SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ynm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_CUG2_0
(BETA-CARBONIC
ANHYDRASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 5 CYH C 103
PRO C 104
SER C 102
CYH C  42
SF4  C1413 (-2.3A)
None
SF4  C1413 (-4.7A)
SF4  C1413 (-2.3A)
1.16A 1ekjG-2ynmC:
3.9
1ekjH-2ynmC:
2.5
1ekjG-2ynmC:
19.04
1ekjH-2ynmC:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 ILE C 247
ALA C 251
ALA C 250
LEU C 232
LEU C 166
None
0.91A 1fm9A-2ynmC:
undetectable
1fm9A-2ynmC:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.96A 1hxbB-2ynmA:
undetectable
1hxbB-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 11 VAL A 147
LEU A  30
ALA A 168
THR A  45
LEU A 172
None
1.08A 1jinA-2ynmA:
undetectable
1jinA-2ynmA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 ILE C 247
ALA C 251
ALA C 250
LEU C 232
LEU C 166
None
0.93A 1k74A-2ynmC:
undetectable
1k74A-2ynmC:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 10 GLY D 305
VAL D 337
ALA D 311
ALA D 312
ILE D 301
None
1.08A 1likA-2ynmD:
undetectable
1likA-2ynmD:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 8 ILE A 238
GLY A 257
ILE A 248
SER A 241
ADP  A1300 (-3.6A)
None
None
None
0.92A 1mrjA-2ynmA:
undetectable
1mrjA-2ynmA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_B_MTXB2278_1
(PTERIDINE REDUCTASE
2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 ASP C  31
PHE C  34
LEU C 201
PRO C 194
THR C 220
None
1.40A 1mxfB-2ynmC:
2.9
1mxfB-2ynmC:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_C_MTXC3278_1
(PTERIDINE REDUCTASE
2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 ASP C  31
PHE C  34
LEU C 201
PRO C 194
THR C 220
None
1.44A 1mxfC-2ynmC:
3.1
1mxfC-2ynmC:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 4 LEU C 288
VAL C 360
CYH C 361
ALA C 366
None
1.28A 1mz9E-2ynmC:
undetectable
1mz9E-2ynmC:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 10 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.14A 1pxxA-2ynmA:
undetectable
1pxxA-2ynmA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 GLU D 227
ASN D 130
ASN D 352
GLY D 303
PHE D 179
None
1.43A 1q8jA-2ynmD:
undetectable
1q8jA-2ynmD:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus;
Prochlorococcus
marinus)
4 / 6 PRO C 104
ALA D  97
GLU D  93
GLU D  98
None
None
GOL  D1532 (-3.0A)
GOL  D1532 (-3.3A)
1.13A 1qhyA-2ynmC:
undetectable
1qhyA-2ynmC:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
4 / 7 ASP D 417
PHE D 179
SER D 403
ARG D 401
EPE  D1529 (-3.0A)
None
EPE  D1529 (-3.0A)
None
1.37A 1rqpB-2ynmD:
undetectable
1rqpB-2ynmD:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.97A 1sduA-2ynmA:
undetectable
1sduA-2ynmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.84A 1t3rB-2ynmA:
undetectable
1t3rB-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 ILE D 188
GLY D 173
ALA D 203
ILE D 202
VAL D 248
None
1.18A 1vq1A-2ynmD:
2.6
1vq1A-2ynmD:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 ILE C 247
ALA C 251
ALA C 250
LEU C 232
LEU C 166
None
1.00A 1xiuB-2ynmC:
undetectable
1xiuB-2ynmC:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 10 LEU D 349
ALA D 348
VAL D 308
ALA D 311
PHE D 300
None
1.18A 1xp0A-2ynmD:
undetectable
1xp0A-2ynmD:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 GLY C  38
LEU C  65
ASP C  81
VAL C  84
LEU C  99
None
0.94A 1zq9B-2ynmC:
undetectable
1zq9B-2ynmC:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 160
ALA A 162
LEU A 165
None
1.11A 2aylA-2ynmA:
undetectable
2aylA-2ynmA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 ILE C  64
LEU C 112
LEU C  99
CYH C  42
LEU C  35
None
None
None
SF4  C1413 (-2.3A)
None
1.15A 2bxfA-2ynmC:
undetectable
2bxfA-2ynmC:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 8 ALA C 115
ALA C  76
SER C 102
VAL C  37
None
None
SF4  C1413 (-4.7A)
None
0.80A 2bxgA-2ynmC:
undetectable
2bxgA-2ynmC:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 LEU D  26
PHE D  84
LEU D  89
LEU D  90
THR D  21
None
0.91A 2egvA-2ynmD:
undetectable
2egvA-2ynmD:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 PHE D  84
LEU D  89
LEU D  90
THR D  21
ALA D  20
None
1.08A 2egvA-2ynmD:
undetectable
2egvA-2ynmD:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 LEU D  26
PHE D  84
LEU D  89
LEU D  90
THR D  21
None
0.88A 2egvB-2ynmD:
undetectable
2egvB-2ynmD:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 PHE D  84
LEU D  89
LEU D  90
THR D  21
ALA D  20
None
1.05A 2egvB-2ynmD:
undetectable
2egvB-2ynmD:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 7 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
1.04A 2eimP-2ynmC:
undetectable
2eimW-2ynmC:
undetectable
2eimP-2ynmC:
21.92
2eimW-2ynmC:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 10 TYR D  28
GLU D 129
GLY D 132
ALA D  16
ALA D 133
None
GOL  D1530 ( 4.4A)
None
None
None
1.17A 2ej3B-2ynmD:
undetectable
2ej3B-2ynmD:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.95A 2f80A-2ynmA:
undetectable
2f80A-2ynmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.92A 2f80B-2ynmA:
undetectable
2f80B-2ynmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.99A 2f81B-2ynmA:
undetectable
2f81B-2ynmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
1.02A 2f8gA-2ynmA:
undetectable
2f8gA-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 10 GLU C  57
GLU D 358
LEU D 355
LEU D   5
TYR D 354
None
1.33A 2ha6A-2ynmC:
2.8
2ha6A-2ynmC:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_B_SCKB952_1
(ACETYLCHOLINESTERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 10 GLU C  57
GLU D 358
LEU D 355
LEU D   5
TYR D 354
None
1.32A 2ha6B-2ynmC:
undetectable
2ha6B-2ynmC:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.97A 2hs2B-2ynmA:
undetectable
2hs2B-2ynmA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
4 / 6 PHE D 300
TYR D 354
ARG D 381
LYS D 362
None
1.18A 2i30A-2ynmD:
undetectable
2i30A-2ynmD:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.96A 2ienB-2ynmA:
undetectable
2ienB-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
3 / 3 ALA D 133
GLY D 173
SER D  22
None
0.56A 2ivuA-2ynmD:
undetectable
2ivuA-2ynmD:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
1.00A 2o4lA-2ynmA:
undetectable
2o4lA-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 9 LEU A  87
ALA C  71
GLY A 125
VAL A  83
ILE A  84
None
None
SF4  A1302 (-4.1A)
None
EPE  A1298 (-4.9A)
0.90A 2o4pB-2ynmA:
undetectable
2o4pB-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 9 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.94A 2o4pB-2ynmA:
undetectable
2o4pB-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.93A 2pymA-2ynmA:
undetectable
2pymA-2ynmA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.94A 2pymB-2ynmA:
undetectable
2pymB-2ynmA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.98A 2pynA-2ynmA:
undetectable
2pynA-2ynmA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.98A 2pynB-2ynmA:
undetectable
2pynB-2ynmA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 5 LEU C 300
PRO C 299
LEU C 238
ILE C 387
None
0.75A 2qd4A-2ynmC:
undetectable
2qd4A-2ynmC:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 9 ARG D  52
LEU C 348
ASP C 349
PRO C  12
VAL C 344
None
0.93A 2r5qA-2ynmD:
undetectable
2r5qA-2ynmD:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 9 ARG D  52
LEU C 348
ASP C 349
PRO C  12
VAL C 344
None
0.94A 2r5qC-2ynmD:
undetectable
2r5qC-2ynmD:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
4 / 7 ASP D 417
PHE D 179
SER D 403
ARG D 401
EPE  D1529 (-3.0A)
None
EPE  D1529 (-3.0A)
None
1.37A 2v7uB-2ynmD:
undetectable
2v7uB-2ynmD:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 7 LEU C 304
LEU C 283
LEU C 290
PRO C 403
None
0.95A 2vq5B-2ynmC:
undetectable
2vq5B-2ynmC:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
3 / 3 ARG A 240
GLU A 255
SER A  47
None
0.92A 2xctD-2ynmA:
3.2
2xctD-2ynmA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
3 / 3 LEU C 185
ARG C 184
ILE C 187
None
0.67A 2xn5B-2ynmC:
undetectable
2xn5B-2ynmC:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 7 PRO A  67
SER A 115
ILE A  84
GLY A 126
None
None
EPE  A1298 (-4.9A)
SF4  A1302 (-3.9A)
0.97A 2y7kA-2ynmA:
undetectable
2y7kA-2ynmA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 6 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
1.02A 3abkP-2ynmC:
undetectable
3abkW-2ynmC:
undetectable
3abkP-2ynmC:
21.92
3abkW-2ynmC:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 7 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
1.04A 3ag2C-2ynmC:
undetectable
3ag2C-2ynmC:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 7 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
1.03A 3asnP-2ynmC:
undetectable
3asnW-2ynmC:
undetectable
3asnP-2ynmC:
21.92
3asnW-2ynmC:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 7 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
1.01A 3asoP-2ynmC:
undetectable
3asoW-2ynmC:
undetectable
3asoP-2ynmC:
21.92
3asoW-2ynmC:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_D_TMQD614_1
(DHFR-TS)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 10 VAL D 248
ALA D 254
ILE D 314
ILE D 389
THR D 255
None
1.15A 3clbD-2ynmD:
undetectable
3clbD-2ynmD:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.99A 3cyxA-2ynmA:
undetectable
3cyxA-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.94A 3d1xB-2ynmA:
undetectable
3d1xB-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.98A 3el1A-2ynmA:
undetectable
3el1A-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 10 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.99A 3em3B-2ynmA:
undetectable
3em3B-2ynmA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.91A 3em6B-2ynmA:
undetectable
3em6B-2ynmA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 ARG D  52
LEU C 348
ASP C 349
PRO C  12
VAL C 344
None
0.92A 3em6B-2ynmD:
undetectable
3em6B-2ynmD:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 LEU A 136
GLY A 130
ILE A  63
VAL A 156
ILE A 188
None
0.95A 3frqB-2ynmA:
undetectable
3frqB-2ynmA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_D_TMQD614_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 10 VAL D 248
ALA D 254
ILE D 314
ILE D 389
THR D 255
None
1.16A 3hbbD-2ynmD:
undetectable
3hbbD-2ynmD:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 PRO D 204
GLY D 178
SER D 390
ILE D  46
LEU D 177
None
None
None
PMR  C1414 ( 4.7A)
GOL  D1530 ( 4.6A)
1.31A 3iv6C-2ynmD:
undetectable
3iv6C-2ynmD:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.93A 3jvyA-2ynmA:
undetectable
3jvyA-2ynmA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 ALA D 203
ILE D  19
LEU D 122
LEU D 140
PHE D 137
None
1.16A 3k2hA-2ynmD:
undetectable
3k2hA-2ynmD:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 ALA D 203
ILE D  19
LEU D 122
LEU D 140
PHE D 137
None
1.14A 3k2hB-2ynmD:
undetectable
3k2hB-2ynmD:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
1.02A 3k4vC-2ynmA:
undetectable
3k4vC-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 125
VAL A  83
ILE A  84
None
None
SF4  A1302 (-4.1A)
None
EPE  A1298 (-4.9A)
0.94A 3k4vD-2ynmA:
undetectable
3k4vD-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 GLY C 136
GLY C 101
SER C 133
ALA C 148
ASP C 146
SF4  C1413 ( 3.8A)
None
None
None
None
1.11A 3keeA-2ynmC:
undetectable
3keeA-2ynmC:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 GLY C 136
GLY C 101
SER C 133
ALA C 148
ASP C 146
SF4  C1413 ( 3.8A)
None
None
None
None
1.12A 3keeD-2ynmC:
undetectable
3keeD-2ynmC:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
3 / 3 ALA C  56
ARG D 381
LYS D 362
None
0.97A 3kp3B-2ynmC:
undetectable
3kp3B-2ynmC:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 THR A  82
THR A 132
GLN A 131
GLY A 117
ALA C  71
EPE  A1298 (-2.7A)
None
GOL  D1532 (-2.7A)
EPE  A1298 (-4.5A)
None
1.29A 3mg0H-2ynmA:
undetectable
3mg0I-2ynmA:
undetectable
3mg0H-2ynmA:
22.19
3mg0I-2ynmA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
1.02A 3mwsB-2ynmA:
undetectable
3mwsB-2ynmA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 8 HIS A 231
SER A 211
LEU A 293
ASP A 215
None
EPE  A1297 (-4.3A)
None
None
1.23A 3n2oC-2ynmA:
undetectable
3n2oD-2ynmA:
undetectable
3n2oC-2ynmA:
19.41
3n2oD-2ynmA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 11 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.11A 3n8yA-2ynmA:
undetectable
3n8yA-2ynmA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 125
VAL A  83
ILE A  84
None
None
SF4  A1302 (-4.1A)
None
EPE  A1298 (-4.9A)
0.92A 3nduA-2ynmA:
undetectable
3nduA-2ynmA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.98A 3nduB-2ynmA:
undetectable
3nduB-2ynmA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 125
VAL A  83
ILE A  84
None
None
SF4  A1302 (-4.1A)
None
EPE  A1298 (-4.9A)
0.93A 3nduD-2ynmA:
undetectable
3nduD-2ynmA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 ALA D 341
ILE D 350
ASN D 352
ASP D 304
GLY D 305
None
1.23A 3nrrA-2ynmD:
undetectable
3nrrA-2ynmD:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.89A 3nu3A-2ynmA:
undetectable
3nu3A-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 10 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
1.04A 3nu6B-2ynmA:
undetectable
3nu6B-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 9 LEU A  87
ALA C  71
GLY A 125
VAL A  83
ILE A  84
None
None
SF4  A1302 (-4.1A)
None
EPE  A1298 (-4.9A)
0.94A 3oxvA-2ynmA:
undetectable
3oxvA-2ynmA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 10 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.97A 3oxwD-2ynmA:
undetectable
3oxwD-2ynmA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.99A 3oxxC-2ynmA:
undetectable
3oxxC-2ynmA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 LEU A  87
ALA C  71
GLY A 125
VAL A  83
ILE A  84
None
None
SF4  A1302 (-4.1A)
None
EPE  A1298 (-4.9A)
0.99A 3oxxD-2ynmA:
undetectable
3oxxD-2ynmA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.97A 3oxxD-2ynmA:
undetectable
3oxxD-2ynmA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.92A 3oy4A-2ynmA:
undetectable
3oy4A-2ynmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 GLU D 227
GLY D 305
ASN D 130
GLY D 303
PHE D 302
None
1.28A 3ps9A-2ynmD:
undetectable
3ps9A-2ynmD:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.91A 3pwmA-2ynmA:
undetectable
3pwmA-2ynmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.98A 3pwrA-2ynmA:
undetectable
3pwrA-2ynmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.94A 3pwrB-2ynmA:
undetectable
3pwrB-2ynmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
3 / 3 HIS D 480
SER D 487
GLU D 486
None
0.87A 3s8pA-2ynmD:
undetectable
3s8pA-2ynmD:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU C  80
VAL C  37
HIS D  13
LEU C  70
TYR D  38
None
None
None
None
PMR  C1414 (-4.6A)
1.20A 3sp9B-2ynmC:
undetectable
3sp9B-2ynmC:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.99A 3tkgB-2ynmA:
undetectable
3tkgB-2ynmA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
4 / 8 THR D  56
PRO D  54
PHE D  84
SER D  51
None
1.08A 3tzfB-2ynmD:
undetectable
3tzfB-2ynmD:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 7 ARG A 187
ALA A 184
ILE A 188
GLY A 154
None
None
None
AF3  A1299 (-3.5A)
0.85A 3v4tH-2ynmA:
undetectable
3v4tH-2ynmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 6 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
1.02A 3wg7C-2ynmC:
undetectable
3wg7J-2ynmC:
undetectable
3wg7C-2ynmC:
21.92
3wg7J-2ynmC:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 6 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
0.99A 3wg7P-2ynmC:
undetectable
3wg7W-2ynmC:
undetectable
3wg7P-2ynmC:
21.92
3wg7W-2ynmC:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 7 LEU A 172
ALA A 230
VAL A 261
ILE A 207
None
0.90A 3wsjB-2ynmA:
undetectable
3wsjB-2ynmA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 ILE D 516
GLY D 485
ILE D 492
ASN D 503
LEU D 522
None
0.98A 4a81A-2ynmD:
undetectable
4a81A-2ynmD:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 6 VAL C  84
LEU C  97
ILE C 129
VAL C  37
None
0.94A 4a9kA-2ynmC:
undetectable
4a9kA-2ynmC:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 ARG C  28
VAL C 174
LEU C 178
TRP C 246
GLY C 168
None
1.13A 4coxC-2ynmC:
undetectable
4coxC-2ynmC:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.92A 4dqbA-2ynmA:
undetectable
4dqbA-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.90A 4dqeA-2ynmA:
undetectable
4dqeA-2ynmA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.87A 4dqfA-2ynmA:
undetectable
4dqfA-2ynmA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 11 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.90A 4dqhA-2ynmA:
undetectable
4dqhA-2ynmA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 6 PHE C  98
ALA C 148
PRO C 195
LEU C 152
None
1.08A 4dtzB-2ynmC:
undetectable
4dtzB-2ynmC:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 8 GLY C  38
LEU C  65
ILE C  64
THR C  41
None
None
None
SF4  C1413 ( 4.6A)
0.77A 4em2A-2ynmC:
undetectable
4em2A-2ynmC:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 4 LEU C 300
PRO C 299
LEU C 238
ILE C 387
None
0.84A 4f4dB-2ynmC:
2.8
4f4dB-2ynmC:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 4 ILE C 187
LEU C 164
LYS C 189
ASN C 183
None
1.42A 4g19D-2ynmC:
undetectable
4g19D-2ynmC:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
1.00A 4hlaA-2ynmA:
undetectable
4hlaA-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 ARG D  52
LEU C 348
ASP C 349
PRO C  12
VAL C 344
None
0.99A 4hlaA-2ynmD:
undetectable
4hlaA-2ynmD:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 5 LEU C 300
PRO C 299
LEU C 238
ILE C 387
None
0.95A 4klrA-2ynmC:
3.3
4klrA-2ynmC:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
4 / 6 GLU D  93
GLN D 103
VAL A 133
THR A 132
GOL  D1532 (-3.0A)
None
None
None
1.24A 4lnxA-2ynmD:
undetectable
4lnxA-2ynmD:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.03A 4otyA-2ynmA:
undetectable
4otyA-2ynmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.05A 4otyB-2ynmA:
undetectable
4otyB-2ynmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 GLY C 239
PHE C 236
ASN C 306
ALA C 272
ALA C 393
None
1.42A 4pclB-2ynmC:
3.7
4pclB-2ynmC:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 10 LEU D  90
LEU D  26
LEU D 215
LEU D 172
VAL D 201
None
1.04A 4po0A-2ynmD:
undetectable
4po0A-2ynmD:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.84A 4q1xB-2ynmA:
undetectable
4q1xB-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 10 ASP D 183
ILE D 188
GLY D 410
ILE D 414
VAL D 248
None
0.95A 4q1yA-2ynmD:
undetectable
4q1yA-2ynmD:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.89A 4q1yB-2ynmA:
undetectable
4q1yB-2ynmA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.16A 4rrwA-2ynmA:
undetectable
4rrwA-2ynmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.14A 4rrwB-2ynmA:
undetectable
4rrwB-2ynmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.16A 4rrzA-2ynmA:
undetectable
4rrzA-2ynmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.14A 4rrzB-2ynmA:
undetectable
4rrzB-2ynmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 PHE C 384
GLY C  18
LEU C  19
VAL C  36
THR C  62
PMR  C1414 (-4.3A)
None
SF4  C1413 (-4.3A)
None
None
1.19A 4wnwA-2ynmC:
undetectable
4wnwA-2ynmC:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 9 LEU D 120
GLY D  92
ILE D  19
MET D  23
THR D 136
None
1.36A 4x3mA-2ynmD:
undetectable
4x3mA-2ynmD:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 THR D  37
ALA D  39
ASP D  40
GLY D  92
PRO D  54
GOL  C1412 (-3.5A)
None
None
None
None
0.90A 4xi3B-2ynmD:
undetectable
4xi3B-2ynmD:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 7 SER C 133
SER C 105
GLU C 138
GLU C 106
None
1.43A 4xzkA-2ynmC:
undetectable
4xzkA-2ynmC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJQ_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 11 SER D 175
MET D 406
LEU D 224
GLU D   9
GLY D 132
None
1.25A 4zjqA-2ynmD:
0.0
4zjqA-2ynmD:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 7 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
1.00A 5b1bP-2ynmC:
undetectable
5b1bW-2ynmC:
undetectable
5b1bP-2ynmC:
21.92
5b1bW-2ynmC:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 GLY C 101
GLY C 134
ILE C 110
LEU C 112
ALA C 148
None
0.98A 5bw4B-2ynmC:
undetectable
5bw4B-2ynmC:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 ALA D 133
GLY D 178
GLY D 173
LEU D 205
LEU D 177
None
None
None
None
GOL  D1530 ( 4.6A)
1.01A 5c0oH-2ynmD:
undetectable
5c0oH-2ynmD:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 6 PHE C  16
SER C  21
LEU C  19
LEU C  45
GOL  C1412 ( 3.4A)
None
SF4  C1413 (-4.3A)
SF4  C1413 (-4.0A)
1.36A 5dzke-2ynmC:
2.4
5dzks-2ynmC:
undetectable
5dzke-2ynmC:
21.82
5dzks-2ynmC:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 11 GLU D 375
THR D 372
TYR D   8
GLY D 327
TYR D 329
None
1.34A 5e3iB-2ynmD:
undetectable
5e3iB-2ynmD:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 9 PHE D 258
GLY D 407
GLU D 409
ILE D 250
ALA D 254
None
1.45A 5entC-2ynmD:
undetectable
5entC-2ynmD:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 LEU D  90
LEU D 145
PHE D 137
ALA D 203
LEU D 172
None
1.02A 5iepA-2ynmD:
undetectable
5iepA-2ynmD:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 LEU D  90
LEU D 145
PHE D 137
ALA D 203
LEU D 172
None
1.07A 5iepA-2ynmD:
undetectable
5iepA-2ynmD:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.07A 5ikqA-2ynmA:
undetectable
5ikqA-2ynmA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.06A 5ikqB-2ynmA:
undetectable
5ikqB-2ynmA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.16A 5ikrA-2ynmA:
undetectable
5ikrA-2ynmA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
5 / 12 VAL A 152
LEU A 153
GLY A 159
ALA A 162
LEU A 165
None
1.06A 5ikrB-2ynmA:
undetectable
5ikrB-2ynmA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_1
(PROTEASE E35D-DRV)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.94A 5kqyA-2ynmA:
undetectable
5kqyA-2ynmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 9 VAL A 206
THR A 175
ASN A 177
ILE A 217
None
None
EPE  A1297 (-4.0A)
None
0.97A 5lg3I-2ynmA:
undetectable
5lg3I-2ynmA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 4 SER A  54
ALA A  51
GLN A 262
THR A 247
None
0.99A 5n0rA-2ynmA:
undetectable
5n0rA-2ynmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 4 SER A  54
ALA A  51
GLN A 262
THR A 247
None
0.96A 5n0sA-2ynmA:
undetectable
5n0sA-2ynmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 5 SER A  54
ALA A  51
GLN A 262
THR A 247
None
1.00A 5n0tA-2ynmA:
2.6
5n0tA-2ynmA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 4 SER A  54
ALA A  51
GLN A 262
THR A 247
None
1.00A 5n0wA-2ynmA:
undetectable
5n0wA-2ynmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 5 SER A  54
ALA A  51
GLN A 262
THR A 247
None
1.02A 5n0wB-2ynmA:
3.6
5n0wB-2ynmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 4 SER A  54
ALA A  51
GLN A 262
THR A 247
None
0.99A 5n0xA-2ynmA:
undetectable
5n0xA-2ynmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
3 / 3 SER A  54
ALA A  51
THR A 247
None
0.72A 5n0xB-2ynmA:
undetectable
5n0xB-2ynmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 5 SER A  54
ALA A  51
GLN A 262
THR A 247
None
1.00A 5n4iA-2ynmA:
undetectable
5n4iA-2ynmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
4 / 8 ARG D 313
ILE D 326
ASP D 304
GLY D 305
None
0.75A 5nooD-2ynmD:
undetectable
5nooD-2ynmD:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_G_ACTG704_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus;
Prochlorococcus
marinus)
4 / 5 ALA A 162
GLN D 101
LYS A 134
GLN D 103
None
GOL  D1532 (-3.3A)
GOL  D1532 (-4.0A)
None
1.20A 5odcA-2ynmA:
1.7
5odcG-2ynmA:
1.6
5odcA-2ynmA:
19.38
5odcG-2ynmA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 VAL D 369
GLU D 375
SER D 378
GLY D 327
LEU D 349
None
1.28A 5ogcB-2ynmD:
undetectable
5ogcB-2ynmD:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 5 PHE C  98
PHE C  33
LEU C  97
LEU C  19
None
None
None
SF4  C1413 (-4.3A)
1.01A 5veuH-2ynmC:
undetectable
5veuH-2ynmC:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 7 SER A 115
THR A 129
PHE A 161
PRO A 164
None
1.22A 5vkqA-2ynmA:
undetectable
5vkqB-2ynmA:
undetectable
5vkqA-2ynmA:
10.32
5vkqB-2ynmA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus)
4 / 7 SER A 115
THR A 129
PHE A 161
PRO A 164
None
1.20A 5vkqC-2ynmA:
undetectable
5vkqD-2ynmA:
undetectable
5vkqC-2ynmA:
10.32
5vkqD-2ynmA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 6 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
1.02A 5x19P-2ynmC:
undetectable
5x19P-2ynmC:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 5 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
1.03A 5x1bP-2ynmC:
undetectable
5x1bP-2ynmC:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 7 LEU C  35
PHE C  60
PHE C  33
LEU C  87
None
0.99A 5x1fP-2ynmC:
undetectable
5x1fW-2ynmC:
undetectable
5x1fP-2ynmC:
21.92
5x1fW-2ynmC:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU C 238
GLU C 297
PRO C 215
GLU C 145
THR C  20
None
None
None
None
PMR  C1414 (-3.9A)
1.47A 5xipD-2ynmC:
undetectable
5xipD-2ynmC:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 LEU C 238
GLU C 297
PRO C 215
GLU C 145
THR C  20
None
None
None
None
PMR  C1414 (-3.9A)
1.45A 5xiqB-2ynmC:
2.9
5xiqB-2ynmC:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
5 / 12 ILE C 247
ALA C 251
ALA C 250
LEU C 232
LEU C 166
None
1.05A 6a60D-2ynmC:
undetectable
6a60D-2ynmC:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 VAL D 369
GLU D 375
SER D 378
GLY D 327
LEU D 349
None
1.00A 6b0cD-2ynmD:
undetectable
6b0cD-2ynmD:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 7 PHE C 182
ARG C 184
LEU C 185
ALA C 250
None
0.76A 6b89A-2ynmC:
undetectable
6b89A-2ynmC:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
5 / 12 PHE D 179
LEU D 224
GLY D 173
VAL D 398
CYH D 181
None
1.31A 6bxnB-2ynmD:
1.8
6bxnB-2ynmD:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus)
4 / 4 HIS D  13
VAL D  55
LEU D  30
ALA D  39
None
1.06A 6d8pB-2ynmD:
3.2
6d8pB-2ynmD:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus;
Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.85A 6dgxB-2ynmA:
undetectable
6dgxB-2ynmA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus;
Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 125
VAL A  83
ILE A  84
None
None
SF4  A1302 (-4.1A)
None
EPE  A1298 (-4.9A)
1.00A 6dh6A-2ynmA:
undetectable
6dh6A-2ynmA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus;
Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 125
VAL A  83
ILE A  84
None
None
SF4  A1302 (-4.1A)
None
EPE  A1298 (-4.9A)
0.94A 6difA-2ynmA:
undetectable
6difA-2ynmA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus;
Prochlorococcus
marinus)
5 / 12 LEU A  87
ALA C  71
GLY A 126
VAL A  83
ILE A  84
None
None
SF4  A1302 (-3.9A)
None
EPE  A1298 (-4.9A)
0.98A 6difA-2ynmA:
undetectable
6difA-2ynmA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 5 THR D   7
ARG C  90
PRO C  58
ARG C  59
None
1.34A 6ew0B-2ynmD:
undetectable
6ew0B-2ynmD:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 5 THR D   7
ARG C  90
PRO C  58
ARG C  59
None
1.34A 6ew0D-2ynmD:
undetectable
6ew0D-2ynmD:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 5 THR D   7
ARG C  90
PRO C  58
ARG C  59
None
1.34A 6ew0H-2ynmD:
undetectable
6ew0H-2ynmD:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 5 THR D   7
ARG C  90
PRO C  58
ARG C  59
None
1.34A 6ew0I-2ynmD:
undetectable
6ew0I-2ynmD:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus)
4 / 6 LEU C 165
THR C 208
GLY C 205
ARG C 227
None
1.34A 6gtqB-2ynmC:
undetectable
6gtqD-2ynmC:
undetectable
6gtqB-2ynmC:
20.30
6gtqD-2ynmC:
10.65