SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ylf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 2ylf PROTEIN SPIRE
HOMOLOG 1
(Homo
sapiens) 		3 / 3 LEU A 156
LEU A 153
SER A 150
 None
 0.64A 1tlmA-2ylfA:
undetectable		 1tlmA-2ylfA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 2ylf PROTEIN SPIRE
HOMOLOG 1
(Homo
sapiens) 		4 / 9 ILE A  88
ALA A  58
VAL A  61
CYH A  65
 None
 0.99A 2vufB-2ylfA:
undetectable		 2vufB-2ylfA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2ylf PROTEIN SPIRE
HOMOLOG 1
(Homo
sapiens) 		4 / 8 LEU A  69
SER A  68
VAL A  96
ALA A  99
 None
 0.96A 3ax9A-2ylfA:
undetectable		 3ax9A-2ylfA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2ylf PROTEIN SPIRE
HOMOLOG 1
(Homo
sapiens) 		4 / 4 LEU A 156
ILE A  53
TYR A 134
TYR A 217
 None
 1.43A 3vt7A-2ylfA:
undetectable		 3vt7A-2ylfA:
19.63