SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ynq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9C_C_ACTC1120_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	2ynq	ESSB (Geobacillus thermodenitrific ans)	3 / 3	LYS A 242 TYR A 270 PRO A 243	None	1.42A	2j9cC-2ynqA: undetectable	2j9cC-2ynqA: 25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X7H_A_PFNA1375_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	2ynq	ESSB (Geobacillus thermodenitrific ans)	4 / 5	SER A 285 TYR A 281 PHE A 255 VAL A 263	NA A1392 ( 4.9A) MLI A1391 (-4.7A) None None	1.49A	2x7hA-2ynqA: undetectable	2x7hA-2ynqA: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X7H_B_PFNB1372_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	2ynq	ESSB (Geobacillus thermodenitrific ans)	4 / 5	SER A 285 TYR A 281 PHE A 255 VAL A 263	NA A1392 ( 4.9A) MLI A1391 (-4.7A) None None	1.48A	2x7hB-2ynqA: undetectable	2x7hB-2ynqA: 17.03