SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ymo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 2ymo PF12
(Plasmodium
falciparum) 		5 / 12 ASN A 258
ARG A 271
PHE A 268
GLY A 222
ASP A 180
 None
 1.49A 3a25A-2ymoA:
undetectable		 3a25A-2ymoA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 2ymo PF12
(Plasmodium
falciparum) 		4 / 8 PHE A 237
THR A 267
GLY A 178
PHE A 189
 None
 0.94A 3tzfB-2ymoA:
undetectable		 3tzfB-2ymoA:
22.19