SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ym9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 2ym9 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		5 / 12 LEU A  87
ASN A  88
LEU A  90
ALA A  91
LEU A 105
 None
SO4  A1340 (-3.7A)
None
None
None
 0.65A 2aa6A-2ym9A:
undetectable		 2aa6A-2ym9A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2ym9 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		5 / 12 GLY A 184
GLY A 181
THR A 186
GLU A 281
LYS A 188
 None
None
None
None
GOL  A1342 (-2.4A)
 1.05A 2akeA-2ym9A:
undetectable		 2akeA-2ym9A:
21.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O01_B_DXCB1_0
(CELL INVASION
PROTEIN SIPD)		 2ym9 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		5 / 9 ASN A 104
ALA A 108
LEU A 318
ASN A 321
VAL A 325
 None
 0.66A 3o01A-2ym9A:
32.8
3o01B-2ym9A:
33.7		 3o01A-2ym9A:
88.73
3o01B-2ym9A:
88.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 2ym9 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		6 / 10 ASN A 104
ALA A 108
LEU A 318
ASN A 321
LEU A 322
VAL A 325
 None
 0.56A 3o02A-2ym9A:
32.9
3o02B-2ym9A:
32.8		 3o02A-2ym9A:
89.02
3o02B-2ym9A:
89.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 2ym9 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		5 / 12 ALA A 296
GLY A 293
SER A 292
LYS A 295
LEU A 271
 None
 1.17A 5nwuA-2ym9A:
undetectable		 5nwuA-2ym9A:
6.94