SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yn3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		3 / 3 ALA A5215
VAL A5218
TRP A5219
 None
 0.77A 1c4dA-2yn3A:
undetectable
1c4dB-2yn3A:
undetectable		 1c4dA-2yn3A:
6.08
1c4dB-2yn3A:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		4 / 4 ASP A5296
ASP A5178
ASP A5229
GLY A5346
 CA  A6364 (-2.7A)
CA  A6363 (-2.9A)
None
None
 1.43A 2igtC-2yn3A:
undetectable		 2igtC-2yn3A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		4 / 7 TYR A5133
MET A5097
ILE A5095
ASP A5111
 None
 1.21A 2xytI-2yn3A:
undetectable		 2xytI-2yn3A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A5255
ILE A5180
ALA A5345
PRO A5186
LEU A5167
 None
CA  A6363 (-4.8A)
None
None
None
 1.22A 3a51E-2yn3A:
undetectable		 3a51E-2yn3A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		3 / 3 GLY A5137
ASP A5196
SER A5195
 CA  A6362 ( 4.4A)
CA  A6362 (-2.9A)
None
 0.71A 3brfA-2yn3A:
3.1		 3brfA-2yn3A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		4 / 6 THR A5233
ASN A5205
GLY A5206
ASP A5203
 None
 1.37A 3w9tE-2yn3A:
undetectable		 3w9tE-2yn3A:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		3 / 3 ASP A5183
ARG A5182
ASP A5170
 None
 0.87A 4fp9A-2yn3A:
undetectable		 4fp9A-2yn3A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		3 / 3 ASP A5183
ARG A5182
ASP A5170
 None
 0.84A 4fp9C-2yn3A:
undetectable		 4fp9C-2yn3A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		3 / 3 ASP A5183
ARG A5182
ASP A5170
 None
 0.83A 4fp9F-2yn3A:
undetectable		 4fp9F-2yn3A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		4 / 5 ALA A5242
ILE A5158
LEU A5156
ASN A5244
 None
 1.19A 4g19A-2yn3A:
undetectable		 4g19A-2yn3A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		4 / 5 GLU A5102
SER A5143
PRO A5080
SER A5151
 None
 1.46A 4k17B-2yn3A:
undetectable		 4k17B-2yn3A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2yn3 PUTATIVE INNER
MEMBRANE PROTEIN
(Salmonella
enterica) 		4 / 8 ALA A5103
VAL A5121
LEU A5107
ASN A5081
 None
None
None
IOD  A6361 ( 4.9A)
 0.82A 5nujA-2yn3A:
undetectable		 5nujA-2yn3A:
17.00