SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2yoc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 7 LEU A 454
TYR A 937
HIS A 415
TYR A 891
 None
 0.99A 1afsA-2yocA:
5.6		 1afsA-2yocA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 7 LEU A 454
TYR A 937
HIS A 415
TYR A 891
 None
 1.00A 1afsB-2yocA:
2.3		 1afsB-2yocA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 VAL A 308
VAL A 306
TRP A 334
 None
 0.97A 1av2C-2yocA:
undetectable
1av2D-2yocA:
undetectable		 1av2C-2yocA:
1.73
1av2D-2yocA:
1.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ASP A 822
ASP A 590
LEU A 666
GLY A 693
PHE A 862
 None
 1.38A 1d4fA-2yocA:
undetectable		 1d4fA-2yocA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ASP A 822
ASP A 590
LEU A 666
GLY A 693
PHE A 862
 None
 1.37A 1d4fB-2yocA:
undetectable		 1d4fB-2yocA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ASP A 822
ASP A 590
LEU A 666
GLY A 693
PHE A 862
 None
 1.37A 1d4fC-2yocA:
undetectable		 1d4fC-2yocA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ASP A 822
ASP A 590
LEU A 666
GLY A 693
PHE A 862
 None
 1.31A 1d4fD-2yocA:
undetectable		 1d4fD-2yocA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 LEU A 760
ALA A1048
ALA A1004
VAL A 765
GLN A 744
 None
 1.23A 1hbpA-2yocA:
undetectable		 1hbpA-2yocA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 LEU A 760
ALA A1048
ALA A1004
VAL A 765
GLN A 744
 None
 1.28A 1kt4A-2yocA:
undetectable		 1kt4A-2yocA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 GLU A 513
ASN A 517
TRP A 885
 None
 1.25A 1r15C-2yocA:
undetectable		 1r15C-2yocA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 GLU A 513
ASN A 517
TRP A 885
 None
 1.25A 1r15D-2yocA:
undetectable		 1r15D-2yocA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 GLU A 513
ASN A 517
TRP A 885
 None
 1.25A 1r15E-2yocA:
undetectable		 1r15E-2yocA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 TYR A  96
ALA A 158
GLY A 161
VAL A  28
PRO A  26
 None
 1.23A 1vpoH-2yocA:
5.0
1vpoL-2yocA:
undetectable		 1vpoH-2yocA:
10.95
1vpoL-2yocA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 6 ARG A 640
GLU A 638
PRO A 671
ALA A 673
 None
 1.44A 2ejfB-2yocA:
undetectable		 2ejfB-2yocA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ALA A 647
ILE A 646
ALA A 673
LEU A 712
PHE A 664
 None
 1.16A 2h42B-2yocA:
undetectable		 2h42B-2yocA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 PRO A 925
LEU A 753
ALA A1004
GLN A 847
ILE A 830
 None
 1.29A 2jjpA-2yocA:
undetectable		 2jjpA-2yocA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 VAL A 308
PHE A 296
THR A 324
VAL A 294
LEU A 340
 None
 1.28A 2jn3A-2yocA:
undetectable		 2jn3A-2yocA:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 LEU A 774
LEU A 771
ARG A 773
ILE A 798
ASP A 789
 None
 1.22A 2q6hA-2yocA:
undetectable		 2q6hA-2yocA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 8 LEU A 272
ARG A 325
PRO A 354
VAL A 351
 None
SO4  A2078 ( 4.1A)
None
None
 1.21A 2qd2A-2yocA:
undetectable		 2qd2A-2yocA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
ASP A 665
GLU A 694
HIS A 821
ASP A 822
 None
 0.35A 3aicA-2yocA:
undetectable		 3aicA-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
GLU A 694
ARG A 725
HIS A 821
ASP A 822
 None
None
SO4  A2076 (-3.2A)
None
None
 0.76A 3aicA-2yocA:
undetectable		 3aicA-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
ASP A 665
GLU A 694
HIS A 821
ASP A 822
 None
 0.37A 3aicB-2yocA:
5.0		 3aicB-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		6 / 12 ARG A 663
ASP A 665
GLU A 694
HIS A 821
ASP A 822
TYR A 547
 None
 0.41A 3aicC-2yocA:
4.5		 3aicC-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
ASP A 665
GLU A 694
HIS A 821
ASP A 822
 None
 0.43A 3aicD-2yocA:
4.6		 3aicD-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
GLU A 694
ARG A 725
HIS A 821
ASP A 822
 None
None
SO4  A2076 (-3.2A)
None
None
 0.74A 3aicD-2yocA:
4.6		 3aicD-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		6 / 12 ARG A 663
ASP A 665
GLU A 694
ARG A 725
HIS A 821
ASP A 822
 None
None
None
SO4  A2076 (-3.2A)
None
None
 0.73A 3aicE-2yocA:
5.1		 3aicE-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
ASP A 665
GLU A 694
HIS A 821
ASP A 822
 None
 0.42A 3aicF-2yocA:
4.4		 3aicF-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
GLU A 694
ARG A 725
HIS A 821
ASP A 822
 None
None
SO4  A2076 (-3.2A)
None
None
 0.77A 3aicF-2yocA:
4.4		 3aicF-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
ASP A 665
GLU A 694
HIS A 821
ASP A 822
 None
 0.42A 3aicG-2yocA:
2.9		 3aicG-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
GLU A 694
ARG A 725
HIS A 821
ASP A 822
 None
None
SO4  A2076 (-3.2A)
None
None
 0.80A 3aicG-2yocA:
2.9		 3aicG-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
ASP A 665
GLU A 694
HIS A 821
ASP A 822
 None
 0.38A 3aicH-2yocA:
4.7		 3aicH-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
GLU A 694
ARG A 725
HIS A 821
ASP A 822
 None
None
SO4  A2076 (-3.2A)
None
None
 0.76A 3aicH-2yocA:
4.7		 3aicH-2yocA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 THR A 374
SER A 558
LYS A 436
 None
 1.08A 3aocC-2yocA:
undetectable		 3aocC-2yocA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 5 ILE A 675
PHE A 664
ASP A 665
GLU A 694
 None
 1.16A 3kp6A-2yocA:
undetectable
3kp6B-2yocA:
undetectable		 3kp6A-2yocA:
10.16
3kp6B-2yocA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 7 ASP A 665
GLN A 700
GLN A 709
GLU A 694
 None
CA  A2074 ( 4.5A)
None
None
 1.24A 3l2vA-2yocA:
undetectable		 3l2vA-2yocA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 SER A 327
ASP A 242
ASN A 240
 None
SO4  A2078 (-4.4A)
None
 1.00A 3lsfB-2yocA:
undetectable
3lsfE-2yocA:
undetectable		 3lsfB-2yocA:
13.07
3lsfE-2yocA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 SER A 727
ILE A 746
GLY A 749
ALA A 750
LEU A 760
 None
 1.02A 3n8yA-2yocA:
undetectable		 3n8yA-2yocA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 SER A 727
ILE A 746
GLY A 749
ALA A 750
LEU A 760
 None
 1.06A 3n8yB-2yocA:
undetectable		 3n8yB-2yocA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 9 THR A 249
ALA A 251
SER A 262
THR A 264
VAL A 266
 None
 1.25A 3ozkA-2yocA:
3.2		 3ozkA-2yocA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 7 ALA A 251
SER A 262
THR A 264
VAL A 266
 None
 0.91A 3ozkB-2yocA:
undetectable		 3ozkB-2yocA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 5 ASN A 911
ASP A 878
GLU A 694
SER A 910
 None
 1.36A 3p2kC-2yocA:
undetectable		 3p2kC-2yocA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 LYS A 580
VAL A 587
HIS A 461
 None
 1.20A 3tj7A-2yocA:
undetectable		 3tj7A-2yocA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRI_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 10 TYR A 559
TYR A 437
VAL A 467
ILE A 659
ILE A 576
 None
 1.47A 3vriA-2yocA:
undetectable
3vriC-2yocA:
undetectable		 3vriA-2yocA:
13.59
3vriC-2yocA:
2.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 ASP A 199
ARG A  24
LYS A 203
 None
 1.20A 3wipG-2yocA:
undetectable		 3wipG-2yocA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 8 ARG A 904
MET A 902
TYR A 832
THR A 876
 None
 1.19A 3wipF-2yocA:
undetectable
3wipJ-2yocA:
undetectable		 3wipF-2yocA:
12.63
3wipJ-2yocA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 ARG A 223
PHE A 224
PRO A 225
 None
 0.75A 3zoaB-2yocA:
16.6		 3zoaB-2yocA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 PRO A 178
GLY A 179
GLY A 180
ASP A 120
ASP A 182
 None
 1.05A 4b17A-2yocA:
undetectable		 4b17A-2yocA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 6 PHE A 662
PHE A 691
ALA A 647
LEU A 685
 None
 1.01A 4ejgD-2yocA:
undetectable		 4ejgD-2yocA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 7 PHE A 664
PHE A 662
THR A 654
ILE A 689
PHE A 691
 None
 1.49A 4ejjA-2yocA:
undetectable		 4ejjA-2yocA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 8 ASP A 665
ASP A 878
ASP A 907
GLU A 694
 None
 1.06A 4feuD-2yocA:
undetectable		 4feuD-2yocA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 GLY A 806
GLY A 795
LEU A 712
SER A 708
GLY A 716
 None
 0.93A 4fp9A-2yocA:
undetectable		 4fp9A-2yocA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 GLY A 806
GLY A 795
LEU A 712
SER A 708
GLY A 716
 None
 0.94A 4fp9C-2yocA:
undetectable		 4fp9C-2yocA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 GLY A 806
GLY A 795
LEU A 712
SER A 708
GLY A 716
 None
 0.93A 4fp9D-2yocA:
undetectable		 4fp9D-2yocA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 GLY A 806
GLY A 795
LEU A 712
SER A 708
GLY A 716
 None
 0.93A 4fp9F-2yocA:
undetectable		 4fp9F-2yocA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 GLY A 806
GLY A 795
LEU A 712
SER A 708
GLY A 716
 None
 0.91A 4fzvA-2yocA:
undetectable		 4fzvA-2yocA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 10 GLN A 484
ASP A 884
ASN A 544
ASP A 541
SER A 558
 None
None
SO4  A2077 ( 4.7A)
CA  A2072 (-3.4A)
None
 1.45A 4gkhE-2yocA:
0.0
4gkhF-2yocA:
0.0		 4gkhE-2yocA:
12.06
4gkhF-2yocA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 SER A 558
GLN A 484
ASP A 884
ASN A 544
ASP A 541
 None
None
None
SO4  A2077 ( 4.7A)
CA  A2072 (-3.4A)
 1.42A 4gkiA-2yocA:
0.0
4gkiB-2yocA:
0.0		 4gkiA-2yocA:
12.06
4gkiB-2yocA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 GLN A 484
ASP A 884
ASN A 544
ASP A 541
SER A 558
 None
None
SO4  A2077 ( 4.7A)
CA  A2072 (-3.4A)
None
 1.41A 4gkiI-2yocA:
0.0
4gkiJ-2yocA:
0.0		 4gkiI-2yocA:
12.06
4gkiJ-2yocA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 THR A 967
ASP A 770
ASP A 787
ILE A 798
GLU A 797
 None
 1.29A 4i41A-2yocA:
undetectable		 4i41A-2yocA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 8 SER A 947
LYS A 406
ALA A 407
LEU A 952
 None
 0.93A 4ikjA-2yocA:
undetectable
4ikjB-2yocA:
undetectable		 4ikjA-2yocA:
8.82
4ikjB-2yocA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 HIS A 767
GLY A 805
ILE A 798
 None
 0.59A 4k50A-2yocA:
undetectable		 4k50A-2yocA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 HIS A 767
GLY A 805
ILE A 798
 None
 0.58A 4k50I-2yocA:
undetectable		 4k50I-2yocA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 GLY A 745
GLY A 730
GLY A 731
ALA A 750
GLN A 742
 None
 1.17A 4l8fB-2yocA:
undetectable		 4l8fB-2yocA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 GLY A 745
GLY A 730
GLY A 731
ALA A 750
GLN A 742
 None
 1.06A 4l8fD-2yocA:
undetectable		 4l8fD-2yocA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 6 GLU A 475
GLU A 377
TYR A 378
GLU A 564
 CA  A2071 (-3.0A)
None
None
None
 1.14A 4mi4A-2yocA:
undetectable		 4mi4A-2yocA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 7 GLU A 475
GLU A 377
TYR A 378
GLU A 564
 CA  A2071 (-3.0A)
None
None
None
 1.12A 4mi4B-2yocA:
undetectable
4mi4C-2yocA:
undetectable		 4mi4B-2yocA:
10.09
4mi4C-2yocA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 7 GLU A 475
GLU A 377
TYR A 378
GLU A 564
 CA  A2071 (-3.0A)
None
None
None
 1.12A 4mi4A-2yocA:
undetectable
4mi4C-2yocA:
undetectable		 4mi4A-2yocA:
10.09
4mi4C-2yocA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 8 GLU A 475
GLU A 377
TYR A 378
GLU A 564
 CA  A2071 (-3.0A)
None
None
None
 1.14A 4mj8A-2yocA:
undetectable
4mj8C-2yocA:
undetectable		 4mj8A-2yocA:
9.55
4mj8C-2yocA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 8 GLU A 475
GLU A 377
TYR A 378
GLU A 564
 CA  A2071 (-3.0A)
None
None
None
 1.13A 4mj8B-2yocA:
undetectable
4mj8C-2yocA:
undetectable		 4mj8B-2yocA:
9.55
4mj8C-2yocA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 7 GLU A 475
GLU A 377
TYR A 378
GLU A 564
 CA  A2071 (-3.0A)
None
None
None
 1.36A 4mj8C-2yocA:
undetectable		 4mj8C-2yocA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 8 TYR A 547
TRP A 545
HIS A 418
PHE A 862
 None
 1.10A 4tzcB-2yocA:
undetectable
4tzcD-2yocA:
undetectable		 4tzcB-2yocA:
6.72
4tzcD-2yocA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 8 GLY A 775
TYR A 800
SER A 727
ASN A 779
 None
 1.04A 4wrzA-2yocA:
undetectable		 4wrzA-2yocA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 7 GLY A 775
TYR A 800
SER A 721
ASN A 779
 None
 1.14A 4ws0A-2yocA:
undetectable		 4ws0A-2yocA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 8 GLN A 531
SER A 874
PHE A 886
SER A 882
 None
 0.86A 4ws1A-2yocA:
undetectable		 4ws1A-2yocA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 8 GLY A 775
TYR A 800
SER A 721
SER A 727
ASN A 779
 None
 1.24A 4ws1A-2yocA:
undetectable		 4ws1A-2yocA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 VAL A  86
TYR A  66
ILE A  44
ILE A 111
ASN A 112
 None
 0.93A 4xueA-2yocA:
1.4		 4xueA-2yocA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		3 / 3 LEU A 176
VAL A 271
ASP A 274
 None
 0.65A 4y8wC-2yocA:
undetectable		 4y8wC-2yocA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 8 ALA A1004
PRO A1005
GLY A 974
ALA A 973
GLY A 751
 None
 1.41A 4zjzB-2yocA:
undetectable		 4zjzB-2yocA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ARG A 663
ASP A 665
GLU A 694
HIS A 821
ASP A 822
 None
 0.83A 5csyB-2yocA:
2.9		 5csyB-2yocA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 VAL A 462
MET A 447
TYR A 891
SER A 417
GLN A 865
 None
 1.39A 5g6sA-2yocA:
0.9
5g6sG-2yocA:
0.9		 5g6sA-2yocA:
15.78
5g6sG-2yocA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 VAL A 462
MET A 447
TYR A 891
SER A 417
GLN A 865
 None
 1.42A 5g6sB-2yocA:
0.9
5g6sC-2yocA:
0.8		 5g6sB-2yocA:
15.78
5g6sC-2yocA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 SER A 417
GLN A 865
VAL A 462
MET A 447
TYR A 891
 None
 1.39A 5g6sB-2yocA:
undetectable
5g6sC-2yocA:
undetectable		 5g6sB-2yocA:
15.78
5g6sC-2yocA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 VAL A 462
MET A 447
TYR A 891
SER A 417
GLN A 865
 None
 1.39A 5g6sE-2yocA:
0.9
5g6sH-2yocA:
0.3		 5g6sE-2yocA:
15.78
5g6sH-2yocA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 10 SER A 417
GLN A 865
VAL A 462
MET A 447
TYR A 891
 None
 1.43A 5g6sD-2yocA:
0.3
5g6sF-2yocA:
0.3		 5g6sD-2yocA:
15.78
5g6sF-2yocA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 10 SER A 417
GLN A 865
VAL A 462
MET A 447
TYR A 891
 None
 1.43A 5g6sA-2yocA:
0.5
5g6sG-2yocA:
0.3		 5g6sA-2yocA:
15.78
5g6sG-2yocA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_H_RAUH400_1
(IMINE REDUCTASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 10 SER A 417
GLN A 865
VAL A 462
MET A 447
TYR A 891
 None
 1.42A 5g6sE-2yocA:
0.3
5g6sH-2yocA:
0.3		 5g6sE-2yocA:
15.78
5g6sH-2yocA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 ALA A 471
PHE A 691
ILE A 689
PHE A 664
THR A 596
 None
 1.33A 5jlcA-2yocA:
undetectable		 5jlcA-2yocA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 7 VAL A 351
HIS A 353
PRO A 354
THR A 302
 None
 0.97A 5vkqA-2yocA:
undetectable
5vkqD-2yocA:
undetectable		 5vkqA-2yocA:
21.31
5vkqD-2yocA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSC_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 GLY A 909
SER A 874
ASN A 911
TYR A 832
GLN A 525
 None
 1.48A 5vscA-2yocA:
undetectable		 5vscA-2yocA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSE_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 12 GLY A 909
SER A 874
ASN A 911
TYR A 832
GLN A 525
 None
 1.50A 5vseB-2yocA:
undetectable		 5vseB-2yocA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		4 / 4 LEU A 245
ASP A 242
GLN A 246
VAL A 626
 None
SO4  A2078 (-4.4A)
SO4  A2078 (-3.5A)
None
 1.32A 6bzoF-2yocA:
undetectable		 6bzoF-2yocA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 11 ASP A 863
SER A 867
VAL A 728
GLY A 745
ALA A 758
 None
 1.34A 6hu9A-2yocA:
undetectable
6hu9E-2yocA:
undetectable
6hu9I-2yocA:
undetectable		 6hu9A-2yocA:
18.43
6hu9E-2yocA:
11.38
6hu9I-2yocA:
5.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 10 ASP A 863
SER A 867
VAL A 728
GLY A 730
ALA A 758
 None
 1.45A 6hu9L-2yocA:
undetectable
6hu9P-2yocA:
undetectable
6hu9T-2yocA:
undetectable		 6hu9L-2yocA:
18.43
6hu9P-2yocA:
11.38
6hu9T-2yocA:
5.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2yoc PULLULANASE
(Klebsiella
oxytoca) 		5 / 10 ASP A 863
SER A 867
VAL A 728
GLY A 745
ALA A 758
 None
 1.33A 6hu9L-2yocA:
undetectable
6hu9P-2yocA:
undetectable
6hu9T-2yocA:
undetectable		 6hu9L-2yocA:
18.43
6hu9P-2yocA:
11.38
6hu9T-2yocA:
5.17