SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yma'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)
2yma PROTEIN OS-9 HOMOLOG
(Saccharomyces
cerevisiae)
3 / 3 PHE A 379
VAL A 354
TRP A 310
None
0.87A 2cc8A-2ymaA:
undetectable
2cc8A-2ymaA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)
2yma PROTEIN OS-9 HOMOLOG
(Saccharomyces
cerevisiae)
3 / 3 PHE A 379
VAL A 354
TRP A 310
None
0.85A 2ccbA-2ymaA:
undetectable
2ccbA-2ymaA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)
2yma PROTEIN OS-9 HOMOLOG
(Saccharomyces
cerevisiae)
3 / 3 PHE A 379
VAL A 354
TRP A 310
None
0.85A 2vx9A-2ymaA:
undetectable
2vx9A-2ymaA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])
2yma PROTEIN OS-9 HOMOLOG
(Saccharomyces
cerevisiae)
4 / 6 GLU A 353
LYS A 299
PRO A 291
GLU A 296
None
1.49A 4a7tF-2ymaA:
undetectable
4a7tF-2ymaA:
21.98