SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yn9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 7 ASP A1012
TYR A1032
ARG A 949
TYR A1033
 None
 1.45A 1ceaB-2yn9A:
undetectable		 1ceaB-2yn9A:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 7 ASP A1012
TYR A1032
ARG A 949
TYR A1033
 None
 1.35A 1cebA-2yn9A:
undetectable		 1cebA-2yn9A:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 7 ASP A1012
TYR A1032
ARG A 949
TYR A1033
 None
 1.36A 1cebB-2yn9A:
undetectable		 1cebB-2yn9A:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 10 ASP A 851
ASP A 779
ILE A 777
GLY A 377
PRO A 292
 None
 1.02A 1d4sA-2yn9A:
undetectable		 1d4sA-2yn9A:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 10 ASP A 851
ILE A 777
GLY A 774
GLY A 377
PRO A 292
 None
 0.88A 1sdtA-2yn9A:
undetectable		 1sdtA-2yn9A:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 10 ASP A 851
ILE A 777
GLY A 774
GLY A 377
PRO A 292
 None
 0.86A 1sdvA-2yn9A:
undetectable		 1sdvA-2yn9A:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 11 ASP A 761
GLU A 772
VAL A 768
ILE A 767
ILE A 758
 None
 1.32A 2dg3A-2yn9A:
undetectable		 2dg3A-2yn9A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 7 ALA A 611
GLY A 641
ILE A 642
PRO A 604
 None
 0.86A 2fxdB-2yn9A:
undetectable		 2fxdB-2yn9A:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 6 ASP A 628
ASP A 602
THR A 391
ASP A 385
 None
 1.08A 2j2pE-2yn9A:
undetectable
2j2pF-2yn9A:
undetectable		 2j2pE-2yn9A:
10.95
2j2pF-2yn9A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 11 ASP A 851
ASP A 779
ILE A 777
GLY A 377
PRO A 292
 None
 1.04A 2o4pA-2yn9A:
undetectable		 2o4pA-2yn9A:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		3 / 3 ARG A 950
SER A 838
TYR A1032
 None
 1.00A 2q2hA-2yn9A:
undetectable
2q2hB-2yn9A:
undetectable		 2q2hA-2yn9A:
8.03
2q2hB-2yn9A:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 LEU A 759
ASN A 763
LEU A 760
VAL A 367
THR A 769
 None
 1.22A 2q7iA-2yn9A:
undetectable		 2q7iA-2yn9A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 LEU A 759
ASN A 763
LEU A 760
VAL A 367
THR A 769
 None
 1.23A 2q7kA-2yn9A:
undetectable		 2q7kA-2yn9A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 LEU A 759
ASN A 763
LEU A 760
VAL A 367
THR A 769
 None
 1.22A 2yloA-2yn9A:
undetectable		 2yloA-2yn9A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		3 / 3 TRP A 401
VAL A 433
ARG A 480
 None
 0.86A 3b0wA-2yn9A:
undetectable		 3b0wA-2yn9A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 8 LEU A 843
ILE A 840
ARG A 846
GLY A 774
 None
 0.94A 3b9lA-2yn9A:
2.6		 3b9lA-2yn9A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 GLY A 229
GLY A 627
ASN A 393
LEU A 227
ASP A 730
 None
 1.08A 3ckkA-2yn9A:
2.7		 3ckkA-2yn9A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 10 ASP A 851
ASP A 779
ILE A 777
GLY A 377
PRO A 292
 None
 1.05A 3el9B-2yn9A:
undetectable		 3el9B-2yn9A:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 10 ASP A 851
ASP A 779
ILE A 777
GLY A 774
GLY A 377
 None
 1.00A 3em4V-2yn9A:
undetectable		 3em4V-2yn9A:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 VAL A 222
LEU A 227
SER A 226
ILE A 275
THR A 274
 None
 1.35A 3frqA-2yn9A:
1.2		 3frqA-2yn9A:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		6 / 11 GLY A 558
GLY A 555
GLU A 559
ILE A 601
ASP A 602
ILE A 636
 None
 1.46A 3grvA-2yn9A:
2.4		 3grvA-2yn9A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		6 / 11 GLY A 558
GLY A 556
GLU A 559
ILE A 601
ASP A 602
ILE A 636
 None
 1.39A 3grvA-2yn9A:
2.4		 3grvA-2yn9A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 4 PRO A 604
THR A 391
GLY A 627
THR A 702
 None
 1.16A 3ib1A-2yn9A:
undetectable		 3ib1A-2yn9A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 11 ASP A 851
ASP A 779
ILE A 777
GLY A 377
PRO A 292
 None
 1.00A 3oxxD-2yn9A:
undetectable		 3oxxD-2yn9A:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_B_GLYB509_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 4 PHE A 311
THR A 314
LEU A 307
TYR A 340
 None
 1.05A 3pgyB-2yn9A:
3.0		 3pgyB-2yn9A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 8 PHE A 402
ALA A 429
PHE A 420
THR A 472
 None
 0.96A 3t3sF-2yn9A:
0.9		 3t3sF-2yn9A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 THR A 426
PHE A 402
SER A 424
LEU A 473
PHE A 420
 None
 1.47A 3u9fD-2yn9A:
undetectable
3u9fE-2yn9A:
undetectable		 3u9fD-2yn9A:
11.98
3u9fE-2yn9A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 11 THR A 426
PHE A 402
SER A 424
LEU A 473
PHE A 420
 None
 1.42A 3u9fN-2yn9A:
undetectable
3u9fO-2yn9A:
undetectable		 3u9fN-2yn9A:
11.98
3u9fO-2yn9A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 5 LEU A 567
GLY A 591
MET A 516
PHE A 587
 None
 1.09A 3uq6B-2yn9A:
undetectable		 3uq6B-2yn9A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 LEU A 978
LEU A 809
PHE A 932
ILE A 816
ALA A 339
 None
 0.98A 3uwlB-2yn9A:
undetectable		 3uwlB-2yn9A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 LEU A 978
LEU A 809
PHE A 932
ILE A 816
ALA A 339
 None
 1.02A 3uwlD-2yn9A:
undetectable		 3uwlD-2yn9A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 LEU A 759
ASN A 763
LEU A 760
VAL A 367
THR A 769
 None
 1.26A 3zqtA-2yn9A:
undetectable		 3zqtA-2yn9A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 7 ILE A 816
PHE A 931
TYR A 799
VAL A 805
 None
 0.97A 4a97A-2yn9A:
3.2		 4a97A-2yn9A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 6 ILE A 816
PHE A 931
TYR A 799
VAL A 805
 None
 0.92A 4a97I-2yn9A:
2.8		 4a97I-2yn9A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		3 / 3 GLN A 923
ASP A 909
GLN A 913
 None
 0.93A 4aztA-2yn9A:
undetectable		 4aztA-2yn9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 8 SER A 871
ILE A 803
VAL A 318
PHE A 315
 None
 0.89A 4dx7B-2yn9A:
2.1		 4dx7B-2yn9A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 7 LEU A  89
ARG A 207
PRO A 732
VAL A 728
 None
 1.25A 4klrA-2yn9A:
2.4		 4klrA-2yn9A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 9 TRP A 427
PHE A 564
ALA A 429
LEU A 430
GLY A 596
 None
 1.27A 4l6va-2yn9A:
0.0
4l6vf-2yn9A:
undetectable		 4l6va-2yn9A:
21.48
4l6vf-2yn9A:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 8 ASP A 211
VAL A 200
GLY A 197
ALA A 178
 None
 0.93A 4m48A-2yn9A:
2.3		 4m48A-2yn9A:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 6 ASP A 385
ASP A 730
ALA A 750
ASP A 726
 None
 1.19A 4mdaA-2yn9A:
undetectable		 4mdaA-2yn9A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 6 ASP A 385
ASP A 730
ALA A 750
ASP A 726
 None
 1.21A 4mdbA-2yn9A:
undetectable		 4mdbA-2yn9A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		3 / 3 ARG A 432
ASP A 506
ARG A 428
 None
 0.94A 4mx0A-2yn9A:
undetectable		 4mx0A-2yn9A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 9 ALA A 755
ALA A 754
GLY A 744
GLY A 747
ASP A 730
 None
 1.17A 4qwuY-2yn9A:
undetectable
4qwuZ-2yn9A:
undetectable		 4qwuY-2yn9A:
12.97
4qwuZ-2yn9A:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 5 PHE A 872
PRO A 794
ALA A 873
PHE A 931
 None
 1.26A 4z4eA-2yn9A:
undetectable		 4z4eA-2yn9A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 THR A 472
GLY A 474
LEU A 473
ALA A 440
LEU A 465
 None
 0.83A 5c0oG-2yn9A:
3.6		 5c0oG-2yn9A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 8 ILE A 993
VAL A 930
GLN A 884
GLU A 885
 None
 1.15A 5dqyA-2yn9A:
undetectable		 5dqyA-2yn9A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 ALA A 440
LEU A 466
ILE A 406
GLY A 555
PHE A 564
 None
 1.20A 5eshA-2yn9A:
undetectable		 5eshA-2yn9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		3 / 3 GLY A1018
CYH A1022
CYH A1021
 None
 0.92A 5inzB-2yn9A:
undetectable		 5inzB-2yn9A:
1.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		3 / 3 THR A 702
THR A 389
LEU A 734
 None
 0.63A 5m66D-2yn9A:
3.9		 5m66D-2yn9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 ILE A 279
ILE A 758
ALA A 755
LEU A 734
ALA A 737
 None
 1.18A 5oy02-2yn9A:
undetectable		 5oy02-2yn9A:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		4 / 8 TRP A 915
THR A 916
GLN A 924
TRP A 899
 None
 1.42A 5tzoB-2yn9A:
undetectable		 5tzoB-2yn9A:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 MET A 600
ALA A 464
GLU A 470
CYH A 437
TYR A 479
 None
 1.42A 5vlmH-2yn9A:
undetectable		 5vlmH-2yn9A:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 10 ILE A 279
ILE A 758
ALA A 755
LEU A 734
ALA A 737
 None
 1.22A 5zjiB-2yn9A:
4.9		 5zjiB-2yn9A:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 TYR A 799
LEU A 809
ILE A 816
PHE A 990
THR A 823
 None
 1.30A 6djzB-2yn9A:
2.3		 6djzB-2yn9A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 SER A 169
LEU A 759
ASP A 749
ASP A 730
ILE A 166
 None
 1.38A 6dwnA-2yn9A:
undetectable		 6dwnA-2yn9A:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 9 LEU A 796
THR A 797
GLY A 874
ILE A 935
PHE A 931
 None
 1.33A 6ebpA-2yn9A:
3.2		 6ebpA-2yn9A:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1
(Sus
scrofa) 		5 / 12 THR A 152
TYR A 158
ALA A 357
LEU A 346
LEU A 370
 None
 1.27A 6ie8A-2yn9A:
1.2		 6ie8A-2yn9A:
10.97