177
GLY A 187
ASP A 178
 None
 0.93A 5kgpB-2yk0A:
undetectable		 5kgpB-2yk0A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 5 LEU A 157
ARG A 253
LEU A 143
TRP A 256
 None
 1.01A 5m10A-2yk0A:
undetectable		 5m10A-2yk0A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		5 / 10 TYR A 229
LYS A 226
ILE A 228
LEU A 146
HIS A 242
 None
 1.25A 5vkqA-2yk0A:
3.3
5vkqD-2yk0A:
3.2		 5vkqA-2yk0A:
17.56
5vkqD-2yk0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		5 / 10 HIS A 242
TYR A 229
LYS A 226
ILE A 228
LEU A 146
 None
 1.21A 5vkqA-2yk0A:
3.3
5vkqB-2yk0A:
3.2		 5vkqA-2yk0A:
17.56
5vkqB-2yk0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		5 / 10 HIS A 242
TYR A 229
LYS A 226
ILE A 228
LEU A 146
 None
 1.25A 5vkqC-2yk0A:
3.2
5vkqD-2yk0A:
3.2		 5vkqC-2yk0A:
17.56
5vkqD-2yk0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 GLY A 627
ILE A 644
TRP A 579
ASP A 694
 None
 1.03A 5vlmD-2yk0A:
2.8		 5vlmD-2yk0A:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		5 / 12 ALA A  22
GLY A 439
LEU A 313
ASN A 437
PHE A 432
 None
 1.12A 5ybbA-2yk0A:
undetectable		 5ybbA-2yk0A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 ASP A 175
HIS A 441
GLU A 322
GLU A 107
 None
 1.00A 6mn4A-2yk0A:
undetectable		 6mn4A-2yk0A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 ASP A 175
HIS A 441
GLU A 322
GLU A 107
 None
 1.00A 6mn4B-2yk0A:
undetectable		 6mn4B-2yk0A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 8 ASP A 175
HIS A 441
GLU A 322
GLU A 107
 None
 1.11A 6mn4D-2yk0A:
undetectable		 6mn4D-2yk0A:
15.54